Lumped constant for [18F]fluorodeoxyglucose in skeletal muscles of obese and nonobese humans

American Journal of Physiology - Endocrinology and Metabolism

Volumn 279, Issue 5 42-5, 2000, Pages

  Peltoniemi, Pauliina ^a,b   Lönnroth, Peter ^a   Laine, Hanna ^a   Oikonen, Vesa ^a   Tolvanen, Tuula ^a   Grönroos, Tove ^a   Strindberg, Lena ^a   Knuuti, Juhani ^a   Nuutila, Pirjo ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Glucose phosphorylation; Glucose transport; Insulin resistance; Microdialysis; Positron emission tomography

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT; FLUORINE; GLUCOSE; INSULIN; RADIOPHARMACEUTICAL AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HUMAN; INSULIN RESISTANCE; MALE; MICRODIALYSIS; MUSCLE BLOOD FLOW; OBESITY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; SKELETAL MUSCLE; BLOOD; COMPUTER ASSISTED EMISSION TOMOGRAPHY; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; KINETICS; METABOLISM; PHOSPHORYLATION; VASCULARIZATION;

BLOOD GLUCOSE; FLUORINE RADIOISOTOPES; FLUORODEOXYGLUCOSE F18; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RESISTANCE; KINETICS; MICRODIALYSIS; MUSCLE, SKELETAL; OBESITY; PHOSPHORYLATION; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0033666889     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.279.5.e1122     Document Type: Article

References (56)

1. Bayesian image reconstruction for emission tomography based on median root prior
2. Reduced postprandial skeletal muscle blood flow contributes to glucose intolerance in human obesity
3. Obesity
4. Effect of insulin on in vivo glucose utilization in individual tissues of anesthetized lactating rats
5. Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men
6. Kinetics of transport and phosphorylation of 2-fluoro-2-deoxy-D-glucose in rat brain
7. The permeability of capillaries in various organs as determined by use of the 'indicator diffusion' method
8. Transcapillary transport of D- and L-glucose in isolated skeletal muscle
9. Capillary permeability to small solutes
10. Radiochemistry automation for PET
11. Synergistic interaction between exercise and insulin on peripheral glucose uptake
12. Glucose clamp technique: A method for quantifying insulin secretion and resistance
13. An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects
14. A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat
15. Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether-supported nucleophilic substitution
16. Minimal influence of blood flow on interstitial glucose and lactate-normal and insulin-resistant muscle
17. Induction of insulin resistance by glucosamine reduces blood flow but not interstitial levels of either glucose or insulin
18. Enzymic and cerebral metabolic effects of 2-deoxy-D-glucose
19. Noninvasive determination of local cerebral metabolic rate of glucose in man
20. 2-Deoxy-D-glucose uptake in cultured human muscle cells
21. Glycerol production in subcutaneous adipose tissue in lean and obese humans
22. A new method for the continuous monitoring of blood glucose by measurement of dissolved oxygen
23. The effect of non-insulin-dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle
24. Determination of the lumped constant for [18F]fluorodeoxyglucose in human skeletal muscle
25. Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance
26. Kinetics of in vivo muscle insulin-mediated glucose uptake in human obesity
27. Preserved relative dispersion but blunted stimulation of mean flow, absolute dispersion, and blood volume by insulin in skeletal muscle of patients with essential hypertension
28. Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity
29. A microdialysis method allowing characterization of intercellular water space in humans
30. Validation of the 'internal reference technique' for calibrating microdialysis catheters in situ
31. Rabbit hindlimb glucose uptake assessed with positron-emitting fluorodeoxyglucose
32. Measurement of interstitial muscle glucose and lactate concentrations during an oral glucose tolerance test
33. Key metabolite kinetics in human skeletal muscle during ischaemia and reperfusion: Measurement by microdialysis
34. Different alterations in the insulin-stimulated glucose uptake in the athlete's heart and skeletal muscle
35. Insulin resistance is localized to skeletal but not heart muscle in type 1 diabetes
36. Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo
37. Insulin action on heart and skeletal muscle glucose uptake in essential hypertension
38. 18F]fluoro-deoxy-glucose and positron emission tomography
39. Capillary permeability in skeletal muscle
40. Permeability of continuous capillaries
41. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations
42. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
43. 18F]2-fluoro-2-deoxyglucose for the measure of myocardial glucose metabolism
44. 2O and positron emission tomography
45. Relationship between limb and muscle blood flow in man
46. Quantitative blood flow measurement of skeletal muscle using oxygen-15-water and PET
47. Regional myocardial blood flow, metabolism and function assessed noninvasively with positron emission tomography
48. Skeletal muscle glycogen content in patients with cirrhosis
49. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat
50. Physical performance of the latest generation of commercial positron scanner
51. Evaluation of the microdialysis technique in the dog fat pad
52. Capillary permeability for smaller hyrophilic tracers in exercising skeletal musclein man and in patients with long-term diabetes mellitus
53. Restricted diffusion in skeletal muscle capillaries in man
54. Insulin resistance characterizes glucose uptake in skeletal muscle but not in the heart in NIDDM
55. Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues
56. Radiotracer production. Fluorine-18 compounds