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Volumn 24, Issue 12 I, 2004, Pages 1759-1783

Implications for atypical antipsychotics in the treatment of schizophrenia: Neurocognition effects and a neuroprotective hypothesis

Author keywords

Atypical antipsychotics; Cognition; Schizophrenia

Indexed keywords

6 QUINOXALINECARBOXYLIC ACID PIPERIDIDE; AMPA RECEPTOR; ANTICONVULSIVE AGENT; APOLIPOPROTEIN; ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; BENZATROPINE; BENZODIAZEPINE DERIVATIVE; CALCIUM CHANNEL; CATECHOL METHYLTRANSFERASE; CHLORPROMAZINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINESTERASE INHIBITOR; CLOZAPINE; DIZOCILPINE; FLUOXETINE; HALOPERIDOL; LEVODOPA; LITHIUM; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE GROWTH FACTOR; NEUROLEPTIC AGENT; NEUROTENSIN; OLANZAPINE; PHYSOSTIGMINE; QUETIAPINE; RISPERIDONE; RIVASTIGMINE; VALPROIC ACID; ZIPRASIDONE;

EID: 9644278029     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.24.17.1759.52346     Document Type: Review
Times cited : (44)

References (87)
  • 3
    • 0035666578 scopus 로고    scopus 로고
    • The early stages of schizophrenia: Speculations on the pathogenesis, pathophysiology and therapeutic approaches
    • Lieberman JA, Perkins D, Belger A, et al. The early stages of schizophrenia: speculations on the pathogenesis, pathophysiology and therapeutic approaches. Biol Psychiatry 2001;50:884-97.
    • (2001) Biol Psychiatry , vol.50 , pp. 884-897
    • Lieberman, J.A.1    Perkins, D.2    Belger, A.3
  • 4
    • 0029918481 scopus 로고    scopus 로고
    • What are the functional consequences of neurocognitive deficits in schizophrenia?
    • Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 1996;153:321-30.
    • (1996) Am J Psychiatry , vol.153 , pp. 321-330
    • Green, M.F.1
  • 5
    • 0035663583 scopus 로고    scopus 로고
    • New perspectives on the neurobiology of schizophrenia and the role of atypical antipsychotics
    • Nemeroff CB. New perspectives on the neurobiology of schizophrenia and the role of atypical antipsychotics. Biol Psychiatry 2001;50:823-4.
    • (2001) Biol Psychiatry , vol.50 , pp. 823-824
    • Nemeroff, C.B.1
  • 8
    • 0035134442 scopus 로고    scopus 로고
    • Progressive brain volume changes and the clinical course of schizophrenia in men: A longitudinal magnetic resonance imaging study
    • Mathalon DH, Sullivan EV, Lim KO, Pfefferbaum A. Progressive brain volume changes and the clinical course of schizophrenia in men: a longitudinal magnetic resonance imaging study. Arch Gen Psychiatry 2001;58:148-57.
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 148-157
    • Mathalon, D.H.1    Sullivan, E.V.2    Lim, K.O.3    Pfefferbaum, A.4
  • 9
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman P. Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse 1987;1:133-52.
    • (1987) Synapse , vol.1 , pp. 133-152
    • Seeman, P.1
  • 10
    • 0037219236 scopus 로고    scopus 로고
    • Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia
    • Weiss AP, Schacter, DL, Goff DC, et al. Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia. Biol Psychiatry 2003;53:48-55.
    • (2003) Biol Psychiatry , vol.53 , pp. 48-55
    • Weiss, A.P.1    Schacter, D.L.2    Goff, D.C.3
  • 11
    • 0037219327 scopus 로고    scopus 로고
    • Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophrenia
    • PerIstein WM, Dixie NK, Carter CS, Noll DC, Cohen JD. Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophrenia. Biol Psychiatry 2003;53:25-38.
    • (2003) Biol Psychiatry , vol.53 , pp. 25-38
    • PerIstein, W.M.1    Dixie, N.K.2    Carter, C.S.3    Noll, D.C.4    Cohen, J.D.5
  • 12
    • 0242380353 scopus 로고    scopus 로고
    • Selective deficit of hippocampal N-acetylaspartate in antipsychotic-naive patients with schizophrenia
    • Fannon D, Simmons A, Tennakoon L, et al. Selective deficit of hippocampal N-acetylaspartate in antipsychotic-naive patients with schizophrenia. Biol Psychiatry 2003;54:587-98.
    • (2003) Biol Psychiatry , vol.54 , pp. 587-598
    • Fannon, D.1    Simmons, A.2    Tennakoon, L.3
  • 13
    • 0029054654 scopus 로고
    • An in vivo study of the prefrontal cortex of schizophrenic patients at different stages of illness via phosphorus magnetic resonance spectroscopy
    • Stanley JA, Williamson PC, Drost DJ, et al. An in vivo study of the prefrontal cortex of schizophrenic patients at different stages of illness via phosphorus magnetic resonance spectroscopy. Arch Gen Psychiatry 1995;52:399-406.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 399-406
    • Stanley, J.A.1    Williamson, P.C.2    Drost, D.J.3
  • 14
    • 0035660267 scopus 로고    scopus 로고
    • Prefrontal neurons and the genetics of schizophrenia
    • Weinberger DR, Egan MF, Bertolino A, et al. Prefrontal neurons and the genetics of schizophrenia. Biol Psychiatry 2001;50:825-44.
    • (2001) Biol Psychiatry , vol.50 , pp. 825-844
    • Weinberger, D.R.1    Egan, M.F.2    Bertolino, A.3
  • 17
    • 0035660215 scopus 로고    scopus 로고
    • 2 receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient
    • 2 receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry 2001;50:873-83.
    • (2001) Biol Psychiatry , vol.50 , pp. 873-883
    • Kapur, S.1    Remington, G.2
  • 18
    • 0030773618 scopus 로고    scopus 로고
    • Glutamate in schizophrenia: Clinical and research implications
    • Goff DC, Coyle JT. Glutamate in schizophrenia: clinical and research implications. Schizophrenia Res 1997;27:157-68.
    • (1997) Schizophrenia Res , vol.27 , pp. 157-168
    • Goff, D.C.1    Coyle, J.T.2
  • 19
    • 0031979134 scopus 로고    scopus 로고
    • Schizophrenia and glutamatergic transmission
    • Tamminga CA. Schizophrenia and glutamatergic transmission. Crit Rev Neurobiol 1998;12:21-36.
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 21-36
    • Tamminga, C.A.1
  • 21
    • 0034843738 scopus 로고    scopus 로고
    • The emerging role of glutamate in the pathophysiology and treatment of schizophrenia
    • Goff DC, Coyle JT. The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am J Psychiatry 2001;158:1367-77.
    • (2001) Am J Psychiatry , vol.158 , pp. 1367-1377
    • Goff, D.C.1    Coyle, J.T.2
  • 22
    • 0343293966 scopus 로고    scopus 로고
    • Intracellular modulation of NMD receptor function by antipsychotic drugs
    • Leveque JC, Macias W, Rajadhyaksha A, et al. Intracellular modulation of NMD receptor function by antipsychotic drugs. J Neurosci 2000;20:4011-20.
    • (2000) J Neurosci , vol.20 , pp. 4011-4020
    • Leveque, J.C.1    Macias, W.2    Rajadhyaksha, A.3
  • 23
    • 0041430707 scopus 로고    scopus 로고
    • Long-term effects of olanzapine, risperidone, and quetiapine on ionotropic glutamate receptor types: Implications for antipsychotic drug treatment
    • Tarzi FI. Long-term effects of olanzapine, risperidone, and quetiapine on ionotropic glutamate receptor types: implications for antipsychotic drug treatment. J Pharmacol Exp Ther 2003;306:1145-51.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 1145-1151
    • Tarzi, F.I.1
  • 24
    • 12244296144 scopus 로고    scopus 로고
    • The atypical antipsychotic ziprasidone, but not haloperidol, improves phencyclidine-induced cognitive deficits in a reversal learning task in the rat
    • Abdul-Monim Z, Reynolds GP, Neill JC. The atypical antipsychotic ziprasidone, but not haloperidol, improves phencyclidine-induced cognitive deficits in a reversal learning task in the rat. J Psychopharmacol 2003;17:57-68.
    • (2003) J Psychopharmacol , vol.17 , pp. 57-68
    • Abdul-Monim, Z.1    Reynolds, G.P.2    Neill, J.C.3
  • 25
    • 0031658643 scopus 로고    scopus 로고
    • Increased levels of apolipoprotein D in CSF and hippocampus of Alzheimer's patients
    • Terrisse L, Poirier J, Bertrand P, et al. Increased levels of apolipoprotein D in CSF and hippocampus of Alzheimer's patients. J Neurochem 1998;71:1643-50.
    • (1998) J Neurochem , vol.71 , pp. 1643-1650
    • Terrisse, L.1    Poirier, J.2    Bertrand, P.3
  • 27
    • 0035957393 scopus 로고    scopus 로고
    • Increased CNS levels of apolipoprotein D in schizophrenic and bipolar patients: Implications for the pathophysiology of psychiatric disorders
    • Thomas EA, Dean B, Pavey G, Sutcliff JG. Increased CNS levels of apolipoprotein D in schizophrenic and bipolar patients: implications for the pathophysiology of psychiatric disorders. Proc Natl Acad Sci U S A 2001;98:4066-71.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4066-4071
    • Thomas, E.A.1    Dean, B.2    Pavey, G.3    Sutcliff, J.G.4
  • 28
    • 0038784889 scopus 로고    scopus 로고
    • Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer's disease: No relations to apolipoprotein E expression or genotype
    • Thomas EA, Laws SM, Sutcliff JG, et al. Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer's disease: no relations to apolipoprotein E expression or genotype. Biol Psychiatry 2003;54:136-41.
    • (2003) Biol Psychiatry , vol.54 , pp. 136-141
    • Thomas, E.A.1    Laws, S.M.2    Sutcliff, J.G.3
  • 29
    • 0041430793 scopus 로고    scopus 로고
    • Antipsychotic drugs differentially modulate apolipoprotein D in rat brain
    • Khan MM, Parikh VV, Mahadik SP. Antipsychotic drugs differentially modulate apolipoprotein D in rat brain. J Neurochem 2003;86:1089-100.
    • (2003) J Neurochem , vol.86 , pp. 1089-1100
    • Khan, M.M.1    Parikh, V.V.2    Mahadik, S.P.3
  • 30
    • 0036844447 scopus 로고    scopus 로고
    • Elevated plasma levels of apolipoprotein D in schizophrenia and its treatment and outcome
    • Mahadik SP, Khan MM, Evans D, Parikh W. Elevated plasma levels of apolipoprotein D in schizophrenia and its treatment and outcome. Schizophrenia Res 2002;58:55-62.
    • (2002) Schizophrenia Res , vol.58 , pp. 55-62
    • Mahadik, S.P.1    Khan, M.M.2    Evans, D.3    Parikh, W.4
  • 31
    • 0242348828 scopus 로고    scopus 로고
    • Increased levels of apolipoprotein E in the frontal cortex of subjects with schizophrenia
    • Dean B, Laws SM, Hone E, et al. Increased levels of apolipoprotein E in the frontal cortex of subjects with schizophrenia. Biol Psychiatry 2003;54:616-22.
    • (2003) Biol Psychiatry , vol.54 , pp. 616-622
    • Dean, B.1    Laws, S.M.2    Hone, E.3
  • 32
    • 0042433479 scopus 로고    scopus 로고
    • The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: Recent challenges and their implications for novel drug development
    • Terry AV, Buccasfusco JJ. The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 2003;306:621-7.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 621-627
    • Terry, A.V.1    Buccasfusco, J.J.2
  • 33
    • 0036451765 scopus 로고    scopus 로고
    • Differential effects of chronic haloperidol and olanzapine exposure on brain cholinergic markers and spatial learning in rats
    • Terry AV, Hill WD, Parikh V, Evans DR, Waller JL, Mahadik SP. Differential effects of chronic haloperidol and olanzapine exposure on brain cholinergic markers and spatial learning in rats. Psychopharmacology 2002;164:360-8.
    • (2002) Psychopharmacology , vol.164 , pp. 360-368
    • Terry, A.V.1    Hill, W.D.2    Parikh, V.3    Evans, D.R.4    Waller, J.L.5    Mahadik, S.P.6
  • 34
    • 0037308980 scopus 로고    scopus 로고
    • Differential effect of haloperidol, risperidone, and clozapine exposure on cholinergic markers and spatial learning performance in rats
    • Terry AV, Hill WD, Parikh V, Waller JL, Evans DR, Mahadik SP. Differential effect of haloperidol, risperidone, and clozapine exposure on cholinergic markers and spatial learning performance in rats. Neuropsychopharmacology 2003;28:300-9.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 300-309
    • Terry, A.V.1    Hill, W.D.2    Parikh, V.3    Waller, J.L.4    Evans, D.R.5    Mahadik, S.P.6
  • 35
    • 0020622678 scopus 로고
    • Interactions of neurotensin and brain dopamine systems: Biochemical and behavioral studies
    • Nemeroff CB, Luttinger D, Hernandez DE, et al. Interactions of neurotensin and brain dopamine systems: biochemical and behavioral studies. J Pharmacol Exp Ther 1983;225:337-45.
    • (1983) J Pharmacol Exp Ther , vol.225 , pp. 337-345
    • Nemeroff, C.B.1    Luttinger, D.2    Hernandez, D.E.3
  • 36
    • 0035668473 scopus 로고    scopus 로고
    • The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs
    • Binder EB, Kinkead B, Owens MJ, Nemeroff CB. The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs. Biol Psychiatry 2001;50:856-72.
    • (2001) Biol Psychiatry , vol.50 , pp. 856-872
    • Binder, E.B.1    Kinkead, B.2    Owens, M.J.3    Nemeroff, C.B.4
  • 37
    • 0027102820 scopus 로고
    • 2 receptors as a major mechanism for neuroleptic-like action of neurotensin
    • 2 receptors as a major mechanism for neuroleptic-like action of neurotensin. Ann N Y Acad Sci 1992;668:186-204.
    • (1992) Ann N Y Acad Sci , vol.668 , pp. 186-204
    • Fuxe, K.1    Von Euler, G.2    Agnati, L.F.3
  • 38
    • 0037204952 scopus 로고    scopus 로고
    • The Fas signaling pathway: More than a paradigm
    • Wajant H. The Fas signaling pathway: more than a paradigm. Science 2002;296:1635-6,
    • (2002) Science , vol.296 , pp. 1635-1636
    • Wajant, H.1
  • 39
    • 0037464075 scopus 로고    scopus 로고
    • Deciphering death's circuitry
    • Lewis R. Deciphering death's circuitry. Scientist 2003;3:32-3.
    • (2003) Scientist , vol.3 , pp. 32-33
    • Lewis, R.1
  • 40
    • 0035957969 scopus 로고    scopus 로고
    • The mitochondrion: Is it central to apoptosis?
    • Finkel E. The mitochondrion: is it central to apoptosis? Science 2003;292:624-6.
    • (2003) Science , vol.292 , pp. 624-626
    • Finkel, E.1
  • 41
    • 0001343810 scopus 로고    scopus 로고
    • Bel-2 promotes regeneration of severed axons in mammalia CNS
    • Chen DF, Schneider GE, Martinou JC, Tonegawa S. Bel-2 promotes regeneration of severed axons in mammalia CNS. Nature 1997;385:434-9.
    • (1997) Nature , vol.385 , pp. 434-439
    • Chen, D.F.1    Schneider, G.E.2    Martinou, J.C.3    Tonegawa, S.4
  • 42
    • 0034307192 scopus 로고    scopus 로고
    • Cortical Bel-2 protein expression and apoptotic regulation in schizophrenia
    • Jarskog LF, Gilmore JH, Selinger ES, Liberman JA. Cortical Bel-2 protein expression and apoptotic regulation in schizophrenia. Biol Psychiatry 2000;48:641-50.
    • (2000) Biol Psychiatry , vol.48 , pp. 641-650
    • Jarskog, L.F.1    Gilmore, J.H.2    Selinger, E.S.3    Liberman, J.A.4
  • 43
    • 0041781821 scopus 로고    scopus 로고
    • The quest for the smart pill
    • Hall SS. The quest for the smart pill. Sci Am 2003;289:54-65.
    • (2003) Sci Am , vol.289 , pp. 54-65
    • Hall, S.S.1
  • 44
    • 0037215386 scopus 로고    scopus 로고
    • Expression of brain-derived neurotropics factor mRNA in rat hippocampus after treatment with antipsychotic drugs
    • Bai O, Chlan-Fourney J, Bowen R, Keegan D, Li XM. Expression of brain-derived neurotropics factor mRNA in rat hippocampus after treatment with antipsychotic drugs. J Neurosci Res 2003;71:127-31.
    • (2003) J Neurosci Res , vol.71 , pp. 127-131
    • Bai, O.1    Chlan-Fourney, J.2    Bowen, R.3    Keegan, D.4    Li, X.M.5
  • 45
    • 0037087022 scopus 로고    scopus 로고
    • Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus
    • Xu H, Qing H, Lu W, et al. Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus. Neurosci Lett 2002;321:65-8.
    • (2002) Neurosci Lett , vol.321 , pp. 65-68
    • Xu, H.1    Qing, H.2    Lu, W.3
  • 47
    • 0037205044 scopus 로고    scopus 로고
    • Signaling pathways for PC12 cell differentiation: Making the right connections
    • Vaudry D, Strok PJS, Lazarovici P, Eiden LE. Signaling pathways for PC12 cell differentiation: making the right connections. Science 2002;296:1648-9.
    • (2002) Science , vol.296 , pp. 1648-1649
    • Vaudry, D.1    Strok, P.J.S.2    Lazarovici, P.3    Eiden, L.E.4
  • 48
    • 0033118431 scopus 로고    scopus 로고
    • Differential effects of olanzapine on the gene expression of superoxide dismutase and the low affinity nerve growth factor receptor
    • Li XM, Chlan-Fourney J, Juorio AV, et al. Differential effects of olanzapine on the gene expression of superoxide dismutase and the low affinity nerve growth factor receptor. J Neurosci Res 1999;56:72-5.
    • (1999) J Neurosci Res , vol.56 , pp. 72-75
    • Li, X.M.1    Chlan-Fourney, J.2    Juorio, A.V.3
  • 49
    • 0037100215 scopus 로고    scopus 로고
    • Protective effects of atypical antipsychotic drugs on PC12 cells after serum withdrawal
    • Bai O, Wei Z, Lu W, Bowen R, Keegan D, Li XM. Protective effects of atypical antipsychotic drugs on PC12 cells after serum withdrawal. J Neurosci Res 2002;69:278-83.
    • (2002) J Neurosci Res , vol.69 , pp. 278-283
    • Bai, O.1    Wei, Z.2    Lu, W.3    Bowen, R.4    Keegan, D.5    Li, X.M.6
  • 50
    • 0043173819 scopus 로고    scopus 로고
    • Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide
    • Wei Z, Bai O, Richardson JS, Mousseau DD, Li XM. Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide. J Neurosci Res 2003;73:364-8.
    • (2003) J Neurosci Res , vol.73 , pp. 364-368
    • Wei, Z.1    Bai, O.2    Richardson, J.S.3    Mousseau, D.D.4    Li, X.M.5
  • 51
    • 0037212193 scopus 로고    scopus 로고
    • Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain
    • Parikh V, Khan M, Mahadik SP. Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J Psychiatric Res 2003;37:43-51.
    • (2003) J Psychiatric Res , vol.37 , pp. 43-51
    • Parikh, V.1    Khan, M.2    Mahadik, S.P.3
  • 52
    • 0038018122 scopus 로고    scopus 로고
    • The ability of atypical antipsychotic drugs vs haloperidol to protect PC12 cells against MPP+ induced apoptosis
    • Qing H, Xu H, Wei Z, Gibson K, Li XM. The ability of atypical antipsychotic drugs vs haloperidol to protect PC12 cells against MPP+ induced apoptosis. Eur J Neurosci 2003;17:1563-70.
    • (2003) Eur J Neurosci , vol.17 , pp. 1563-1570
    • Qing, H.1    Xu, H.2    Wei, Z.3    Gibson, K.4    Li, X.M.5
  • 53
  • 54
    • 0037393410 scopus 로고    scopus 로고
    • Nerve growth factor in never-medicated first-episode psychotic and medicated chronic schizophrenic patients: Possible implications for treatment outcome
    • Parikh V, Evans DR, Khan M, Mahadik SP. Nerve growth factor in never-medicated first-episode psychotic and medicated chronic schizophrenic patients: possible implications for treatment outcome. Schizophrenia Res 2003;60:117-23.
    • (2003) Schizophrenia Res , vol.60 , pp. 117-123
    • Parikh, V.1    Evans, D.R.2    Khan, M.3    Mahadik, S.P.4
  • 55
    • 0038059386 scopus 로고    scopus 로고
    • Modern proteomic strategies in the study of simplex neuropsychiatrie disorders
    • Rohlff C, Hollis K. Modern proteomic strategies in the study of simplex neuropsychiatrie disorders. Biol Psychiatry 2003;53:847-53.
    • (2003) Biol Psychiatry , vol.53 , pp. 847-853
    • Rohlff, C.1    Hollis, K.2
  • 56
    • 5444229871 scopus 로고    scopus 로고
    • Signal transduction abnormalities in schizophrenia: The cAMP system
    • Muly EC. Signal transduction abnormalities in schizophrenia: the cAMP system. Psychopharmacol Bull 2002;36:92-105.
    • (2002) Psychopharmacol Bull , vol.36 , pp. 92-105
    • Muly, E.C.1
  • 57
    • 0033936313 scopus 로고    scopus 로고
    • Increased levels of transcription factors Elk-1, cyclic monophosphate response element-binding protein and activating transcription factor 2 in the cerebellar vermis of schizophrenic patients
    • Kyosseva S, Elbein A, Hutton TL, et al. Increased levels of transcription factors Elk-1, cyclic monophosphate response element-binding protein and activating transcription factor 2 in the cerebellar vermis of schizophrenic patients. Arch Gen Psychiatry 2000;57:685-91.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 685-691
    • Kyosseva, S.1    Elbein, A.2    Hutton, T.L.3
  • 58
    • 0345255956 scopus 로고    scopus 로고
    • 1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor Ser897-NR1
    • 1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor Ser897-NR1. J Neurochem 2003;87:922-34.
    • (2003) J Neurochem , vol.87 , pp. 922-934
    • Dudman, J.T.1    Eaton, M.E.2    Rajadhyaksha, A.3
  • 59
    • 0344443812 scopus 로고    scopus 로고
    • Diverse psychotomimetics act through a common signaling pathway
    • Svenningsson P, Tzavara ET, Carruthors R, et al. Diverse psychotomimetics act through a common signaling pathway. Science 2003;302:1412-15.
    • (2003) Science , vol.302 , pp. 1412-1415
    • Svenningsson, P.1    Tzavara, E.T.2    Carruthors, R.3
  • 60
    • 0141645490 scopus 로고    scopus 로고
    • Communication in neuronal networks
    • Laughlin SB, Sejnowski TJ. Communication in neuronal networks. Science 2003;301:1870-4.
    • (2003) Science , vol.301 , pp. 1870-1874
    • Laughlin, S.B.1    Sejnowski, T.J.2
  • 61
    • 0037219320 scopus 로고    scopus 로고
    • Chaos and schizophrenia: Does the method fit the madness?
    • Paulis MP, Braff DL. Chaos and schizophrenia: does the method fit the madness? Biol Psychiatry 2003;53:3-11.
    • (2003) Biol Psychiatry , vol.53 , pp. 3-11
    • Paulis, M.P.1    Braff, D.L.2
  • 63
    • 0033105823 scopus 로고    scopus 로고
    • Cognition improvement in schizophrenia with novel antipsychotic medications
    • Purdon SE. Cognition improvement in schizophrenia with novel antipsychotic medications. Schizophrenia Res 1999;35:S51-60.
    • (1999) Schizophrenia Res , vol.35
    • Purdon, S.E.1
  • 65
    • 0003412410 scopus 로고
    • Department of Health and Human Services, publication no. 91-338. Washington, DC: Department of Health and Human Services
    • Guy WG. ECDEU assessment manual for psychopharmacology, revised. Department of Health and Human Services, publication no. 91-338. Washington, DC: Department of Health and Human Services, 1976.
    • (1976) ECDEU Assessment Manual for Psychopharmacology, Revised
    • Guy, W.G.1
  • 66
    • 0042634380 scopus 로고    scopus 로고
    • A Canadian multicenter trial assessing memory and executive functions in patients with schizophrenia spectrum disorders treated with olanzapine
    • Stip E, Remington GJ, Durson SM, et al. A Canadian multicenter trial assessing memory and executive functions in patients with schizophrenia spectrum disorders treated with olanzapine. J Clin Psychopharmacol 2003;23:400-4.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 400-404
    • Stip, E.1    Remington, G.J.2    Durson, S.M.3
  • 67
    • 0042887005 scopus 로고    scopus 로고
    • Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: Critical examination of confounds
    • Weickert TW, Goldbert TE, Marenco S, Biglow LB, Egan MF, Weinberger DR. Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confounds. Neuropsychopharmacology 2003;28:1491-500.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1491-1500
    • Weickert, T.W.1    Goldbert, T.E.2    Marenco, S.3    Biglow, L.B.4    Egan, M.F.5    Weinberger, D.R.6
  • 68
    • 0034785861 scopus 로고    scopus 로고
    • Clozapine enhances neurocognition and clinical symptomatology more than standard neuroleptics
    • Potkin SG, Fleming K, Jin Y, Giulasekaram B. Clozapine enhances neurocognition and clinical symptomatology more than standard neuroleptics. J Clin Psychopharmacol 2001;21:479-83.
    • (2001) J Clin Psychopharmacol , vol.21 , pp. 479-483
    • Potkin, S.G.1    Fleming, K.2    Jin, Y.3    Giulasekaram, B.4
  • 69
    • 0037079826 scopus 로고    scopus 로고
    • Negative symptom resolution and improvements in specific cognitive deficits after acute treatment in first-episode schizophrenia
    • Schuebach D, Keshavan MS, Kmiec JA, Sweeny JA. Negative symptom resolution and improvements in specific cognitive deficits after acute treatment in first-episode schizophrenia. Schizophrenia Res 2002;53:249-61.
    • (2002) Schizophrenia Res , vol.53 , pp. 249-261
    • Schuebach, D.1    Keshavan, M.S.2    Kmiec, J.A.3    Sweeny, J.A.4
  • 70
    • 0141958820 scopus 로고    scopus 로고
    • Procedural learning in schizophrenia after 6 months of double-blind treatment with olanzapine, risperidone and haloperidol
    • Purdon SE, Woodward N, Lindborg SR, Step E. Procedural learning in schizophrenia after 6 months of double-blind treatment with olanzapine, risperidone and haloperidol. Psychopharmacology 2003;169:390-7.
    • (2003) Psychopharmacology , vol.169 , pp. 390-397
    • Purdon, S.E.1    Woodward, N.2    Lindborg, S.R.3    Step, E.4
  • 71
    • 0036268294 scopus 로고    scopus 로고
    • Neurocognitive effects of clozapine, olanzapine, risperidone and haloperidol in patients with chronic schizophrenia or schizoaffective disorder
    • Bilder RM, Goldman RS, Volavka J, et al. Neurocognitive effects of clozapine, olanzapine, risperidone and haloperidol in patients with chronic schizophrenia or schizoaffective disorder. Am J Psychiatry 2002;159:1018-28.
    • (2002) Am J Psychiatry , vol.159 , pp. 1018-1028
    • Bilder, R.M.1    Goldman, R.S.2    Volavka, J.3
  • 72
    • 0037097453 scopus 로고    scopus 로고
    • The neurocognitive effects of low dose haloperidol: A two year comparison with risperidone
    • Green Mf, Marder SR, Glynn SM, et al. The neurocognitive effects of low dose haloperidol: a two year comparison with risperidone. Biol Psychiatry 2002;52:972-8.
    • (2002) Biol Psychiatry , vol.52 , pp. 972-978
    • Green, Mf.1    Marder, S.R.2    Glynn, S.M.3
  • 74
    • 0037079831 scopus 로고    scopus 로고
    • Does cognitive function improve with quetiapine in comparison to haloperidol?
    • Velligan DI, Newcomer J, Pultz J, et al. Does cognitive function improve with quetiapine in comparison to haloperidol? Schizophrenia Res 2002;53:239-48.
    • (2002) Schizophrenia Res , vol.53 , pp. 239-248
    • Velligan, D.I.1    Newcomer, J.2    Pultz, J.3
  • 76
    • 0346786359 scopus 로고    scopus 로고
    • Improvement in cognitive function following a switch to ziprasidone from conventional antipsychotics, olanzapine or risperidone in outpatients with schizophrenia
    • Harvery PD, Meltzer H, Simpson GM, et al. Improvement in cognitive function following a switch to ziprasidone from conventional antipsychotics, olanzapine or risperidone in outpatients with schizophrenia. Schizophrenia Res 2004;66:101-13.
    • (2004) Schizophrenia Res , vol.66 , pp. 101-113
    • Harvery, P.D.1    Meltzer, H.2    Simpson, G.M.3
  • 77
    • 0141595222 scopus 로고    scopus 로고
    • Comparative effects of risperidone and olanzapine on cognition in elderly patients with schizophrenia or schizoaffective disorder
    • Harvey PD, Napolitan JA, Mao L, Gharabawi G. Comparative effects of risperidone and olanzapine on cognition in elderly patients with schizophrenia or schizoaffective disorder. Int J Geriatr Psychiatry 2003;18:820-8.
    • (2003) Int J Geriatr Psychiatry , vol.18 , pp. 820-828
    • Harvey, P.D.1    Napolitan, J.A.2    Mao, L.3    Gharabawi, G.4
  • 78
    • 0032968147 scopus 로고    scopus 로고
    • Pharmacologic strategies for augmenting cognitive performance in schizophrenia
    • Freidman JI, Temprini H, Davis KL. Pharmacologic strategies for augmenting cognitive performance in schizophrenia. Biol Psychiatry 1999;45:1-16.
    • (1999) Biol Psychiatry , vol.45 , pp. 1-16
    • Freidman, J.I.1    Temprini, H.2    Davis, K.L.3
  • 79
    • 0344306578 scopus 로고    scopus 로고
    • Effects of rivastigmine on cognitive function and quality of life in patients with schizophrenia
    • Lenzl A, Maltini E, Poggi E, Fabrizo L, Coli E. Effects of rivastigmine on cognitive function and quality of life in patients with schizophrenia. Clin Neuropharmacol 2003;26:317-21.
    • (2003) Clin Neuropharmacol , vol.26 , pp. 317-321
    • Lenzl, A.1    Maltini, E.2    Poggi, E.3    Fabrizo, L.4    Coli, E.5
  • 81
    • 0034796599 scopus 로고    scopus 로고
    • A placebo-controlled pilot study of the ampakine CX 516 added to clozapine in schizophrenia
    • Goff DC, Leahy L, Herman I, et al. A placebo-controlled pilot study of the ampakine CX 516 added to clozapine in schizophrenia. J Clin Psychopharmacol 2001;21:484-7.
    • (2001) J Clin Psychopharmacol , vol.21 , pp. 484-487
    • Goff, D.C.1    Leahy, L.2    Herman, I.3
  • 82
    • 0242497620 scopus 로고    scopus 로고
    • The architecture of cognitive control in the human prefrontal cortex
    • Koechlin E, Ody C, Kouneiher F. The architecture of cognitive control in the human prefrontal cortex. Science 2003;302:1181-5.
    • (2003) Science , vol.302 , pp. 1181-1185
    • Koechlin, E.1    Ody, C.2    Kouneiher, F.3
  • 83
    • 0346277091 scopus 로고    scopus 로고
    • Decoding schizophrenia
    • Javih DC, Coyle JT. Decoding schizophrenia. Sci Am 2004;290:48-55.
    • (2004) Sci Am , vol.290 , pp. 48-55
    • Javih, D.C.1    Coyle, J.T.2
  • 84
    • 9644266000 scopus 로고    scopus 로고
    • Depression III
    • Manji H. Depression III [editorial]. Am J Psychiatry 2003;160:24.
    • (2003) Am J Psychiatry , vol.160 , pp. 24
    • Manji, H.1
  • 85
    • 0037097412 scopus 로고    scopus 로고
    • Another view of therapy for cognition in schizophrenia
    • Carpenter WT. Another view of therapy for cognition in schizophrenia. Biol Psychiatry 2002;52:969-71.
    • (2002) Biol Psychiatry , vol.52 , pp. 969-971
    • Carpenter, W.T.1
  • 86
    • 0142011201 scopus 로고    scopus 로고
    • Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome
    • Woods SW, Brier A, Zipursky RB, et al. Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome. Biol Psychiatry 2003;54:453-64.
    • (2003) Biol Psychiatry , vol.54 , pp. 453-464
    • Woods, S.W.1    Brier, A.2    Zipursky, R.B.3


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