Effects of leptin on gonadotropin-releasing hormone release from hypothalamic-infundibular explants and gonadotropin release from adenohypophyseal primary cell cultures: Further evidence that fully nourished cattle are resistant to leptin

Animal Reproduction Science

Volumn 85, Issue 1-2, 2005, Pages 41-52

  Amstalden, M ^a,b   Harms, P G ^b   Welsh Jr , T H ^b   Randel, R D ^c   Williams, G L ^a,b  

^a 78102 9410   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c Texas AandM Univ Agric Res E   (United States)

Author keywords

Bovine; Follicle stimulating hormone; Gonadotropin releasing hormone; Leptin; Luteinizing hormone

Indexed keywords

FOLLITROPIN; FORSKOLIN; GONADORELIN; GONADOTROPIN; LEPTIN; LUTEINIZING HORMONE; PHORBOL 13 ACETATE 12 MYRISTATE;

ADENOHYPOPHYSIS; ANIMAL; ARTICLE; CATTLE; CELL CULTURE; DRUG EFFECT; DRUG RESISTANCE; HYPOTHALAMUS; MALE; NEUROHYPOPHYSIS; PHYSIOLOGY; SECRETION;

ANIMALS; CATTLE; CELLS, CULTURED; DRUG RESISTANCE; FOLLICLE STIMULATING HORMONE; FORSKOLIN; GONADOTROPIN-RELEASING HORMONE; GONADOTROPINS; HYPOTHALAMUS; LEPTIN; LUTEINIZING HORMONE; MALE; PITUITARY GLAND, ANTERIOR; PITUITARY GLAND, POSTERIOR; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA; BOS TAURUS; BOVINAE; OVIS; RODENTIA; SUS SCROFA;

EID: 8844256220     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2004.03.003     Document Type: Article

References (44)

1. Ahima R.S., Dushay J., Flier S.N., Prabakaran D., Flier J.S. Leptin accelerates the onset of puberty in normal female mice. J. Clin. Invest. 99:1997;391-395
2. Ahima R.S., Saper C.B., Flier J.S., Elmquist J.K. Leptin regulation of neuroendocrine systems. Front. Neuroendocrinol. 21:2000;263-307
3. Amstalden M., Garcia M.R., Stanko R.L., Nizielski S.E., Morrison C.D., Keisler D.H., Williams G.L. Central infusion of recombinant ovine leptin normalizes plasma insulin and stimulates a novel hypersecretion of luteinizing hormone after short-term fasting in mature beef cows. Biol. Reprod. 66:2002;1555-1561
4. Amstalden M., Zieba D.A., Edwards J.F., Harms P.G., Welsh T.H. Jr., Stanko R.L., Williams G.L. Leptin acts at the bovine adenohypophysis to enhance basal and GnRH-mediated release of LH: differential effects are dependent upon nutritional history. Biol. Reprod. 69:2003;1539-1544
5. Amstalden M., Zieba D.A., Garcia M.R., Stanko R.L., Welsh T.H. Jr., Hansel W.H., Williams G.L. Evidence that lamprey gonadotropin-releasing hormone-III does not release follicle-stimulating hormone selectively in cattle. Reproduction. 127:2004;35-43
6. Barash I.A., Cheung C.C., Weigle D.S., Ren H., Kabigting E.B., Kuijer J.L., Clifton D.K., Steiner R.A. Leptin is a metabolic signal to the reproductive system. Endocrinology. 137:1996;3144-3147
7. Barb C.R., Barrett J.B., Kraeling R.R., Rampacek G.B. Role of leptin in modulating neuroendocrine function: a metabolic link between the brain-pituitary and adipose tissue. Reprod. Dom. Anim. 34:1999;111-125
8. Bjorbaek C., El-Haschimi K., Frantz J.D., Flier J.S. The role of SOCS-3 in leptin signaling and leptin resistance. J. Biol. Chem. 274:1999;30059-30065
9. Bjorbaek C., Elmquist J.K., Frantz J.D., Shoelson S.E., Flier J.S. Identification of SOCS-3 as a potential mediator of central leptin resistance. Mol. Cell. 1:1998;619-625
10. Caro J.F., Kolaczynski J.W., Nyce M.R., Ohannesian J.P., Opentanova I., Goldman W.H., Lynn R.B., Zhang P.L., Sinha M.K., Considine R.V. Decreased cerebrospinal-fluid/serum leptin ration in obesity: a possible mechanism for leptin resistance. Lancet. 348:1996;159-161
11. Considine R.V., Sinha M.K., Heiman M.L., Kriauciunas A., Stephens T.W., Nyce M.R., Ohannesian J.P., Marco C.C., McKee L.J., Bauer T.L., Caro J.F. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New Engl. J. Med. 334:1996;292-295
12. De Biasi S.N., Apfelbaum L.I., Apfelbaum M.E. In vitro effect of leptin on LH release by anterior pituitary glands from female rats at the time of spontaneous and steroid-induced LH surge. Eur. J. Endocrinol. 145:2001;659-665
13. Dippel W.W., Chen P.L., McArthur N.H., Harms P.G. Calcium involvement in luteinizing hormone-releasing hormone release from the bovine infundibulum. Dom. Anim. Endocrinol. 12:1995;349-354
14. Dyer C.J., Simmons J.M., Matteri R.L., Keisler D.H. Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissues and is differentially expressed in hypothalamic regions of well-fed and feed-restricted ewes. Domest. Anim. Endocrinol. 14:1997;119-128
15. Emilsson V., Arch J.R., de Groot R.P., Lister C.A., Cawthorne M.A. Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues. FEBS Lett. 455:1999;170-174
16. Gertler A., Simmons J.M., Keisler D.H. Large-scale preparation of biologically-active recombinant ovine obese protein (leptin). FEBS Lett. 422:1998;137-140
17. Halaas J.L., Boozer C., Blair-West J., Fidahusein N., Denton D.A., Friedman J.M. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc. Natl. Acad. Sci. 94:1997;8878-8883
18. Henry B.A., Goding J.W., Alexander W.S., Tilbrook A.J., Canny B.J., Dunshea F., Rao A., Mansell A., Clarke I.J. Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function. Endocrinology. 140:1999;1175-1182
19. Henry B.A., Goding J.W., Tilbrook A.J., Dunshea F.R., Clarke I.J. Intracerebroventricular infusion of leptin elevates the secretion of luteinising hormone without affecting food intake in long-term food-restricted sheep, but increases growth hormone irrespective of bodyweight. J. Endocrinol. 168:2001;67-77
20. I'Anson H., Manning J.M., Herbosa C.G., Pelt J., Friedman D.R., Wood R.I., Bucholtz D.C., Foster D.L. Central inhibition of goandotropin-releasing hormone secretion in the growth-restricted hypogonadotropic female sheep. Endocrinology. 141:2000;520-527
21. Iqbal J., Pompolo S., Considine R.V., Clarke I.J. Localization of leptin receptor-like immunoreactivity in the corticotropes, somatotropes, and gonadotropes in the ovine anterior pituitary. Endocrinology. 141:2000;1515-1520
22. Keisler D.H., Lucy M.C. Perception and interpretation of the effects of undernutrition on reproduction. J. Anim. Sci. 74(Suppl 3):1996;1-17
23. Kile J.P., Alexander B.M., Moss G.E., Hallford D.M., Nett T.M. Gonadotropin-releasing hormone overrides the negative effect of reduced dietary energy on gonadotropin synthesis and secretion in ewes. Endocrinology. 128:1991;843-849
24. Lin J., Barb C.R., Matteri R.L., Kraeling R.R., Chen X., Meinersmann R.J., Rampacek G.B. Long form leptin receptor mRNA expression in the brain, pituitary, and other tissues in the pig. Domest. Anim. Endocrinol. 19:2001;53-61
25. Maciel, M.N., Zieba, D.A., Amstalden, M., Keisler, D.H., Neves, J., Williams, G.L., 2004a. Chronic administration of recombinant ovine leptin in growing beef heifers: effects on secretion of LH, metabolic hormones, and timing of puberty. J. Anim. Sci. (in press).
26. Maciel M.N., Zieba D.A., Amstalden M., Keisler D.H., Neves J., Williams G.L. Leptin prevents fasting-mediated reductions in pulsatile secretion of luteinizing hormone and enhances its gonadotropin-releasing hormone-mediated release in heifers. Biol. Reprod. 70:2004;229-235
27. Martin R.L., Perez E., He Y.J., Dawson R. Jr., Millard W.J. Leptin resistance is associated with hypothalamic leptin receptor mRNA and protein downregulation. Metabolism. 49:2000;1479-1484
28. McVey W.R. Jr., Williams G.L. Mechanical masking of neurosensory pathways at the calf-teat interface: endocrine, reproductive, and lactational features of the suckled anestrous cow. Theriogenology. 35:1991;931-941
29. Morrison C.D., Daniel J.A., Holmberg B.J., Djiane J., Raver N., Gertler A., Keisler D.H. Central infusion of leptin into well-fed and undernourished ewe lambs: effects on feed intake and serum concentrations of growth hormone and luteinizing hormone. J. Endocrinol. 168:2001;317-324
30. Morrison C.D., Wood R., McFadin E.L., Whitley N.C., Keisler D.H. Effect of intravenous infusion of recombinant ovine leptin on feed intake and serum concentrations of GH, LH, insulin, IGF-I, cortisol, and thyroxine in growing prepubertal ewe lambs. Domest. Anim. Endocrinol. 22:2002;103-112
31. Nagatani S., Guthikonda P., Thompson R.C., Tsukamura H., Maeda K-I., Foster D.L. Evidence for GnRH regulation by leptin: leptin administration prevents reduced pulsatile LH secretion during fasting. Neuroendocrinology. 67:1998;370-376
32. Nagatani S., Zeng Y., Keisler D.H., Foster D.L., Jaffe C.A. Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in sheep. Endocrinology. 141:2000;3965-3975
33. Ogura K., Irahara M., Kiyokawa M., Tezuka M., Matsuzaki T., Yasui T., Kamada M., Aono T. Effects of leptin on secretion of LH and FSH from primary cultured female rat pituitary cells. Eur. J. Endocrinol. 144:2001;653-658
34. Scarpace P.J., Matheny M., Tumer N. Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats. Neuroscience. 104:2001;1111-1117
35. Tanner J.W., Davis S.K., McArthur N.H., French J.T., Welsh T.H. Jr. Modulation of growth hormone (GH) secretion and GH mRNA levels by GH-releasing factor, somatostatin and secretagogues in cultured bovine adenohypophyseal cells. J. Endocrinol. 125:1990;109-115
36. Wade G.N., Schneider J.E., Li H.Y. Control of fertility by metabolic cues. Am. J. Physiol. 270:1996;E1-19
37. Watanobe H. Leptin directly acts within the hypothalamus to stimulate gonadotropin-releasing hormone secretion in vivo in rats. J. Physiol. 545:2002;255-268
38. Waters W.W., Chen P.L., McArthur N.H., Moreno P.A., Harms P.G. Calcium/Calmodulin-dependent protein kinase II involvement in releasing of gonadotropin-releasing hormone. Neuroendocrinology. 67:1998;145-152
39. Welsh, T.H. Jr., Harms, P.G., McArthur, N.H., Procknor, M., 1986. Regulation of adenohypophyseal hormones by hypothalamic neurohormones and activators of adenyl cylase and protein kinase C. In: Goheen, S. (Ed.), Membrane Proteins. Proc. First Membrane Protein Symposium, Bio-Rad Laboratories Publishers, San Diego, CA, USA, pp. 703-713.
40. Widdowson P.S., Upton R., Buckingham R., Arch J., Williams G. Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity. Diabetes. 46:1997;1782-1785
41. Woller M., Tessmer S., Neff D., Nquema A.A., Roo B.V., Waechter-Brulla D. Leptin stimulates gonadotropin releasing hormone release from cultured intact hemihypothalami and enxymatically dispersed neurons. Exp. Biol. Med. 226:2001;591-596
42. Yu W.H., Kimura M., Walczewska A., Karanth S., McCann S.M. Role of leptin in hypothalamic-pituitary functionm. Proc. Natl. Acad. Sci. USA. 94:1997;1023-1028
43. Zamorano P.L., Mahesh V.B., De Sevilla L.M., Chorich L.P., Bhat G.K., Brann D.W. Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat. Neuroendocrinology. 65:1997;223-228
44. Zieba D.A., Amstalden M., Maciel M.N., Keisler D.H., Raver N., Gertler A., Williams G.L. Divergent effects of leptin on luteinizing hormone and insulin secretion are dose dependent. Exp. Biol. Med. 228:2003;325-330