-
1
-
-
0035925596
-
Reverse vaccinology, a genome-based approach to vaccine development
-
Rappuoli R. Reverse vaccinology, a genome-based approach to vaccine development. Vaccine 2001; 19: 2688-91.
-
(2001)
Vaccine
, vol.19
, pp. 2688-2691
-
-
Rappuoli, R.1
-
2
-
-
0038542877
-
Reverse vaccinology. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. From toxin to adjuvant: The rational design of a vaccine adjuvant vector, CTA1-DD/ISCOM
-
Mora M, Veggi D, Santini L et al. Reverse vaccinology. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. From toxin to adjuvant: the rational design of a vaccine adjuvant vector, CTA1-DD/ISCOM. Drug Discov. Today 2003; 8: 459-64.
-
(2003)
Drug Discov. Today
, vol.8
, pp. 459-464
-
-
Mora, M.1
Veggi, D.2
Santini, L.3
-
3
-
-
0033787577
-
Reverse vaccinology. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
-
Rappuoli R, Pizza M, Scarlato V et al. Reverse vaccinology. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Curr. Opin. Microbiol. 2000; 3: 445-50.
-
(2000)
Curr. Opin. Microbiol.
, vol.3
, pp. 445-450
-
-
Rappuoli, R.1
Pizza, M.2
Scarlato, V.3
-
4
-
-
0034629284
-
Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
-
Pizza M, Scarlato V, Masignani V et al. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 2000; 287: 1816-20.
-
(2000)
Science
, vol.287
, pp. 1816-1820
-
-
Pizza, M.1
Scarlato, V.2
Masignani, V.3
-
5
-
-
0018376947
-
Isolation and characterization of homogeneous heat-labile enterotoxins with high specific activity from Escherichia coli cultures
-
Clements JD, Finkelstein RA. Isolation and characterization of homogeneous heat-labile enterotoxins with high specific activity from Escherichia coli cultures. Infect. Immun. 1979; 24: 760-69.
-
(1979)
Infect. Immun.
, vol.24
, pp. 760-769
-
-
Clements, J.D.1
Finkelstein, R.A.2
-
6
-
-
0018853262
-
Properties of homogeneous heat-labile enterotoxin from Escherichia coli
-
Clements JD, Yancey RJ, Finkelstein RA. Properties of homogeneous heat-labile enterotoxin from Escherichia coli. Infect. Immun. 1980; 29: 91-7.
-
(1980)
Infect. Immun.
, vol.29
, pp. 91-97
-
-
Clements, J.D.1
Yancey, R.J.2
Finkelstein, R.A.3
-
7
-
-
0027942083
-
Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis
-
Pizza M, Domenighini M, Hol W et al. Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis. Mol. Microbiol. 1994; 14: 51-60.
-
(1994)
Mol. Microbiol.
, vol.14
, pp. 51-60
-
-
Pizza, M.1
Domenighini, M.2
Hol, W.3
-
8
-
-
0027992673
-
A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the a subunit
-
Pizza M, Fontana MR, Giuliani MM et al. A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit. J. Exp. Med. 1994; 180: 2147-53.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2147-2153
-
-
Pizza, M.1
Fontana, M.R.2
Giuliani, M.M.3
-
9
-
-
0029905760
-
The adjuvant effect of a non-toxic mutant of heat-labile enterotoxin of Escherichia coli for the induction of measles virus-specific CTL responses after intranasal co-immunization with a synthetic peptide
-
Partidos CD, Pizza M, Rappuoli R, Steward MW. The adjuvant effect of a non-toxic mutant of heat-labile enterotoxin of Escherichia coli for the induction of measles virus-specific CTL responses after intranasal co-immunization with a synthetic peptide. Immunology 1996; 89: 483-7.
-
(1996)
Immunology
, vol.89
, pp. 483-487
-
-
Partidos, C.D.1
Pizza, M.2
Rappuoli, R.3
Steward, M.W.4
-
10
-
-
0032489830
-
Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
-
Giuliani MM, Del Giudice G, Giannelli V et al. Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J. Exp. Med. 1998; 187: 1123-32.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1123-1132
-
-
Giuliani, M.M.1
Del Giudice, G.2
Giannelli, V.3
-
11
-
-
0000241167
-
Hyaluronic acid biopolymers for mucosal delivery of vaccines
-
Abatangelo G, Weigel PH (eds). Amsterdam: Elsevier Science
-
Singh M, Briones M, O'Hagan D. Hyaluronic acid biopolymers for mucosal delivery of vaccines. In: Abatangelo G, Weigel PH (eds) New Frontiers in Medical Sciences: Redefining hyaluronan. Amsterdam: Elsevier Science, 2000; 163-70.
-
(2000)
New Frontiers in Medical Sciences: Redefining Hyaluronan
, pp. 163-170
-
-
Singh, M.1
Briones, M.2
O'Hagan, D.3
-
13
-
-
0035863580
-
Potency of a genetically detoxified mucosal adjuvant derived from the heat-labile enterotoxin of Escherichia coli (LTK63) is not adversely affected by the presence of preexisting immunity to the adjuvant
-
Ugozzoli M, Santos G, Donnelly J, O'Hagan DT. Potency of a genetically detoxified mucosal adjuvant derived from the heat-labile enterotoxin of Escherichia coli (LTK63) is not adversely affected by the presence of preexisting immunity to the adjuvant. J. Infect. Dis. 2001; 183: 351-4.
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 351-354
-
-
Ugozzoli, M.1
Santos, G.2
Donnelly, J.3
O'Hagan, D.T.4
-
14
-
-
1642432002
-
From toxin to adjuvant: The rational design of a vaccine adjuvant vector, CTA1-DD/ISCOM
-
Lycke N. From toxin to adjuvant: the rational design of a vaccine adjuvant vector, CTA1-DD/ISCOM. Cell. Microbiol. 2004; 6: 23-32.
-
(2004)
Cell. Microbiol.
, vol.6
, pp. 23-32
-
-
Lycke, N.1
-
15
-
-
0026703432
-
Bacterial cell wall products as adjuvants: Early interferon gamma as a marker for adjuvants that enhance protective immunity
-
Gustafson GL, Rhodes MJ. Bacterial cell wall products as adjuvants: early interferon gamma as a marker for adjuvants that enhance protective immunity. Res. Immunol. 1992; 143: 483-8.
-
(1992)
Res. Immunol.
, vol.143
, pp. 483-488
-
-
Gustafson, G.L.1
Rhodes, M.J.2
-
16
-
-
0029201182
-
Monophosphoryl lipid a as an adjuvant: Past experiences and new directions
-
Ulrich JT, Myers KR. Monophosphoryl lipid A as an adjuvant: Past experiences and new directions. Pharm. Biotechnol. 1995; 6: 495-524.
-
(1995)
Pharm. Biotechnol.
, vol.6
, pp. 495-524
-
-
Ulrich, J.T.1
Myers, K.R.2
-
17
-
-
0000775735
-
MPLr immunostimulant: Adjuvant formulations
-
O'Hagan DT (ed.). Totowa, NJ: Humana Press
-
Ulrich JT. MPLr immunostimulant: adjuvant formulations. In: O'Hagan DT (ed.) Vaccine Adjuvants: Preparation Methods and Research Protocols. Totowa, NJ: Humana Press, 2000; 273-82.
-
(2000)
Vaccine Adjuvants: Preparation Methods and Research Protocols
, pp. 273-282
-
-
Ulrich, J.T.1
-
18
-
-
0035208015
-
A Th1-indueing adjuvant, MPL, enhances antibody profiles in experimental animals suggesting it has the potential to improve the efficacy of allergy vaccines
-
Wheeler AW, Marshall JS, Ulrich JT. A Th1-indueing adjuvant, MPL, enhances antibody profiles in experimental animals suggesting it has the potential to improve the efficacy of allergy vaccines. Int. Arch. Allergy Immunol. 2001; 126: 135-9.
-
(2001)
Int. Arch. Allergy Immunol.
, vol.126
, pp. 135-139
-
-
Wheeler, A.W.1
Marshall, J.S.2
Ulrich, J.T.3
-
19
-
-
0033805905
-
Adjuvant activity of monophosphoryl lipid a for nasal and oral immunization with soluble or liposome-associated antigen
-
Childers NK, Miller KL, Tong G et al. Adjuvant activity of monophosphoryl lipid A for nasal and oral immunization with soluble or liposome-associated antigen. Infect. Immun. 2000; 68: 5509-516.
-
(2000)
Infect. Immun.
, vol.68
, pp. 5509-5516
-
-
Childers, N.K.1
Miller, K.L.2
Tong, G.3
-
20
-
-
2142704355
-
Intranasal immunization with multivalent group a streptococcal vaccines protects mice against intranasal challenge infections
-
Hall MA, Stroop SD, Hu MC et al. Intranasal immunization with multivalent group A streptococcal vaccines protects mice against intranasal challenge infections. Infect. Immun. 2004; 72: 2507-512.
-
(2004)
Infect. Immun.
, vol.72
, pp. 2507-2512
-
-
Ma, H.1
Stroop, S.D.2
Hu, M.C.3
-
21
-
-
0032519965
-
HIV-1 neutralizing antibodies in the genital and respiratory tracts of mice intranasally immunized with oligomeric gp160
-
VanCott TC, Kaminski RW, Mascola JR et al. HIV-1 neutralizing antibodies in the genital and respiratory tracts of mice intranasally immunized with oligomeric gp160. J. Immunol. 1998; 160: 2000-2012.
-
(1998)
J. Immunol.
, vol.160
, pp. 2000-2012
-
-
VanCott, T.C.1
Kaminski, R.W.2
Mascola, J.R.3
-
22
-
-
0026006734
-
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
-
Messina JP, Gilkeson GS, Pisetsky DS. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J. Immunol. 1991; 147: 1759-64.
-
(1991)
J. Immunol.
, vol.147
, pp. 1759-1764
-
-
Messina, J.P.1
Gilkeson, G.S.2
Pisetsky, D.S.3
-
23
-
-
0021256125
-
Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity
-
Tokunaga T, Yamamoto H, Shimada S et al. Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity. J. Natl Cancer Inst. 1984; 72: 955-62.
-
(1984)
J. Natl Cancer Inst.
, vol.72
, pp. 955-962
-
-
Tokunaga, T.1
Yamamoto, H.2
Shimada, S.3
-
24
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg AM, Yi AK, Matson S et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995; 374: 6546-9.
-
(1995)
Nature
, vol.374
, pp. 6546-6549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
-
25
-
-
0023472826
-
CpG islands as gene markers in the vertebrate nucleus
-
Bird AP. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 1987; 3: 342-7.
-
(1987)
Trends Genet.
, vol.3
, pp. 342-347
-
-
Bird, A.P.1
-
26
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740-45.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
27
-
-
0031867535
-
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
-
Sparwasser T, Koch ES, Vabulas RM et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 1998; 28: 2045-54.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2045-2054
-
-
Sparwasser, T.1
Koch, E.S.2
Vabulas, R.M.3
-
29
-
-
0032534602
-
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
-
Broide D, Schwarze J, Tighe H et al. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J. Immunol. 1998; 161: 7054-62.
-
(1998)
J. Immunol.
, vol.161
, pp. 7054-7062
-
-
Broide, D.1
Schwarze, J.2
Tighe, H.3
-
30
-
-
2942516628
-
Modulating vaccine responses with dendritic cells and Toll-like receptors
-
Pulendran B. Modulating vaccine responses with dendritic cells and Toll-like receptors. Immunol. Rev. 2004; 199: 227-50.
-
(2004)
Immunol. Rev.
, vol.199
, pp. 227-250
-
-
Pulendran, B.1
-
31
-
-
0038325751
-
Mucosal immunization and adjuvants: A brief overview of recent advances and challenges
-
Holmgren J, Czerkinsky C, Eriksson K, Mharandi A. Mucosal immunization and adjuvants: a brief overview of recent advances and challenges. Vaccine 2003; 21 (Suppl 2): S89-95.
-
(2003)
Vaccine
, vol.21
, Issue.SUPPL. 2
-
-
Holmgren, J.1
Czerkinsky, C.2
Eriksson, K.3
Mharandi, A.4
-
32
-
-
0141886316
-
Immunization with Th-CTL fusion peptide and cytosine-phosphate-guanine DNA in transgenic HLA-A2 mice induces recognition of HIV-infected T cells and clears vaccinia virus challenge
-
Daftarian P, Ali S, Sharan R et al. Immunization with Th-CTL fusion peptide and cytosine-phosphate-guanine DNA in transgenic HLA-A2 mice induces recognition of HIV-infected T cells and clears vaccinia virus challenge. J. Immunol. 2003; 171: 4028-39.
-
(2003)
J. Immunol.
, vol.171
, pp. 4028-4039
-
-
Daftarian, P.1
Ali, S.2
Sharan, R.3
-
33
-
-
0037108812
-
Mucosal immunization with inactivated human immunodeficiency virus plus CpG oligodeoxynucleotides induces genital immune responses and protection against intravaginal challenge
-
Dumais N, Patrick A, Moss RB, Davis HL, Rosenthal KL. Mucosal immunization with inactivated human immunodeficiency virus plus CpG oligodeoxynucleotides induces genital immune responses and protection against intravaginal challenge. J. Infect. Dis. 2002; 186: 1098-105.
-
(2002)
J. Infect. Dis.
, vol.186
, pp. 1098-1105
-
-
Dumais, N.1
Patrick, A.2
Moss, R.B.3
Davis, H.L.4
Rosenthal, K.L.5
-
36
-
-
37049052069
-
Action of saponins on biological membranes
-
Glaueri AM, Dingle JT, Lucy JA. Action of saponins on biological membranes. Nature 1962; 196: 953.
-
(1962)
Nature
, vol.196
, pp. 953
-
-
Glaueri, A.M.1
Dingle, J.T.2
Lucy, J.A.3
-
37
-
-
0031661414
-
QS-21 : A water-soluble triterpene glycoside adjuvant
-
Kensil CR, Kammer R. QS-21 : a water-soluble triterpene glycoside adjuvant. Exp. Opin. Invest. Drugs 1998; 7: 1475-82.
-
(1998)
Exp. Opin. Invest. Drugs
, vol.7
, pp. 1475-1482
-
-
Kensil, C.R.1
Kammer, R.2
-
38
-
-
0035865385
-
Oral QS-21 requires early IL-4 help for induction of mucosal and systemic immunity
-
Boyaka PN, Marinaro M, Jackson RJ et al. Oral QS-21 requires early IL-4 help for induction of mucosal and systemic immunity. J. Immunol. 2001; 166: 2283-90.
-
(2001)
J. Immunol.
, vol.166
, pp. 2283-2290
-
-
Boyaka, P.N.1
Marinaro, M.2
Jackson, R.J.3
-
39
-
-
0031926264
-
Induction of systemic and mucosal immune responses to human immunodeficiency virus type 1 by a DNA vaccine formulated with QS-21 saponin adjuvant via intramuscular and intranasal routes
-
Sasaki S, Sumino K, Hamajima K et al. Induction of systemic and mucosal immune responses to human immunodeficiency virus type 1 by a DNA vaccine formulated with QS-21 saponin adjuvant via intramuscular and intranasal routes. J. Virol. 1998; 72: 4931-9.
-
(1998)
J. Virol.
, vol.72
, pp. 4931-4939
-
-
Sasaki, S.1
Sumino, K.2
Hamajima, K.3
-
40
-
-
0029177445
-
Cytokines as immunological adjuvants
-
Heath AW. Cytokines as immunological adjuvants. Pharm. Biotechnol. 1995; 6: 645-58.
-
(1995)
Pharm. Biotechnol.
, vol.6
, pp. 645-658
-
-
Heath, A.W.1
-
41
-
-
0031863732
-
Use of cellular and cytokine adjuvants in the immunotherapy of cancer
-
Salgaller ML, Lodge PA. Use of cellular and cytokine adjuvants in the immunotherapy of cancer. J. Surg. Oncol. 1998; 68: 122-38.
-
(1998)
J. Surg. Oncol.
, vol.68
, pp. 122-138
-
-
Salgaller, M.L.1
Lodge, P.A.2
-
42
-
-
0030784824
-
Characterization of poly (glycolide-co-D,1-lactide)/poly (D,1-lactide) microspheres for controlled release of GM-CSF
-
Pettit DK, Lawter JR, Huang WJ et al. Characterization of poly (glycolide-co-D,1-lactide)/poly (D,1-lactide) microspheres for controlled release of GM-CSF. Pharm. Res. 1997; 14: 1422-30.
-
(1997)
Pharm. Res.
, vol.14
, pp. 1422-1430
-
-
Pettit, D.K.1
Lawter, J.R.2
Huang, W.J.3
-
43
-
-
0034660885
-
In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: Induction of tumor regression and potent antitumor immunity
-
Egilmez NK, Jong YS, Sabel MS, Jacob JS, Mathiowitz E, Bankert RB. In situ tumor vaccination with interleukin-12-encapsulated biodegradable microspheres: induction of tumor regression and potent antitumor immunity. Cancer Res. 2000; 60: 3832-7.
-
(2000)
Cancer Res.
, vol.60
, pp. 3832-3837
-
-
Egilmez, N.K.1
Jong, Y.S.2
Sabel, M.S.3
Jacob, J.S.4
Mathiowitz, E.5
Bankert, R.B.6
-
44
-
-
0043180521
-
Therapeutic manipulation of the immune system: Enhancement of innate and adaptive mucosal immunity
-
Boyaka PN, Tafaro A, Fischer R, Fujihashi K, Jirillo E, McGhee JR. Therapeutic manipulation of the immune system: enhancement of innate and adaptive mucosal immunity. Curr. Pharm. Des. 2003; 9: 1965-72.
-
(2003)
Curr. Pharm. Des.
, vol.9
, pp. 1965-1972
-
-
Boyaka, P.N.1
Tafaro, A.2
Fischer, R.3
Fujihashi, K.4
Jirillo, E.5
McGhee, J.R.6
-
45
-
-
0043246700
-
Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12
-
Lynch JM, Briles DE, Metzger DW. Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12. Infect. Immun. 2003; 71: 4780-8.
-
(2003)
Infect. Immun.
, vol.71
, pp. 4780-4788
-
-
Lynch, J.M.1
Briles, D.E.2
Metzger, D.W.3
-
46
-
-
0036140236
-
Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization
-
Bradney CP, Sempowski GD, Liao HX, Haynes BF, Staats HF. Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization. J. Virol. 2002; 76: 517-24.
-
(2002)
J. Virol.
, vol.76
, pp. 517-524
-
-
Bradney, C.P.1
Sempowski, G.D.2
Liao, H.X.3
Haynes, B.F.4
Staats, H.F.5
-
47
-
-
0035500640
-
Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization
-
Staats HF, Bradney CP, Gwinn WM et al. Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization. J. Immunol. 2001; 167: 5386-94.
-
(2001)
J. Immunol.
, vol.167
, pp. 5386-5394
-
-
Staats, H.F.1
Bradney, C.P.2
Gwinn, W.M.3
-
48
-
-
0038054534
-
Influence of DNA encoding cytokines on systemic and mucosal immunity following genetic vaccination against herpes simplex virus
-
Lee S, Gierynska M, Eo SK, Kuklin N, Rouse BT. Influence of DNA encoding cytokines on systemic and mucosal immunity following genetic vaccination against herpes simplex virus. Microbes Infect. 2003; 5: 571-8.
-
(2003)
Microbes Infect.
, vol.5
, pp. 571-578
-
-
Lee, S.1
Gierynska, M.2
Eo, S.K.3
Kuklin, N.4
Rouse, B.T.5
-
50
-
-
2642677624
-
Improving protein therapeutics with sustained-release formulations
-
Putney SD, Burke PA. Improving protein therapeutics with sustained-release formulations. (Published erratum appears in Nat Biotechnol. 1998; 16: 478.) Nat. Biotechnol. 1998; 16: 153-7.
-
(1998)
Nat. Biotechnol.
, vol.16
-
-
Putney, S.D.1
Burke, P.A.2
-
51
-
-
0031922193
-
-
Published erratum appears
-
Putney SD, Burke PA. Improving protein therapeutics with sustained-release formulations. (Published erratum appears in Nat Biotechnol. 1998; 16: 478.) Nat. Biotechnol. 1998; 16: 153-7.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 478
-
-
-
52
-
-
0025834747
-
Biodegradable and biocompatible poly (DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies
-
Eldridge JH, Staas JK, Meulbroek JA, Tice TR, Gilley RM. Biodegradable and biocompatible poly (DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect. Immunol. 1991; 59: 2978-86.
-
(1991)
Infect. Immunol.
, vol.59
, pp. 2978-2986
-
-
Eldridge, J.H.1
Staas, J.K.2
Meulbroek, J.A.3
Tice, T.R.4
Gilley, R.M.5
-
53
-
-
0025730382
-
Biodegradable microparticles as controlled release antigen delivery systems
-
O'Hagan DT, Rahman D, McGee JP et al. Biodegradable microparticles as controlled release antigen delivery systems. Immunol. 1991; 73: 239-42.
-
(1991)
Immunol.
, vol.73
, pp. 239-242
-
-
O'Hagan, D.T.1
Rahman, D.2
McGee, J.P.3
-
54
-
-
0025899254
-
Controlled release microparticles for vaccine development
-
O'Hagan DT, Jeffery H, Roberts MJ, McGee JP, Davis SS. Controlled release microparticles for vaccine development. Vaccine 1991; 9: 768-71.
-
(1991)
Vaccine
, vol.9
, pp. 768-771
-
-
O'Hagan, D.T.1
Jeffery, H.2
Roberts, M.J.3
McGee, J.P.4
Davis, S.S.5
-
55
-
-
0027305289
-
Long-term antibody responses in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles
-
O'Hagan DT, Jeffery H, Davis SS. Long-term antibody responses in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles. Vaccine 1993; 11: 965-9.
-
(1993)
Vaccine
, vol.11
, pp. 965-969
-
-
O'Hagan, D.T.1
Jeffery, H.2
Davis, S.S.3
-
56
-
-
0028049676
-
Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly (lactide-co-glycolide) microparticles
-
Maloy KJ, Donachie AM, O'Hagan DT, Mowat AM. Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly (lactide-co-glycolide) microparticles. Immunology 1994; 81: 661-7.
-
(1994)
Immunology
, vol.81
, pp. 661-667
-
-
Maloy, K.J.1
Donachie, A.M.2
O'Hagan, D.T.3
Mowat, A.M.4
-
57
-
-
0029558085
-
Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells
-
Moore A, McGuirk P, Adams S et al. Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells. Vaccine 1995; 13: 1741-9.
-
(1995)
Vaccine
, vol.13
, pp. 1741-1749
-
-
Moore, A.1
McGuirk, P.2
Adams, S.3
-
58
-
-
0001552479
-
Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity
-
Nixon DF, Hioe C, Chen PD et al. Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity. Vaccine 1996; 14: 1523-30.
-
(1996)
Vaccine
, vol.14
, pp. 1523-1530
-
-
Nixon, D.F.1
Hioe, C.2
Chen, P.D.3
-
59
-
-
0021020950
-
Interaction of microspheres with blood constituents. I. Uptake of polystyrene spheres by monocytes and granulocytes and effect on immune responsiveness of lymphocytes
-
Kanke M, Sniecinski I, DeLuca PP. Interaction of microspheres with blood constituents. I. Uptake of polystyrene spheres by monocytes and granulocytes and effect on immune responsiveness of lymphocytes. J. Parenter. Sci. Technol. 1983; 37: 210-17.
-
(1983)
J. Parenter. Sci. Technol.
, vol.37
, pp. 210-217
-
-
Kanke, M.1
Sniecinski, I.2
DeLuca, P.P.3
-
60
-
-
0024094796
-
Macrophage phagocytosis of biodegradable microspheres composed of 1-lactic acid/glycolic acid homo- and copolymers
-
Tabata Y, Ikada Y. Macrophage phagocytosis of biodegradable microspheres composed of 1-lactic acid/glycolic acid homo- and copolymers. J. Biomed. Mater. Res. 1988; 22: 837-58.
-
(1988)
J. Biomed. Mater. Res.
, vol.22
, pp. 837-858
-
-
Tabata, Y.1
Ikada, Y.2
-
61
-
-
0342424906
-
Phagocytosis of polymer microspheres by macrophages
-
Tabata Y, Ikada Y. Phagocytosis of polymer microspheres by macrophages. Adv. Polymer Sci. 1990; 94: 107-41.
-
(1990)
Adv. Polymer Sci.
, vol.94
, pp. 107-141
-
-
Tabata, Y.1
Ikada, Y.2
-
62
-
-
0033403066
-
Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
-
Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity 1999; 11: 753-61.
-
(1999)
Immunity
, vol.11
, pp. 753-761
-
-
Randolph, G.J.1
Inaba, K.2
Robbiani, D.F.3
Steinman, R.M.4
Muller, W.A.5
-
63
-
-
0036805438
-
Analysis of poly (D,1-lactic-co-glycolic acid) nanosphere uptake by human dendritic cells and macrophages in vitro
-
Lutsiak ME, Robinson DR, Coester C, Kwon GS, Samuel J. Analysis of poly (D,1-lactic-co-glycolic acid) nanosphere uptake by human dendritic cells and macrophages in vitro. Pharm. Res. 2002; 19: 1480-87.
-
(2002)
Pharm. Res.
, vol.19
, pp. 1480-1487
-
-
Lutsiak, M.E.1
Robinson, D.R.2
Coester, C.3
Kwon, G.S.4
Samuel, J.5
-
64
-
-
0037024108
-
Uptake of poly (D,1-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo
-
Newman KD, Elamanchili P, Kwon GS, Samuel J. Uptake of poly (D,1-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo. J. Biomed. Mater. Res. 2002; 60: 480-86.
-
(2002)
J. Biomed. Mater. Res.
, vol.60
, pp. 480-486
-
-
Newman, K.D.1
Elamanchili, P.2
Kwon, G.S.3
Samuel, J.4
-
65
-
-
0034601242
-
Novel anionic microparticles are a potent adjuvant for the induction of cytotoxic T lymphocytes against recombinant p55 gag from HIV-1
-
Kazzaz J, Neidleman J, Singh M, Ott G, O'Hagan DT. Novel anionic microparticles are a potent adjuvant for the induction of cytotoxic T lymphocytes against recombinant p55 gag from HIV-1. J. Control. Release 2000; 67: 347-56.
-
(2000)
J. Control. Release
, vol.67
, pp. 347-356
-
-
Kazzaz, J.1
Neidleman, J.2
Singh, M.3
Ott, G.4
O'Hagan, D.T.5
-
66
-
-
0034950338
-
Tetanus toxoid loaded nanoparticles from sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide): Evaluation of antibody response after oral and nasal application in mice
-
Jung T, Kamm W, Breitenbach A, Hungerer KD, Hundt E, Kissel T. Tetanus toxoid loaded nanoparticles from sulfobutylated poly(vinyl alcohol)-graft- poly(lactide-co-glycolide): evaluation of antibody response after oral and nasal application in mice. Pharm. Res. 2001; 18: 352-60.
-
(2001)
Pharm. Res.
, vol.18
, pp. 352-360
-
-
Jung, T.1
Kamm, W.2
Breitenbach, A.3
Hungerer, K.D.4
Hundt, E.5
Kissel, T.6
-
67
-
-
0031888227
-
Intranasal immunization with polymer-grafted microparticles activates the nasal-associated lymphoid tissue and draining lymph nodes
-
Heritage PL, Brook MA, Underdown BJ, McDermott MR. Intranasal immunization with polymer-grafted microparticles activates the nasal-associated lymphoid tissue and draining lymph nodes. Immunology 1998; 93: 249-56.
-
(1998)
Immunology
, vol.93
, pp. 249-256
-
-
Heritage, P.L.1
Brook, M.A.2
Underdown, B.J.3
McDermott, M.R.4
-
68
-
-
0031842330
-
Polymer-grafted starch microparticles for oral and nasal immunization. Immunol
-
McDermott MR, Heritage PL, Bartzoka V, Brook MA. Polymer-grafted starch microparticles for oral and nasal immunization. Immunol. Cell Biol. 1998; 76: 256-62.
-
(1998)
Cell Biol.
, vol.76
, pp. 256-262
-
-
McDermott, M.R.1
Heritage, P.L.2
Bartzoka, V.3
Brook, M.A.4
-
69
-
-
0032921895
-
Single-dose mucosal immunization with biodegradable microparticles containing a Schistosoma mansoni antigen
-
Baras B, Benoit MA, Dupre L et al. Single-dose mucosal immunization with biodegradable microparticles containing a Schistosoma mansoni antigen. Infect. Immun. 1999; 67: 2643-8.
-
(1999)
Infect. Immun.
, vol.67
, pp. 2643-2648
-
-
Baras, B.1
Benoit, M.A.2
Dupre, L.3
-
70
-
-
0032053613
-
Enhancement of immune response to intranasal influenza HA vaccine by microparticle resin
-
Higaki M, Takase T, Igarashi R et al. Enhancement of immune response to intranasal influenza HA vaccine by microparticle resin. Vaccine 1998; 16: 741-5.
-
(1998)
Vaccine
, vol.16
, pp. 741-745
-
-
Higaki, M.1
Takase, T.2
Igarashi, R.3
-
71
-
-
0037073666
-
Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres
-
Kim B, Bowersock T, Griebel P et al. Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres. J. Control. Release 2002; 85: 191-202.
-
(2002)
J. Control. Release
, vol.85
, pp. 191-202
-
-
Kim, B.1
Bowersock, T.2
Griebel, P.3
-
72
-
-
0022854034
-
An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity
-
Allison AC, Byars NE. An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity. J. Immunol. Meth. 1986; 95: 157-68.
-
(1986)
J. Immunol. Meth.
, vol.95
, pp. 157-168
-
-
Allison, A.C.1
Byars, N.E.2
-
74
-
-
0002767893
-
Adjuvants for the future
-
Levine MM, Woodrow GC, Kaper JB, Cobon GS (eds). New York: Marcel Dekker
-
Edelman R. Adjuvants for the future. In: Levine MM, Woodrow GC, Kaper JB, Cobon GS (eds) New Generation Vaccines. New York: Marcel Dekker, 1997; 173-92.
-
(1997)
New Generation Vaccines
, pp. 173-192
-
-
Edelman, R.1
-
75
-
-
0029177443
-
MF59. Design and evaluation of a safe and potent adjuvant for human vaccines
-
Powell MF, Newman MJ (eds). New York: Plenum Press
-
Ott G, Barchfeld GL, Chernoff D et al. MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. In: Powell MF, Newman MJ (eds) Vaccine Design: The Subunit and Adjuvant Approach. New York: Plenum Press, 1995; 277-96.
-
(1995)
Vaccine Design: The Subunit and Adjuvant Approach
, pp. 277-296
-
-
Ott, G.1
Barchfeld, G.L.2
Chernoff, D.3
-
76
-
-
0030880922
-
The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice
-
Cataldo DM, Van Nest G. The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. Vaccine 1997; 15: 1710-15.
-
(1997)
Vaccine
, vol.15
, pp. 1710-1715
-
-
Cataldo, D.M.1
Van Nest, G.2
-
77
-
-
0030012890
-
MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice
-
Higgins DA, Carlson JR, Van Nest G. MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice. Vaccine 1996; 14: 478-84.
-
(1996)
Vaccine
, vol.14
, pp. 478-484
-
-
Higgins, D.A.1
Carlson, J.R.2
Van Nest, G.3
-
78
-
-
0031062313
-
Recent advances in vaccine adjuvants: The development of MF59 emulsion and polymeric microparticles
-
O'Hagan DT, Ott GS, Van Nest G. Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. Mol. Med. Today 1997; 3: 69-75.
-
(1997)
Mol. Med. Today
, vol.3
, pp. 69-75
-
-
O'Hagan, D.T.1
Ott, G.S.2
Van Nest, G.3
-
79
-
-
0029852624
-
MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates
-
Traquina P, Morandi M, Contorni M, Van Nest G. MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates. J. Infect. Dis. 1996; 174: 1168-75.
-
(1996)
J. Infect. Dis.
, vol.174
, pp. 1168-1175
-
-
Traquina, P.1
Morandi, M.2
Contorni, M.3
Van Nest, G.4
-
80
-
-
0033575487
-
A randomized, controlled study in adults of the immunogenicity of a novel hepatitis B vaccine containing MF59 adjuvant
-
Heineman TC, Clements-Mann ML, Poland GA et al. A randomized, controlled study in adults of the immunogenicity of a novel hepatitis B vaccine containing MF59 adjuvant. Vaccine 1999; 17: 2769-78.
-
(1999)
Vaccine
, vol.17
, pp. 2769-2778
-
-
Heineman, T.C.1
Clements-Mann, M.L.2
Poland, G.A.3
-
81
-
-
0032804298
-
Influenza vaccines: Antibody responses to split virus and MF59-adjuvanted subunit virus in an adult population
-
Menegon T, Baldo V, Bonello C, Dalla CD, Di Tommaso A, Trivello R. Influenza vaccines: antibody responses to split virus and MF59-adjuvanted subunit virus in an adult population. Eur. J. Epidemiol. 1999; 15: 573-6.
-
(1999)
Eur. J. Epidemiol.
, vol.15
, pp. 573-576
-
-
Menegon, T.1
Baldo, V.2
Bonello, C.3
Dalla, C.D.4
Di Tommaso, A.5
Trivello, R.6
-
82
-
-
0033529516
-
Safety and immunogenicity of MF59-adjuvanted influenza vaccine in the elderly
-
De Donato S, Granoff D, Minutello M et al. Safety and immunogenicity of MF59-adjuvanted influenza vaccine in the elderly. Vaccine 1999; 17: 3094-101.
-
(1999)
Vaccine
, vol.17
, pp. 3094-3101
-
-
De Donato, S.1
Granoff, D.2
Minutello, M.3
-
83
-
-
0026473039
-
Immunologic aspects of liposomes: Presentation and processing of liposomal protein and phospholipid antigens
-
Alving CR. Immunologic aspects of liposomes: presentation and processing of liposomal protein and phospholipid antigens. Biochim. Biophys. Acta 1992; 1113: 307-22.
-
(1992)
Biochim. Biophys. Acta
, vol.1113
, pp. 307-322
-
-
Alving, C.R.1
-
84
-
-
0025129271
-
Immunological adjuvants: A role for liposomes
-
Gregoriadis G. Immunological adjuvants: a role for liposomes. Immunol. Today 1990; 11: 89-97.
-
(1990)
Immunol. Today
, vol.11
, pp. 89-97
-
-
Gregoriadis, G.1
-
85
-
-
0030819524
-
Immunogenicity and protectivity of a new liposomal hepatitis A vaccine
-
Ambrosch F, Wiedermann G, Jonas S et al. Immunogenicity and protectivity of a new liposomal hepatitis A vaccine. Vaccine 1997; 15: 1209-13.
-
(1997)
Vaccine
, vol.15
, pp. 1209-1213
-
-
Ambrosch, F.1
Wiedermann, G.2
Jonas, S.3
-
88
-
-
0033526828
-
Augmentation of human influenza a virus-specific cytotoxic T lymphocyte memory by influenza vaccine and adjuvanted carriers (ISCOMs)
-
Ennis FA, Cruz J, Jameson J, Klein M, Burt D, Thipphawong J. Augmentation of human influenza A virus-specific cytotoxic T lymphocyte memory by influenza vaccine and adjuvanted carriers (ISCOMs). Virology 1999; 259: 256-61.
-
(1999)
Virology
, vol.259
, pp. 256-261
-
-
Ennis, F.A.1
Cruz, J.2
Jameson, J.3
Klein, M.4
Burt, D.5
Thipphawong, J.6
-
89
-
-
0028800377
-
Structure/function studies of QS-21 adjuvant: Assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function
-
Soltysik S, Wu JY, Recchia J et al. Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function. Vaccine 1995; 13: 1403-10.
-
(1995)
Vaccine
, vol.13
, pp. 1403-1410
-
-
Soltysik, S.1
Wu, J.Y.2
Recchia, J.3
-
92
-
-
0029051152
-
Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus
-
Donnelly JJ, Friedman A, Martinez D et al. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus. Nat. Med. 1995; 1: 583-7.
-
(1995)
Nat. Med.
, vol.1
, pp. 583-587
-
-
Donnelly, J.J.1
Friedman, A.2
Martinez, D.3
-
93
-
-
0032538597
-
Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
-
Wang R, Doolan DL, Le TP et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 1998; 282: 476-80.
-
(1998)
Science
, vol.282
, pp. 476-480
-
-
Wang, R.1
Doolan, D.L.2
Le, T.P.3
-
94
-
-
0034703836
-
Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine
-
Roy MJ, Wu MS, Barr LJ et al. Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine. Vaccine 2000; 19: 764-78.
-
(2000)
Vaccine
, vol.19
, pp. 764-778
-
-
Roy, M.J.1
Wu, M.S.2
Barr, L.J.3
-
95
-
-
0030111265
-
Codon usage limitation in the expression of HIV-1 envelope glycoprotein
-
Haas J, Park E, Seed B. Codon usage limitation in the expression of HIV-1 envelope glycoprotein. Curr. Biol. 1996; 6: 315-24.
-
(1996)
Curr. Biol.
, vol.6
, pp. 315-324
-
-
Haas, J.1
Park, E.2
Seed, B.3
-
96
-
-
0034056240
-
Increased expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 gag gene
-
zur Megede J, Chen MC, Doe B et al. Increased expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 gag gene. J. Virol. 2000; 74: 2628-35.
-
(2000)
J. Virol.
, vol.74
, pp. 2628-2635
-
-
Zur Megede, J.1
Chen, M.C.2
Doe, B.3
-
97
-
-
0031906148
-
Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage
-
Andre S, Seed B, Eberle J, Schraut W, Bultmann A, Haas J. Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage. J. Virol. 1998; 72: 1497-503.
-
(1998)
J. Virol.
, vol.72
, pp. 1497-1503
-
-
Andre, S.1
Seed, B.2
Eberle, J.3
Schraut, W.4
Bultmann, A.5
Haas, J.6
-
98
-
-
0032533471
-
Optimization of codon usage of plasmid DNA vaccine is required for the effective MHC class I-restricted T cell responses against an intracellular bacterium
-
Uchijima M, Yoshida A, Nagata T, Koide Y. Optimization of codon usage of plasmid DNA vaccine is required for the effective MHC class I-restricted T cell responses against an intracellular bacterium. J. Immunol. 1998; 161: 5594-9.
-
(1998)
J. Immunol.
, vol.161
, pp. 5594-5599
-
-
Uchijima, M.1
Yoshida, A.2
Nagata, T.3
Koide, Y.4
-
99
-
-
0031838647
-
Enhancing immune responses using suicidal DNA vaccines
-
Berglund P, Smerdou C, Fleeton MN, Tubulekas I, Liljestrom P. Enhancing immune responses using suicidal DNA vaccines. Nat. Biotechnol. 1998; 16: 562-5.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 562-565
-
-
Berglund, P.1
Smerdou, C.2
Fleeton, M.N.3
Tubulekas, I.4
Liljestrom, P.5
-
100
-
-
0031882102
-
DNA immunization against herpes simplex virus: Enhanced efficacy using a Sindbis virus-based vector
-
Hariharan MJ, Driver DA, Townsend K. et al DNA immunization against herpes simplex virus: enhanced efficacy using a Sindbis virus-based vector. J. Virol. 1998; 72: 950-58.
-
(1998)
J. Virol.
, vol.72
, pp. 950-958
-
-
Hariharan, M.J.1
Driver, D.A.2
Townsend, K.3
-
101
-
-
0031775363
-
The search for a potent DNA vaccine against AIDS: The enhancement of immunogenicity by chemical and genetic adjuvants
-
Sasaki S, Tsuki T, Asakura Y, Fukushima J, Okuda K. The search for a potent DNA vaccine against AIDS: the enhancement of immunogenicity by chemical and genetic adjuvants. Anticancer Res. 1998; 18: 3907-16.
-
(1998)
Anticancer Res.
, vol.18
, pp. 3907-3916
-
-
Sasaki, S.1
Tsuki, T.2
Asakura, Y.3
Fukushima, J.4
Okuda, K.5
-
102
-
-
0033588543
-
Enhancement of DNA vaccine potency using conventional aluminum adjuvants
-
Ulmer JB, DeWitt CM, Chastain M et al. Enhancement of DNA vaccine potency using conventional aluminum adjuvants. Vaccine 1999; 18: 18-28.
-
(1999)
Vaccine
, vol.18
, pp. 18-28
-
-
Ulmer, J.B.1
DeWitt, C.M.2
Chastain, M.3
-
103
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff JA, Malone RW, Williams P et al. Direct gene transfer into mouse muscle in vivo. Science 1990; 247: 1465-8.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
-
105
-
-
0032526344
-
Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/ antigen-presenting cells
-
Chattergoon MA, Robinson TM, Boyer JD, Weiner DB. Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/ antigen-presenting cells. J. Immunol. 1998; 160: 5707-18.
-
(1998)
J. Immunol.
, vol.160
, pp. 5707-5718
-
-
Chattergoon, M.A.1
Robinson, T.M.2
Boyer, J.D.3
Weiner, D.B.4
-
106
-
-
17744380618
-
Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells
-
Denis-Mize KS, Dupuis M, MacKichan ML et al. Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells. Gene Ther. 2000; 7: 2105-12.
-
(2000)
Gene Ther.
, vol.7
, pp. 2105-2112
-
-
Denis-Mize, K.S.1
Dupuis, M.2
MacKichan, M.L.3
-
107
-
-
0033521543
-
DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
-
Akbari O, Panjwani N, Garcia S, Tascon R, Lowrie D, Stockinger B. DNA vaccination: transfection and activation of dendritic cells as key events for immunity. J. Exp. Med. 1999; 189: 169-78.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 169-178
-
-
Akbari, O.1
Panjwani, N.2
Garcia, S.3
Tascon, R.4
Lowrie, D.5
Stockinger, B.6
-
108
-
-
0032990254
-
Immunization through dermal delivery of protein-encoding DNA: A role for migratory dendritic cells
-
Bouloc A, Walker P, Grivel JC, Vogel JC, Katz SI. Immunization through dermal delivery of protein-encoding DNA: a role for migratory dendritic cells. Eur. J. Immunol. 1999; 29: 446-54.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 446-454
-
-
Bouloc, A.1
Walker, P.2
Grivel, J.C.3
Vogel, J.C.4
Katz, S.I.5
-
109
-
-
0032565591
-
Dendritic cells internalize vaccine adjuvant after intramuscular injection
-
Dupuis M, Murphy TJ, Higgins D et al. Dendritic cells internalize vaccine adjuvant after intramuscular injection. Cell. Immunol. 1998; 186: 18-27.
-
(1998)
Cell. Immunol.
, vol.186
, pp. 18-27
-
-
Dupuis, M.1
Murphy, T.J.2
Higgins, D.3
-
110
-
-
0031915963
-
Microspheres containing plasmid-encoded antigens elicit cytotoxic T-cell responses
-
Hedley ML, Curley J, Urban R. Microspheres containing plasmid-encoded antigens elicit cytotoxic T-cell responses. Nat. Med. 1998; 4: 365-8.
-
(1998)
Nat. Med.
, vol.4
, pp. 365-368
-
-
Hedley, M.L.1
Curley, J.2
Urban, R.3
-
113
-
-
0032949618
-
PLGA microspheres containing plasmid DNA: Preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization
-
Ando S, Putnam D, Pack DW, Langer R. PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization. J. Pharm. Sci. 1999; 88: 126-30.
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 126-130
-
-
Ando, S.1
Putnam, D.2
Pack, D.W.3
Langer, R.4
-
114
-
-
0034657718
-
Formulation of poly (D,1-lactic-co-glycolic acid) microparticles for rapid plasmid DNA delivery
-
Tinsley-Bown AM, Fretwell R, Dowsett AB, Davis SL, Farrar GH. Formulation of poly (D,1-lactic-co-glycolic acid) microparticles for rapid plasmid DNA delivery. J. Contro. Release 2000; 66: 229-41.
-
(2000)
J. Contro. Release
, vol.66
, pp. 229-241
-
-
Tinsley-Bown, A.M.1
Fretwell, R.2
Dowsett, A.B.3
Davis, S.L.4
Farrar, G.H.5
-
115
-
-
0034955443
-
The preparation, characterization, and evaluation of cationic microparticles for DNA vaccine delivery
-
Briones M, Singh M, Ugozzoli M et al. The preparation, characterization, and evaluation of cationic microparticles for DNA vaccine delivery. Pharm. Res. 2001; 18: 709-11.
-
(2001)
Pharm. Res.
, vol.18
, pp. 709-711
-
-
Briones, M.1
Singh, M.2
Ugozzoli, M.3
-
116
-
-
0034849493
-
Induction of potent immune responses by cationic microparticles with adsorbed HIV DNA vaccines
-
O'Hagan D, Singh M, Ugozzoli M et al. Induction of potent immune responses by cationic microparticles with adsorbed HIV DNA vaccines. J. Virol. 2001; 75: 9037-43.
-
(2001)
J. Virol.
, vol.75
, pp. 9037-9043
-
-
O'Hagan, D.1
Singh, M.2
Ugozzoli, M.3
-
117
-
-
0037133123
-
A cationic sub-micron emulsion (MF59/DOTAP) is an effective delivery system for DNA vaccines
-
Ott G, Singh M, Kazzaz J et al. A cationic sub-micron emulsion (MF59/DOTAP) is an effective delivery system for DNA vaccines. J. Control. Release 2002; 79: 1-5.
-
(2002)
J. Control. Release
, vol.79
, pp. 1-5
-
-
Ott, G.1
Singh, M.2
Kazzaz, J.3
-
119
-
-
0030879822
-
Targeted delivery of antigen to hamster nasal lymphoid tissue with M-cell-directed lectins
-
Giannasca PJ, Boden JA, Monath TP. Targeted delivery of antigen to hamster nasal lymphoid tissue with M-cell-directed lectins. Infect. Immun. 1997; 65: 4288-98.
-
(1997)
Infect. Immun.
, vol.65
, pp. 4288-4298
-
-
Giannasca, P.J.1
Boden, J.A.2
Monath, T.P.3
-
120
-
-
0030576516
-
Epithelial M cells: Gateways for mucosal infection and immunization
-
Neutra MR, Frey A, Kraehenbuhl JP. Epithelial M cells: gateways for mucosal infection and immunization. Cell 1996; 86: 345-8.
-
(1996)
Cell
, vol.86
, pp. 345-348
-
-
Neutra, M.R.1
Frey, A.2
Kraehenbuhl, J.P.3
-
122
-
-
0034283956
-
Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice
-
Dupuis M, Denis-Mize K, Woo C et al. Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice. J. Immunol. 2000; 165: 2850-58.
-
(2000)
J. Immunol.
, vol.165
, pp. 2850-2858
-
-
Dupuis, M.1
Denis-Mize, K.2
Woo, C.3
-
123
-
-
0034425778
-
Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered fas-mediated apoptosis
-
Chattergoon MA, Kim JJ, Yang JS et al. Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered fas-mediated apoptosis. Nat. Biotechnol. 2000; 18: 974-9.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 974-979
-
-
Chattergoon, M.A.1
Kim, J.J.2
Yang, J.S.3
-
124
-
-
0030218606
-
Intranasal stimulation of long-lasting immunity against aerosol ricin challenge with ricin toxoid vaccine encapsulated in polymeric microspheres
-
Yan C, Rill WL, Malli R et al. Intranasal stimulation of long-lasting immunity against aerosol ricin challenge with ricin toxoid vaccine encapsulated in polymeric microspheres. Vaccine 1996; 14: 1031-8.
-
(1996)
Vaccine
, vol.14
, pp. 1031-1038
-
-
Yan, C.1
Rill, W.L.2
Malli, R.3
-
126
-
-
0028307848
-
Microsphere absorption by the nasal mucosa of the rat
-
Alpar HO, Almeida AJ, Brown MR. Microsphere absorption by the nasal mucosa of the rat. J. Drug Target 1994; 2: 147-9.
-
(1994)
J. Drug Target
, vol.2
, pp. 147-149
-
-
Alpar, H.O.1
Almeida, A.J.2
Brown, M.R.3
-
127
-
-
0027328794
-
Protection against vaginal SIV transmission with microencapsulated vaccine
-
Marx PA, Compans RW, Gettie A et al. Protection against vaginal SIV transmission with microencapsulated vaccine. Science 1993; 260: 1323-7.
-
(1993)
Science
, vol.260
, pp. 1323-1327
-
-
Marx, P.A.1
Compans, R.W.2
Gettie, A.3
-
128
-
-
0034770990
-
Cationic microparticles are an effective delivery system for immune stimulatory CpG DNA
-
Singh M, Ott G, Kazzaz J et al. Cationic microparticles are an effective delivery system for immune stimulatory CpG DNA. Pharm. Res. 2001; 18: 1476-9.
-
(2001)
Pharm. Res.
, vol.18
, pp. 1476-1479
-
-
Singh, M.1
Ott, G.2
Kazzaz, J.3
-
129
-
-
0001058063
-
Macrophage activation through phagocytosis of muramyl dipeptide encapsulated in gelatin microspheres
-
Tabata Y, Ikada Y. Macrophage activation through phagocytosis of muramyl dipeptide encapsulated in gelatin microspheres. J. Pharm. Pharmacol. 1987; 39: 698-704.
-
(1987)
J. Pharm. Pharmacol.
, vol.39
, pp. 698-704
-
-
Tabata, Y.1
Ikada, Y.2
-
130
-
-
0034601836
-
Adjuvancy enhancement of muramyl dipeptide by modulating its release from a physicochemically modified matrix of ovalbumin microspheres. II. In vivo investigation
-
Puri N, Sinko PJ. Adjuvancy enhancement of muramyl dipeptide by modulating its release from a physicochemically modified matrix of ovalbumin microspheres. II. In vivo investigation. J. Control. Release 2000; 69: 69-80.
-
(2000)
J. Control. Release
, vol.69
, pp. 69-80
-
-
Puri, N.1
Sinko, P.J.2
-
131
-
-
12644300612
-
Development of a single-shot subunit vaccine for HIV-1. 3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120
-
Cleland JL, Barron L, Daugherty A et al. Development of a single-shot subunit vaccine for HIV-1. 3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120. J. Pharm. Sci. 1997; 85: 1350-57.
-
(1997)
J. Pharm. Sci.
, vol.85
, pp. 1350-1357
-
-
Cleland, J.L.1
Barron, L.2
Daugherty, A.3
-
132
-
-
0030952306
-
Immunogenicity and protection in small-animal models with controlled-release tetanus toxoid microparticles as a single-dose vaccine
-
Singh M, Li XM, Wang H et al. Immunogenicity and protection in small-animal models with controlled-release tetanus toxoid microparticles as a single-dose vaccine. Infect. Immun. 1997; 65: 1716-21.
-
(1997)
Infect. Immun.
, vol.65
, pp. 1716-1721
-
-
Singh, M.1
Li, X.M.2
Wang, H.3
-
133
-
-
0032210993
-
A comparison of biodegradable microparticles and MF59 as systemic adjuvants for recombinant gD from HSV-2
-
Singh M, Carlson JR, Briones M et al. A comparison of biodegradable microparticles and MF59 as systemic adjuvants for recombinant gD from HSV-2. Vaccine 1998; 16: 1822-7.
-
(1998)
Vaccine
, vol.16
, pp. 1822-1827
-
-
Singh, M.1
Carlson, J.R.2
Briones, M.3
-
134
-
-
0025845823
-
HIV and mucosal immunity
-
O'Hagan DT. HIV and mucosal immunity. Lancet 1991; 337: 1289.
-
(1991)
Lancet
, vol.337
, pp. 1289
-
-
O'Hagan, D.T.1
-
135
-
-
0036999993
-
Novel adjuvants and delivery systems for HIV vaccines
-
O'Hagan DT, Lavelle E. Novel adjuvants and delivery systems for HIV vaccines. AIDS 2002; 16 (Suppl. 4): S115-24.
-
(2002)
AIDS
, vol.16
, Issue.SUPPL. 4
-
-
O'Hagan, D.T.1
Lavelle, E.2
-
138
-
-
0033744135
-
Replicon-based vectors of positive strand RNA viruses
-
Khromykh AA. Replicon-based vectors of positive strand RNA viruses. Curr. Opin. Mol. Ther. 2000; 2: 555-69.
-
(2000)
Curr. Opin. Mol. Ther.
, vol.2
, pp. 555-569
-
-
Khromykh, A.A.1
-
139
-
-
0034575525
-
Alphavirus DNA and particle replicons for vaccines and gene therapy
-
Polo JM, Gardner JP, Ji Y et al. Alphavirus DNA and particle replicons for vaccines and gene therapy. Dev. Biol. 2000; 104: 181-5.
-
(2000)
Dev. Biol.
, vol.104
, pp. 181-185
-
-
Polo, J.M.1
Gardner, J.P.2
Ji, Y.3
-
140
-
-
0035289225
-
Alphavirus vectors: Development and potential therapeutic applications
-
Schlesinger S. Alphavirus vectors: development and potential therapeutic applications. Expert Opin. Biol. Ther. 2001; 1: 177-91.
-
(2001)
Expert Opin. Biol. Ther.
, vol.1
, pp. 177-191
-
-
Schlesinger, S.1
-
141
-
-
0037236237
-
Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways. Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines
-
Leitner WW, Hwang LN, de Veer MJ et al. Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways. Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines. Nat. Med. 2003; 9: 33-9.
-
(2003)
Nat. Med.
, vol.9
, pp. 33-39
-
-
Leitner, W.W.1
Hwang, L.N.2
De Veer, M.J.3
-
142
-
-
1842456795
-
Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines
-
Leitner WW, Hwang LN, Bergmann-Leitner ES, Finkelstein SE, Frank S, Restifo NP. Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines. Vaccine 2004; 22: 1537-44.
-
(2004)
Vaccine
, vol.22
, pp. 1537-1544
-
-
Leitner, W.W.1
Hwang, L.N.2
Bergmann-Leitner, E.S.3
Finkelstein, S.E.4
Frank, S.5
Restifo, N.P.6
-
143
-
-
0028173338
-
Self-replicating Semliki Forest virus RNA as recombinant vaccine
-
Zhou X, Berglund P, Rhodes G, Parker SE, Jondal M, Liljestrom P. Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 1994; 12: 1510-14.
-
(1994)
Vaccine
, vol.12
, pp. 1510-1514
-
-
Zhou, X.1
Berglund, P.2
Rhodes, G.3
Parker, S.E.4
Jondal, M.5
Liljestrom, P.6
-
144
-
-
0034467969
-
Infection of human dendritic cells by a sindbis virus replicon vector is determined by a single amino acid substitution in the E2 glycoprotein
-
Gardner JP, Frolov I, Perri S et al. Infection of human dendritic cells by a sindbis virus replicon vector is determined by a single amino acid substitution in the E2 glycoprotein. J. Virol. 2000; 74: 11 849-57.
-
(2000)
J. Virol.
, vol.74
, pp. 11849-11857
-
-
Gardner, J.P.1
Frolov, I.2
Perri, S.3
-
145
-
-
0035893059
-
Human immunodeficiency virus type 1 Gag-specific vaginal immunity and protection after local immunizations with sindbis virus-based replicon particles
-
Vajdy M, Gardner J, Neidleman J et al. Human immunodeficiency virus type 1 Gag-specific vaginal immunity and protection after local immunizations with sindbis virus-based replicon particles. J. Infect. Dis. 2001; 184: 1613-16.
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 1613-1616
-
-
Vajdy, M.1
Gardner, J.2
Neidleman, J.3
-
146
-
-
0037154783
-
Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses
-
Balasuriya UB, Heidner HW, Davis NL et al. Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses. Vaccine 2002; 20: 1609-17.
-
(2002)
Vaccine
, vol.20
, pp. 1609-1617
-
-
Balasuriya, U.B.1
Heidner, H.W.2
Davis, N.L.3
-
147
-
-
0037105524
-
Vaccination with recombinant alphavirus or immunestimulating complex antigen against respiratory syncytial virus
-
Chen M, Hu KF, Rozell B, Orvell C, Morein B, Liljestrom P. Vaccination with recombinant alphavirus or immunestimulating complex antigen against respiratory syncytial virus. J. Immunol. 2002; 169: 3208-16.
-
(2002)
J. Immunol.
, vol.169
, pp. 3208-3216
-
-
Chen, M.1
Hu, K.F.2
Rozell, B.3
Orvell, C.4
Morein, B.5
Liljestrom, P.6
-
148
-
-
0035991717
-
Alphavirus replicon particles as candidate HIV vaccines
-
Davis NL, West A, Reap E et al. Alphavirus replicon particles as candidate HIV vaccines. IUBMB Life 2002; 53: 209-11.
-
(2002)
IUBMB Life
, vol.53
, pp. 209-211
-
-
Davis, N.L.1
West, A.2
Reap, E.3
-
149
-
-
0141521625
-
An alphavirus replicon particle chimera derived from Venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector
-
Perri S, Greer CE, Thudium K et al. An alphavirus replicon particle chimera derived from Venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector. J. Virol. 2003; 77: 10 394-403.
-
(2003)
J. Virol.
, vol.77
, pp. 10394-10403
-
-
Perri, S.1
Greer, C.E.2
Thudium, K.3
-
150
-
-
0041817682
-
Enhanced mucosal and systemic immune responses to Helicobacter pylori antigens through mucosal priming followed by systemic boosting immunizations
-
Vajdy M, Singh M, Ugozzoli M et al. Enhanced mucosal and systemic immune responses to Helicobacter pylori antigens through mucosal priming followed by systemic boosting immunizations. Immunology 2003; 110: 86-94.
-
(2003)
Immunology
, vol.110
, pp. 86-94
-
-
Vajdy, M.1
Singh, M.2
Ugozzoli, M.3
-
151
-
-
9344271504
-
Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intra-nasal and parenteral immunizations
-
in press
-
Vajdy M, Singh M, Kazzaz J et al. Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intra-nasal and parenteral immunizations. AIDS Res. Hum. Retroviruses 2004; 20: in press.
-
(2004)
AIDS Res. Hum. Retroviruses
, vol.20
-
-
Vajdy, M.1
Singh, M.2
Kazzaz, J.3
|