Apoptosis is essential for the increased efficacy of alphaviral replicase-based DNA vaccines

Vaccine

Volumn 22, Issue 11-12, 2004, Pages 1537-1544

  Leitner, Wolfgang W ^a   Hwang, Leroy N ^a   Bergmann Leitner, Elke S ^b   Finkelstein, Steven E ^a   Frank, Stephan ^c   Restifo, Nicholas P ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

Alphavirus; Apoptosis; Bcl XL; DNA vaccines

Indexed keywords

DIFFERENTIATION ANTIGEN; DNA VACCINE; PROTEIN BCL XL; PROTEIN TRP 1; UNCLASSIFIED DRUG;

ALPHA VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; IMMUNOGENICITY; IMMUNOPHARMACOLOGY; IMMUNOREACTIVITY; IN VIVO STUDY; MELANOCYTE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REPLICON; TUMOR CELL; VIRAL GENE THERAPY;

ANIMALS; ANTIBODIES, VIRAL; APOPTOSIS; BCL-X PROTEIN; CANCER VACCINES; CELL LINE; CELL SURVIVAL; CRICETINAE; DNA; FLOW CYTOMETRY; MELANOMA; MICE; MICE, INBRED C57BL; PLASMIDS; PROTO-ONCOGENE PROTEINS C-BCL-2; REPLICON; SINDBIS VIRUS; TRANSFECTION; VACCINES, DNA; VIRAL VACCINES;

EID: 1842456795     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2003.10.013     Document Type: Article

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