DNA immunization against herpes simplex virus: Enhanced efficacy using a sindbis virus-based vector

Journal of Virology

Volumn 72, Issue 2, 1998, Pages 950-958

  Hariharan, Mangala J ^a   Driver, David A ^a   Townsend, Kay ^a   Brumm, Duane ^a   Polo, John M ^a   Belli, Barbara A ^a   Catton, Donald J ^a   Hsu, David ^a   Mittelstaedt, Denise ^a   Mccormack, James E ^a   Karavodin, Linda ^a   Dubensky Jr , Thomas W ^a   Chang, Stephen M W ^a   Banks, Theresa A ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; HERPES SIMPLEX VIRUS; IMMUNIZATION; INFECTION PREVENTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA REPLICATION; SINDBIS VIRUS;

EID: 0031882102     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.2.950-958.1998     Document Type: Article

References (54)

1. Banks, T. A., E. A. Allen, S. Dasgupta, R. Sandri-Goldin, and B. T. Rouse. 1991. Herpes simplex virus type 1-specific cytotoxic T lymphocytes recognize immediate-early protein ICP27. J. Virol. 65:3185-3191.
2. Banks, T. A., F. J. Jenkins, S. Kanangat, S. Nair, S. Dasgupta, C. M. Foster, and B. T. Rouse. 1994. Vaccination with the immediate-early protein ICP47 of herpes simplex virus type 1 (HSV-1) induces virus-specific lymphoproliferation, but fails to protect against lethal challenge. Virology 200:236-245.
3. Bourne, N., G. N. Milligan, M. R. Schleiss, D. I. Bernstein, and L. R. Stanberry. 1996. DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2. Vaccine 14:1230-1234.
4. Bourne, N., L. R. Stanberry, D. I. Bernstein, and D. Lew. 1996. DNA immunization against experimental genital herpes simplex virus infection. J. Infect. Dis. 173:800-807.
5. Boyer, J. D., K. E. Ugen, B. Wang, M. Agadjanyan, L. Gilbert, M. L. Bagarazzi, M. Chattergoon, P. Frost, A. Javadian, W. V. Williams, Y. Refaeli, R. B. Ciccarelli, D. McCallus, L. Coney, and D. B. Weiner. 1997. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nat. Med. 3:526-532.
6. Caley, I. J., M. R. Betts, D. M. Irlbeck, N. L. Davis, R. Swanstrom, J. A. Frelinger, and R. E. Johnston. 1997. Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector. J. Virol. 71:3031-3038.
7. Chapsal, J. M., and L. Pereira. 1988. Characterization of epitopes on native and denatured forms of herpes simplex virus glycoprotein B. Virology 164: 427-434.
8. Conry, R. M., G. Widera, A. F. LoBuglio, J. T. Fuller, S. E. Moore, D. L. Barlow, J. Turner, N.-S. Yang, and D. T. Curiel. 1996. Selected strategies to augment polynucleolide immunization. Gene Ther. 3:67-74.
9. Donnelly, J. J., J. B. Ulmer, J. W. Shiver, and M. A. Liu. 1997. DNA vaccines. Annu. Rev. Immunol. 15:617-648.
10. Driver, D. A., E. M. Latham, J. M. Polo, B. A. Belli, T. A. Banks, S. Chada, D. Brumm, S. M. W. Chang, S. J. Mento, D. J. Jolly, and T. W. Dubensky, Jr. 1995. Layered amplification of gene expression with a DNA gene delivery system. Ann. N. Y. Acad. Sci. 772:261-264.
11. Dubensky, T. W., Jr., D. A. Driver, J. M. Polo, B. A. Belli, E. M. Latham, C. E. Ibanez, S. Chada, D. Brumm, T. A. Banks, S. J. Mento, D. J. Jolly, and S. M. W. Chang. 1996. Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer. J. Virol. 70:508-519.
12. Ertl, H. C. J., and Z. Q. Xiang. 1996. Genetic immunization. Viral Immunol. 9:1-9.
13. Frolov, I., T. A. Hoffman, B. M. Pragai, S. A. Dryga, H. V. Huang, S. Schlesinger, and C. M. Rice. 1996. Alphavirus-based expression vectors: strategies and applications. Proc. Natl. Acad. Sci. USA 93:11371-11377.
14. Fynan, E. F., R. G. Webster, D. H. Fuller, J. R. Haynes, J. C. Santoro, and H. R. Robinson. 1993. DNA vaccines: protective, immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. USA 90: 11478-11482.
15. Geissler, M. A., K. Gesien, K. Tokushige, and J. R. Wands. 1997. Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids. J. Immunol. 158:1231-1237.
16. Ghiasi, H., S. Cai, S. Slanina, A. B. Nesburn, and S. L. Wechsler. 1995. Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge. Antiviral Res. 28:147-157.
17. Gregoriàdis, G., R. Saffie, and J. B. de Souza. 1997. Liposome-mediated DNA vaccination. FEBS Lett. 402:107-110.
18. Hanke, T., F. L. Graham, K. L. Rosenthal, and D. C. Johnson. 1991. Identification of an immunodominant cytotoxic T-lymphocyte recognition site in glycoprotein B of herpes simplex virus by using recombinant adenovirus vectors and synthetic peptides. J. Virol. 65:1177-1186.
19. Haynes, J. R., D. H. Fuller, M. D. Eisenbraun, M. J. Ford, and T. M. Pertmer. 1994. Accell particle-mediated DNA immunization elicits humoral, cytotoxic and protective responses. AIDS Res. Hum. Retroviruses 10(Suppl. 2):S43-S45.
20. Hartikka, J., M. Sawdey, F. Cornefert-Jensen, M. Margalith, K. Barnhart, M. Nolasco, H. L. Vahlsing, J. Meek, M. Marquet, P. Hobart, J. Norman, and M. Manthorpe. 1996. An improved plasmid DNA expression vector for direct injection into skeletal muscle. Hum. Gene Ther. 7:1205-1217.
21. Herweijer, H., J. S. Latendresse, P. Williams, G. Zhang, I. Danko, S. Schlesinger, and J. A. Wolff. 1995. A plasmid-based self-amplifying Sindbis virus vector. Hum. Gene Ther. 6:1161-1167.
22. Huang, H. V. 1996. Sindbis virus vectors for expression in animal cells. Curr. Opin. Biotechnol. 7:531-535.
23. Huang, Z.-M., and T. S. B. Yen. 1995. Role of the hepatitis B virus post-transcriptional regulatory clement in export of intronless transcripts. Mol. Cell. Biol. 15:3864-3869.
24. Kim, J. J., V. Ayyavoo, M. L. Bagarazzi, M. A. Chattergoon, K. Dang, B. Wang, J. D. Boyer, and D. B. Weiner. 1997. In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen. J. Immunol. 158:816-826.
25. Klinman, D. M., G. Yamshchikov, and I. Ishigatsubo. 1997. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 158:3635-3639.
26. Kriesel, J. D., S. L. Spruance, R. A. Daynes, and B. A. Araneo. 1996. Nucleic acid vaccine encoding gD2 protects mice from herpes simplex virus type 2 disease. J. Infect. Dis. 173:536-541.
27. Kuklin, N., M. Daheshia, K. Karem, E. Manickan, and B. T. Rouse. 1997. Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization. J. Virol. 71:3138-3145.
28. Liljestrom, P. 1994. Alphavirus expression systems. Curr. Opin. Biotechnol. 5:495-500.
29. Lu, S., J. Arthos, D. C. Montefiori, Y. Yasutomi, K. Manson, F. Mustafa, E. Johnson, J. C. Santoro, J. Wissink, J. I. Mullins, J. R. Haynes, N. L. Letvin, M. Wyand, and H. L. Robinson. 1996. Simian immunodeficiency virus DNA vaccine trial in macaques. J. Virol. 70:3978-3991.
30. Manickan, E., R. J. D. Rouse, Z. Yu, W. S. Wire, and B. T. Rouse. 1995. Genetic immunization against herpes simplex virus: protection is mediated by CD4+ T lymphocytes. J. Immunol. 155:259-265.
31. Manickan, E., Z. Yu, R. J. D. Rouse, W. S. Wire, and B. T. Rouse. 1995. Induction of protective immunity against herpes simplex virus with DNA encoding the immediate-early protein ICP27. Viral Immunol. 8:53-61.
32. Manickan, E., S. Kanangat, R. J. D. Rouse, Z. Yu, and B. T. Rouse. 1997. Enhancement of immune response to naked DNA vaccines by immunization with transfected dendritic cells. J. Leukocyte Biol. 61:125-132.
33. McClements, W. L., M. E. Armstrong, R. D. Keys, and M. A. Liu. 1996. Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease. Proc. Natl. Acad. Sci. USA 93:11414-11420.
34. Montgomery, D. L., J. W. Shiver, K. R. Leander, H. C. Perry, A. Friedman, D. Martinez, J. B. Ulmer, J. J. Donnelly, and M. A. Liu. 1993. Heterologous and homologous protection against influenza A by DNA vaccination-optimization of DNA vectors. DNA Cell Biol. 12:777-783.
35. Mumper, R. J., J. G. Duguid, K. Anwer, M. K. Barron, H. Nitta, and A. P. Rolland. 1996. Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle. Pharm. Res. 13:701-709.
36. Nguyen, L., D. M. Knipe, and R. W. Finberg. 1994. Mechanism of virus-induced Ig subclass shifts. J. Immunol. 152:478-482.
37. Pardoll, D. M., and A. M. Beckerleg. 1995. Exposing the immunology of naked DNA vaccines. Immunity 3:165-169.
38. Rouse, R. J. D., S. K. Nair, S. L. Lydy, J. C. Bowen, and B. T. Rouse. 1994. Induction in vivo of primary cytotoxic T-lymphocyte responses with DNA encoding herpes simplex virus proteins. J. Virol. 68:5685-5689.
39. Sato, Y., M. Roman, H. Tighe, D. Lee, M. Corr, M.-D. Nguyen, G. J. Silverman, M. Lotz, D. A. Carson, and E. Raz. 1996. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 273:352-354.
40. Simmons, A., and A. A. Nash. 1984. Zosteriform spread of herpes simplex virus as a model of recrudescence. J. Virol. 52:816-821.
41. Stephan, D. J., Z.-Y. Yang, R. D. Simari, H. San, C. J. Wheller, P. L. Felgner, D. Gordon, G. J. Nabel, and E. G. Nabel. 1996. A novel cationic liposome DNA complex enhances the efficacy of arterial gene transfer in vivo. Hum. Gene Ther. 7:1803-1812.
42. Strauss, J. H., and E. G. Strauss. 1994. The alphaviruses: gene expression, replication, and evolution. Microbiol. Rev. 58:491-562.
43. Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. 1. Data analysis. J. Immunol. 126:1614-1619.
44. Tsuji, T., K. Hamajima, J. Fukushima, K.-Q. Xin, N. Ishi, I. Aoki, Y. Ishigatsubo, K. Tani, S. Kawamotoo, Y. Nitta, J. Miyazaki, W. C. Koff, T. Okubo, and K. Okuda. 1997. Enhancement of cell-mediated immunity against HIV-1 induced by coinoculation of plasmid encoded HIV-1 antigen with plasmid expressing IL-12. J. Immunol. 158:4008-4013.
45. Ulmer, J. B., J. J. Donnelly, and M. A. Liu. 1996. Toward the development of DNA vaccines. Curr. Opin. Biotechnol. 7:653-658.
46. Vilcek, J., and G. C. Sen. 1996. Interferons and other cytokines, p. 375-399. In B. N. Fields. D. M. Knipe, and P. M. Howley (ed.), Fields virology. Lippincott-Raven. Philadelphia, Pa.
47. Vitadello, M., M. V. Schiaffino, A. Picard, M. Scarpa, and S. Shiaffino. 1994. Gene transfer in regenerating muscle. Hum. Gene Ther. 5:11-18.
48. Warner, J. F., C.-G. Anderson, L. Laube, D. J. Jolly, K. Townsend, S. Chada, and D. St. Louis. 1991. Induction of HIV-specific CTL and antibody responses in mice using retroviral vector-transduced cells. AIDS Res. Hum. Retroviruses 7:645-655.
49. Wells, D. J. 1993. Improved gene transfer by direct plasmid injection associated with regeneration in mouse skeletal muscle. FEBS Lett. 332:179-182.
50. Wheeler, C. J., P. L. Feigner, Y. J. Tsai, J. Marshall, L. Sukhu, G. Doh, J. Hartikka, J. Nietupski, M. Manthorpe, M. Nichols, M. Plewe, X. Liang, J. Norman, A. Smith, and S. H. Cheng. 1996. A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc. Natl. Acad. Sci. USA 93:11454-11459.
51. Xiang, Z. Q., and H. C. J. Ertl. 1995. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmid expressing cytokines. Immunity 2:129-135.
52. Xiong, C., R. Lewis, P. Shen, S. Schlesinger, C. M. Rice, and H. V. Huang. 1989. Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science 243:1188-1191.
53. Zhou, X., P. Berglund, G. Rhodes, S. E. Parker, M. Jondal, and P. Liljestrom. 1994. Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 12:1510-1514.
54. Zhou, X., P. Berglund, H. Zhao, P. Liljestrom, and M. Jondal. 1995. Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus. Proc. Natl. Acad. Sci. USA 92:3009-3013.