Effects of varying the expression level of recombinant human mGlu1α receptors on the pharmacological properties of agonists and antagonists

British Journal of Pharmacology

Volumn 126, Issue 4, 1999, Pages 873-882

  Hermans, Emmanuel ^a,b   Challiss, R A John ^a   Nahorski, Stefan R ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Inducible expression; Inositol 1,4,5 trisphosphate; IPTG; LacSwitch; Phosphoinositide turnover; Receptor induction; Type 1 metabotropic glutamate receptor

Indexed keywords

3,5 DIHYDROXYPHENYLGLYCINE; 4 CARBOXY 3 HYDROXYPHENYLGLYCINE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; CYCLOLEUCINE; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL PHOSPHATE; LITHIUM ION; METABOTROPIC RECEPTOR; PHOSPHATIDYLINOSITIDE; PYRANOSIDE; QUISQUALIC ACID; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; FEMALE; HYDROLYSIS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY;

EID: 0032956333     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702359     Document Type: Article

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