Pharmacokinetics of radiolabelled anticancer drugs for positron emission tomography

Current Pharmaceutical Design

Volumn 9, Issue 11, 2003, Pages 917-929

  Hutchinson, O Clyde ^a   Collingridge, David R ^a   Barthel, Henryk ^a   Price, Pat M ^a   Aboagye, Eric O ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 ETHYNYLURACIL; ANTINEOPLASTIC AGENT; CARBON 11; COPPER 62; COPPER 64; FLUORINE 18; FLUORODEOXYGLUCOSE F 18; FLUOROURACIL; FOLINIC ACID; GALLIUM 68; IODINE 124; IRON 52; METHYL IODIDE; MITOZOLOMIDE; N (2 DIMETHYLAMINOETHYL) 4 ACRIDINECARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 2 PYRIDYLQUINOLINE 8 CARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 9 METHOXYPHENAZINE 1 CARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL]DIBENZO 1,4 DIOXIN 1 CARBOXAMIDE; NEW DRUG; NITROGEN 13; OXYGEN 15; PHENAZINE DERIVATIVE; QUINOLINE DERIVATIVE; RADIOISOTOPE; RUBIDIUM 82; SN 23490; SN 23719; SN 23935; TEMOZOLOMIDE; TRACER; TRIFLUOROMETHANESULFONIC ACID METHYL ESTER C 11; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIRCONIUM;

ANTINEOPLASTIC ACTIVITY; BONE MARROW SUPPRESSION; BRAIN TUMOR; CHILDHOOD CANCER; COLON TUMOR; DIGESTIVE SYSTEM CANCER; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DNA BINDING; DRUG HALF LIFE; DRUG METABOLISM; DRUG MONITORING; DRUG POTENTIATION; DRUG RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TISSUE LEVEL; GLIOMA; HUMAN; ISOTOPE LABELING; LEUKEMIA; LEWIS CARCINOMA; MATHEMATICAL MODEL; MELANOMA; NEUROTOXICITY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

ACRIDINES; ANIMALS; ANTINEOPLASTIC AGENTS; DACARBAZINE; FLUOROURACIL; HUMANS; MOLECULAR STRUCTURE; RADIOACTIVE TRACERS; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037241480     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612033455288     Document Type: Review

References (80)

1. Saleem, A., Harte, R.J., Matthews, J.C., Osman, S., Brady, F., Luthra, S.K., Brown, G.D., Bleehen, N., Connors, T., Jones, T., Price, P.M., Aboagye, E.O. J. Clin. Oncol., 2001, 19(5), 1421-9.
2. Brady, F., Luthra, S.K., Tochon-Danguy, H.J., Steel, C.J., Waters, S.L., Kensett, M.J., Landais, P., Shah, F., Jaeggi, K.A., Drake, A., Clarke, J.C., Pike, V.W. Int. J. Rad. Appl. Instrum. [A], 1991, 42(7), 621-8.
3. Atwell, G.J., Rewcastle, G.W., Baguley, B.C., Denny, W.A. J. Med. Chem., 1987, 30(4), 664-9.
4. Finlay, G.J., Marshall, E., Matthews, J.H., Paull, K.D., Baguley, B.C. Cancer Chemother. Pharmacol., 1993, 31(5), 401-6.
5. Baguley, B.C., Holdaway, K.M., Fray, L.M. J. Natl. Cancer Inst., 1990, 82(5), 398-402.
6. Baguley, B.C., Finlay, G.J., Ching, L.M. Oncol. Res., 1992, 4(7), 267-74.
7. Finlay, G.J., Baguley, B.C. Eur. J. Cancer Clin. Oncol., 1989, 25(2), 271-7.
8. McCrystal, M.R., Evans B.D., Harvey, V.J., Thompson, P.I., Porter, D.J., Baguley, B.C. Cancer Chemother. Pharmacol., 1999, 44(1), 39-44.
9. Twelves, C.J., Gardner, C., Flavin, A., Sludden, J., Dennis, L, de Bono, J., Beale, P., Vasey, P., Hutchison, C., Macham, M.A., Rodriguez, A., Judson, I., Bleehen, N.M. Br. J. Cancer, 1999, 80(11), 1786-91.
10. Cornford, E.M., Young, D., Paxton, J.W. Cancer Chemother. Pharmacol., 1992, 29(6), 439-44.
11. Osman, S., Luthra, S.K., Brady, F., Hume, S.P., Brown, G., Harte, R.J., Matthews, J.C., Denny, W.A., Baguley, B.C., Jones, T., Price, P.M. Cancer Res., 1997, 57(11), 2172-80.
12. Paxton, J.W., Young, D., Evans, S.M., Kestell, P., Robertson, I.G., Cornford, E.M. Cancer Chemother. Pharmacol., 1992, 29(5), 379-84.
13. Wilson, W.R., Denny, W.A. Academic Press, NY, 1992, Vol. 2, pp796-801.
14. Harte, R.J.A., Tilsley, D.W.0,; O'Reilly, S.M., Byrne, H., Cunningham, V., Osman, S., Luthra, S.K., Brown, G., Brady, F., Baguley, B., Denny, W., Connors, T., Jones, T., Price, P. Ann. Oncol., 1994, 5, 176.
15. Schofield, P.C., Robertson, I.G., Paxton, J.W., McCrystal, M.R., Evans, B.D. Cancer Chemother. Pharmacol., 1999, 44(1), 51-8.
16. Meikle, S.R., Matthews, J.C., Brock, C.S., Wells, P., Harte, R.J., Cunningham, V.J., Jones, T., Price, P. Cancer Chemother. Pharmacol., 1998, 42(3), 183-93.
17. Rewcastle, G.W., Denny, W.A., Baguley, B.C. J. Med. Chem., 1987, 30, 843-851.
18. Atwell, G.J., Baguley, B.C., Denny, W.A. J. Med. Chem., 1989, 32, 396-401.
19. Lee, H.H., Palmer, B.D., Boyd, M., Baguley, B.C., Denny, W.A. Potential J. Med. Chem., 1992, 35, 196-198.
20. Brown, G., Brady, F., Luthra, S.K., Osman, S., Gamage, S., Denny, W.A., Baguley, B.C., Waters, S.L., Price, P.M. J. Label Compd. Radiopharm., 1996, 37, 196-8.
21. Osman, S., Rowlinson-Busza, G., Luthra, S.K., Brown, G., Brady, F., Gamage, S.A., Denny, W.A., Baguley, B.C., Price, P.M. J. Label Compd. Radiapharm., 1999, 42, S270-S272.
22. Mizuno, N.S., Decker, R.W. Biochem. Pharmacol., 1976, 25(23), 2643-7.
23. Stevens, M.F., Newlands, E.S. Eur. J. Cancer, 1993, 7(7), 1045-7.
24. Stevens, M.F., Hickman, J.A., Langdon, S.P., Chubb, D., Vickers, L., Stone, R., Baig, G., Goddard, C., Gibson, N.W., Slack, J.A. Cancer Res., 1987, 47, 5846-5852.
25. Stevens, M.F., Hickman, J.A., Stone, R., Gibson, N.W., Baig, G.U., Lunt, E., Newton, C.G. J. Med. Chem., 1984, 27, 196-201.
26. Lunt, E., Newton, C.G., Smith, C., Stevens, G.P., Stevens, M.F., Straw, C.G., Walsh, R.J., Warren, P.J., Fizames, C., Lavelle, F., Landdon, S.P., Vickers, L. J. Med. Chem., 1987, 30, 357-366.
27. Horspool, K.R., Stevens, M.F., Newton, C.G., Lunt, E., Walsh, R.J., Pedgrift, B.L., Baig, G.U., Lavelle, F., Fizames, C. J. Med. Chem., 1990, 33, 1393-1399.
28. Hickman, J.A., Stevens, M.F.G., Gibson, N.W. Cancer Res., 1985, 45, 3008-3013.
29. Newlands, E.S., Blackledge, G., Slack, J.A., Goddard, C., Brindley, C.J., Holden, L., Stevens, M.F. Cancer Treat. Rep., 1985, 69, 801-805.
30. Newlands, E.S., O'Reilly, S.M., Glaser, M.G., Bower, M., Evans, H., Brock, C., Brampton, M.H., Colquhoun, I., Lewis, P., Rice-Edwards, J.M., Illingworth, R.D., Richards, P.G. Eur. J. Cancer, 1996, 32A(13), 2236-41.
31. Bower, M., Newlands, E.S., Bleehen, N.M., Brada, M., Begent, R.J., Calvert, H., Colquhoun, i., Lewis, P., Brampton, M.H. Cancer Chemother. Pharmacol., 1997, 40(6), 484-8.
32. Brock, C.S., Newlands, E.S., Wedge, S.R., Bower, M., Evans, H., Colquhoun, I., Roddie, M., Glaser, M., Brampton, M.H., Rustin, G.J. Cancer Res., 1998, 58(19), 4363-7.
33. Bleehen, N.M., Newlands, E.S., Lee, S.M., Thatcher, N., Selby, P., Calvert, A.H., Rustin, G.J., Brampton, M., Stevens, M.F. J. Clin. Oncol., 1995, 13(4), 910-3.
34. Nicholson, H.S., Krailo, M., Ames, M.M., Seibel, N.L., Reid, J.M., Liu-Mares, W., Vezina, L.G., Ettinger, A.G., Reaman, G.H. J. Clin. Oncol., 1998, 16(9), 3037-43.
35. Estlin, E.J., Lashford, L., Ablett, S., Price, L., Gowing, R., Gholkar, A., Kohler, J., Lewis, I.J., Morland, B., Pinkerton, C.R., Stevens, M.C., Mott, M., Stevens, R., Newell, D.R., Walker, D., Dicks-Mireaux, C., McDowell, H., Reidenberg, P., Statkevich, P., Marco, A., Batra, V., Dugan, M., Pearson, A.D. Br. J. Cancer, 1998, 78(5), 652-61.
36. Woll, P.J., Crowther, D., Johnson, P.W., Soukop, M., Harper, P.G., Harris, M., Brampton, M.H., Newlands, E.S. Br. J. Cancer, 1995, 72(1), 183-4.
37. Chan, A.T., Leung, T.W., Kwan, W.H., Mok, T.S., Yeo, W., Lai, M., Johnson, P.J. Cancer Chemother. Pharmacol., 1998, 42(3), 247-9.
38. Newlands, E.S., Stevens, M.F., Wedge, S.R., Wheelhouse, R.T., Brock, C. Cancer Treat. Rev., 1997,23(1), 35-61.
39. Vaupel, P., Kallinowski, F., Okunieff, P. Cancer Res., 1989, 49(23), 6449-65.
40. Brown, G.D., Turton, D.R., Luthra, S.K., Price, P., Jones, T., Stevens, M.F.G., Baghurst, D.R., Mingos, D.M.P., Osman, S., Waters, S.L., Brady, F. J. Label Cmpd. Radiopharm., 1994, 35, 100-3.
41. Brown, G.D., Luthra, S.K., O'Reilly, S.M., Price, P., Jones, T., Stevens, M.F.G., Mingos, D.M.P., Osman, S., Brady, F. Ann. of Oncology, 1994, 5, 74.
42. Brown, G.D., Brady, F., Luthra, S.K., Prenant, C., Stevens, M.F.G., Sergis, A., Price, P. J. Label Cmpd. Radiopharm., 1998, 40, 371.
43. Osman, S., Rowlinson-Busza, G., Luthra, S.K., Brown, G.D., Brady, F., Stevens, M.F.G., Jones, T., Price, P.M. J. Label Cmpd. Radiopharm., 1997, 40, 168-169.
44. Osman, S., Rowlinson-Busza, G., Luthra, S.K., Brown, G.D., Brady, F., Ranicar, A., Stevens, M.F.G., Price, P.M. J. Label Cmpd. Radiopharm., 1999, 42, S704-S706.
45. Brock, C.S., Matthews, J.C., Brown, G., Luthra, S.K., Brady, F., Newlands, E.S., Price, P. Proceedings of Am. Soc. Clin. Oncol., 1996, 15, 475.
46. Brock, C.S., Matthews, J.C., Brown, G., Osman, S., Evans, H., Newlands, E.S., Price, P.A. Annals of Oncology, 1998, 9 (Suppl. 1), 174.
47. Saleem, A., Osman, S., Brown, G., Cunningham, V.J., Ranicar, A., Price, P., Aboagye, E. Proc. Am. Soc. Clin. Oncol., 2001, 20, 1114a
48. Grem, J. L. Semin. Oncol., 1991, 18(Suppl 1), 17-26.
49. Chen, A.P., Grem, J.L. Curr. Opin. Oncol., 1992, 4(6), 1089-98.
50. Pinedo, H.M., Peters, G.F. J. Clin. Oncol., 1988, 6(10), 1653-64.
51. Kemeny, N. Semin. Oncol., 1983, 10(2), 148-58.
52. Lavin, P., Mittelman, A., Douglass, H. Jr., Engstrom, P., Klaassen, D. Cancer, 1980, 46(7), 1536-43.
53. Richards, F., 2nd, Case, L.D., White, D.R., Muss, H.B., Spurr, C.L., Jackson, D.V., Cooper, MR., Zekan, P., Cruz, J., Stuart, J.J. J. Clin. Oncol., 1986, 4(4), 565-70.
54. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project [see comments]. J. Clin. Oncol., 1992, 10(6), 896-903.
55. Fowler, J.S., Finn, R.D., Lambrecht, R.M., Wolf, A.P. J. Nucl. Med., 1973, 14, 63-64
56. Fowler, J.S., Shiue, C-Y., Wolf, A.P., Salvadori, P.A., MacGregor, G. J. Label Compd. Radiopharm., 1982, 19, 1634-1636.
57. Diksic, M., Farrokhzad, S., Colebrook, L.D. Can. J. Chem., 1986, 64, 424-428.
58. Visser, G.W.M., Boele, S., Van Halteren, B.W., Knops, G.H.J.N., Herscheid, J.D.M., Brinkman, G.A., Hoekstra, A. J. Org. Chem., 1986, 51, 1466-1471.
59. Vine, E.N., Young, D., Vine, W.H., Wolf, W. Int. J. Appl. Radiat. Isot., 1979, 30(7), 401-5.
60. Oberdorfer, F., Hofmann, E., Maier-Borst, B.J.M. J. Label Compd. Radiopharm., 1988, 27, 137-145.
61. Visser, G.W.M., Gorree, G.C.M., Braakhuis, B.J.M., Herscheid, J.D.M. Eur. J. Nucl. Med., 1989, 15, 225-229.
62. Brown, G.D., Khan, H.R., Steel, C.J., Luthra, S.K., Osman, S., Hume, S.P., Tilsley, D.W.O., Waters, S.L., Poole, K.G., Price, P., Brady, F. J. Label Compd. Radiopharm., 1993, 32, 521-22.
63. Roberts, A.D., Oakes, T.R., Nickles, R.J. Appl. Radiat. Isot., 1995, 32, 87-91.
64. Nickles, R.J., Daube, M.E., Ruth, T.J. Appl. Radiat. Isot., 1995, 35, 117-122.
65. Saleem, A., Yap, J., Osman, S., Brady, F., Suttle, B., Lucas, S.V., Jones, T., Price, P.M., Aboagye, E.O. Lancet, 2000, 355(9221), 2125-31.
66. Dimitrakopoulou, A., Strauss, L.G., Clorius, J.H., Ostertag, H., Schlag, P., Heim, M., Oberdorfer, F., Helus, F., Haberkorn, U., van Kaick, G. J. Nucl. Med., 1993, 34(7), 1075-81.
67. Hohenberger, P., Strauss, L.G., Lehner, B., Frohmuller, S., Dimitrakopoulou, A., Schlag, P. Eur. J. Cancer, 1993, 12(6), 1682-6.
68. Kissel, J., Brix, G., Bellemann, M.E., Strauss, L.G., Dimitrakopoulou-Strauss, A., Port, R., Haberkorn, U., Lorenz, W.J. Cancer Res., 1997, 57(16), 3415-23.
69. Moehler, M., Dimitrakopoulou-Strauss, A., Gutzler, F., Raeth, U., Strauss, L.G., Stremmel, W. Cancer, 1998, 83(2), 245-53.
70. Dimitrakopoulou-Strauss, A., Strauss, L.G., Schlag, P., Hohenberger, P., Irngartinger, G., Oberdorfer, F., Doll, J., van Kaick, G. J. Nucl. Med., 1998, 39(3), 465-73.
71. Dimitrakopoulou-Strauss, A., Strauss, L.G., Schlag, P., Hohenberger, P., Mohler, M., Oberdorfer, F., van Kaick, G. J. Nucl. Med., 1998, 39(7), 1197-202.
72. Harte, R.J., Matthews, J.C., O'Reilly, S.M., Tilsley, D.W., Osman, S., Brown, G., Luthra, S.J., Brady, F., Jones, T., Price, P.M. J. Clin. Oncol., 1999, 17(5), 1580-8.
73. Harte, R.J., Matthews, J.C., O'Reilly, S.M., Price, P.M. J. Nucl. Med., 1998, 39(8), 1370-6.
74. Brix, G., Bellemann, M.E., Gerlach, L., Haberkorn, U. Radiology, 1998, 209(1), 259-67.
75. Shani, J., Wolf, W. Cancer Res., 1977, 37(7), 2306-8.
76. Presant, C.A., Wolf, W., Albright, M.J., Servis, K.L., Ring, R, 3rd, Atkinson, D., Ong, R.L., Wiseman, C., King, M., Blayney, D. J. Clin. Oncol., 1990, 8(11), 1868-73.
77. Presant, C.A., Wolf, W., Waluch, V., Wiseman, C., Kennedy, P., Blayney, D., Brechner, R.R. Lancet, 1994, 343(8907), 1184-7.
78. Brady, F., Luthra, S. K., Brown, G. D., Osman, S., Aboagye, E., Saleem, A., Price, P. M. Curr. Pharm. Des., 2001, 7(18), 1863-92.
79. Brandes, A. A., Basso, U., Pasetto, L. M., Ermani, M. Curr. Pharm. Des., 2001, 7(16), 1553-80.
80. Willemsen, A. T., van den Hoff, J. Curr. Pharm. Des., 2002, 8(16), 1513-26.