Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39350-39359

  Palmby, Todd R ^a   Abe, Karon ^a   Der, Channing J ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; LIPIDS; PROTEINS;

TRANSFORMING ACTIVITY;

BIOCHEMISTRY;

AMINO ACID; CYSTEINE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PLECKSTRIN; VAV PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EVALUATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BLOOD PROTEINS; CATALYSIS; CELL CYCLE PROTEINS; CELL LINE; CELL MEMBRANE; CYSTEINE; DNA, COMPLEMENTARY; GENE DELETION; GENES, REPORTER; HUMANS; MICE; MICROSCOPY, CONFOCAL; MUTATION; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-VAV; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; SUBCELLULAR FRACTIONS; TRANSFECTION;

ANIMALIA;

EID: 0037131365     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202641200     Document Type: Article

References (53)

1. Whitehead, I. P., Campbell, S., Rossman, K. L., and Der, C. J. (1997) Biochim. Biophys. Acta 1332, F1-F23
2. Van Aelst, L., and D'Souza-Schorey, C. (1997) Genes Dev. 11, 2295-2322
3. Cerione, R. A., and Zheng, Y. (1996) Curr. Opin. Cell Biol. 8, 216-222
4. Zohn, I. M., Campbell, S. L., Khosravi-Far, R., Rossman, K. L., and Der, C. J. (1998) Oncogene 17, 1415-1438
5. Ridley, A. J. (2001) Trends Cell Biol. 11, 471-477
6. Bishop, A. L., and Hall, A. (2000) Biochem. J. 348, 241-255
7. Bustelo, X. R. (2000) Mol. Cell. Biol. 20, 1461-1477
8. Han, J., Das, B., Wei, W., Van Aelst, L., Mosteller, R. D., Khosravi-Far, R., Westwick, J. K., Der, C. J., and Broek, D. (1997) Mol. Cell. Biol. 17, 1346-1353
9. Crespo, P., Schuebel, K. E., Ostrom, A. A., Gutkind, J. S., and Bustelo, X. R. (1997) Nature 385, 169-172
10. Schuebel, K. E., Movilla, N., Rosa, J. L., and Bustelo, X. R. (1998) EMBO J. 17, 6608-6621
11. Abe, K., Rossman, K. L., Liu, B., Ritola, K. D., Chiang, D., Campbell, S. L., Burridge, K., and Der, C. J. (2000) J. Biol. Chem. 275, 10141-10149
12. Liu, B. P., and Burridge, K. (2000) Mol. Cell. Biol. 20, 7160-7169
13. Movilla, N., and Bustelo, X. R. (1999) Mol. Cell. Biol. 19, 7870-7885
14. Zeng, L., Sachdev, P., Yan, L., Chan, J. L., Trenkle, T., McClelland, M., Welsh, J., and Wang, L. H. (2000) Mol. Cell. Biol. 20, 9212-9224
15. Lemmon, M. A., Falasca, M., Ferguson, K. M., and Schlessinger, J. (1997) Trends Cell Biol. 7, 237-242
16. Whitehead, I. P., Kirk, H., Tognon, C., Trigo-Gonzalez, G., and Kay, R. (1995) J. Biol. Chem. 271, 18388-18395
17. Whitehead, I. P., Lambert, Q. T., Glaven, J. A., Abe, K., Rossman, K. L., Mahon, G. M., Trzaskos, J. M. Kay, R., Campbell, S. L., and Der, C. J. (1999) Mol. Cell. Biol. 19, 7759-7770
18. Zheng, Y., Zangrilli, D., Cerione, R. A., and Eva, A. (1996) J. Biol. Chem. 271, 19017-19020
19. Lemmon, M. A., Ferguson, K. M., and Schlessinger, J. (1996) Cell 85, 621-624
20. Han, J., Luby-Phelps, K., Das, B., Shu, X., Xia, Y., Mosteller, R. D., Krishna, U. M., Falck, J. R., White, M. A., and Broek, D. (1998) Science 279, 558-560
21. Das, B., Shu, X., Day, G. J., Han, J., Krishna, U. M., Falck, J. R., and Broek, D. (2000) J. Biol. Chem. 275, 15074-15081
22. Ma, A. D., Metjian, A., Bagrodia, S., Taylor, S., and Abrams, C. S. (1998) Mol. Cell. Biol. 18, 4744-4751
23. Booden, M. A., Campbell, S. L., and Der, C. J. (2002) Mol. Cell. Biol. 22, 2487-2497
24. Bustelo, X. R. (2001) Oncogene 20, 6372-6381
25. Katzav, S., Cleveland, J. L., Heslop, H. E., and Pulido, D. (1991) Mol. Cell. Biol. 11, 1912-1920
26. Abe, K., Whitehead, I. P., O'Bryan, J. P., and Der, C. J. (1999) J. Biol. Chem. 274, 30410-30418
27. Bustelo, X. R. (1996) Crit. Rev. Oncog. 7, 65-88
28. Groysman, M., Nagano, M., Shaanan, B., and Katzav, S. (1998) Oncogene 17, 1597-1606
29. Katzav, S. (1993) Oncogene 8, 1757-1763
30. Coppola, J., Bryant, S., Koda, T., Conway, D., and Barbacid, M. (1991) Cell Growth Diff. 2, 95-105
31. Hurley, J. H., and Misra, S. (2000) nnu. Rev,(2000)Annu. Rew Biophys. Biomol. Struct. 29, 49-79
32. Sharkey, N. A., Leach, K. L., and Blumberg, P. M. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 607-610
33. Tognon, C. E., Kirk, H. E., Passmore, L. A., Whitehead, I. P., Der, C. J., and Kay, R. J. (1998) Mol. Cell. Biol. 18, 6995-7008
34. Mott, H. R., Carpenter, J. W., Zhong, S., Ghosh, S., Bell, R. M., and Campbell, S. L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8312-8317
35. Clark, G. J., Cox, A. D., Graham, S. M., and Der, C. J. (1995) Methods Enzymol. 255, 395-412
36. Hauser, C. A., Der, C. J., and Cox, A. D. (1994) Methods Enzymol. 238, 271-276
37. Rodriguez-Viciana, P., Warne, P. H., Khwaja, A., Marte, B. M., Pappin, D., Das, P., Waterfield, M. D., Ridley, A., and Downward, J. (1997) Cell 89, 457-467
38. Cox, A. D., Solski, P. A., Jordan, J. D., and Der, C. J. (1995) Methods Enzymol. 255, 195-221
39. Haugh, J. M., Codazzi, F., Teruel, M., and Meyer, T. (2000) J. Cell Biol. 151, 1269-1280
40. Oancea, E., Teruel, M. N., Quest, A. F., and Meyer, T. (1998) J. Cell Biol. 140, 485-498
41. Cohen, G. B., Ren, R., and Baltimore, D. (1995) Cell 80, 237-248
42. Pawson, T. (1995) Nature 373, 573-580
43. Clark, G. J., Drugan, J. K., Rossman, K. L., Carpenter, J. W., Rogers-Graham, K., Fu, H., Der, C. J., and Campbell, S. L. (1997) J. Biol. Chem. 272, 20990-20993
44. Solski, P. A., Quilliam, L. A., Coats, S. G., Der, C. J., and Buss, J. E. (1995) Methods Enzymol. 250, 435-454
45. Watton, S. J., and Downward, J. (1999) Curr. Biol. 9, 433-436
46. Worthylake, D. K., Rossman, K. L., and Sondek, J. (2000) Nature 408, 682-688
47. Rossman, K. L., Worthylake, D. K., Snyder, J. T., Siderovski, D. P., Campbell, S. L., and Sondek, J. (2002) EMBO J. 21, 1315-1326
48. Snyder, J. T., Worthylake, D. K., Rossman, K. L., Betts, L., Pruitt, W. M., Siderovski, D. P., Der, C. J., and Sondek, J. (2002) Nat. Struct. Biol. 9, 468-475
49. Snyder, J. T., Rossman, K. L., Baumeister, M. A., Pruitt, W. M., Siderovski, D. P., Der, C. J., Lemmon, M. A., and Sondek, J. (2001) J. Biol. Chem. 276, 45868-45875
50. Ferguson, K. M., Kavran, J. M., Sankaran, V. G., Fournier, E., Isakoff, S. J., Skolnik, E. Y., and Lemmon, M. A. (2000) Mol. Cell 6, 373-384
51. Lietzke, S. E., Bose, S., Cronin, T., Klarlund, J., Chawla, A., Czech, M. P., and Lambright, D. G. (2000) Mol. Cell 6, 385-394
52. Liu, X., Wang, H., Eberstadt, M., Schnuchel, A., Olejniczak, E. T., Meadows, R. P., Schkeryantz, J. M., Janowick, D. A., Harlan, J. E., Harris, E. A., Staunton, D. E., and Fesik, S. W. (1998) Cell 95, 269-277
53. Rossman, K. L., and Campbell, S. L. (2000) Methods Enzymol. 325, 25-38