Versatile macrolide-responsive mammalian expression vectors for multiregulated multigene metabolic engineering

Biotechnology and Bioengineering

Volumn 80, Issue 6, 2002, Pages 691-705

  Weber, Wilfried ^a   Marty, René R ^a   Keller, Bettina ^a   Rimann, Markus ^a   Kramer, Beat P ^a   Fussenegger, Martin ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Dual regulated expression; E.REX; Erythromycin; Gene regulation system; Gene therapy; Macrolide antibiotics; pDuoRex; PIP system; pRetroTriRex; pTRIDENT; pTriRex; pTwin; Streptogramin antibiotics; TET system; Tetracycline antibiotics; Triple regulated expression

Indexed keywords

ANTIBIOTICS; METABOLISM;

GENE REGULATIONS;

GENETIC ENGINEERING;

MACROLIDE; STREPTOGRAMIN; TETRACYCLINE; TRANSACTIVATOR PROTEIN; ANTIINFECTIVE AGENT; STREPTOGRAMIN DERIVATIVE;

ANIMAL CELL; ARTICLE; AUTOREGULATION; EXPRESSION VECTOR; GENE CONTROL; GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; LENTIVIRINAE; METABOLIC ENGINEERING; MOLECULAR CLONING; NONHUMAN; OPERON; PHARMACEUTICS; PLASMID; RETROVIRUS; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TRANSGENE; ANIMAL; CHO CELL; COMPARATIVE STUDY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; HAMSTER; METHODOLOGY; MULTIGENE FAMILY; PHYSIOLOGY; TRANSACTIVATION;

MAMMALIA;

ANIMALS; ANTI-BACTERIAL AGENTS; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC ENGINEERING; GENETIC VECTORS; MACROLIDES; MULTIGENE FAMILY; STREPTOGRAMINS; TETRACYCLINE; TISSUE ENGINEERING; TRANS-ACTIVATION (GENETICS); TRANSGENES;

EID: 0037146818     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10461     Document Type: Article

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