Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms

Diabetes

Volumn 53, Issue 12, 2004, Pages 3258-3266

  Cleasby, Mark E ^a   Dzamko, Nicolas ^a   Hegarty, Bronwyn D ^a   Cooney, Gregory J ^a   Kraegen, Edward W ^a   Ye, Ji Ming ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE PHOSPHATE; C JUN AMINO TERMINAL KINASE 1; C JUN AMINO TERMINAL KINASE 2; FATTY ACID; GLUCOSE; GLYCEROL; GLYCOGEN; HEPARIN; I KAPPA B ALPHA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTRALIPID; METFORMIN; PROTEIN KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GLUCOSE CLAMP TECHNIQUE; HYPERINSULINEMIA; IMPAIRED GLUCOSE TOLERANCE; INCIDENCE; INSULIN RESISTANCE; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; LIPIDS; LIVER; MALE; METABOLIC SYNDROME X; METFORMIN; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 9444272216     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.12.3258     Document Type: Article

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