A perspective on the current strategies for the treatment of obesity

Current Drug Targets: CNS and Neurological Disorders

Volumn 3, Issue 5, 2004, Pages 341-356

  Joyal, Steven V ^a,b  

^a BRISTOL MYERS SQUIBB   (United States)

^b NONE   (United States)

Author keywords

Bariatric surgery; CLA; Diet; Ephedrine; Hydroxycitrate; Obesity; Orlistat; Pyruvate; Sibutramine; Weight loss

Indexed keywords

ALKALOID; ANTIMIGRAINE AGENT; ANTIOBESITY AGENT; CAFFEINE; CHINESE DRUG; CHROMIUM DERIVATIVE; CHROMIUM PICOLINATE; CONJUGATED LINOLEIC ACID; CYCLOSPORIN; DEXFENFLURAMINE; EPHEDRA EXTRACT; EPHEDRA SINICA EXTRACT; EPHEDRINE; FENFLURAMINE; GARCINIA CAMBOGIA EXTRACT; HERBACEOUS AGENT; HYDROXYCITRIC ACID; MONOAMINE OXIDASE INHIBITOR; NON PRESCRIPTION DRUG; OPIATE DERIVATIVE; PHENTERMINE; PLANT EXTRACT; PYRUVIC ACID DERIVATIVE; SEROTONIN UPTAKE INHIBITOR; SIBUTRAMINE; SUNFLOWER OIL; TETRAHYDROLIPSTATIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VITAMIN D;

ANXIETY DISORDER; AUTONOMIC NEUROPATHY; BARIATRIC SURGERY; BEHAVIOR MODIFICATION; BILIARY TRACT DISEASE; CANCER RISK; CARBOHYDRATE DIET; CARDIOVASCULAR DISEASE; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; DIET SUPPLEMENTATION; DIET THERAPY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FATALITY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SAFETY; DYSLIPIDEMIA; ENVIRONMENTAL FACTOR; FOOD COMPOSITION; GASTROINTESTINAL SYMPTOM; HEALTH CARE COST; HEALTH CARE SYSTEM; HEART ARRHYTHMIA; HEART INFARCTION; HEART PALPITATION; HEREDITY; HUMAN; HYPERACTIVITY; HYPERGLYCEMIA; HYPERTENSION; KINESIOTHERAPY; LIFESTYLE; LOW CALORY DIET; MACRONUTRIENT; MENTAL DISEASE; META ANALYSIS; MOOD DISORDER; MUTAGENICITY; NAUSEA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PATHOPHYSIOLOGY; PHYSICAL ACTIVITY; PREVALENCE; PULMONARY HYPERTENSION; REVIEW; RISK FACTOR; SEIZURE; SLEEP APNEA SYNDROME; STEATORRHEA; STROKE; SYSTEMATIC REVIEW; TACHYCARDIA; UNITED STATES; VALVULAR HEART DISEASE; VOMITING; WEIGHT REDUCTION;

ANTI-OBESITY AGENTS; BARIATRICS; CHROMIUM; CITRATES; CYCLOBUTANES; ENERGY INTAKE; EPHEDRINE; EXERCISE THERAPY; GARCINIA CAMBOGIA; HUMANS; LACTONES; LINOLEIC ACIDS, CONJUGATED; MEDICINE, HERBAL; OBESITY; PHYTOTHERAPY; PYRUVIC ACID;

EID: 9144244969     PISSN: 1568007X     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568007043336978     Document Type: Review

References (178)

1. Centers for Disease Control and Prevention (CDC). Trends in intake of energy and macronutrients - United States, 1971-2000. MMWR Morb. Mortal Wkly. Rep., 2004 3(4), 80-2.
2. Centers for Disease Control and Prevention (CDC). Prevalence of no leisure-time physical activity - 35 States and the District of Columbia, 1988-2002. MMWR Morb. Mortal Wkly. Rep., 2004 53(4), 82-6.
3. Centers for Disease Control and Prevention (CDC). Prevalence of physical activity, including lifestyle activities among adults - United States, 2000-2001. MMWR Morb. Mortal Wkly. Rep., 2003, 52(32), 764-9.
4. Ogden, C.L., Carroll, M.D., Flegal, K.M. Endocrinol. Metab. Clin. North Am., 2003, 32(4), 741-60.
5. El-Atat, F., Aneja, A., Mcfarlane, S., Sowers, J. Endocrinol. Metab. Clin. North Am., 2003, 32(4), 823-54.
6. Manson, J.E., Skerrett, P.J., Greenland, P., VanItallie, T.B. Arch. Intern. Med., 2004, 164(3), 249-58.
7. Fang, J. Am. J. Gastroenterol., 2003, 98(9) 2097-8.
8. Bungum, T., Satterwhite, M., Jackson, A.W., Morrow, J.R. Jr. Am. J. Health Behav., 2003, 27(4), 456-62.
9. Grantmakers in Health, Washington, D.C., USA. Weighing in on obesity, America's growing health epidemic. Issue brief (Grantmakers Health). 2001, 11, 1-32.
10. Katz, D.L. Public Health Rev., 2003, 31(1), 33-44.
11. Collin, A., Malheiros, R.D., Moraes, V.M., Van As, P., Darras, V.M., Taouis, M., Decuypere, E., Buyse, J. Br. J. Nutr., 2003, 90(2), 261-9.
12. Felicetti, L.A., Robbins, C.T., Shipley, L.A. Physiol. Biochem. Zool., 2003, 76(2), 256-61.
13. Piers, L.S., Walker, K.Z., Stoney, R.M., Soares, M.J., O'Dea, K. Int. J. Obes. Relat. Metab. Disord., 2002, 26(6), 814-21.
14. Blaak, E.E., Saris, W.H. Metabolism, 1996, 45(10), 1235-42.
15. Suen, V.M., Silva, G.A., Tannus, A.F., Unamuno, M.R., Marchini, J.S. Nutrition, 2003, 19(9), 703-7.
16. Adriaens, M.P., Schoffelen, P.F., Westerterp, K.R. Br. J. Nutr., 2003, 90(2), 419-23.
17. Zanni, E.E., Zannis, V.I., Blum, C.B., Herbert, P.N., Breslow, J.L. J. Lipid Res., 1987, 28(5), 518-27.
18. Asztalos, B., Lefevre, M., Wong, L., Foster, T.A., Tulley, R., Windhauser, M., Zhang, W., Roheim, P.S. J. Lipid Res., 2000 41(3), 321-8.
19. Reaven, G.M. Curr. Atheroscler. Rep., 2000, 2(6), 503-7.
20. Reaven, G.M. Curr. Opin. Lipidol., 1997, 8(1) 23-7.
21. Abbasi, F., McLaughlin, T., Lamendola, C., Kim, H.S., Tanaka, A., Wang, T., Nakajima, K., Reaven, G.M. Am. J. Cardiol., 2000 1, 85(1), 45-8.
22. He, K., Merchant, A., Rimm, E.B., Rosner, B.A., Stampfer, M.J., Willett, W.C., Ascherio, A. BMJ, 2003, 327(7418 , 777-82.
23. Hu, F.B., Stampfer, M.J., Manson, J.E., Ascherio, A., Colditz, G.A., Speizer, F.E., Hennekens, C.H., Willett, W.C. Am. J. Clin. Nutr., 1999, 70(6), 1001-8.
24. Hadorn, D.C., Baker, D., Hodges, J.S., Hicks, N. J. Clin. Epidemiol., 1996, 49(7), 749-54.
25. Dansinger, M.L., Gleason, J. L., Griffith, J.L., et al., " One Year Effectiveness of the Atkins, Ornish, Weight Watchers, and Zone Diets in Decreasing Body Weight and Heart Disease Risk,"Presented at the American Heart Association Scientific Sessions November 12,2003 in Orlando, Florida.
26. Foster, G.D., Wyatt, H.R., Hill, J.O., McGuckin, B.G., Brill, C., Mohammed, B.S., Szapary, P.O., Rader, D.J., Edman, J.S., Klein, S. N. Engl. J. Med., 2003, 22, 348(21), 2082-90.
27. Hays, J.H., DiSabatino, A., Gorman, R.T., Vincent, S., Stillabower, M.E. Mayo Clin. Proc., 2003, 78(11), 1331-6.
28. O'Brien, K.D., Brehm, B.J., Seeley, R.J., "Greater Reduction in Inflammatory Markers With a Low Carbohydrate Diet than with a Calorically Matched Low Fat Diet," Presented at American Heart Association's Scientific Sessions 2002 on Tuesday, November 19, 2002, Abstract ID, 117597.
29. Samaha, F.F., Iqbal, N., Seshadri, P., Chicano, K.L., Daily, D.A., McGrory, J., Williams, T., Williams, M., Gracely, E.J., Stern, L. N. Engl. J. Med., 2003, 348(21), 2074-81.
30. Astrup, A., Grunwald, G.K., Melanson, E.L., Saris, W.H., Hill, J.O. Int. J. Obes. Relat. Metab. Disord., 2000, 24(12), 1545-52.
31. Willett, W.C. Obes. Rev., 2002, 3(2), 59-68.
32. Astrup, A. Obes. Rev., 2002, 3(2), 57-8.
33. Raynor, H.A., Epstein, L.H. Appetite, 2003, 40(1), 15-24.
34. Epstein, L.H., Truesdale, R., Wojcik, A., Paluch, R.A., Raynor, H.A. Physiol. Behav., 2003, 78(2), 221-7.
35. Hetherington, M.M., Stoner, S.A., Andersen, A.E., Rolls, B.J. Int. J. Eat. Disord., 2000, 28(3), 272-83.
36. O'Keefe, J.H. Jr, Cordain, L. Mayo Clin. Proc., 2004 79(1), 101-8.
37. Cordain, L., Watkins, B.A., Florant, G.L., Kelher, M., Rogers, L., Li, Y. Eur. J. Clin. Nutr., 2002, 56(3), 181-91.
38. Eaton, S.B., Cordain, L., Eaton, S.B. World Rev. Nutr. Diet. 2001, 90, 5-12.
39. Bell, E.A., Rolls, B.J. Am. J. Clin. Nutr., 2001, 73(6), 1010-8.
40. Rolls, B.J., Bell, E.A., Waugh, B.A. Am. J. Clin. Nutr. 2000, 72(2), 361-8.
41. Bell, E.A., Roe, L.S, Rolls, B. J. Physiol. Behav., 2003, 78(4-5), 593-600.
42. Prevalence of health-care providers asking older adults about their physical activity levels - United States, 1998. MMWR Morb Mortal Wkly Rep. 2002, 51(19), 412-4.
43. Livingstone, M.B., Robson, P.J., Wallace, J.M., McKinley, M.C. Proc. Nutr. Soc., 2003, 62(3), 681-701.
44. Boreham, C., Riddoch, C. J. Sports Sci., 2001, 19(12), 915-29.
45. Isasi, C.R., Deckelbaum, R.J., Tracy, R.P., Starc, T.J., Berglund, L., Shea, S. Pediatrics, 2003, 111(2), 332-8.
46. Roberts, S.S. Diabetes Forecast., 2002, 55(8) 98-100.
47. Santa-Clara, H., Fernhall, B., Baptista, F., Mendes, M., Bettencourt Sardinha, L. 2003, 52(11), 1413-7.
48. Willey, K.A., Singh, M.A. Diabetes Care, 2003, 26(5), 1580-8.
49. Holten, M.K., Zacho, M., Gaster, M., Juel, C., Wojtaszewski, J.F., Dela, F. Diabetes, 2004, 53(2), 294-305.
50. Castaneda, C., Layne, J.E., Munoz-Orians, L., Gordon, P.L., Walsmith, J., Foldvari, M., Roubenoff, R., Tucker, K.L., Nelson, M.E. Diabetes Care, 2002, 25(12), 2335-41.
51. Wang, L., van Belle, G., Kukull, W.B., Larson, E.B. J. Am. Geriatr. Soc., 2002, 50(9), 1525-34.
52. Poehlman, E.T., Turturro, A., Bodkin, N., Cefalu, W., Heymsfield, S., Holloszy, J., Kemnitz, J. J. Gerontol. A. Biol. Sci. Med. Sci., 2001, 56, 45-54.
53. Lee, I.M., Blair, S.N., Allison, D.B., Folsom, A.R., Harris, T.B., Manson, J.E., Wing, R.R. J. Gerontol. A. Biol. Sci. Med. Sci. 2001, 56, 7-19.
54. Heilbronn, L.K., Ravussin, E. Am. J. Clin. Nutr., 2003, 78(3), 361-9.
55. Chevion, S., Moran, D.S., Heled, Y., Shani, Y., Regev, G., Abbou, B., Berenshtein, E., Stadtman, E.R., Epstein, Y. Proc. Natl. Acad. Sci. U.S.A., 2003, 100(90), 5119-23.
56. Blair, S.N., Kohl, H.W., Gordon, N.F., Paffenbarger, R.S. Jr. Annu. Rev. Public Health, 1992, 13, 99-126.
57. Blair, S.N., Connelly, J.C. Res. Q. Exerc. Sport, 1996, 67(2), 193-205.
58. Vuori, I.M. Public Health Nutr., 2001, 4(2B) 517-28.
59. Haskell, W.L. J.B. Wolffe Memorial Lecture. Health consequences of physical activity, understanding and challenges regarding dose-response. Med. Sci. Sports Exerc., 1994, 26(6), 649-60.
60. American College of Sports Medicine Position Stand. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med. Sci. Sports Exerc.. 1998, 30(6 , 975-91.
61. Centers for Disease Control and Prevention (CDC). Prevalence of no leisure-time physical activity - 35 States and the District of Columbia, 1988-2002. MMWR Morb. Mortal. Wkly. Rep., 2004, 53(4), 82-6.
62. Zhang, Q., Wang, Y. Soc. Sci. Med., 2004, 58(6), 1171-80.
63. Nutrition Business Journal, Supplement Business Report 2002.
64. "Weight-Loss Advertising, An Analysis of Current Trends" A Federal Trade Commission Staff Report (Sept. 2002) ("Weight Loss Advertising Report").
65. D'Orazio, N., Ficoneri, C., Riccioni, G., Conti, P., Theoharides, T.C., Bollea, M.R. Int. J. Immunopathol. Pharmacol., 2003, 16(3), 215-20.
66. Ip, M.M., Masso-Welch, P.A., Ip, C. J. Mammary Gland Biol. Neoplasia, 2003, 8(1), 103-18.
67. Brown, J.M., McIntosh, M.K. J. Nutr., 2003, 133(10), 3041-6.
68. Ntambi, J.M., Choi, Y., Park, Y., Peters, J.M., Pariza, M.W. Can. J. Appl. Physiol., 2002, 27(6), 617-28.
69. Belury, M.A. J. Nutr., 2002, 132(10), 2995-8.
70. Nagao, K., Inoue, N., Wang, Y.M., Yanagita, T. Biochem. Biophys. Res. Commun., 2003, 310(2), 562-6
71. Nagao, K., Inoue, N., Wang, Y.M., Hirata, J., Shimada, Y., Nagao, T., Matsui, T., Yanagita, T. Biochem. Biophys. Res. Commun., 2003, 306(1), 134-8.
72. Houseknecht, K.L., Vanden Heuvel, J.P., Moya-Camarena, S.Y., Portocarrero, C.P., Peck, L.W., Nickel, K.P., Belury, M.A. Biochem. Biophys. Res. Commun., 244(3), 678-82. Erratum in, Biochem. Biophys. Res. Commun., 1998, 247(3), 911.
73. Takahashi, Y., Kushiro, M., Shinohara, K., Ide, T. Comp. Biochem. Physiol. B. Biochem. Mol. Biol., 2002, 133(3), 395-404.
74. DeLany, J.P., Blohm, F., Truett, A.A., Scimeca, J.A., West, D.B. Am. J. Physiol., 1999, 276(4 Pt. 2), R1172-9.
75. West, D.B., Delany, J.P., Camet, P.M., Blohm, F., Truett, A.A., Scimeca, J. Am. J. Physiol., 1998, 275(3 Pt. 2), R667-72.
76. Blankson, H., Stakkestad, J.A., Fagertun, H., Thom, E., Wadstein, J., Gudmundsen, O. J. Nutr., 2000, 130(12 , 2943-8.
77. Zambell, K.L., Keim, N.L., Van Loan, M.D., Gale, B., Benito, P., Kelley, D.S., Nelson, G.J. expenditure, 2000, 35(7), 777-82.
78. Smedman, A., Vessby, B. Lipids, 2001, 36(8) 773-81.
79. Kamphuis, M.M., Lejeune, M.P., Saris, W.H., Westerterp-Plantenga, M.S. Int. J. Obes. Relat. Metab. Disord., 2003, 27(7), 840-7.
80. Terpstra, A.H. J. Nutr., 2001, 131(7), 2067-8.
81. Gaullier, J.M., Berven, G, Blankson, H., Gudmundsen, O. Lipids, 2002, 37(11), 1019-25.
82. Schulman, S. Public Health Rep., 2003, 118(6) 487-92.
83. Lee, M.K., Cheng, B.W., Che, C.T., Hsieh, D.P. Toxicol. Sci., 2000, 56(2), 424-30.
84. Ling, M., Piddlesden, S.J., Morgan, B.P. Clin. Exp. Immunol., 1995, 102(3), 582-8.
85. Schaneberg, B.T., Crockett, S., Bedir, E., Khan, I.A. Phytochemistry, 2003, 911-8.
86. Haller, C.A., Benowitz, N.L. N. Engl. J. Med., 2000 343(25), 1833-8.
87. Shekelle, P., Morton, S., Maglione, M., et al. Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement, Clinical Efficacy and Side Effects. Evidence Report/Technology Assessment No. 76 (Prepared by Southern California Evidence-based Practice Center, RAND, under Contract No 290-97-0001, Task Order No. 9). AHRQ Publication No. 03-E022. Rockville, MD, Agency for Healthcare Research and Quality. February 2003.
88. Vincent, J.B. Sports Med., 2003, 33(3), 213-30.
89. Gargas, M.L., Norton, R.L., Paustenbach, D.J., Finley, B.L. Drug Metab. Dispos., 1994, 22(4), 522-9.
90. Stearns, D.M, Wise, J.P. Sr, Patierno, S.R., Wetterhahn, K.E. FASEB J., 1995, 9(15), 1643-8.
91. Bagchi, D., Bagchi, M., Balmoori, J., Ye, X., Stohs, S.J. Res. Commun. Mol. Pathol. Pharmacol., 1997, 97(3), 335-46. Erratum in, Res. Commun. Mol. Pathol. Pharmacol., 1998, 99(2), 240.
92. Stearns, D.M., Silveira, S.M., Wolf, K.K., Luke, A.M. Mutat. Res., 2002, 15, 513(1-2), 135-42.
93. Speetjens, J.K., Collins, R.A., Vincent, J.B., Woski, S.A. Chem. Res. Toxicol., 1999, 12(6), 483-7.
94. Kato, I., Vogelman, J.H., Dilman, V., Karkoszka, J., Frenkel, K., Durr, N.P., Orentreich, N., Toniolo, P. Eur. J. Epidemiol., 1998, 14(6), 621-6.
95. Hepburn, D., Burney, J., Woski, S.and Vincent, J. Polyhedron, 2003, 22(12), 455-463.
96. Pittler, M.H., Stevinson, C., Ernst, E. Int. J. Obes. Relat. Metab. Disord., 2003, 27(4), 522-9.
97. Anderson, R.A., Cheng, N., Bryden, N.A., Polansky, M.M., Chi, J., Feng, J. Diabetes, 1997, 46, 1786-91.
98. Bahadori, B., Wallner, S., Hacker, C., Boes, U., Komorowski, J.R., Wascher, T.C. Diabetes, 1999, 48(suppl.), A349 (abstr).
99. Jovanovic-Peterson, L., Gutierrez, M., Peterson, C.M. J. Trace Elem. Exp. Med., 1999, 12, 91-7.
100. Althuis, M.D., Jordan, N.E., Ludington, E.A., Wittes, J.T. Am. J. Clin. Nutr., 2002, 76(1), 148-55.
101. Watson, J.A., Lowenstein, J.M. J. Biol. Chem., 1970 245, 5993-6002.
102. Watson, J.A., Fang, M., Lowenstein, J.M. Arch. Biochem. Biophys., 1969, 35, 209-217.
103. Lowenstein, J.M. J. Biol. Chem., 1971, 246, 629-632.
104. Sullivan, A.C., Triscari, J., Hamilton, J.G., Neal Miller, O. Lipids, 1973, 9, 129-134.
105. Nageswara, R., Sakeriak, K.K. Nutr. Res., 1988, 8, 209-212.
106. Badmaev, V., Majeed, M. Open field, physician controlled, clinical evaluation of botanical weight loss formula citrin. Presented at, Nutracon 1995, Nutriceuticals, Dietary Supplements and Functional Foods; July 11-13, 1995; Las Vegas, Nev.
107. Conte, A.A. Am. J. Bariatr. Med., 1993, 17-19.
108. Thom, E. Int. J. Obes., 1996, 20(Suppl. 4), 48.
109. Heymsfield, S.B., Allison, D.B., Vasselli, J.R., Pietrobelli, A., Greenfield, D., Nunez, C. JAMA. 1998, 280(18), 1596-600.
110. Mattes, R.D., Bormann, L. Physiol. Behav., 2000, 71(1-2), 87-94.
111. Westerterp-Plantenga, M.S., Kovacs, E.M. Int. J. Obes. Relat. Metab. Disord., 2002, 26(6), 870-2.
112. Lim, K., Ryu, S., Ohishi, Y., Watanabe, I., Tomi, H., Suh, H., Lee, W.K., Kwon, T. J. Nutr. Sci. Vitaminol. (Tokyo), 2002 48(2), 128-33.
113. van Loon, L.J., van Rooijen, J.J., Niesen, B., Verhagen, H., Saris, W.H., Wagenmakers, A.J. Am. J. Clin. Nutr., 2000, 72(6), 1445-50.
114. Jena, B.S., Jayaprakasha, G.K., Singh, R.P., Sakariah, K.K. J. Agric. Food Chem., 2002, 50(1), 10-22.
115. Clouatre,, D., Rosenbaum, M. The Diet and Health Benefits of HCA (Hydroxycitric Acid); Keats Publishing, New Cannan, C.T, 1994.
116. Stryer, L. Biochemistry, New York, NY, Freeman, 1988
117. Stanko, R.T., Mullick, P., Clarke, M.R., Contis, L.C., Janosky, J.E., Ramasastry, S.S. Cancer Res., 1994, 54(4 1004-7.
118. Stanko, R.T., Sekas, G., Isaacson, I.A., Clarke, M.R., Billiar, T.R., Paul, H.S. Metabolism, 1995, 44(2), 166-71.
119. Cicalese, L., Lee, K., Schraut, W., Watkins, S., Borle, A., Stanko, R. Am. J. Surg., 1996, 171(1), 97-100; discussion 100-1.
120. Kalman, D., Colker, C.M., Wilets, I., Roufs, J.B., Antonio, J. Nutrition, 1999, 15(5), 337-40.
121. Stanko, R.T., Reynolds, H.R., Hoyson, R., Janosky, J.E., Wolf, R. Am. J. Clin. Nutr., 1994, 59(2), 423-7.
122. Stanko, R.T., Arch, J.E. Int. J. Obes. Relat. Metab. Disord., 1996, 20(10), 925-30.
123. Kalman, D., Roufs, J and Maharam, L.G. Med. Sci. Sports Exerc., 1998, 30, S156,
124. Morrison, M.A., Spriet, L.L., Dyck, D.J. J. Appl. Physiol. 2000, 89(2), 549-56.
125. Guidance for the clinical evaluation of weight control drugs (Sept. 24, 1996), Division of Metabolic and Endocrine Drug Products, Food and Drug Administration.
126. Guidance on clinical investigation of drugs used in weight control (Dec. 17, 1997), Committee for Proprietary Medicinal Products (CPMP), European Agency for the Evaluation of Medicinal Products (EMEA), CPMP/ EWP/ 281/ 96.
127. Reductil [package insert]. Abbott Park, III, Abbott Laboratories; 2000.
128. Heal, D.J., Frankland, A.T., Gosden, J., Hutchins, L.J., Prow, M.R., Luscombe, G.P., Buckett, W.R.. Psychopharmacology, 1992, 107, 303-309.
129. Cole, J.O., Levin, A., Beake, B., Kaiser, P.E., Scheinbaum, M.L. J. Clin. Psychopharmacol.,1998, 18, 231-236.
130. Bray, G.A., Blackburn, G.L., Ferguson, J.M., Greenway, F.L., Jain, A.K., Mendel, C.M., Mendels, J., Ryan, D.H., Schwartz, S.L., Scheinbaum, M.L., Seaton, T.B. Obes. Res., 1999, 7, 189-198.
131. Rolls, B.J., Shide, D.J., Thorwart, M.L., Ulbrecht, J.S. Obes. Res., 1998, 6, 1-11.
132. Hansen, D.L., Toubro, S., Stock, M.J., Macdonald, I.A., Astrup, A. Am. J. Clin. Nutr., 1998, 68, 1180-1186.
133. Seagle, H.M., Bessesen, D.H., Hill, J.O. Obes. Res., 1998, 6, 115-121.
134. Bray, G.A., Blackburn, G.L., Ferguson, J.M., Greenway, F.L., Jain, A.K., Mendel, C.M., Mendels, J., Ryan, D.H., Schwartz, S.L., Scheinbaum, M.L., Seaton, T.B. Obes. Res., 1999, 7, 189-198.
135. Van Gaal, L.E., Wauters, M.A., Peiffer, F.W., De Leeuw, I.H. Int. J. Obes. Relat. Metab. Disord., 1998, 22(Suppl 1 , S38-S40.
136. Fujioka, K., Seaton, T.B., Rowe, E., Jelinek, C.A., Raskin, P., Lebovitz, H.E., Weinstein, S.P. Diabetes Obes. Metab., 2000 2, 175-187.
137. McMahon, F.G., Fujioka, K., Singh, B.N., Mendel, C.M., Rowe, E., Rolston, K., Johnson, F., Mooradian, A.D. Arch. Intern. Med., 2000, 160, 2185-2191.
138. Dujovne, C.A., Zavoral, J.H., Rowe, E., Mendel, C.M. Am. Heart J., 2001, 142, 489-497.
139. James, W.P., Astrup, A., Finer, N., Hilsted, J., Kopelman, P., Rossner, S., Saris, W.H., Van Gaal, L.F. Lancet, 2000, 356, 2119-2125.
140. Bach, D.S., Rissanen, A.M., Mendel, C.M., Shepherd, G., Weinstein, S.P., Kelly, F., Seaton, T.B., Patel, B., Pekkarinen, T.A., Armstrong, W.F. Obes. Res., 1999, 7, 363-369.
141. Weissman, N.J. Am. J. Med. Sci., 2001, 21, 285-291.
142. Gardin, J.M., Schumacher, D., Constantine, G., Davis, K.D., Leung, C., Reid, C.L. JAMA, 2000, 283, 1703-1709.
143. Press release (Jun. 27, 2002), Committee for Proprietary Medicinal Products (CPMP), European Agency for the Evaluation of Medicinal Products (EMEA), EMEA/ CPMP/ 3065/ 02.
144. Guerciolini, R., Int. J. Obes. Relat. Metab. Disord., 1997, 21(Suppl. 3), S12-S23.
145. Zhi, J., Melia, A.T., Eggers, H., Joly, R., Patel, I.H. J. Clin. Pharmacol., 1995, 35, 1103-1108.
146. Sjostrom. L., Rissanen, A., Andersen, T., Boldrin, M., Golay, A., Koppeschaar, H.P., Krempf, M. Lancet, 1998, 352, 167-172.
147. Davidson, M.H., Hauptman, J., DiGirolamo, M., Foreyt, J.P., Halsted, C.H., Heber, D., Heimburger, D.C., Lucas, C.P., Robbins, D.C., Chung, J., Heymsfield, S.B. JAMA, 1999, 281, 235-242.
148. Torgerson, J.S., Hauptman, J., Boldrin, M.N., Sjostrom, L. Diabetes Care, 2004, 27(1), 155-61.
149. Muls, E., Kolanowski, J., Scheen, A., Van Gaal, L. Int. J. Obes. Relat. Metab. Disord., 2001, 25, 1713-1721.
150. Canovatchel, W. Long-term tolerability profile of orlistat, an intestinal lipase inhibitor [abstract]. Presented at, the 16th International Diabetes Federation Congress; July 20-25, 1997; Helsinki, Finland.
151. McDuffie, J.R., Calis, K.A., Booth, S.L., Uwaifo, G.I., Yanovski, J.A. Pharmacotherapy, 2002, 22(7), 814-22.
152. Nagele, H., Petersen, B., Bonacker, U., Rodiger, W. Eur. J. Clin. Pharmaco., 1999, 55, 667-669.
153. Colman, E., Fossler, M. N. Engl. J. Med., 2000, 342, 1141-1142.
154. Wadden, T.A., Berkowitz, R.I., Womble, L.G., Sarwer, D.B., Arnold, M.E., Steinberg, C.M. Obes. Res., 2000, 8, 431-437.
155. Drenick, E.J., Bale, G.S., Seltzer, F., Johnson, D.G. JAMA 1980, 243(5), 443-5.
156. Fobi, M.A. J. Natl. Med. Assoc., 2004, 96(1) 61-75.
157. Pinkney, J., Kerrigan, D. Obes. Rev., 2004, 5(1), 69-78.
158. Kremen, A.J., Linner, J.H., Nelson, C.H. Ann. Surg., 1954, 140(3), 439-48.
159. Scopinaro, N., Gianetta, E., Adami, G.F., Friedman, D., Traverso, E., Marinari, G.M., Cuneo, S., Vitale, B., Ballari, F., Colombini, M., Baschieri, G., Bachi, V. Surgery, 1996, 119(3), 261-8.
160. Hess, D.S., Hess, D.W. Obes. Surg., 1998, 8(3) 267-82.
161. Mason, E.E., Ito, C. Surg. Clin. North Am., 1967, 47(6), 1345-51.
162. Hess, D.S., Hess, D.W. Obes. Surg., 1998, 8 267 Π282.
163. Ren, C.J., Patterson, E., Gagner, M. Obes. Surg., 2000, 10, 514 Π523.
164. Griffen, W.O., Young, V.L. and Stevenson, C.C. Ann. Surg. 1977, 186, pp. 500-509.
165. Kuzmak, L.I., Yap, I.S., McGuire, L., Dixon, J.S., Young, M.P. AORN J. 1990 51(5), 1307-24.
166. Committee on Emerging Surgical Technology and Education, American College of Surgeons. Recommendations for facilities performing bariatric surgery. Bull Am. Coll. Surg., 2000, 85(9 , 20 Π23.
167. Van Hout, G.C., Leibbrandt, A.J., Jakimowicz, J.J., Smulders, J.F., Schoon, E.J., Van Spreeuwel, J.P., Van Heck, G.L. Obes. Surg. 2003, 13(6), 926-31.
168. Kral, J.G. Int. J. Obes. Relat. Metab. Disord., 2001 25 Suppl 1, S107-12.
169. Chevallier, J.M., Zinzindohoue, F., Elian, N. Obes. Surg. 2002, 12, 93 Π99.
170. Fielding, G.A., Rhodes, M., Nathanson, L.K. Surg. Endosc. 1999; 13, 550 Π554.
171. DeMaria, E.J., Sugerman, H.J., Meador, J.G. Ann. Surg., 2001, 233(6), 809 Π818.
172. Gillies, P.J. J. Am. Diet Assoc., 2003, 103(12) Suppl. 2), S50-5.
173. Reaven, G.M. Curr. Atheroscler. Rep., 2000, 2(6), 503-7.
174. Reaven, G.M. Curr. Opin. Lipidol., 1997, 8(1) 23-7.
175. McCarty, M.F. Med. Hypotheses, 1998, 51(6), 451-64.
176. Hamazaki, K., Itomura, M., Huan, M., Nishizawa, H., Watanabe, S., Hamazaki, T., Sawazaki, S., Terasawa, K., Nakajima, S., Terano, T., Hata, Y., Fujishiro, S. Lipids, 2003, 38(4), 353-8.
177. Grimsgaard, S., Bonaa, K.H., Hansen, J.B., Nordoy, A. Am. J. Clin. Nutr., 1997, 66(3), 649-59.
178. Larimore, W.L., O'Mathuna, D.P. Ann. Pharmacother., 2003, 37(6), 893-8.