Methods to assess tissue-specific distribution and metabolism of drugs

Current Drug Metabolism

Volumn 5, Issue 6, 2004, Pages 463-481

  Langer, Oliver ^a   Müller, Markus ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Clinical; Drug development; Magnetic resonance spectroscopy; Microdialysis; Microdosing; Pharmacokinetics; Positron emission tomography; Tissue distribution

Indexed keywords

5 ETHYNYLURACIL; 5 FLUORO 3 [3 [4 (5 METHOXY 4 PYRIMIDINYL) 1 PIPERAZINYL]PROPYL] 1H INDOLE; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CAPECITABINE; CARMUSTINE; CEFACLOR; CEFODIZIME; CEFPIROME; CIPROFLOXACIN; CISPLATIN; ERYTHROMYCIN; FLEROXACIN; FLUCONAZOLE; FLUOROURACIL; FLUVOXAMINE; GLYCOPROTEIN P; LOMEFLOXACIN; MOXIFLOXACIN; N (2 DIMETHYLAMINOETHYL) 4 ACRIDINECARBOXAMIDE; NORFLOXACIN; PEFLOXACIN; ROBALZOTAN; TEMOZOLOMIDE; TRIAMCINOLONE ACETONIDE; TROVAFLOXACIN; UNINDEXED DRUG; VINPOCETINE; XR 5000; ZANAMIVIR;

AREA UNDER THE CURVE; BLOOD BRAIN BARRIER; BRAIN CANCER; CLINICAL TRIAL; COLORECTAL CANCER; DIGESTIVE SYSTEM CANCER; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG PENETRATION; DRUG STRUCTURE; DRUG TARGETING; DRUG TISSUE LEVEL; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; LIVER METABOLISM; LIVER METASTASIS; MICRODIALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; DRUG MONITORING; HUMANS; ORGAN SPECIFICITY; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; TECHNOLOGY, PHARMACEUTICAL; TISSUE DISTRIBUTION;

EID: 8844242556     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389200043335379     Document Type: Review

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