Intracerebroventricular infusion of leptin elevates the secretion of luteinising hormone without affecting food intake in long-term food-restricted sheep, but increases growth hormone irrespective of bodyweight

Journal of Endocrinology

Volumn 168, Issue 1, 2001, Pages 67-77

  Henry, B A ^a   Goding, J W ^a   Tilbrook, A J ^a   Dunshea, F R ^a   Clarke, I J ^a  

^a MONASH UNIVERSITY MEDICAL SCHOOL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GROWTH HORMONE; INSULIN; LEPTIN; LUTEINIZING HORMONE; TRIACYLGLYCEROL; UREA;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; FOOD INTAKE; GROWTH HORMONE RELEASE; LUTEINIZING HORMONE RELEASE; METABOLIC RATE; NEUROENDOCRINOLOGY; NONHUMAN; PRIORITY JOURNAL; SATIETY;

ANALYSIS OF VARIANCE; ANIMALS; CHRONIC DISEASE; CROSS-OVER STUDIES; FATTY ACIDS, NONESTERIFIED; FEMALE; FOLLICLE STIMULATING HORMONE; GROWTH HORMONE; INJECTIONS, INTRAVENTRICULAR; LEPTIN; LUTEINIZING HORMONE; NUTRITION DISORDERS; OVARIECTOMY; SATIETY RESPONSE; SHEEP;

EID: 0035143571     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1680067     Document Type: Article

References (49)

1. Effect of chronic food restriction on pulsatile luteinizing hormone secretion and hypothalamic neuropeptide Y gene expression in castrated male sheep
2. Role of leptin in the neuroendocrine response to fasting
3. Leptin regulation of neuroendocrine systems
4. Control of feed intake and regulation of energy balance in ruminants
5. Recombinant porcine leptin reduces feed intake and stimulates growth hormone secretion in swine
6. Increased galanin and neuropeptide-Y immunoreactivity within the hypothalamus of ovariectomised ewes following a prolonged period of reduced body weight is associated with changes in plasma growth hormone but not gonadotropin levels
7. The role of neuropeptide Y (NPY) in the control of LH secretion in the ewe with respect to season, NPY receptor subtype and the site of action in the hypothalamus
8. Effects of obesity on insulin sensitivity and responsiveness in sheep
9. Feedback effects of the testis on pituitary responsiveness to luteinizing hormone-releasing hormone infusions in the ram
10. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
11. Obese (oh) gene defects are rare in human obesity
12. Regulation of in vivo growth hormone secretion by leptin
13. Role of growth hormone (GH)-releasing hormone and somatostatin on leptin-induced GH secretion
14. Variable patterns of gonadotropin-releasing hormone secretion during the estrogen-induced luteinizing hormone surge in ovariectomized ewes
15. Seasonal changes in the expression of neuropeptide Y and pro-opiomelanocortin mRNA in the arcuate nucleus of the ovariectomised ewe; relationship to the seasonal appetite and breeding cycles
16. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
17. Episodic growth hormone secretion in sheep in relation to time of feeding, spontaneous meals and short term fasting
18. Effects of recombinant leptin therapy in a child with congenita leptin deficiency
19. The stimulatory effect of leptin on the neuroendocrine reproductive axis of the monkey
20. Effect of restricted nutrition on puberty in the lamb: Patterns of tonic luteinizing hormone (LH) secretion and competency of the LH surge system
21. Metabolic interfaces between growth and reproduction. I. Nutritional modulation of gonadotropin, prolactin and growth hormone secretion in the growth-limited female lamb
22. Stimulatory effect of melanin-concentrating hormone on luteinising hormone release
23. Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus
24. Weight-reducing effects of the plasma protein encoded by the obese gene
25. Central administration of leptin to ovariectomised ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland; evidence for a dissociation of effects on appetite and neuroendocrine function
26. Long-term alterations in adiposity affect the expression of melanin-concentrating hormone and enkephalin but not proopiomelanocortin in the hypothalamus of ovariectomized ewes
27. Localization of leptin receptor-like immunoreactivity in the corticotropes, somatotropes, and gonadotropes in the ovine anterior pituitary
28. Neuroendocrine consequences of fasting in adult male macaques: Effects of recombinant rhesus macaque leptin infusion
29. Abnormal splicing of the leptin receptor in diabetic mice
30. Regulation of gonadotrophin secretion in rams from birth to sexual maturity. I. Plasma LH, FSH and testosterone levels
31. Leptin prevents fasting-induced suppression of prothyrotropinreleasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
32. Dynamic and static phases of severe dietary obesity in sheep: Food intakes, endocrinology and carcass and organ chemical composition
33. Influence of food restriction on neuropeptide-Y, proopiomelanocortin, and luteinizing hormone-releasing hormone gene expression in sheep hypothalami
34. Absence of mutations in the human OB gene in obese/diabetic subjects
35. Congenital leptin deficiency is associated with severe earlyonset obesity in humans
36. Melanin-concentrating hormone, melanocortin receptors and regulation of luteinizing hormone release
37. Evidence for GnRH regulation by leptin: Leptin administration prevents reduced pulsatile LH secretion during fasting
38. Human obese gene: Molecular screening in Japanese and Asian Indian NIDDM patients associated with obesity
39. Lupin and cowpea supplements for growth, wool production and reproduction in rams
40. Orexins, a novel family of hypothalamic neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner
41. The in vitro effect of leptin on basal and growth hormone-releasing hormone-stimulated growth hormone secretion from the ovine pituitary gland
42. Somatotropin in lactating cows: Effect on response to epinephrine and insulin
43. A leptin missense mutation associated with hypogonadism and morbid obesity
44. Orexins, orexigenic hypothalamic neuropeptides, suppress the pulsatile secretion of luteinizing hormone in ovariectomized female rats
45. Leptin is a potent stimulator of spontaneous pulsatile growth hormone (GH) secretion and the GH response to GH-releasing hormone
46. Effect of restricted feeding on the concentrations of growth hormone (GH), gonadotropins, and prolactin (PRL) in plasma, and on the amounts of messenger ribonucleic acid for GH, gonadotropin subunits, and PRL in the pituitary glands of adult ovariectomized ewes
47. Intracerebroventricular administration of melanin-concentrating hormone suppresses pulsatile luteinizing hormone release in the female rat
48. Evidence for a leptin-neuropeptide Y axis for the regulation of growth hormone secretion in the rat
49. Positional cloning of the mouse obese gene and its human homologue