-
1
-
-
0032527805
-
Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1
-
Alberts A.S. Treisman R. Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1 EMBO J 17 1998 4075-4085
-
(1998)
EMBO J.
, vol.17
, pp. 4075-4085
-
-
Alberts, A.S.1
Treisman, R.2
-
2
-
-
0033695698
-
The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension
-
[see comments]
-
Awasaki T. Saito M. Sone M. Suzuki E. Sakai R. Ito K. Hama C. The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension [see comments] Neuron 26 2000 119-131
-
(2000)
Neuron
, vol.26
, pp. 119-131
-
-
Awasaki, T.1
Saito, M.2
Sone, M.3
Suzuki, E.4
Sakai, R.5
Ito, K.6
Hama, C.7
-
3
-
-
0033679001
-
The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo
-
[see comments]
-
Bateman J. Shu H. Van Vactor D. The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo [see comments] Neuron 26 2000 93-106
-
(2000)
Neuron
, vol.26
, pp. 93-106
-
-
Bateman, J.1
Shu, H.2
Van Vactor, D.3
-
4
-
-
0034960521
-
The Trio family of guanine-nucleotide-exchange factors: Regulators of axon guidance
-
Bateman J. Van Vactor D. The Trio family of guanine-nucleotide-exchange factors: regulators of axon guidance J Cell Sci 114 2001 1973-1980
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 1973-1980
-
-
Bateman, J.1
Van Vactor, D.2
-
6
-
-
0032518914
-
The two guanine nucleotide exchange factor domains of Trio link the Rac1 and the RhoA pathways in vivo
-
Bellanger J.M. Lazaro J.B. Diriong S. Fernandez A. Lamb N. Debant A. The two guanine nucleotide exchange factor domains of Trio link the Rac1 and the RhoA pathways in vivo Oncogene 16 1998 147-152
-
(1998)
Oncogene
, vol.16
, pp. 147-152
-
-
Bellanger, J.M.1
Lazaro, J.B.2
Diriong, S.3
Fernandez, A.4
Lamb, N.5
Debant, A.6
-
8
-
-
0036210706
-
Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation
-
Booden M.A. Campbell S.L. Der C.J. Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation Mol Cell Biol 22 2002 2487-2497
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 2487-2497
-
-
Booden, M.A.1
Campbell, S.L.2
Der, C.J.3
-
9
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso O.A. Chiariello M. Yu J.C. Teramoto H. Crespo P. Xu N. Miki T. Gutkind J.S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway Cell 81 1995 1137-1146
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
Miki, T.7
Gutkind, J.S.8
-
10
-
-
0034685772
-
Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding
-
Das B. Shu X. Day G.J. Han J. Krishna U.M. Falck J.R. Broek D. Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding J Biol Chem 275 2000 15074-15081
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15074-15081
-
-
Das, B.1
Shu, X.2
Day, G.J.3
Han, J.4
Krishna, U.M.5
Falck, J.R.6
Broek, D.7
-
11
-
-
0029952315
-
The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
-
Debant A. Serra-Pages C. Seipel K. S. O. B., Tang M. Park S.H. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains Proc Natl Acad Sci U S A 93 1996 5466-5471
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 5466-5471
-
-
Debant, A.1
Serra-Pages, C.2
Seipel, K.S.O.B.3
Tang, M.4
Park, S.H.5
-
12
-
-
0037133037
-
The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth
-
Estrach S. Schmidt S. Diriong S. Penna A. Blangy A. Fort P. Debant A. The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth Curr Biol 12 2002 307-312
-
(2002)
Curr. Biol.
, vol.12
, pp. 307-312
-
-
Estrach, S.1
Schmidt, S.2
Diriong, S.3
Penna, A.4
Blangy, A.5
Fort, P.6
Debant, A.7
-
14
-
-
0033593337
-
The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells
-
Glaven J.A. Whitehead I. Bagrodia S. Kay R. Cerione R.A. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells J Biol Chem 274 1999 2279-2285
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2279-2285
-
-
Glaven, J.A.1
Whitehead, I.2
Bagrodia, S.3
Kay, R.4
Cerione, R.A.5
-
15
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A. Rho GTPases and the actin cytoskeleton Science 279 1998 509-514
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
16
-
-
15144353776
-
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
-
Han J. Luby-Phelps K. Das B. Shu X. Xia Y. Mosteller R.D. Krishna U.M. Falck J.R. White M.A. Broek D. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav Science 279 1998 558-560
-
(1998)
Science
, vol.279
, pp. 558-560
-
-
Han, J.1
Luby-Phelps, K.2
Das, B.3
Shu, X.4
Xia, Y.5
Mosteller, R.D.6
Krishna, U.M.7
Falck, J.R.8
White, M.A.9
Broek, D.10
-
17
-
-
0034663568
-
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
-
Lemmon M.A. Ferguson K.M. Signal-dependent membrane targeting by pleckstrin homology (PH) domains Biochem J 350 Pt 1 2000 1-18
-
(2000)
Biochem J
, vol.350
, Issue.PART 1
, pp. 1-18
-
-
Lemmon, M.A.1
Ferguson, K.M.2
-
18
-
-
0037138405
-
Pleckstrin homology domains and the cytoskeleton
-
Lemmon M.A. Ferguson K.M. Abrams C.S. Pleckstrin homology domains and the cytoskeleton FEBS Lett 513 2002 71-76
-
(2002)
FEBS Lett.
, vol.513
, pp. 71-76
-
-
Lemmon, M.A.1
Ferguson, K.M.2
Abrams, C.S.3
-
19
-
-
0029939448
-
PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface
-
Lemmon M.A. Ferguson K.M. Schlessinger J. PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface Cell 85 1996 621-624
-
(1996)
Cell
, vol.85
, pp. 621-624
-
-
Lemmon, M.A.1
Ferguson, K.M.2
Schlessinger, J.3
-
20
-
-
0032538295
-
NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio
-
Liu X. Wang H. Eberstadt M. Schnuchel A. Olejniczak E.T. Meadows R.P. Schkeryantz J.M. Janowick D.A. Harlan J.E. Harris E.A. et al. NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio Cell 95 1998 269-277
-
(1998)
Cell
, vol.95
, pp. 269-277
-
-
Liu, X.1
Wang, H.2
Eberstadt, M.3
Schnuchel, A.4
Olejniczak, E.T.5
Meadows, R.P.6
Schkeryantz, J.M.7
Janowick, D.A.8
Harlan, J.E.9
Harris, E.A.10
-
21
-
-
0034574572
-
Rho GTPases in neuronal morphogenesis
-
Luo L. Rho GTPases in neuronal morphogenesis Nat Rev Neurosci 1 2000 173-180
-
(2000)
Nat. Rev. Neurosci.
, vol.1
, pp. 173-180
-
-
Luo, L.1
-
23
-
-
0030931216
-
Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation
-
Michiels F. Stam J.C. Hordijk P.L. van der Kammen R.A. Ruuls-Van Stalle L. Feltkamp C.A. Collard J.G. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation J Cell Biol 137 1997 387-398
-
(1997)
J. Cell Biol.
, vol.137
, pp. 387-398
-
-
Michiels, F.1
Stam, J.C.2
Hordijk, P.L.3
van der Kammen, R.A.4
Ruuls-Van Stalle, L.5
Feltkamp, C.A.6
Collard, J.G.7
-
24
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden A. Lin A. Claret F.X. Abo A. Karin M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs Cell 81 1995 1147-1157
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.X.3
Abo, A.4
Karin, M.5
-
25
-
-
0032546654
-
Activation of G1 progression, JNK mitogen-activated protein kinase, and actin filament assembly by the exchange factor FGD1
-
Nagata K. Driessens M. Lamarche N. Gorski J.L. Hall A. Activation of G1 progression, JNK mitogen-activated protein kinase, and actin filament assembly by the exchange factor FGD1 J Biol Chem 273 1998 15453-15457
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15453-15457
-
-
Nagata, K.1
Driessens, M.2
Lamarche, N.3
Gorski, J.L.4
Hall, A.5
-
27
-
-
0032559211
-
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos
-
Nimnual A.S. Yatsula B.A. Bar-Sagi D. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos Science 279 1998 560-563
-
(1998)
Science
, vol.279
, pp. 560-563
-
-
Nimnual, A.S.1
Yatsula, B.A.2
Bar-Sagi, D.3
-
30
-
-
0037131365
-
Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity
-
Palmby T.R. Abe K. Der C.J. Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity J Biol Chem 277 2002 39350-39359
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39350-39359
-
-
Palmby, T.R.1
Abe, K.2
Der, C.J.3
-
31
-
-
0033777135
-
Bacterial expressed DH and DH/PH domains
-
Rossman K.L. Campbell S.L. Bacterial expressed DH and DH/PH domains Methods Enzymol 325 2000 25-38
-
(2000)
Methods Enzymol.
, vol.325
, pp. 25-38
-
-
Rossman, K.L.1
Campbell, S.L.2
-
32
-
-
0037086652
-
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange
-
Rossman K.L. Worthylake D.K. Snyder J.T. Siderovski D.P. Campbell S.L. Sondek J. A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange EMBO J 21 2002 1315-1326
-
(2002)
EMBO J
, vol.21
, pp. 1315-1326
-
-
Rossman, K.L.1
Worthylake, D.K.2
Snyder, J.T.3
Siderovski, D.P.4
Campbell, S.L.5
Sondek, J.6
-
33
-
-
0035375109
-
Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain
-
Russo C. Gao Y. Mancini P. Vanni C. Porotto M. Falasca M. Torrisi M.R. Zheng Y. Eva A. Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain J Biol Chem 276 2001 19524-19531
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19524-19531
-
-
Russo, C.1
Gao, Y.2
Mancini, P.3
Vanni, C.4
Porotto, M.5
Falasca, M.6
Torrisi, M.R.7
Zheng, Y.8
Eva, A.9
-
34
-
-
0037125232
-
Identification of the first Rho-GEF inhibitor, TRIPalpha, which targets the RhoA-specific GEF domain of Trio
-
Schmidt S. Diriong S. Méry J. Fabbrizio E. Debant A. Identification of the first Rho-GEF inhibitor, TRIPalpha, which targets the RhoA-specific GEF domain of Trio FEBS Lett 523 2002 35-42
-
(2002)
FEBS Lett.
, vol.523
, pp. 35-42
-
-
Schmidt, S.1
Diriong, S.2
Méry, J.3
Fabbrizio, E.4
Debant, A.5
-
35
-
-
0032538316
-
Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein
-
Soisson S.M. Nimnual A.S. Uy M. Bar-Sagi D. Kuriyan J. Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein Cell 95 1998 259-268
-
(1998)
Cell
, vol.95
, pp. 259-268
-
-
Soisson, S.M.1
Nimnual, A.S.2
Uy, M.3
Bar-Sagi, D.4
Kuriyan, J.5
-
36
-
-
0032617308
-
The DH protein family, exchange factors for Rho-like GTPases
-
Stam J.C. Collard J.G. The DH protein family, exchange factors for Rho-like GTPases Prog Mol Subcell Biol 22 1999 51-83
-
(1999)
Prog. Mol. Subcell. Biol.
, vol.22
, pp. 51-83
-
-
Stam, J.C.1
Collard, J.G.2
-
37
-
-
0032549710
-
UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans
-
Steven R. Kubiseski T.J. Zheng H. Kulkarni S. Mancillas J. Ruiz Morales A. Hogue C.W. Pawson T. Culotti J. UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans Cell 92 1998 785-795
-
(1998)
Cell
, vol.92
, pp. 785-795
-
-
Steven, R.1
Kubiseski, T.J.2
Zheng, H.3
Kulkarni, S.4
Mancillas, J.5
Ruiz Morales, A.6
Hogue, C.W.7
Pawson, T.8
Culotti, J.9
-
38
-
-
0029155976
-
Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C
-
Whitehead I. Kirk H. Tognon C. Trigo-Gonzalez G. Kay R. Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C J Biol Chem 270 1995 18388-18395
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18388-18395
-
-
Whitehead, I.1
Kirk, H.2
Tognon, C.3
Trigo-Gonzalez, G.4
Kay, R.5
-
39
-
-
0034619877
-
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1
-
Worthylake D.K. Rossman K.L. Sondek J. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1 Nature 408 2000 682-688
-
(2000)
Nature
, vol.408
, pp. 682-688
-
-
Worthylake, D.K.1
Rossman, K.L.2
Sondek, J.3
-
40
-
-
0033538524
-
Pleckstrin homology domains interact with filamentous actin
-
Yao L. Janmey P. Frigeri L.G. Han W. Fujita J. Kawakami Y. Apgar J.R. Kawakami T. Pleckstrin homology domains interact with filamentous actin J Biol Chem 274 1999 19752-19761
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19752-19761
-
-
Yao, L.1
Janmey, P.2
Frigeri, L.G.3
Han, W.4
Fujita, J.5
Kawakami, Y.6
Apgar, J.R.7
Kawakami, T.8
-
41
-
-
0029166210
-
Guanine nucleotide exchange catalyzed by dbl oncogene product
-
Zheng Y. Hart M.J. Cerione R.A. Guanine nucleotide exchange catalyzed by dbl oncogene product Methods in Enzymology 256 1995 77-84
-
(1995)
Methods in Enzymology
, vol.256
, pp. 77-84
-
-
Zheng, Y.1
Hart, M.J.2
Cerione, R.A.3
-
42
-
-
0029783037
-
The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting
-
Zheng Y. Zangrilli D. Cerione R.A. Eva A. The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting J Biol Chem 271 1996 19017-19020
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19017-19020
-
-
Zheng, Y.1
Zangrilli, D.2
Cerione, R.A.3
Eva, A.4
-
43
-
-
0032479153
-
Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42
-
Zhou K. Wang Y. Gorski J.L. Nomura N. Collard J. Bokoch G.M. Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42 J Biol Chem 273 1998 16782-16786
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16782-16786
-
-
Zhou, K.1
Wang, Y.2
Gorski, J.L.3
Nomura, N.4
Collard, J.5
Bokoch, G.M.6
|