Deciphering death's circuitry

Scientist

Volumn 17, Issue 6, 2003, Pages 32-34

  Lewis, Ricki ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN BIM; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL ORGANELLE; CELL SURFACE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; SEQUENCE HOMOLOGY;

EID: 0037464075     PISSN: 08903670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. M.C. Wei et al., "Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death," Science, 292:727-30, April 27, 2001. (Cited in 205 papers)
2. 3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis," Mol Cell, 8:705-11, September 2001. (Cited in 87 papers)
3. D.M. Hockenbery et al., "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death," Nature, 348:334-6, 1990.
4. D. Vaux, J. Adams, "Mammalian homolog of ced-3 in Caenorhabditis elegans," Nature, 335:440-4, 1988.
5. X. Liu et al., "Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c," Cell, 86:147-57, 1996.
6. S.A. Susin et al., "Bcl-2 inhibits the mitochondrial release of an apoptogenic protease," J Exp Med, 184:1331-41, 1996.
7. L. Scorrano et al, "A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis," Dev Cell, 2:55-67, 2002.
8. 3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics," Cancer Cell, 2:183-92, September 2002.