Microdialysis technique as a method to study the percutaneous penetration of methyl nicotinate through excised human skin, reconstructed epidermis, and human skin in vivo

Pharmaceutical Research

Volumn 17, Issue 2, 2000, Pages 141-147

  Boelsma, Esther ^a   Anderson, Chris ^b   Karlsson, Anneli M J ^b   Ponec, Maria ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

LDPI; Methyl nicotinate; Microdialysis; Percutaneous penetration

Indexed keywords

NICOTINIC ACID METHYL ESTER;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; EPIDERMIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LASER DOPPLER FLOWMETRY; MICRODIALYSIS; NORMAL HUMAN; PRIORITY JOURNAL; VASODILATATION;

ADMINISTRATION, CUTANEOUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPIDERMIS; ERYTHEMA; HUMANS; LASER-DOPPLER FLOWMETRY; MICRODIALYSIS; NICOTINIC ACIDS; REGIONAL BLOOD FLOW; SKIN; VASODILATION;

EID: 0034103596     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007505011474     Document Type: Article

References (30)

1. 1. J. L. Fox, C. D. Yu, W. I. Higuchi, and N. F. H. Ho. General physical model for simultaneous diffusion and metabolism in biological membranes. The computational approach for steady-state case. Int. J. Pharm. 2:41-57 (1979).
2. 2. J. Hadgraft. Percutaneous absorption: possibilities and problems. Int. J. Pharm. 16:255-270 (1983).
3. 3. R. L. Bronaugh and H. I. Maibach. In vitro models for human percutaneous adsorption. In H. I. Maibach and N. J. Lowe (eds), Models in Dermatology, Karger, Basel, Switzerland, 1985, pp. 178-188
4. 4. D. Averbeck, S. Averbeck, J. Blais, A. Moysan, G. Huppe, Moliere, P. Prognon, P. Vigny, and L. Dubertret. Suction blister fluid: its use for pharmacodynamic and toxicological studies of drugs and metabolites in vivo in human skin after topical or systemic administration. In H. I. Maibach, N. J. Lowe (eds), Models in Dermatology, Karger, Basel, Switzerland, 1989; pp. 5-11.
5. 5. A. Zesch and H. Schaefer. Penetrationskinetik von radiomarkiertem hydrocortison aus verschiedenartigen Salbengrundlagen in die menschlichen Haut II in vivo. Arch. Dermatol. Forsch. 225:245-256 (1975).
6. 6. C. Anderson, C. Svensson, F. Sjogren, T. Andersson, and K. Wardell. Human in vivo microdialysis technique can be used to measure cytokines in contact reactions. Curr. Probl. Dermatol. 23:121-130 (1995).
7. 7. U. Ungerstedt. Microdialysis - principles and applications for studies in animals and man. J. Int. Med. 230:365-373 (1991).
8. 8. L. Groth. Cutaneous microdialysis. Methodology and validation. Acta. Derm. Venereol. (Stockh) 76:5-61 (1996).
9. 9. C. Anderson, T. Andersson, and M. Molander. Ethanol absorption across human skin measured by in vivo microdialysis technique. Acta. Derm. Venereol. (Stockh) 71:389-393 (1991).
10. 10. L. Groth. Cutaneous microdialysis. A new technique for the assessment of skin penetration, Curr. Probl. Dermatol. 26:90-98 (1998).
11. 11. L. Hegemann, C. Forstinger, B. Partsch, I. Lagler, S. Krotz, and K. Wolff. Microdialysis in cutaneous pharmacology: kinetic analysis of transdermally delivered nicotine. J. Invest. Dermatol. 104:839-843 (1995).
12. 12. Anderson C, Andersson T, and Andersson RGG. In vivo microdialysis estimation of histamine in human skin. Skin. Pharmacol. 5:177-183 (1992)
13. 13. L. J. Petersen, L. K. Poulsen, J. Sondergaard, and P. S. Skov. The use of cutaneous microdialysis to measure substance-P induced histamine release in intact human skin in vivo. Allergy 47:635-637 (1992).
14. 14. R. H. Guy, R. C. Wester, E. Tur, and H. I. Maibach. Noninvasive assessments of the percutaneous absorption of methyl nicotinate in humans. J. Pharm. Sci. 72:1077-1079 (1983).
15. 15. R. H. Guy, E. M. Carlstrom, D. A. W. Bucks, R. S. Hinz, and H. I. Maibach. Percutaneous penetration of nicotinates: in vivo and in vitro measurements. J. Pharm. Sci. 75:968-972 (1986).
16. 16. R. Kohli, W. I. Archer, and A. Li Wan Po. Laser velocimetry for the non-invasive assessment of the percutaneous absorption of nicotinates. Int. J. Pharm. 36:91-98 (1987).
17. 17. M. Ponec, A. Weerheim, J. Kempenaar, A. Mulder, G. S. Gooris, J. Bouwstra, and A. M. Mommaas. The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C. J. Invest. Dermatol. 109:348-355 (1997).
18. 18. A. Jakobsson and G. E. Nilsson. Prediction of sampling depth and photon pathlength in laser Doppler flowmetry. Med. Biol. Eng. Comput. 31:301-307 (1993).
19. 19. K. Wårdell, A. Jakobsson, and G. E. Nilsson. Laser Doppler perfusion imaging by dynamic light scattering. IEEE Trans. Biomed. Eng. 40:309-316 (1993).
20. 20. M. Linden, K. Wårdell, T. Andersson, and C. Anderson. High resolution laser Doppler perfusion imaging for investigation of blood circulation changes after microdialysis probe insertion. Skin Res. Technol. 3:227-232 (1997).
21. 21. L. Lafforgue, I. Eynard, F. Falson, and J. Hadgraft. Physicochemical and physiological parameters of methyl nicotinate percutaneous penetration. Prediction of Percutaneous Penetration, vol 4B;106-108 (1996).
22. 22. J. D. Morrow, J. A. Awad, J. A. Oates, and L. J. Roberts II. Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. J. Invest. Dermatol. 98:812-815 (1992).
23. 23. E. Tur, R. H. Guy, M. Tur, and H. I. Maibach. Noninvasive assessment of local nicotinate pharmacodynamics by photoplethysmography. J. Invest. Dermatol. 80:499-503 (1983).
24. 24. J. P. Fulton, E. M. Farver, and A. P. Moreci. The mechanism of action of rubefacients. J. Invest. Dermatol. 33:317-325 (1959).
25. 25. J. K. Wilkin, G. Fortner, L. A. Reinhardt, O. V. Flowers, S. J. Kilpatrick, and W. C. Streeter. Prostaglandins and nicotinate-provoked increase in cutaneous blood flow. Clin. Pharmacol. Ther. 38:273-277 (1985).
26. 26. J. D. Morrow, W. G. Parsons, and L. J. Roberts. Release of markedly increased quantities of prostaglandin D2 in vivo in humans following the administration of nicotinic acid. Prostaglandins 38:263-274 (1989).
27. 27. A. Zesch, H. Schaefer, and G. Stuttgen. The quantitative distribution of percutaneously applied caffeine in human skin. Arch. Dermatol. Res. 266:277-283 (1979).
28. 28. J. M. Ault, C. M. Riley, N. M. Meltzer, and C. E. Lunte. Dermal microdialysis sampling in vivo. Pharm. Res. 11:1631-1639 (1994).
29. 29. C. J. Gean, H. I. Maibach, and R. H. Guy. Cutaneous response to topical methyl nicotinate in black, oriental, and caucasian subjects Arch. Dermatol. Res. 281:95-98 (1989).
30. 30. E. Tur, H. I. Maibach, and R. H. Guy. Percutaneous penetration of methyl nicotinate at three anatomic sites: evidence for an appendageal contribution to transport? Skin Pharmacol. 4:230-234 (1991).