-
1
-
-
0023618126
-
Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes
-
Felber J-P, Ferrannini E, Golay A, Meye HU, Thiebaud D, Curchod B, Maeder K, Jequier E, DeFronzo RA: Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes. Diabetes 36:1341-1350, 1987
-
(1987)
Diabetes
, vol.36
, pp. 1341-1350
-
-
Felber, J.-P.1
Ferrannini, E.2
Golay, A.3
Meye, H.U.4
Thiebaud, D.5
Curchod, B.6
Maeder, K.7
Jequier, E.8
DeFronzo, R.A.9
-
2
-
-
0024244339
-
Measurement of plasma glucose free fatty acid, lactate, and insulin for 24 h in patients with NIDDM
-
Reaven GM, Hollenbeck C, Jeng CY, Wu MS, Chen YD: Measurement of plasma glucose free fatty acid, lactate, and insulin for 24 h in patients with NIDDM. Diabetes 37:1020-1024, 1988
-
(1988)
Diabetes
, vol.37
, pp. 1020-1024
-
-
Reaven, G.M.1
Hollenbeck, C.2
Jeng, C.Y.3
Wu, M.S.4
Chen, Y.D.5
-
3
-
-
0030941820
-
Metabolic defects in lean nondiabetic offspring of NIDDM parents: A cross-sectional study
-
Perseghin G, Ghosh S, Gerow K, Shulman GI: Metabolic defects in lean nondiabetic offspring of NIDDM parents: a cross-sectional study. Diabetes 46:1001-1009, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1001-1009
-
-
Perseghin, G.1
Ghosh, S.2
Gerow, K.3
Shulman, G.I.4
-
4
-
-
0026468362
-
What if minkowski had been ageusic? An alternative angle on diabetes
-
McGarry JD: What if Minkowski had been ageusic? An alternative angle on diabetes. Science 258:766-770, 1992
-
(1992)
Science
, vol.258
, pp. 766-770
-
-
McGarry, J.D.1
-
5
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G: Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:13-10, 1997
-
(1997)
Diabetes
, vol.46
, pp. 13-110
-
-
Boden, G.1
-
6
-
-
0027218865
-
Interaction between glucose and free fatty acid metabolism in human skeletal muscle
-
Kelley DE, Mokan M, Simoneau JA, Mandarino LJ: Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest 92:91-98, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 91-98
-
-
Kelley, D.E.1
Mokan, M.2
Simoneau, J.A.3
Mandarino, L.J.4
-
7
-
-
0029948212
-
Mechanism of free fatty acid-induced insulin resistance in humans
-
Roden M, Price TB, Perseghin G, Falk-Petersen K, Rothman DL, Cline GW, Shulman GI: Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 97:2859-2865, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 2859-2865
-
-
Roden, M.1
Price, T.B.2
Perseghin, G.3
Falk-Petersen, K.4
Rothman, D.L.5
Cline, G.W.6
Shulman, G.I.7
-
8
-
-
0033007561
-
Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans
-
Roden M, Krssak M, Stingl H, Gruber S, Hofer A, Fürnsinn C, Moser E, Waldhäusl W: Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans. Diabetes 48:358-364, 1999
-
(1999)
Diabetes
, vol.48
, pp. 358-364
-
-
Roden, M.1
Krssak, M.2
Stingl, H.3
Gruber, S.4
Hofer, A.5
Fürnsinn, C.6
Moser, E.7
Waldhäusl, W.8
-
9
-
-
0021691098
-
Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects
-
Bogardus C, Lillioja S, Howard BV, Reaven G, Mott D: Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects. J Clin Invest 74:1238-1246, 1984
-
(1984)
J Clin Invest
, vol.74
, pp. 1238-1246
-
-
Bogardus, C.1
Lillioja, S.2
Howard, B.V.3
Reaven, G.4
Mott, D.5
-
10
-
-
0025963777
-
The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes niellitus
-
Groop LC, Saloranta C, Shank M, Bonadonna RC, Ferrannini E, DeFronzo RA: The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes niellitus. J Clin Endocrinol Metab 72:96-107, 1991
-
(1991)
J Clin Endocrinol Metab
, vol.72
, pp. 96-107
-
-
Groop, L.C.1
Saloranta, C.2
Shank, M.3
Bonadonna, R.C.4
Ferrannini, E.5
DeFronzo, R.A.6
-
11
-
-
0027475061
-
Contribution of muscle and liver to glucose-fatty acid cycle in humans
-
Saloranta C, Koivisto V, Widen E, Falholt K, DeFronzo RA, Harkonen M, Groop L: Contribution of muscle and liver to glucose-fatty acid cycle in humans. Am J Physiol 264:E599-E605, 1993
-
(1993)
Am J Physiol
, vol.264
-
-
Saloranta, C.1
Koivisto, V.2
Widen, E.3
Falholt, K.4
DeFronzo, R.A.5
Harkonen, M.6
Groop, L.7
-
12
-
-
0021032715
-
Effect of fatty acids on glucose production and utilization in man
-
Ferrannini E, Barrett EJ, Bevilacqua S, DeFronzo RA: Effect of fatty acids on glucose production and utilization in man. J Clin Invest 72:1737-1747, 1983
-
(1983)
J Clin Invest
, vol.72
, pp. 1737-1747
-
-
Ferrannini, E.1
Barrett, E.J.2
Bevilacqua, S.3
DeFronzo, R.A.4
-
13
-
-
0024410912
-
Time dependence of the interaction between lipid and glucose in humans
-
Bonadonna RC, Zych K, Boni C, Ferrannini E, DeFronzo RA: Time dependence of the interaction between lipid and glucose in humans. Am J Physiol 257:E49-E56, 1989
-
(1989)
Am J Physiol
, vol.257
-
-
Bonadonna, R.C.1
Zych, K.2
Boni, C.3
Ferrannini, E.4
DeFronzo, R.A.5
-
14
-
-
0025872319
-
Demonstration of a novel feedback mechanism between FFA oxidation from intracellular and intravascular sources
-
Yki-Järvinen H, Puhakainen I, Saloranta C, Groop L, Taskinen MR: Demonstration of a novel feedback mechanism between FFA oxidation from intracellular and intravascular sources. Am J Physiol 260:E680-E689, 1991
-
(1991)
Am J Physiol
, vol.260
-
-
Yki-Järvinen, H.1
Puhakainen, I.2
Saloranta, C.3
Groop, L.4
Taskinen, M.R.5
-
15
-
-
0025775034
-
Effects of lipid on basal carbohydrate metabolism in normal men
-
Boden G, Jadali F: Effects of lipid on basal carbohydrate metabolism in normal men. Diabetes 40:686-692, 1991
-
(1991)
Diabetes
, vol.40
, pp. 686-692
-
-
Boden, G.1
Jadali, F.2
-
16
-
-
0026005773
-
In vivo evidence for hepatic autoregulation during FFA-stimulaled gluconeogenesis in normal humans
-
Clore JN, Glickman PS, Nestler JE, Blackard WG: In vivo evidence for hepatic autoregulation during FFA-stimulaled gluconeogenesis in normal humans. Am J Physiol 261:E425-E429, 1991
-
(1991)
Am J Physiol
, vol.261
-
-
Clore, J.N.1
Glickman, P.S.2
Nestler, J.E.3
Blackard, W.G.4
-
17
-
-
0026644792
-
Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects
-
Fulcher GR, Walker M, Catalano C, Agius L, Alberti KG: Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects. Diabetes 41:1400-1408, 1992
-
(1992)
Diabetes
, vol.41
, pp. 1400-1408
-
-
Fulcher, G.R.1
Walker, M.2
Catalano, C.3
Agius, L.4
Alberti, K.G.5
-
18
-
-
0032905885
-
The effect of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects
-
Chen X, Iqbal N, Boden G: The effect of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects. J Clin Invest 103:305-372, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 305-372
-
-
Chen, X.1
Iqbal, N.2
Boden, G.3
-
19
-
-
0025949378
-
Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus
-
Vaag A, Skött P, Gall M-A, Richter EA, Beck-Nielsen H: Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 88:1282-1290, 199I
-
(1991)
J Clin Invest
, vol.88
, pp. 1282-1290
-
-
Vaag, A.1
Skött, P.2
Gall, M.-A.3
Richter, E.A.4
Beck-Nielsen, H.5
-
20
-
-
0027515569
-
Inhibition of lipolysis decreases lipid oxidation and gluconeogenesis from lactate but not fasting hyperglycemia or total hepatic glucose production in NIDDM
-
Puhakainen I, Yki-Järvinen H: Inhibition of lipolysis decreases lipid oxidation and gluconeogenesis from lactate but not fasting hyperglycemia or total hepatic glucose production in NIDDM. Diabetes 42:1694-1699, 1993
-
(1993)
Diabetes
, vol.42
, pp. 1694-1699
-
-
Puhakainen, I.1
Yki-Järvinen, H.2
-
22
-
-
0027358353
-
Gluconeogenesis in type 2 diabetes
-
Gerich JE, Nurjhan N: Gluconeogenesis in type 2 diabetes. Adv Exp Med Biol 334:253-258, 1993
-
(1993)
Adv Exp Med Biol
, vol.334
, pp. 253-258
-
-
Gerich, J.E.1
Nurjhan, N.2
-
23
-
-
0029897538
-
Role of fat-derived substrates in the regulation of gluconeogenesis during fasting
-
Fery F, Plat L, Melot C, Balasse EO: Role of fat-derived substrates in the regulation of gluconeogenesis during fasting. Am J Physiol 270:E822-E830, 1996
-
(1996)
Am J Physiol
, vol.270
-
-
Fery, F.1
Plat, L.2
Melot, C.3
Balasse, E.O.4
-
24
-
-
0019987653
-
Insulin production rate, hepatic insulin retention and splanchnic carbohydrate metabolism after oral glucose ingestion in hyperinsulinaemic type 2 (non-insulin-dependent) diabetes mellitus
-
Waldhäusl W, Bratusch-Marrain P, Gasic S, Korn A, Nowotny P: Insulin production rate, hepatic insulin retention and splanchnic carbohydrate metabolism after oral glucose ingestion in hyperinsulinaemic type 2 (non-insulin-dependent) diabetes mellitus. Diabelologia 23:6-15, 1982
-
(1982)
Diabelologia
, vol.23
, pp. 6-15
-
-
Waldhäusl, W.1
Bratusch-Marrain, P.2
Gasic, S.3
Korn, A.4
Nowotny, P.5
-
25
-
-
0027487855
-
Estimating gluconeogenic rates in NIDDM
-
Landau BR: Estimating gluconeogenic rates in NIDDM. Adv Exp Med Biol 334:205-220, 1992
-
(1992)
Adv Exp Med Biol
, vol.334
, pp. 205-220
-
-
Landau, B.R.1
-
27
-
-
0028831071
-
A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans
-
Landau BR, Fernandez CA, Previs SF, Ekberg K, Chandramouli V, Wahren J, Kalhan SC, Brunengraber H: A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans. Am J Physiol 269:E18-E26, 1995
-
(1995)
Am J Physiol
, vol.269
-
-
Landau, B.R.1
Fernandez, C.A.2
Previs, S.F.3
Ekberg, K.4
Chandramouli, V.5
Wahren, J.6
Kalhan, S.C.7
Brunengraber, H.8
-
29
-
-
0030017082
-
Contributions of gluconeogenesis to glucose production in the fasted state
-
Landau BR, Wahren J, Chandramouli V, Schumann WC, Ekberg K, Kalhan SC: Contributions of gluconeogenesis to glucose production in the fasted state. J Clin Invest 98:378-385, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 378-385
-
-
Landau, B.R.1
Wahren, J.2
Chandramouli, V.3
Schumann, W.C.4
Ekberg, K.5
Kalhan, S.C.6
-
30
-
-
0031426379
-
Quantifying gluconeogenesis during fasting
-
Chandramouli V, Ekberg K, Schumann WC, Kalhan SC, Wahren J, Landau BR: Quantifying gluconeogenesis during fasting. Am J Physiol 36:E1209-1215, 1997
-
(1997)
Am J Physiol
, vol.36
-
-
Chandramouli, V.1
Ekberg, K.2
Schumann, W.C.3
Kalhan, S.C.4
Wahren, J.5
Landau, B.R.6
-
32
-
-
0018087989
-
Combined 17- and 18-hydroxylase deficiency associated with complete male pseudohermaphroditism and hypoaldosteronism
-
Waldhäusl W, Herkner K, Nowotny P, Bratusch-Marrain P: Combined 17- and 18-hydroxylase deficiency associated with complete male pseudohermaphroditism and hypoaldosteronism. J Clin Endocrinol Metab 46:236-240, 1978
-
(1978)
J Clin Endocrinol Metab
, vol.46
, pp. 236-240
-
-
Waldhäusl, W.1
Herkner, K.2
Nowotny, P.3
Bratusch-Marrain, P.4
-
33
-
-
0029046673
-
Effects of a 48-h fat infusion on insulin secretion and glucose utilization
-
Boden G, Cgen X, Rosner J, Barton M: Effects of a 48-h fat infusion on insulin secretion and glucose utilization. Diabetes 44:1239-1242, 1995
-
(1995)
Diabetes
, vol.44
, pp. 1239-1242
-
-
Boden, G.1
Cgen, X.2
Rosner, J.3
Barton, M.4
-
34
-
-
0014251318
-
Effect of acute elevation of plasma glycerol, triglyceride and FFA levels on glucose utilization and plasma insulin
-
Pelkonen R, Miettinen TA, Taskinen M-R, Nikkila EA: Effect of acute elevation of plasma glycerol, triglyceride and FFA levels on glucose utilization and plasma insulin. Diabetes 17:76-82, 1968
-
(1968)
Diabetes
, vol.17
, pp. 76-82
-
-
Pelkonen, R.1
Miettinen, T.A.2
Taskinen, M.-R.3
Nikkila, E.A.4
-
35
-
-
0029888870
-
Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat
-
Stein DT, Esser V, Stevenson BE, Lane KE, Whiteside JH, Daniels MB, Chen S, McGarry JD: Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. J Clin Invest 97:2728-2735, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 2728-2735
-
-
Stein, D.T.1
Esser, V.2
Stevenson, B.E.3
Lane, K.E.4
Whiteside, J.H.5
Daniels, M.B.6
Chen, S.7
McGarry, J.D.8
-
36
-
-
0014789878
-
Portal and peripheral vein immunoreactive insulin concentrations before and after glucose infusion
-
Blackard WG, Nelson NC: Portal and peripheral vein immunoreactive insulin concentrations before and after glucose infusion. Diabetes 19:302-306, 1970
-
(1970)
Diabetes
, vol.19
, pp. 302-306
-
-
Blackard, W.G.1
Nelson, N.C.2
-
37
-
-
0024392514
-
Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus: Evidence for multiple sites of insulin resistance
-
Groop LC, Bonadonna RC, DelPrato S, Ratheiser K, Zyck K, Ferrannini E, DeFronzo RA: Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus: evidence for multiple sites of insulin resistance. J Clin Invest 84:205-213, 1989
-
(1989)
J Clin Invest
, vol.84
, pp. 205-213
-
-
Groop, L.C.1
Bonadonna, R.C.2
DelPrato, S.3
Ratheiser, K.4
Zyck, K.5
Ferrannini, E.6
DeFronzo, R.A.7
-
38
-
-
0032902368
-
Effect of a selective rise in hepatic artery insulin on hepatic glucose production in the conscious dog
-
Sindelar DK, Igawa K, Chu CA, Balcom JH, Neal DW, Cherrington AD: Effect of a selective rise in hepatic artery insulin on hepatic glucose production in the conscious dog. Am J Physiol 276:E806-E813, 1999
-
(1999)
Am J Physiol
, vol.276
-
-
Sindelar, D.K.1
Igawa, K.2
Chu, C.A.3
Balcom, J.H.4
Neal, D.W.5
Cherrington, A.D.6
-
39
-
-
0030023775
-
The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans
-
Roden M, Perseghin G, Falk Petersen K, Hwang J-H, Cline GW, Gerow K, Rothman DL, Shulman GI: The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans. J Clin Invest 97:642-648, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 642-648
-
-
Roden, M.1
Perseghin, G.2
Falk Petersen, K.3
Hwang, J.-H.4
Cline, G.W.5
Gerow, K.6
Rothman, D.L.7
Shulman, G.I.8
-
40
-
-
0023026312
-
Insulin dose-response characteristics for suppression of glycerol release and conversion to glucose in humans
-
Nurjhan N, Campbell PJ, Kennedy FP, Miles JM, Gerich JE: Insulin dose-response characteristics for suppression of glycerol release and conversion to glucose in humans. Diabetes 35:1326-1331, 1986
-
(1986)
Diabetes
, vol.35
, pp. 1326-1331
-
-
Nurjhan, N.1
Campbell, P.J.2
Kennedy, F.P.3
Miles, J.M.4
Gerich, J.E.5
-
41
-
-
0032810949
-
A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo
-
Previs S, Cline GW, Shulman GI: A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo. Am J Physiol 277:E154-E160, 1999
-
(1999)
Am J Physiol
, vol.277
-
-
Previs, S.1
Cline, G.W.2
Shulman, G.I.3
-
42
-
-
0016583677
-
Splanchnic and leg exchange of glucose, amino acids, and free fatty acids during exercise in diabetes mellitus
-
Wahren J, Hagenfeldt L, Felig P: Splanchnic and leg exchange of glucose, amino acids, and free fatty acids during exercise in diabetes mellitus. J Clin Invest 55:1303-1314, 1975
-
(1975)
J Clin Invest
, vol.55
, pp. 1303-1314
-
-
Wahren, J.1
Hagenfeldt, L.2
Felig, P.3
-
43
-
-
0031060687
-
In vitro and in vivo suppression of gluconeogenesis by inhibition of pyruvate carboxylase
-
Bahl JJ, Matsuda M, DeFronzo KA, Bressler R: In vitro and in vivo suppression of gluconeogenesis by inhibition of pyruvate carboxylase. Biochem Pharmacol 53:67-74, 1997
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 67-74
-
-
Bahl, J.J.1
Matsuda, M.2
DeFronzo, K.A.3
Bressler, R.4
-
44
-
-
0025346223
-
Enhancement of hepatic glycogen by gluconeogenic precursois: Substrate flux or metabolic control?
-
Youn H, Bergman RN: Enhancement of hepatic glycogen by gluconeogenic precursois: substrate flux or metabolic control? Am J Physiol 258:E899-E906, 1990
-
(1990)
Am J Physiol
, vol.258
-
-
Youn, H.1
Bergman, R.N.2
-
45
-
-
0032737027
-
Origins of the hydrogen bound to carbon 1 of glucose in fasting: Significance in gluconeogenesis quantitation
-
Chandramouli V, Ekberg K, Schumann WC, Wahren J, Landau BR: Origins of the hydrogen bound to carbon 1 of glucose in fasting: significance in gluconeogenesis quantitation. Am J Physiol 277:E717-E723, 1999
-
(1999)
Am J Physiol
, vol.277
-
-
Chandramouli, V.1
Ekberg, K.2
Schumann, W.C.3
Wahren, J.4
Landau, B.R.5
-
46
-
-
0032520870
-
Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans
-
Peterson KF, Laurent D, Rothman DL, Cline GW, Shulman GI: Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans. J Clin Invest 101:1203-1209, 1998
-
(1998)
J Clin Invest
, vol.101
, pp. 1203-1209
-
-
Peterson, K.F.1
Laurent, D.2
Rothman, D.L.3
Cline, G.W.4
Shulman, G.I.5
-
47
-
-
0023774722
-
Pentose pathway in human liver
-
Magnusson I, Chandramouli Y, Schumann WC, Kumaran K, Wahren J, Landau BR: Pentose pathway in human liver. Proc Natl Acad U S A 85:4682-4685, 1988
-
(1988)
Proc Natl Acad U S A
, vol.85
, pp. 4682-4685
-
-
Magnusson, I.1
Chandramouli, Y.2
Schumann, W.C.3
Kumaran, K.4
Wahren, J.5
Landau, B.R.6
-
48
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner A, Laurent D, Marcucci M, Griffin ME, Dufour S, Cline GW, Slezak LA, Andersen DK, Hundal RS, Rothman FL, Petersen KF, Shulman GI: Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 103:253-259, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, F.L.10
Petersen, K.F.11
Shulman, G.I.12
-
49
-
-
0028825129
-
Free fatty acids as a link in the regulation of hepatic glucose output by peripheral insulin
-
Rebrin K, Steil GM, Getty L, Bergman RN: Free fatty acids as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes 44:1038-1045, 1995
-
(1995)
Diabetes
, vol.44
, pp. 1038-1045
-
-
Rebrin, K.1
Steil, G.M.2
Getty, L.3
Bergman, R.N.4
|