A new topological descriptors based model for predicting intestinal epithelial transport of drugs in caco-2 cell culture

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 7, Issue 2, 2004, Pages 186-199

  Marrero Ponce, Yovani ^a,b,c   Cabrera Pérez, Miguel A ^a,b,c   Romero Zaldivar, Vicente ^a,b,c   González Díaz, Humberto ^a,b,c   Torrens, Francisco ^a,b,c  

^a CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^b UNIVERSIDAD DE CIENFUEGOS CARLOS RAFAEL RODRÍGUEZ   (Cuba)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMINOPHENAZONE; CAFFEINE; CHLORPROMAZINE; CIMETIDINE; CLONIDINE; DESIPRAMINE; DEXAMETHASONE; DIAZEPAM; HYDROCHLOROTHIAZIDE; HYDROCORTISONE; INDOMETACIN; LABETALOL; MELOXICAM; METOPROLOL; NEVIRAPINE; PHENCYCLIDINE; PHENYTOIN; PROGESTERONE; PROPRANOLOL; RANITIDINE; SALAZOSULFAPYRIDINE; SALICYLIC ACID; SCOPOLAMINE; TELMISARTAN; TERBUTALINE; TESTOSTERONE; TIMOLOL; UNINDEXED DRUG; WARFARIN;

ACCURACY; ARTICLE; CELL CULTURE; CELL TRANSPORT; COMPUTER MODEL; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; DRUG ABSORPTION; DRUG PENETRATION; DRUG RESEARCH; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; LINEAR REGRESSION ANALYSIS; MOLECULAR MODEL; PREDICTION; QUANTITATIVE ANALYSIS; VALIDATION PROCESS;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; COMPUTER-AIDED DESIGN; HUMANS; INTESTINAL MUCOSA; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, STATISTICAL; MODELS, THEORETICAL; PERMEABILITY; PHARMACOKINETICS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REGRESSION ANALYSIS; SOFTWARE;

EID: 8844224326     PISSN: 14821826     EISSN: 14821826     Source Type: Journal    
DOI: None     Document Type: Article

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