-
1
-
-
0000937789
-
Contribution to the knowledge of sarcoma
-
[CrossRef] [PubMed]
-
Coley, W.B. Contribution to the knowledge of sarcoma. Ann. Surg. 1891, 14, 199-220. [CrossRef] [PubMed]
-
(1891)
Ann. Surg
, vol.14
, pp. 199-220
-
-
Coley, W.B.1
-
2
-
-
1642578298
-
Dr william coley and tumour regression: A place in history or in the future
-
[PubMed]
-
Hoption Cann, S.A.; van Netten, J.P.; van Netten, C. Dr william coley and tumour regression: A place in history or in the future. Postgrad. Med. J. 2003, 79, 672-680. [PubMed]
-
(2003)
Postgrad. Med. J
, vol.79
, pp. 672-680
-
-
Hoption Cann, S.A.1
van Netten, J.P.2
van Netten, C.3
-
4
-
-
0002314163
-
Discussion
-
Lawrence, H.S., Ed.; Hoeber-Harper: New York, NY, USA
-
Thomas, L. Discussion. In Cellular and Humoral Aspects of the Hypersensitive States; Lawrence, H.S., Ed.; Hoeber-Harper: New York, NY, USA, 1959; pp. 529-533.
-
(1959)
Cellular and Humoral Aspects of the Hypersensitive States
, pp. 529-533
-
-
Thomas, L.1
-
5
-
-
0015977440
-
Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice
-
[CrossRef] [PubMed]
-
Stutman, O. Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice. Science 1974, 183, 534-536. [CrossRef] [PubMed]
-
(1974)
Science
, vol.183
, pp. 534-536
-
-
Stutman, O.1
-
6
-
-
0018742391
-
Chemical carcinogenesis in nude mice: Comparison between nude mice from homozygous matings and heterozygous matings and effect of age and carcinogen dose
-
[PubMed]
-
Stutman, O. Chemical carcinogenesis in nude mice: Comparison between nude mice from homozygous matings and heterozygous matings and effect of age and carcinogen dose. J. Natl. Cancer Inst. 1979, 62, 353-358. [PubMed]
-
(1979)
J. Natl. Cancer Inst
, vol.62
, pp. 353-358
-
-
Stutman, O.1
-
7
-
-
0035320526
-
A fresh look at tumor immunosurveillance and immunotherapy
-
[CrossRef] [PubMed]
-
Smyth, M.J.; Godfrey, D.I.; Trapani, J.A. A fresh look at tumor immunosurveillance and immunotherapy. Nat. Immunol. 2001, 2, 293-299. [CrossRef] [PubMed]
-
(2001)
Nat. Immunol
, vol.2
, pp. 293-299
-
-
Smyth, M.J.1
Godfrey, D.I.2
Trapani, J.A.3
-
8
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
[CrossRef] [PubMed]
-
Dunn, G.P.; Bruce, A.T.; Ikeda, H.; Old, L.J.; Schreiber, R.D. Cancer immunoediting: From immunosurveillance to tumor escape. Nat. Immunol. 2002, 3, 991-998. [CrossRef] [PubMed]
-
(2002)
Nat. Immunol
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
Old, L.J.4
Schreiber, R.D.5
-
9
-
-
4143141823
-
The immunobiology of cancer immunosurveillance and immunoediting
-
[CrossRef] [PubMed]
-
Dunn, G.P.; Old, L.J.; Schreiber, R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004, 21, 137-148. [CrossRef] [PubMed]
-
(2004)
Immunity
, vol.21
, pp. 137-148
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
10
-
-
2542430341
-
The three Es of cancer immunoediting
-
[CrossRef] [PubMed]
-
Dunn, G.P.; Old, L.J.; Schreiber, R.D. The three Es of cancer immunoediting. Annu. Rev. Immunol. 2004, 22, 329-360. [CrossRef] [PubMed]
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 329-360
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
11
-
-
0035953308
-
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
[CrossRef] [PubMed]
-
Shankaran, V.; Ikeda, H.; Bruce, A.T.; White, J.M.; Swanson, P.E.; Old, L.J.; Schreiber, R.D. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001, 410, 1107-1111. [CrossRef] [PubMed]
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
White, J.M.4
Swanson, P.E.5
Old, L.J.6
Schreiber, R.D.7
-
12
-
-
79953059789
-
Natural innate and adaptive immunity to cancer
-
[CrossRef] [PubMed]
-
Vesely, M.D.; Kershaw, M.H.; Schreiber, R.D.; Smyth, M.J. Natural innate and adaptive immunity to cancer. Annu. Rev. Immunol. 2011, 29, 235-271. [CrossRef] [PubMed]
-
(2011)
Annu. Rev. Immunol
, vol.29
, pp. 235-271
-
-
Vesely, M.D.1
Kershaw, M.H.2
Schreiber, R.D.3
Smyth, M.J.4
-
13
-
-
33750321707
-
Interferons, immunity and cancer immunoediting
-
[CrossRef] [PubMed]
-
Dunn, G.P.; Koebel, C.M.; Schreiber, R.D. Interferons, immunity and cancer immunoediting. Nat. Rev. Immunol. 2006, 6, 836-848. [CrossRef] [PubMed]
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 836-848
-
-
Dunn, G.P.1
Koebel, C.M.2
Schreiber, R.D.3
-
14
-
-
34248193253
-
Immune surveillance of tumors
-
[CrossRef] [PubMed]
-
Swann, J.B.; Smyth, M.J. Immune surveillance of tumors. J. Clin. Investig. 2007, 117, 1137-1146. [CrossRef] [PubMed]
-
(2007)
J. Clin. Investig
, vol.117
, pp. 1137-1146
-
-
Swann, J.B.1
Smyth, M.J.2
-
15
-
-
0028500836
-
Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFNγ receptors
-
[CrossRef]
-
Dighe, A.S.; Richards, E.; Old, L.J.; Schreiber, R.D. Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFNγ receptors. Immunity 1994, 1, 447-456. [CrossRef]
-
(1994)
Immunity
, vol.1
, pp. 447-456
-
-
Dighe, A.S.1
Richards, E.2
Old, L.J.3
Schreiber, R.D.4
-
16
-
-
0032560475
-
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
-
[CrossRef] [PubMed]
-
Kaplan, D.H.; Shankaran, V.; Dighe, A.S.; Stockert, E.; Aguet, M.; Old, L.J.; Schreiber, R.D. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc. Natl. Acad. Sci. USA 1998, 95, 7556-7561. [CrossRef] [PubMed]
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
Stockert, E.4
Aguet, M.5
Old, L.J.6
Schreiber, R.D.7
-
17
-
-
84894107349
-
New insights into cancer immunoediting and its three component phases-Elimination, equilibrium and escape
-
[CrossRef] [PubMed]
-
Mittal, D.; Gubin, M.M.; Schreiber, R.D.; Smyth, M.J. New insights into cancer immunoediting and its three component phases-Elimination, equilibrium and escape. Curr. Opin. Immunol. 2014, 27, 16-25. [CrossRef] [PubMed]
-
(2014)
Curr. Opin. Immunol
, vol.27
, pp. 16-25
-
-
Mittal, D.1
Gubin, M.M.2
Schreiber, R.D.3
Smyth, M.J.4
-
18
-
-
0028201732
-
Tolerance, danger, and the extended family
-
[CrossRef] [PubMed]
-
Matzinger, P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 1994, 12, 991-1045. [CrossRef] [PubMed]
-
(1994)
Annu. Rev. Immunol
, vol.12
, pp. 991-1045
-
-
Matzinger, P.1
-
19
-
-
41549163195
-
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
-
[CrossRef] [PubMed]
-
Guerra, N.; Tan, Y.X.; Joncker, N.T.; Choy, A.; Gallardo, F.; Xiong, N.; Knoblaugh, S.; Cado, D.; Greenberg, N.M.; Raulet, D.H. NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 2008, 28, 571-580. [CrossRef] [PubMed]
-
(2008)
Immunity
, vol.28
, pp. 571-580
-
-
Guerra, N.1
Tan, Y.X.2
Joncker, N.T.3
Choy, A.4
Gallardo, F.5
Xiong, N.6
Knoblaugh, S.7
Cado, D.8
Greenberg, N.M.9
Raulet, D.H.10
-
20
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
[CrossRef] [PubMed]
-
Koebel, C.M.; Vermi, W.; Swann, J.B.; Zerafa, N.; Rodig, S.J.; Old, L.J.; Smyth, M.J.; Schreiber, R.D. Adaptive immunity maintains occult cancer in an equilibrium state. Nature 2007, 450, 903-907. [CrossRef] [PubMed]
-
(2007)
Nature
, vol.450
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
Zerafa, N.4
Rodig, S.J.5
Old, L.J.6
Smyth, M.J.7
Schreiber, R.D.8
-
21
-
-
33646755569
-
Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
-
[PubMed]
-
Smyth, M.J.; Dunn, G.P.; Schreiber, R.D. Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv. Immunol. 2006, 90, 1-50. [PubMed]
-
(2006)
Adv. Immunol
, vol.90
, pp. 1-50
-
-
Smyth, M.J.1
Dunn, G.P.2
Schreiber, R.D.3
-
22
-
-
33748987908
-
Cancer despite immunosurveillance: Immunoselection and immunosubversion
-
[CrossRef] [PubMed]
-
Zitvogel, L.; Tesniere, A.; Kroemer, G. Cancer despite immunosurveillance: Immunoselection and immunosubversion. Nat. Rev. Immunol. 2006, 6, 715-727. [CrossRef] [PubMed]
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 715-727
-
-
Zitvogel, L.1
Tesniere, A.2
Kroemer, G.3
-
23
-
-
0036852191
-
Natural selection of tumor variants in the generation of "tumor escape" phenotypes
-
[CrossRef] [PubMed]
-
Khong, H.T.; Restifo, N.P. Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat. Immunol. 2002, 3, 999-1005. [CrossRef] [PubMed]
-
(2002)
Nat. Immunol
, vol.3
, pp. 999-1005
-
-
Khong, H.T.1
Restifo, N.P.2
-
24
-
-
53549102755
-
The tumor microenvironment and its role in promoting tumor growth
-
[CrossRef]
-
Whiteside, T.L. The tumor microenvironment and its role in promoting tumor growth. Oncogene 2008, 27, 5904-5912. [CrossRef]
-
(2008)
Oncogene
, vol.27
, pp. 5904-5912
-
-
Whiteside, T.L.1
-
25
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
[CrossRef] [PubMed]
-
Gajewski, T.F.; Schreiber, H.; Fu, Y.X. Innate and adaptive immune cells in the tumor microenvironment. Nat. Immunol. 2013, 14, 1014-1022. [CrossRef] [PubMed]
-
(2013)
Nat. Immunol
, vol.14
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.X.3
-
26
-
-
0024814687
-
Model predicting survival in stage I melanoma based on tumor progression
-
[CrossRef] [PubMed]
-
Clark, W.H.; Elder, D.E.; Guerry, D.; Braitman, L.E.; Trock, B.J.; Schultz, D.; Synnestvedt, M.; Halpern, A.C. Model predicting survival in stage I melanoma based on tumor progression. J. Natl. Cancer Inst. 1989, 81, 1893-1904. [CrossRef] [PubMed]
-
(1989)
J. Natl. Cancer Inst
, vol.81
, pp. 1893-1904
-
-
Clark, W.H.1
Elder, D.E.2
Guerry, D.3
Braitman, L.E.4
Trock, B.J.5
Schultz, D.6
Synnestvedt, M.7
Halpern, A.C.8
-
27
-
-
0029925375
-
Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
-
[CrossRef]
-
Clemente, C.G.; Mihm, M.C.; Bufalino, R.; Zurrida, S.; Collini, P.; Cascinelli, N. Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer 1996, 77, 1303-1310. [CrossRef]
-
(1996)
Cancer
, vol.77
, pp. 1303-1310
-
-
Clemente, C.G.1
Mihm, M.C.2
Bufalino, R.3
Zurrida, S.4
Collini, P.5
Cascinelli, N.6
-
28
-
-
10644285782
-
Natural killer cells infiltrating colorectal cancer and MHC class I expression
-
[CrossRef]
-
Sandel, M.H.; Speetjens, F.M.; Menon, A.G.; Albertsson, P.A.; Basse, P.H.; Hokland, M.; Nagelkerke, J.F.; Tollenaar, R.A.E.M.; van de Velde, C.J.H.; Kuppen, P.J.K. Natural killer cells infiltrating colorectal cancer and MHC class I expression. Mol. Immunol. 2005, 42, 541-546. [CrossRef]
-
(2005)
Mol. Immunol
, vol.42
, pp. 541-546
-
-
Sandel, M.H.1
Speetjens, F.M.2
Menon, A.G.3
Albertsson, P.A.4
Basse, P.H.5
Hokland, M.6
Nagelkerke, J.F.7
Tollenaar, R.A.E.M.8
van de Velde, C.J.H.9
Kuppen, P.J.K.10
-
29
-
-
84873468174
-
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
-
[CrossRef] [PubMed]
-
Mitchem, J.B.; Brennan, D.J.; Knolhoff, B.L.; Belt, B.A.; Zhu, Y.; Sanford, D.E.; Belaygorod, L.; Carpenter, D.; Collins, L.; Piwnica-Worms, D.; et al. Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses. Cancer Res. 2013, 73, 1128-1141. [CrossRef] [PubMed]
-
(2013)
Cancer Res
, vol.73
, pp. 1128-1141
-
-
Mitchem, J.B.1
Brennan, D.J.2
Knolhoff, B.L.3
Belt, B.A.4
Zhu, Y.5
Sanford, D.E.6
Belaygorod, L.7
Carpenter, D.8
Collins, L.9
Piwnica-Worms, D.10
-
30
-
-
84858800620
-
The immune contexture in human tumours: Impact on clinical outcome
-
[CrossRef] [PubMed]
-
Fridman, W.H.; Pages, F.; Sautes-Fridman, C.; Galon, J. The immune contexture in human tumours: Impact on clinical outcome. Nat. Rev. Cancer 2012, 12, 298-306. [CrossRef] [PubMed]
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 298-306
-
-
Fridman, W.H.1
Pages, F.2
Sautes-Fridman, C.3
Galon, J.4
-
31
-
-
84928582048
-
Shaping of an effective immune microenvironment to and by cancer cells
-
[CrossRef] [PubMed]
-
Becht, E.; Goc, J.; Germain, C.; Giraldo, N.A.; Dieu-Nosjean, M.C.; Sautes-Fridman, C.; Fridman, W.H. Shaping of an effective immune microenvironment to and by cancer cells. Cancer Immunol. Immunother. 2014, 63, 991-997. [CrossRef] [PubMed]
-
(2014)
Cancer Immunol. Immunother
, vol.63
, pp. 991-997
-
-
Becht, E.1
Goc, J.2
Germain, C.3
Giraldo, N.A.4
Dieu-Nosjean, M.C.5
Sautes-Fridman, C.6
Fridman, W.H.7
-
32
-
-
79952093380
-
Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction
-
[CrossRef] [PubMed]
-
Mlecnik, B.; Tosolini, M.; Kirilovsky, A.; Berger, A.; Bindea, G.; Meatchi, T.; Bruneval, P.; Trajanoski, Z.; Fridman, W.H.; Pages, F.; et al. Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction. J. Clin. Oncol. 2011, 29, 610-618. [CrossRef] [PubMed]
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 610-618
-
-
Mlecnik, B.1
Tosolini, M.2
Kirilovsky, A.3
Berger, A.4
Bindea, G.5
Meatchi, T.6
Bruneval, P.7
Trajanoski, Z.8
Fridman, W.H.9
Pages, F.10
-
33
-
-
79952156460
-
TNM staging in colorectal cancer: T is for T cell and M is for memory
-
[CrossRef] [PubMed]
-
Broussard, E.K.; Disis, M.L. TNM staging in colorectal cancer: T is for T cell and M is for memory. J. Clin. Oncol. 2011, 29, 601-603. [CrossRef] [PubMed]
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 601-603
-
-
Broussard, E.K.1
Disis, M.L.2
-
34
-
-
84877076923
-
From the immune contexture to the immunoscore: The role of prognostic and predictive immune markers in cancer
-
[CrossRef] [PubMed]
-
Angell, H.; Galon, J. From the immune contexture to the immunoscore: The role of prognostic and predictive immune markers in cancer. Curr. Opin. Immunol. 2013, 25, 261-267. [CrossRef] [PubMed]
-
(2013)
Curr. Opin. Immunol
, vol.25
, pp. 261-267
-
-
Angell, H.1
Galon, J.2
-
35
-
-
84966900350
-
Immune checkpoint blockade: A new paradigm in treating advanced cancer
-
[PubMed]
-
Kreamer, K.M. Immune checkpoint blockade: A new paradigm in treating advanced cancer. J. Adv. Pract. Oncol. 2014, 5, 418-431. [PubMed]
-
(2014)
J. Adv. Pract. Oncol
, vol.5
, pp. 418-431
-
-
Kreamer, K.M.1
-
36
-
-
1542351347
-
Current developments of immunotherapy in the clinic
-
[CrossRef] [PubMed]
-
Antonia, S.; Mule, J.J.;Weber, J.S. Current developments of immunotherapy in the clinic. Curr. Opin. Immunol. 2004, 16, 130-136. [CrossRef] [PubMed]
-
(2004)
Curr. Opin. Immunol
, vol.16
, pp. 130-136
-
-
Antonia, S.1
Mule, J.J.2
Weber, J.S.3
-
37
-
-
84883469566
-
Adoptive T-cell therapy for cancer: Boutique therapy or treatment modality? Clin
-
[CrossRef] [PubMed]
-
Yee, C. Adoptive T-cell therapy for cancer: Boutique therapy or treatment modality? Clin. Cancer Res. 2013, 19, 4550-4552. [CrossRef] [PubMed]
-
(2013)
Cancer Res
, vol.19
, pp. 4550-4552
-
-
Yee, C.1
-
38
-
-
70449123840
-
Fifteen years of gene therapy based on chimeric antigen receptors: "Are we nearly there yet?"
-
[CrossRef] [PubMed]
-
Dotti, G.; Savoldo, B.; Brenner, M. Fifteen years of gene therapy based on chimeric antigen receptors: "Are we nearly there yet?". Hum. Gene Ther. 2009, 20, 1229-1239. [CrossRef] [PubMed]
-
(2009)
Hum. Gene Ther
, vol.20
, pp. 1229-1239
-
-
Dotti, G.1
Savoldo, B.2
Brenner, M.3
-
39
-
-
84876050411
-
CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia
-
[CrossRef] [PubMed]
-
Davila, M.L.; Kloss, C.C.; Gunset, G.; Sadelain, M. CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia. PLoS ONE 2013, 8, e61338. [CrossRef] [PubMed]
-
(2013)
PLoS ONE
, vol.8
-
-
Davila, M.L.1
Kloss, C.C.2
Gunset, G.3
Sadelain, M.4
-
40
-
-
0028057250
-
Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
-
[PubMed]
-
Reff, M.E.; Carner, K.; Chambers, K.S.; Chinn, P.C.; Leonard, J.E.; Raab, R.; Newman, R.A.; Hanna, N.; Anderson, D.R. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 1994, 83, 435-445. [PubMed]
-
(1994)
Blood
, vol.83
, pp. 435-445
-
-
Reff, M.E.1
Carner, K.2
Chambers, K.S.3
Chinn, P.C.4
Leonard, J.E.5
Raab, R.6
Newman, R.A.7
Hanna, N.8
Anderson, D.R.9
-
41
-
-
0141792169
-
Antibodies as molecular target-based therapy: Trastuzumab
-
[CrossRef] [PubMed]
-
Tokuda, Y. Antibodies as molecular target-based therapy: Trastuzumab. Int. J. Clin. Oncol. 2003, 8, 224-229. [CrossRef] [PubMed]
-
(2003)
Int. J. Clin. Oncol
, vol.8
, pp. 224-229
-
-
Tokuda, Y.1
-
42
-
-
78651345254
-
Releasing the brake on the immune system: Ipilimumab in melanoma and other tumors
-
[CrossRef] [PubMed]
-
Tarhini, A.; Lo, E.; Minor, D.R. Releasing the brake on the immune system: Ipilimumab in melanoma and other tumors. Cancer Biother. Radiopharm. 2010, 25, 601-613. [CrossRef] [PubMed]
-
(2010)
Cancer Biother. Radiopharm
, vol.25
, pp. 601-613
-
-
Tarhini, A.1
Lo, E.2
Minor, D.R.3
-
43
-
-
17644447104
-
Rituximab: The first monoclonal antibody approved for the treatment of lymphoma
-
[CrossRef] [PubMed]
-
Grillo-Lopez, A.J.; White, C.A.; Dallaire, B.K.; Varns, C.L.; Shen, C.D.;Wei, A.; Leonard, J.E.; McClure, A.; Weaver, R.; Cairelli, S.; et al. Rituximab: The first monoclonal antibody approved for the treatment of lymphoma. Curr. Pharm. Biotechnol. 2000, 1, 1-9. [CrossRef] [PubMed]
-
(2000)
Curr. Pharm. Biotechnol
, vol.1
, pp. 1-9
-
-
Grillo-Lopez, A.J.1
White, C.A.2
Dallaire, B.K.3
Varns, C.L.4
Shen, C.D.5
Wei, A.6
Leonard, J.E.7
McClure, A.8
Weaver, R.9
Cairelli, S.10
-
44
-
-
85117869094
-
-
(accessed on 4 February 2015)
-
The Antibody Society. Available online: https://www.Antibodysociety.Org/news/approved_mabs.Pdf (accessed on 4 February 2015).
-
-
-
The Antibody Society1
-
45
-
-
77951556554
-
Evolution of anti-CD20 monoclonal antibody therapeutics in oncology
-
[CrossRef] [PubMed]
-
Oflazoglu, E.; Audoly, L.P. Evolution of anti-CD20 monoclonal antibody therapeutics in oncology. mAbs 2010, 2, 14-19. [CrossRef] [PubMed]
-
(2010)
mAbs
, vol.2
, pp. 14-19
-
-
Oflazoglu, E.1
Audoly, L.P.2
-
46
-
-
62149129236
-
Therapeutic antibodies: Successes, limitations and hopes for the future
-
[CrossRef] [PubMed]
-
Chames, P.; van Regenmortel, M.; Weiss, E.; Baty, D. Therapeutic antibodies: Successes, limitations and hopes for the future. Br. J. Pharmacol. 2009, 157, 220-233. [CrossRef] [PubMed]
-
(2009)
Br. J. Pharmacol
, vol.157
, pp. 220-233
-
-
Chames, P.1
van Regenmortel, M.2
Weiss, E.3
Baty, D.4
-
47
-
-
84857349967
-
Obinutuzumab for the treatment of lymphoproliferative disorders
-
[CrossRef] [PubMed]
-
Owen, C.; Stewart, D.A. Obinutuzumab for the treatment of lymphoproliferative disorders. Expert Opin. Biol. Ther. 2012, 12, 343-351. [CrossRef] [PubMed]
-
(2012)
Expert Opin. Biol. Ther
, vol.12
, pp. 343-351
-
-
Owen, C.1
Stewart, D.A.2
-
48
-
-
84862251353
-
Symmetry breaking: Bispecific antibodies, the beginnings, and 50 years on
-
[PubMed]
-
Riethmuller, G. Symmetry breaking: Bispecific antibodies, the beginnings, and 50 years on. Cancer Immun. 2012, 12, 12-18. [PubMed]
-
(2012)
Cancer Immun
, vol.12
, pp. 12-18
-
-
Riethmuller, G.1
-
49
-
-
77951523463
-
Bispecific antibodies for cancer therapy: The light at the end of the tunnel?
-
[CrossRef] [PubMed]
-
Chames, P.; Baty, D. Bispecific antibodies for cancer therapy: The light at the end of the tunnel? mAbs 2009, 1, 539-547. [CrossRef] [PubMed]
-
(2009)
mAbs
, vol.1
, pp. 539-547
-
-
Chames, P.1
Baty, D.2
-
50
-
-
84937759650
-
The coming of age of engineered multivalent antibodies
-
[CrossRef] [PubMed]
-
Nunez-Prado, N.; Compte, M.; Harwood, S.; Alvarez-Mendez, A.; Lykkemark, S.; Sanz, L.; Alvarez-Vallina, L. The coming of age of engineered multivalent antibodies. Drug Discov. Today 2015, 20, 588-594. [CrossRef] [PubMed]
-
(2015)
Drug Discov. Today
, vol.20
, pp. 588-594
-
-
Nunez-Prado, N.1
Compte, M.2
Harwood, S.3
Alvarez-Mendez, A.4
Lykkemark, S.5
Sanz, L.6
Alvarez-Vallina, L.7
-
51
-
-
0035251453
-
Bispecific human IgG by design
-
[CrossRef]
-
Carter, P. Bispecific human IgG by design. J. Immunol. Methods 2001, 248, 7-15. [CrossRef]
-
(2001)
J. Immunol. Methods
, vol.248
, pp. 7-15
-
-
Carter, P.1
-
52
-
-
33645054805
-
Bispecific antibodies for dual-modality cancer therapy: Killing two signaling cascades with one stone
-
Marvin, J.S.; Zhu, Z. Bispecific antibodies for dual-modality cancer therapy: Killing two signaling cascades with one stone. Curr. Opin. Drug Discov. Dev. 2006, 9, 184-193.
-
(2006)
Curr. Opin. Drug Discov. Dev
, vol.9
, pp. 184-193
-
-
Marvin, J.S.1
Zhu, Z.2
-
53
-
-
84909639757
-
Tumor-antigen-binding bispecific antibodies for cancer treatment
-
[CrossRef] [PubMed]
-
Weidle, U.H.; Kontermann, R.E.; Brinkmann, U. Tumor-antigen-binding bispecific antibodies for cancer treatment. Semin. Oncol. 2014, 41, 653-660. [CrossRef] [PubMed]
-
(2014)
Semin. Oncol
, vol.41
, pp. 653-660
-
-
Weidle, U.H.1
Kontermann, R.E.2
Brinkmann, U.3
-
54
-
-
0021832361
-
Hybrid antibodies can target sites for attack by T cells
-
[CrossRef] [PubMed]
-
Staerz, U.D.; Kanagawa, O.; Bevan, M.J. Hybrid antibodies can target sites for attack by T cells. Nature 1985, 314, 628-631. [CrossRef] [PubMed]
-
(1985)
Nature
, vol.314
, pp. 628-631
-
-
Staerz, U.D.1
Kanagawa, O.2
Bevan, M.J.3
-
55
-
-
0021751543
-
Production of target-specific effector cells using hetero-cross-linked aggregates containing anti-target cell and anti-Fc gamma receptor antibodies
-
[CrossRef] [PubMed]
-
Karpovsky, B.; Titus, J.A.; Stephany, D.A.; Segal, D.M. Production of target-specific effector cells using hetero-cross-linked aggregates containing anti-target cell and anti-Fc gamma receptor antibodies. J. Exp. Med. 1984, 160, 1686-1701. [CrossRef] [PubMed]
-
(1984)
J. Exp. Med
, vol.160
, pp. 1686-1701
-
-
Karpovsky, B.1
Titus, J.A.2
Stephany, D.A.3
Segal, D.M.4
-
56
-
-
0021997079
-
Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody
-
[CrossRef] [PubMed]
-
Perez, P.; Hoffman, R.W.; Shaw, S.; Bluestone, J.A.; Segal, D.M. Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody. Nature 1985, 316, 354-356. [CrossRef] [PubMed]
-
(1985)
Nature
, vol.316
, pp. 354-356
-
-
Perez, P.1
Hoffman, R.W.2
Shaw, S.3
Bluestone, J.A.4
Segal, D.M.5
-
57
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
[CrossRef] [PubMed]
-
Kohler, G.; Milstein, C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975, 256, 495-497. [CrossRef] [PubMed]
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
58
-
-
84858257263
-
Dual targeting strategies with bispecific antibodies
-
[CrossRef] [PubMed]
-
Kontermann, R.E. Dual targeting strategies with bispecific antibodies. mAbs 2012, 4, 182-197. [CrossRef] [PubMed]
-
(2012)
mAbs
, vol.4
, pp. 182-197
-
-
Kontermann, R.E.1
-
59
-
-
34250809003
-
Cancer imaging and therapy with bispecific antibody pretargeting
-
[CrossRef] [PubMed]
-
Goldenberg, D.M.; Chatal, J.F.; Barbet, J.; Boerman, O.; Sharkey, R.M. Cancer imaging and therapy with bispecific antibody pretargeting. Update Cancer Ther. 2007, 2, 19-31. [CrossRef] [PubMed]
-
(2007)
Update Cancer Ther
, vol.2
, pp. 19-31
-
-
Goldenberg, D.M.1
Chatal, J.F.2
Barbet, J.3
Boerman, O.4
Sharkey, R.M.5
-
60
-
-
0029063312
-
Preferential species-restricted heavy/light chain pairing in rat/mouse quadromas
-
[PubMed]
-
Lindhofer, H.; Mocikat, R.; Steipe, B.; Thierfelder, S. Preferential species-restricted heavy/light chain pairing in rat/mouse quadromas. Implications for a single-step purification of bispecific antibodies. J. Immunol. 1995, 155, 219-225. [PubMed]
-
(1995)
Implications for a single-step purification of bispecific antibodies. J. Immunol
, vol.155
, pp. 219-225
-
-
Lindhofer, H.1
Mocikat, R.2
Steipe, B.3
Thierfelder, S.4
-
61
-
-
0029063312
-
Preferential species-restricted heavy light-chain pairing in rat mouse quadromas-implications for a single-step purification of bispecific antibodies
-
[PubMed]
-
Lindhofer, H.; Mocikat, R.; Steipe, B.; Thierfelder, S. Preferential species-restricted heavy light-chain pairing in rat mouse quadromas-implications for a single-step purification of bispecific antibodies. J. Immunol. 1995, 155, 219-225. [PubMed]
-
(1995)
J. Immunol
, vol.155
, pp. 219-225
-
-
Lindhofer, H.1
Mocikat, R.2
Steipe, B.3
Thierfelder, S.4
-
62
-
-
0033178740
-
Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing
-
[PubMed]
-
Zeidler, R.; Reisbach, G.; Wollenberg, B.; Lang, S.; Chaubal, S.; Schmitt, B.; Lindhofer, H. Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing. J. Immunol. 1999, 163, 1246-1252. [PubMed]
-
(1999)
J. Immunol
, vol.163
, pp. 1246-1252
-
-
Zeidler, R.1
Reisbach, G.2
Wollenberg, B.3
Lang, S.4
Chaubal, S.5
Schmitt, B.6
Lindhofer, H.7
-
63
-
-
0034051390
-
The Fc-region of a new class of intact bispecific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumour cells
-
[PubMed]
-
Zeidler, R.; Mysliwietz, J.; Csanady, M.; Walz, A.; Ziegler, I.; Schmitt, B.; Wollenberg, B.; Lindhofer, H. The Fc-region of a new class of intact bispecific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumour cells. Br. J. Cancer 2000, 83, 261-266. [PubMed]
-
(2000)
Br. J. Cancer
, vol.83
, pp. 261-266
-
-
Zeidler, R.1
Mysliwietz, J.2
Csanady, M.3
Walz, A.4
Ziegler, I.5
Schmitt, B.6
Wollenberg, B.7
Lindhofer, H.8
-
64
-
-
0029148633
-
A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
-
[CrossRef] [PubMed]
-
Mack, M.; Riethmuller, G.; Kufer, P. A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity. Proc. Natl. Acad. Sci. USA 1995, 92, 7021-7025. [CrossRef] [PubMed]
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7021-7025
-
-
Mack, M.1
Riethmuller, G.2
Kufer, P.3
-
65
-
-
84925091940
-
Bispecific T-cell engagers for cancer immunotherapy
-
[CrossRef] [PubMed]
-
Huehls, A.M.; Coupet, T.A.; Sentman, C.L. Bispecific T-cell engagers for cancer immunotherapy. Immunol. Cell Biol. 2015, 93, 290-296. [CrossRef] [PubMed]
-
(2015)
Immunol. Cell Biol
, vol.93
, pp. 290-296
-
-
Huehls, A.M.1
Coupet, T.A.2
Sentman, C.L.3
-
66
-
-
0027197493
-
"Diabodies": Small bivalent and bispecific antibody fragments
-
[CrossRef] [PubMed]
-
Holliger, P.; Prospero, T.;Winter, G. "Diabodies": Small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. USA 1993, 90, 6444-6448. [CrossRef] [PubMed]
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6444-6448
-
-
Holliger, P.1
Prospero, T.2
Winter, G.3
-
67
-
-
77954757304
-
Effector cell recruitment with novel Fv-based dual-affinity re-targeting protein leads to potent tumor cytolysis and in vivo B-cell depletion
-
[CrossRef] [PubMed]
-
Johnson, S.; Burke, S.; Huang, L.; Gorlatov, S.; Li, H.; Wang, W.L.; Zhang, W.J.; Tuaillon, N.; Rainey, J.; Barat, B.; et al. Effector cell recruitment with novel Fv-based dual-affinity re-targeting protein leads to potent tumor cytolysis and in vivo B-cell depletion. J. Mol. Biol. 2010, 399, 436-449. [CrossRef] [PubMed]
-
(2010)
J. Mol. Biol
, vol.399
, pp. 436-449
-
-
Johnson, S.1
Burke, S.2
Huang, L.3
Gorlatov, S.4
Li, H.5
Wang, W.L.6
Zhang, W.J.7
Tuaillon, N.8
Rainey, J.9
Barat, B.10
-
68
-
-
0033569478
-
Bispecific tandem diabody for tumor therapy with improved antigen binding and pharmacokinetics
-
[CrossRef] [PubMed]
-
Kipriyanov, S.M.; Moldenhauer, G.; Schuhmacher, J.; Cochlovius, B.; von der Lieth, C.W.; Matys, E.R.; Little, M. Bispecific tandem diabody for tumor therapy with improved antigen binding and pharmacokinetics. J. Mol. Biol. 1999, 293, 41-56. [CrossRef] [PubMed]
-
(1999)
J. Mol. Biol
, vol.293
, pp. 41-56
-
-
Kipriyanov, S.M.1
Moldenhauer, G.2
Schuhmacher, J.3
Cochlovius, B.4
von der Lieth, C.W.5
Matys, E.R.6
Little, M.7
-
69
-
-
0029946383
-
"Knobs-into-holes" engineering of antibody CH3 domains for heavy chain heterodimerization
-
[CrossRef] [PubMed]
-
Ridgway, J.B.; Presta, L.G.; Carter, P. "Knobs-into-holes" engineering of antibody CH3 domains for heavy chain heterodimerization. Protein Eng. 1996, 9, 617-621. [CrossRef] [PubMed]
-
(1996)
Protein Eng
, vol.9
, pp. 617-621
-
-
Ridgway, J.B.1
Presta, L.G.2
Carter, P.3
-
70
-
-
79960592856
-
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
-
[CrossRef] [PubMed]
-
Schaefer, W.; Regula, J.T.; Bahner, M.; Schanzer, J.; Croasdale, R.; Durr, H.; Gassner, C.; Georges, G.; Kettenberger, H.; Imhof-Jung, S.; et al. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies. Proc. Natl. Acad. Sci. USA 2011, 108, 11187-11192. [CrossRef] [PubMed]
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11187-11192
-
-
Schaefer, W.1
Regula, J.T.2
Bahner, M.3
Schanzer, J.4
Croasdale, R.5
Durr, H.6
Gassner, C.7
Georges, G.8
Kettenberger, H.9
Imhof-Jung, S.10
-
71
-
-
85117876650
-
-
(accessed on 31 May 2015)
-
51st Asco Annual Meeting, Chicago. Available online: http://www.roche.com/irp150601.pdf (accessed on 31 May 2015).
-
51st Asco Annual Meeting, Chicago
-
-
-
72
-
-
21844440052
-
Tuning immune responses: Diversity and adaptation of the immunological synapse
-
[CrossRef] [PubMed]
-
Friedl, P.; den Boer, A.T.; Gunzer, M. Tuning immune responses: Diversity and adaptation of the immunological synapse. Nat. Rev. Immunol. 2005, 5, 532-545. [CrossRef] [PubMed]
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 532-545
-
-
Friedl, P.1
den Boer, A.T.2
Gunzer, M.3
-
73
-
-
84949567330
-
T cell motility as modulator of interactions with dendritic cells
-
[CrossRef] [PubMed]
-
Stein, J.V. T cell motility as modulator of interactions with dendritic cells. Front. Immunol. 2015, 6. [CrossRef] [PubMed]
-
(2015)
Front. Immunol
, pp. 6
-
-
Stein, J.V.1
-
74
-
-
84875463042
-
Molecular mechanisms of T cell co-stimulation and co-inhibition
-
[CrossRef] [PubMed]
-
Chen, L.; Flies, D.B. Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat. Rev. Immunol. 2013, 13, 227-242. [CrossRef] [PubMed]
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
75
-
-
0020197844
-
Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex
-
[CrossRef]
-
Reinherz, E.L.; Meuer, S.; Fitzgerald, K.A.; Hussey, R.E.; Levine, H.; Schlossman, S.F. Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex. Cell 1982, 30, 735-743. [CrossRef]
-
(1982)
Cell
, vol.30
, pp. 735-743
-
-
Reinherz, E.L.1
Meuer, S.2
Fitzgerald, K.A.3
Hussey, R.E.4
Levine, H.5
Schlossman, S.F.6
-
76
-
-
0027403865
-
Induction of long-term specific tolerance to allografts in rats by therapy with an anti-CD3-like monoclonal antibody
-
[CrossRef] [PubMed]
-
Nicolls, M.R.; Aversa, G.G.; Pearce, N.W.; Spinelli, A.; Berger, M.F.; Gurley, K.E.; Hall, B.M. Induction of long-term specific tolerance to allografts in rats by therapy with an anti-CD3-like monoclonal antibody. Transplantation 1993, 55, 459-468. [CrossRef] [PubMed]
-
(1993)
Transplantation
, vol.55
, pp. 459-468
-
-
Nicolls, M.R.1
Aversa, G.G.2
Pearce, N.W.3
Spinelli, A.4
Berger, M.F.5
Gurley, K.E.6
Hall, B.M.7
-
78
-
-
0030856803
-
CD3 × CD19 bispecific antibodies and CD28 costimulation for locoregional treatment of low-malignancy non-Hodgkin's lymphoma
-
[CrossRef] [PubMed]
-
Manzke, O.; Titzer, S.; Tesch, H.; Diehl, V.; Bohlen, H. CD3 × CD19 bispecific antibodies and CD28 costimulation for locoregional treatment of low-malignancy non-Hodgkin's lymphoma. Cancer Immunol. Immunother. 1997, 45, 198-202. [CrossRef] [PubMed]
-
(1997)
Cancer Immunol. Immunother
, vol.45
, pp. 198-202
-
-
Manzke, O.1
Titzer, S.2
Tesch, H.3
Diehl, V.4
Bohlen, H.5
-
79
-
-
28944434529
-
Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on mhc class I-negative tumor cells
-
[CrossRef] [PubMed]
-
Offner, S.; Hofmeister, R.; Romaniuk, A.; Kufer, P.; Baeuerle, P.A. Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on mhc class I-negative tumor cells. Mol. Immunol. 2006, 43, 763-771. [CrossRef] [PubMed]
-
(2006)
Mol. Immunol
, vol.43
, pp. 763-771
-
-
Offner, S.1
Hofmeister, R.2
Romaniuk, A.3
Kufer, P.4
Baeuerle, P.A.5
-
80
-
-
77956344338
-
Development and approval of the trifunctional antibody catumaxomab (anti-EpCAM × anti-CD3) as a targeted cancer immunotherapy
-
[CrossRef] [PubMed]
-
Seimetz, D.; Lindhofer, H.; Bokemeyer, C. Development and approval of the trifunctional antibody catumaxomab (anti-EpCAM × anti-CD3) as a targeted cancer immunotherapy. Cancer Treat. Rev. 2010, 36, 458-467. [CrossRef] [PubMed]
-
(2010)
Cancer Treat. Rev
, vol.36
, pp. 458-467
-
-
Seimetz, D.1
Lindhofer, H.2
Bokemeyer, C.3
-
81
-
-
26444477424
-
Evaluation of a panel of molecular markers for the diagnosis of malignant serous effusions
-
[CrossRef] [PubMed]
-
Passebosc-Faure, K.; Li, G.; Lambert, C.; Cottier, M.; Gentil-Perret, A.; Fournel, P.; Perol, M.; Genin, C. Evaluation of a panel of molecular markers for the diagnosis of malignant serous effusions. Clin. Cancer Res. 2005, 11, 6862-6867. [CrossRef] [PubMed]
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 6862-6867
-
-
Passebosc-Faure, K.1
Li, G.2
Lambert, C.3
Cottier, M.4
Gentil-Perret, A.5
Fournel, P.6
Perol, M.7
Genin, C.8
-
82
-
-
0026777532
-
Immunocytochemical staining of serous effusions with the monoclonal antibody Ber-EP4
-
[CrossRef] [PubMed]
-
De Angelis, M.; Buley, I.D.; Heryet, A.; Gray, W. Immunocytochemical staining of serous effusions with the monoclonal antibody Ber-EP4. Cytopathology 1992, 3, 111-117. [CrossRef] [PubMed]
-
(1992)
Cytopathology
, vol.3
, pp. 111-117
-
-
De Angelis, M.1
Buley, I.D.2
Heryet, A.3
Gray, W.4
-
83
-
-
0027430843
-
Utility of Ber-EP4 in the diagnosis of adenocarcinoma in effusions: An immunocytochemical study of 232 cases
-
[CrossRef] [PubMed]
-
Diaz-Arias, A.A.; Loy, T.S.; Bickel, J.T.; Chapman, R.K. Utility of Ber-EP4 in the diagnosis of adenocarcinoma in effusions: An immunocytochemical study of 232 cases. Diagn. Cytopathol. 1993, 9, 516-521. [CrossRef] [PubMed]
-
(1993)
Diagn. Cytopathol
, vol.9
, pp. 516-521
-
-
Diaz-Arias, A.A.1
Loy, T.S.2
Bickel, J.T.3
Chapman, R.K.4
-
84
-
-
78149235833
-
EpCAM in carcinogenesis: The good, the bad or the ugly
-
[CrossRef] [PubMed]
-
Van der Gun, B.T.F.; Melchers, L.J.; Ruiters, M.H.J.; de Leij, L.F.M.H.; McLaughlin, P.M.J.; Rots, M.G. EpCAM in carcinogenesis: The good, the bad or the ugly. Carcinogenesis 2010, 31, 1913-1921. [CrossRef] [PubMed]
-
(2010)
Carcinogenesis
, vol.31
, pp. 1913-1921
-
-
Van der Gun, B.T.F.1
Melchers, L.J.2
Ruiters, M.H.J.3
de Leij, L.F.M.H.4
McLaughlin, P.M.J.5
Rots, M.G.6
-
85
-
-
77954676136
-
The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
-
[CrossRef] [PubMed]
-
Heiss, M.M.; Murawa, P.; Koralewski, P.; Kutarska, E.; Kolesnik, O.O.; Ivanchenko, V.V.; Dudnichenko, A.S.; Aleknaviciene, B.; Razbadauskas, A.; Gore, M.; et al. The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial. Int. J. Cancer 2010, 127, 2209-2221. [CrossRef] [PubMed]
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2209-2221
-
-
Heiss, M.M.1
Murawa, P.2
Koralewski, P.3
Kutarska, E.4
Kolesnik, O.O.5
Ivanchenko, V.V.6
Dudnichenko, A.S.7
Aleknaviciene, B.8
Razbadauskas, A.9
Gore, M.10
-
86
-
-
84855401998
-
Immunomonitoring results of a phase II/III study of malignant ascites patients treated with the trifunctional antibody catumaxomab (anti-EpCAM × anti-CD3)
-
[CrossRef] [PubMed]
-
Jager, M.; Schoberth, A.; Ruf, P.; Hess, J.; Hennig, M.; Schmalfeldt, B.; Wimberger, P.; Strohlein, M.; Theissen, B.; Heiss, M.M.; et al. Immunomonitoring results of a phase II/III study of malignant ascites patients treated with the trifunctional antibody catumaxomab (anti-EpCAM × anti-CD3). Cancer Res. 2012, 72, 24-32. [CrossRef] [PubMed]
-
(2012)
Cancer Res
, vol.72
, pp. 24-32
-
-
Jager, M.1
Schoberth, A.2
Ruf, P.3
Hess, J.4
Hennig, M.5
Schmalfeldt, B.6
Wimberger, P.7
Strohlein, M.8
Theissen, B.9
Heiss, M.M.10
-
87
-
-
34447132202
-
Effective relief of malignant ascites in patients with advanced ovarian cancer by a trifunctional anti-EpCAM × anti-CD3 antibody: A phase I/II study
-
[CrossRef] [PubMed]
-
Burges, A.; Wimberger, P.; Kumper, C.; Gorbounova, V.; Sommer, H.; Schmalfeldt, B.; Pfisterer, J.; Lichinitser, M.; Makhson, A.; Moiseyenko, V.; et al. Effective relief of malignant ascites in patients with advanced ovarian cancer by a trifunctional anti-EpCAM × anti-CD3 antibody: A phase I/II study. Clin. Cancer Res. 2007, 13, 3899-3905. [CrossRef] [PubMed]
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 3899-3905
-
-
Burges, A.1
Wimberger, P.2
Kumper, C.3
Gorbounova, V.4
Sommer, H.5
Schmalfeldt, B.6
Pfisterer, J.7
Lichinitser, M.8
Makhson, A.9
Moiseyenko, V.10
-
88
-
-
0037056226
-
Intraperitoneal bispecific antibody (HEA125 × OKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma
-
[CrossRef] [PubMed]
-
Marme, A.; Strauss, G.; Bastert, G.; Grischke, E.M.; Moldenhauer, G. Intraperitoneal bispecific antibody (HEA125 × OKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma. Int. J. Cancer 2002, 101, 183-189. [CrossRef] [PubMed]
-
(2002)
Int. J. Cancer
, vol.101
, pp. 183-189
-
-
Marme, A.1
Strauss, G.2
Bastert, G.3
Grischke, E.M.4
Moldenhauer, G.5
-
89
-
-
0141456526
-
Characterization of human IgG antimouse antibody in patients with B-cell malignancies
-
De Nardo, G.L.; Mirick, G.R.; Kroger, L.A.; Bradt, B.M.; Lamborn, K.R.; de Nardo, S.J. Characterization of human IgG antimouse antibody in patients with B-cell malignancies. Clin. Cancer Res. 2003, 9, 4013S-4021S.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 4013S-4021S
-
-
De Nardo, G.L.1
Mirick, G.R.2
Kroger, L.A.3
Bradt, B.M.4
Lamborn, K.R.5
de Nardo, S.J.6
-
90
-
-
0032932150
-
Level of anti-mouse-antibody response induced by bi-specific monoclonal antibody OC/TR in ovarian-carcinoma patients is associated with longer survival
-
[CrossRef]
-
Miotti, S.; Negri, D.R.; Valota, O.; Calabrese, M.; Bolhuis, R.L.; Gratama, J.W.; Colnaghi, M.I.; Canevari, S. Level of anti-mouse-antibody response induced by bi-specific monoclonal antibody OC/TR in ovarian-carcinoma patients is associated with longer survival. Int. J. Cancer 1999, 84, 62-68. [CrossRef]
-
(1999)
Int. J. Cancer
, vol.84
, pp. 62-68
-
-
Miotti, S.1
Negri, D.R.2
Valota, O.3
Calabrese, M.4
Bolhuis, R.L.5
Gratama, J.W.6
Colnaghi, M.I.7
Canevari, S.8
-
91
-
-
77951596808
-
Catumaxomab: Clinical development and future directions
-
[CrossRef] [PubMed]
-
Linke, R.; Klein, A.; Seimetz, D. Catumaxomab: Clinical development and future directions. mAbs 2010, 2, 129-136. [CrossRef] [PubMed]
-
(2010)
mAbs
, vol.2
, pp. 129-136
-
-
Linke, R.1
Klein, A.2
Seimetz, D.3
-
92
-
-
58149394138
-
Outcome of adults with acute lymphocytic leukemia after second salvage therapy
-
[CrossRef] [PubMed]
-
O'Brien, S.; Thomas, D.; Ravandi, F.; Faderl, S.; Cortes, J.; Borthakur, G.; Pierce, S.; Garcia-Manero, G.; Kantarjian, H.M. Outcome of adults with acute lymphocytic leukemia after second salvage therapy. Cancer 2008, 113, 3186-3191. [CrossRef] [PubMed]
-
(2008)
Cancer
, vol.113
, pp. 3186-3191
-
-
O'Brien, S.1
Thomas, D.2
Ravandi, F.3
Faderl, S.4
Cortes, J.5
Borthakur, G.6
Pierce, S.7
Garcia-Manero, G.8
Kantarjian, H.M.9
-
93
-
-
78650083131
-
Defining the course and prognosis of adults with acute lymphocytic leukemia in first salvage after induction failure or short first remission duration
-
[CrossRef] [PubMed]
-
Kantarjian, H.M.; Thomas, D.; Ravandi, F.; Faderl, S.; Jabbour, E.; Garcia-Manero, G.; Pierce, S.; Shan, J.; Cortes, J.; O'Brien, S. Defining the course and prognosis of adults with acute lymphocytic leukemia in first salvage after induction failure or short first remission duration. Cancer 2010, 116, 5568-5574. [CrossRef] [PubMed]
-
(2010)
Cancer
, vol.116
, pp. 5568-5574
-
-
Kantarjian, H.M.1
Thomas, D.2
Ravandi, F.3
Faderl, S.4
Jabbour, E.5
Garcia-Manero, G.6
Pierce, S.7
Shan, J.8
Cortes, J.9
O'Brien, S.10
-
94
-
-
0343415665
-
A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes
-
[PubMed]
-
Loffler, A.; Kufer, P.; Lutterbuse, R.; Zettl, F.; Daniel, P.T.; Schwenkenbecher, J.M.; Riethmuller, G.; Dorken, B.; Bargou, R.C. A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes. Blood 2000, 95, 2098-2103. [PubMed]
-
(2000)
Blood
, vol.95
, pp. 2098-2103
-
-
Loffler, A.1
Kufer, P.2
Lutterbuse, R.3
Zettl, F.4
Daniel, P.T.5
Schwenkenbecher, J.M.6
Riethmuller, G.7
Dorken, B.8
Bargou, R.C.9
-
95
-
-
0037143806
-
Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody
-
[CrossRef] [PubMed]
-
Dreier, T.; Lorenczewski, G.; Brandl, C.; Hoffmann, P.; Syring, U.; Hanakam, F.; Kufer, P.; Riethmuller, G.; Bargou, R.; Baeuerle, P.A. Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody. Int. J. Cancer 2002, 100, 690-697. [CrossRef] [PubMed]
-
(2002)
Int. J. Cancer
, vol.100
, pp. 690-697
-
-
Dreier, T.1
Lorenczewski, G.2
Brandl, C.3
Hoffmann, P.4
Syring, U.5
Hanakam, F.6
Kufer, P.7
Riethmuller, G.8
Bargou, R.9
Baeuerle, P.A.10
-
96
-
-
77953228970
-
Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen
-
[CrossRef] [PubMed]
-
Bluemel, C.; Hausmann, S.; Fluhr, P.; Sriskandarajah, M.; Stallcup, W.B.; Baeuerle, P.A.; Kufer, P. Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen. Cancer Immunol. Immunother. 2010, 59, 1197-1209. [CrossRef] [PubMed]
-
(2010)
Cancer Immunol. Immunother
, vol.59
, pp. 1197-1209
-
-
Bluemel, C.1
Hausmann, S.2
Fluhr, P.3
Sriskandarajah, M.4
Stallcup, W.B.5
Baeuerle, P.A.6
Kufer, P.7
-
97
-
-
49649120397
-
Tumor regression in cancer patients by very low doses of a T cell-engaging antibody
-
[CrossRef] [PubMed]
-
Bargou, R.; Leo, E.; Zugmaier, G.; Klinger, M.; Goebeler, M.; Knop, S.; Noppeney, R.; Viardot, A.; Hess, G.; Schuler, M.; et al. Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science 2008, 321, 974-977. [CrossRef] [PubMed]
-
(2008)
Science
, vol.321
, pp. 974-977
-
-
Bargou, R.1
Leo, E.2
Zugmaier, G.3
Klinger, M.4
Goebeler, M.5
Knop, S.6
Noppeney, R.7
Viardot, A.8
Hess, G.9
Schuler, M.10
-
98
-
-
84916639631
-
Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia
-
[CrossRef] [PubMed]
-
Topp, M.S.; Gokbuget, N.; Zugmaier, G.; Klappers, P.; Stelljes, M.; Neumann, S.; Viardot, A.; Marks, R.; Diedrich, H.; Faul, C.; et al. Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia. J. Clin. Oncol. 2014, 32, 4134-4140. [CrossRef] [PubMed]
-
(2014)
J. Clin. Oncol
, vol.32
, pp. 4134-4140
-
-
Topp, M.S.1
Gokbuget, N.2
Zugmaier, G.3
Klappers, P.4
Stelljes, M.5
Neumann, S.6
Viardot, A.7
Marks, R.8
Diedrich, H.9
Faul, C.10
-
99
-
-
84922466555
-
Unleashing the clinical power of T cells: CD19/CD3 Bi-specific T cell engager (BiTEr) antibody construct blinatumomab as a potential therapy
-
[CrossRef] [PubMed]
-
Zimmerman, Z.; Maniar, T.; Nagorsen, D. Unleashing the clinical power of T cells: CD19/CD3 Bi-specific T cell engager (BiTEr) antibody construct blinatumomab as a potential therapy. Int. Immunol. 2015, 27, 31-37. [CrossRef] [PubMed]
-
(2015)
Int. Immunol
, vol.27
, pp. 31-37
-
-
Zimmerman, Z.1
Maniar, T.2
Nagorsen, D.3
-
100
-
-
84878931351
-
Targeting T cells to tumor cells using bispecific antibodies
-
[CrossRef] [PubMed]
-
Frankel, S.R.; Baeuerle, P.A. Targeting T cells to tumor cells using bispecific antibodies. Curr. Opin. Chem. Biol. 2013, 17, 385-392. [CrossRef] [PubMed]
-
(2013)
Curr. Opin. Chem. Biol
, vol.17
, pp. 385-392
-
-
Frankel, S.R.1
Baeuerle, P.A.2
-
101
-
-
84938506999
-
A tetravalent bispecific TandAB (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19+ tumor cells
-
[CrossRef] [PubMed]
-
Reusch, U.; Duell, J.; Ellwanger, K.; Herbrecht, C.; Knackmuss, S.H.; Fucek, I.; Eser, M.; McAleese, F.; Molkenthin, V.; Gall, F.L.; et al. A tetravalent bispecific TandAB (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19+ tumor cells. mAbs 2015, 7, 584-604. [CrossRef] [PubMed]
-
(2015)
mAbs
, vol.7
, pp. 584-604
-
-
Reusch, U.1
Duell, J.2
Ellwanger, K.3
Herbrecht, C.4
Knackmuss, S.H.5
Fucek, I.6
Eser, M.7
McAleese, F.8
Molkenthin, V.9
Gall, F.L.10
-
102
-
-
28744445538
-
MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors
-
[CrossRef] [PubMed]
-
Brischwein, K.; Schlereth, B.; Guller, B.; Steiger, C.; Wolf, A.; Lutterbuese, R.; Offner, S.; Locher, M.; Urbig, T.; Raum, T.; et al. MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. Mol. Immunol. 2006, 43, 1129-1143. [CrossRef] [PubMed]
-
(2006)
Mol. Immunol
, vol.43
, pp. 1129-1143
-
-
Brischwein, K.1
Schlereth, B.2
Guller, B.3
Steiger, C.4
Wolf, A.5
Lutterbuese, R.6
Offner, S.7
Locher, M.8
Urbig, T.9
Raum, T.10
-
103
-
-
33645007038
-
T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct
-
[CrossRef] [PubMed]
-
Schlereth, B.; Quadt, C.; Dreier, T.; Kufer, P.; Lorenczewski, G.; Prang, N.; Brandl, C.; Lippold, S.; Cobb, K.; Brasky, K.; et al. T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct. Cancer Immunol. Immunother. 2006, 55, 503-514. [CrossRef] [PubMed]
-
(2006)
Cancer Immunol. Immunother
, vol.55
, pp. 503-514
-
-
Schlereth, B.1
Quadt, C.2
Dreier, T.3
Kufer, P.4
Lorenczewski, G.5
Prang, N.6
Brandl, C.7
Lippold, S.8
Cobb, K.9
Brasky, K.10
-
104
-
-
85117872702
-
-
(accessed on 18 December 2015)
-
Macrogenics. Available online: http://www.Macrogenics.Com/products-mgd011.html (accessed on 18 December 2015).
-
-
-
Macrogenics1
-
105
-
-
79955970356
-
Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma
-
[CrossRef] [PubMed]
-
Moore, P.A.; Zhang, W.J.; Rainey, G.J.; Burke, S.; Li, H.; Huang, L.; Gorlatov, S.; Veri, M.C.; Aggarwal, S.; Yang, Y.H.; et al. Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma. Blood 2011, 117, 4542-4551. [CrossRef] [PubMed]
-
(2011)
Blood
, vol.117
, pp. 4542-4551
-
-
Moore, P.A.1
Zhang, W.J.2
Rainey, G.J.3
Burke, S.4
Li, H.5
Huang, L.6
Gorlatov, S.7
Veri, M.C.8
Aggarwal, S.9
Yang, Y.H.10
-
106
-
-
85117872989
-
-
(accessed on 18 December 2015)
-
Affimed. Available online: http://www.Affimed.Com/products.php (accessed on 18 December 2015).
-
-
-
Affimed1
-
107
-
-
84944072257
-
Activated T cells armed with bispecific antibodies kill tumor targets
-
[CrossRef] [PubMed]
-
Bhutani, D.; Lum, L.G. Activated T cells armed with bispecific antibodies kill tumor targets. Curr. Opin. Hematol. 2015, 22, 476-483. [CrossRef] [PubMed]
-
(2015)
Curr. Opin. Hematol
, vol.22
, pp. 476-483
-
-
Bhutani, D.1
Lum, L.G.2
-
108
-
-
84944031058
-
A novel bispecific antibody, S-FAB, induces potent cancer cell killing
-
[CrossRef] [PubMed]
-
Li, L.; He, P.; Zhou, C.; Jing, L.; Dong, B.; Chen, S.; Zhang, N.; Liu, Y.; Miao, J.; Wang, Z.; et al. A novel bispecific antibody, S-FAB, induces potent cancer cell killing. J. Immunother. 2015, 38, 350-356. [CrossRef] [PubMed]
-
(2015)
J. Immunother
, vol.38
, pp. 350-356
-
-
Li, L.1
He, P.2
Zhou, C.3
Jing, L.4
Dong, B.5
Chen, S.6
Zhang, N.7
Liu, Y.8
Miao, J.9
Wang, Z.10
-
109
-
-
85047686965
-
A new class of bispecific antibodies to redirect t cells for cancer immunotherapy
-
[CrossRef] [PubMed]
-
Rossi, D.L.; Rossi, E.A.; Cardillo, T.M.; Goldenberg, D.M.; Chang, C.H. A new class of bispecific antibodies to redirect t cells for cancer immunotherapy. mAbs 2014, 6, 381-391. [CrossRef] [PubMed]
-
(2014)
mAbs
, vol.6
, pp. 381-391
-
-
Rossi, D.L.1
Rossi, E.A.2
Cardillo, T.M.3
Goldenberg, D.M.4
Chang, C.H.5
-
110
-
-
84949681670
-
A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys
-
[CrossRef] [PubMed]
-
Smith, E.J.; Olson, K.; Haber, L.J.; Varghese, B.; Duramad, P.; Tustian, A.D.; Oyejide, A.; Kirshner, J.R.; Canova, L.; Menon, J.; et al. A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys. Sci. Rep. 2015, 5, 1-12. [CrossRef] [PubMed]
-
(2015)
Sci. Rep
, vol.5
, pp. 1-12
-
-
Smith, E.J.1
Olson, K.2
Haber, L.J.3
Varghese, B.4
Duramad, P.5
Tustian, A.D.6
Oyejide, A.7
Kirshner, J.R.8
Canova, L.9
Menon, J.10
-
111
-
-
84929648838
-
Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies
-
[CrossRef] [PubMed]
-
Sun, L.L.; Ellerman, D.; Mathieu, M.; Hristopoulos, M.; Chen, X.; Li, Y.; Yan, X.; Clark, R.; Reyes, A.; Stefanich, E.; et al. Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies. Sci. Transl. Med. 2015, 7. [CrossRef] [PubMed]
-
(2015)
Sci. Transl. Med
, pp. 7
-
-
Sun, L.L.1
Ellerman, D.2
Mathieu, M.3
Hristopoulos, M.4
Chen, X.5
Li, Y.6
Yan, X.7
Clark, R.8
Reyes, A.9
Stefanich, E.10
-
112
-
-
0034091286
-
γβ cells: A right time and a right place for a conserved third way of protection
-
[CrossRef] [PubMed]
-
Hayday, A.C. γβ cells: A right time and a right place for a conserved third way of protection. Ann. Rev. Immunol. 2000, 18, 975-1026. [CrossRef] [PubMed]
-
(2000)
Ann. Rev. Immunol
, vol.18
, pp. 975-1026
-
-
Hayday, A.C.1
-
113
-
-
79952208471
-
γδ T cells cross-link innate and adaptive immunity in Mycobacterium tuberculosis infection
-
[CrossRef] [PubMed]
-
Meraviglia, S.; el Daker, S.; Dieli, F.; Martini, F.; Martino, A. γδ T cells cross-link innate and adaptive immunity in Mycobacterium tuberculosis infection. Clin. Dev. Immunol. 2011, 2011. [CrossRef] [PubMed]
-
(2011)
Clin. Dev. Immunol
, pp. 2011
-
-
Meraviglia, S.1
el Daker, S.2
Dieli, F.3
Martini, F.4
Martino, A.5
-
114
-
-
84925287282
-
Gammadelta t cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice
-
[CrossRef] [PubMed]
-
Mehta, P.; Nuotio-Antar, A.M.; Smith, C.W. Gammadelta t cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice. J. Leuk. Biol. 2015, 97, 121-134. [CrossRef] [PubMed]
-
(2015)
J. Leuk. Biol
, vol.97
, pp. 121-134
-
-
Mehta, P.1
Nuotio-Antar, A.M.2
Smith, C.W.3
-
115
-
-
84872930787
-
Six-of-the-best: Unique contributions of gamma delta T cells to immunology
-
[CrossRef] [PubMed]
-
Vantourout, P.; Hayday, A. Six-of-the-best: Unique contributions of gamma delta T cells to immunology. Nat. Rev. Immunol. 2013, 13, 88-100. [CrossRef] [PubMed]
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 88-100
-
-
Vantourout, P.1
Hayday, A.2
-
116
-
-
0029073751
-
Natural and synthetic non-peptide antigens recognized by human gamma delta T cells
-
[CrossRef] [PubMed]
-
Tanaka, Y.; Morita, C.T.; Tanaka, Y.; Nieves, E.; Brenner, M.B.; Bloom, B.R. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature 1995, 375, 155-158. [CrossRef] [PubMed]
-
(1995)
Nature
, vol.375
, pp. 155-158
-
-
Tanaka, Y.1
Morita, C.T.2
Tanaka, Y.3
Nieves, E.4
Brenner, M.B.5
Bloom, B.R.6
-
117
-
-
84892375230
-
Gammadelta T cells and their potential for immunotherapy
-
[CrossRef] [PubMed]
-
Wu, Y.L.; Ding, Y.P.; Tanaka, Y.; Shen, L.W.;Wei, C.H.; Minato, N.; Zhang, W. Gammadelta T cells and their potential for immunotherapy. Int. J. Biol. Sci. 2014, 10, 119-135. [CrossRef] [PubMed]
-
(2014)
Int. J. Biol. Sci
, vol.10
, pp. 119-135
-
-
Wu, Y.L.1
Ding, Y.P.2
Tanaka, Y.3
Shen, L.W.4
Wei, C.H.5
Minato, N.6
Zhang, W.7
-
118
-
-
79952343500
-
γδ T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody
-
[CrossRef] [PubMed]
-
Braza, M.S.; Klein, B.; Fiol, G.; Rossi, J.F. γδ T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody. Haematol. Hematol. J. 2011, 96, 400-407. [CrossRef] [PubMed]
-
(2011)
Haematol. Hematol. J
, vol.96
, pp. 400-407
-
-
Braza, M.S.1
Klein, B.2
Fiol, G.3
Rossi, J.F.4
-
119
-
-
66549084068
-
Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies
-
[CrossRef] [PubMed]
-
Gertner-Dardenne, J.; Bonnafous, C.; Bezombes, C.; Capietto, A.H.; Scaglione, V.; Ingoure, S.; Cendron, D.; Gross, E.; Lepage, J.F.; Quillet-Mary, A.; et al. Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies. Blood 2009, 113, 4875-4884. [CrossRef] [PubMed]
-
(2009)
Blood
, vol.113
, pp. 4875-4884
-
-
Gertner-Dardenne, J.1
Bonnafous, C.2
Bezombes, C.3
Capietto, A.H.4
Scaglione, V.5
Ingoure, S.6
Cendron, D.7
Gross, E.8
Lepage, J.F.9
Quillet-Mary, A.10
-
120
-
-
42549138403
-
Vγ9Vδ2 T cell cytotoxicity against tumor cells is enhanced by monoclonal antibody drugs-Rituximab and trastuzumab
-
[CrossRef] [PubMed]
-
Tokuyama, H.; Hagi, T.; Mattarollo, S.R.; Morley, J.; Wang, Q.; Fai-So, H.; Moriyasu, F.; Nieda, M.; Nicol, A.J. Vγ9Vδ2 T cell cytotoxicity against tumor cells is enhanced by monoclonal antibody drugs-Rituximab and trastuzumab. Int. J. Cancer 2008, 122, 2526-2534. [CrossRef] [PubMed]
-
(2008)
Int. J. Cancer
, vol.122
, pp. 2526-2534
-
-
Tokuyama, H.1
Hagi, T.2
Mattarollo, S.R.3
Morley, J.4
Wang, Q.5
Fai-So, H.6
Moriyasu, F.7
Nieda, M.8
Nicol, A.J.9
-
121
-
-
84930570731
-
Gammadelta T cell activation by bispecific antibodies
-
[CrossRef] [PubMed]
-
Oberg, H.H.; Kellner, C.; Gonnermann, D.; Peipp, M.; Peters, C.; Sebens, S.; Kabelitz, D.; Wesch, D. Gammadelta T cell activation by bispecific antibodies. Cell Immunol. 2015, 296, 41-49. [CrossRef] [PubMed]
-
(2015)
Cell Immunol
, vol.296
, pp. 41-49
-
-
Oberg, H.H.1
Kellner, C.2
Gonnermann, D.3
Peipp, M.4
Peters, C.5
Sebens, S.6
Kabelitz, D.7
Wesch, D.8
-
122
-
-
84896524478
-
Novel bispecific antibodies increase gammadelta T-cell cytotoxicity against pancreatic cancer cells
-
[CrossRef] [PubMed]
-
Oberg, H.H.; Peipp, M.; Kellner, C.; Sebens, S.; Krause, S.; Petrick, D.; Adam-Klages, S.; Rocken, C.; Becker, T.; Vogel, I.; et al. Novel bispecific antibodies increase gammadelta T-cell cytotoxicity against pancreatic cancer cells. Cancer Res. 2014, 74, 1349-1360. [CrossRef] [PubMed]
-
(2014)
Cancer Res
, vol.74
, pp. 1349-1360
-
-
Oberg, H.H.1
Peipp, M.2
Kellner, C.3
Sebens, S.4
Krause, S.5
Petrick, D.6
Adam-Klages, S.7
Rocken, C.8
Becker, T.9
Vogel, I.10
-
123
-
-
84893965118
-
Immune modulation in cancer with antibodies
-
[CrossRef] [PubMed]
-
Page, D.B.; Postow, M.A.; Callahan, M.K.; Allison, J.P.; Wolchok, J.D. Immune modulation in cancer with antibodies. Ann. Rev. Med. 2014, 65, 185-202. [CrossRef] [PubMed]
-
(2014)
Ann. Rev. Med
, vol.65
, pp. 185-202
-
-
Page, D.B.1
Postow, M.A.2
Callahan, M.K.3
Allison, J.P.4
Wolchok, J.D.5
-
124
-
-
85117873654
-
-
(accessed on 18 December 2015)
-
Anaptysbio. Available online: http://www.Anaptysbio.Com/platform/shm-xel-platform/ (accessed on 18 December 2015).
-
-
-
Anaptysbio1
-
125
-
-
85042574383
-
-
(accessed on 18 December 2015)
-
Sorrento Therapeutics. Available online: http://sorrentotherapeutics.com/wp-content/uploads/2014/12/ SABC-2014-Poster-FINAL____Zhang-et-al.pdf (accessed on 18 December 2015).
-
Sorrento Therapeutics
-
-
-
126
-
-
85042574383
-
-
(accessed on 18 December 2015)
-
Sorrento Therapeutics. Available online: http://www.prnewswire.com/news-releases/sorrento-therapeuticsannounces-poster-presentations-on-its-anti-c-metpd-l1-bispecific-antibodies-and-anti-c-met-antibody-drugconjugate-at-the-37th-annual-san-antonio-breast-cancer-symposium-300005983.html (accessed on 18 December 2015).
-
Sorrento Therapeutics
-
-
-
127
-
-
84877602763
-
NK cell-based immunotherapy for malignant diseases
-
[CrossRef] [PubMed]
-
Cheng, M.; Chen, Y.; Xiao, W.; Sun, R.; Tian, Z. NK cell-based immunotherapy for malignant diseases. Cell Mol. Immunol. 2013, 10, 230-252. [CrossRef] [PubMed]
-
(2013)
Cell Mol. Immunol
, vol.10
, pp. 230-252
-
-
Cheng, M.1
Chen, Y.2
Xiao, W.3
Sun, R.4
Tian, Z.5
-
128
-
-
0034715948
-
Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: An 11-year follow-up study of a general population
-
[CrossRef]
-
Imai, K.; Matsuyama, S.; Miyake, S.; Suga, K.; Nakachi, K. Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: An 11-year follow-up study of a general population. Lancet 2000, 356, 1795-1799. [CrossRef]
-
(2000)
Lancet
, vol.356
, pp. 1795-1799
-
-
Imai, K.1
Matsuyama, S.2
Miyake, S.3
Suga, K.4
Nakachi, K.5
-
129
-
-
0018733447
-
Natural killer cells-A new cytotoxic mechanism against tumours? Aust
-
[CrossRef] [PubMed]
-
Hersey, P. Natural killer cells-A new cytotoxic mechanism against tumours? Aust. N. Z. J. Med. 1979, 9, 464-472. [CrossRef] [PubMed]
-
(1979)
N. Z. J. Med
, vol.9
, pp. 464-472
-
-
Hersey, P.1
-
130
-
-
79952127072
-
Enhancing natural killer (NK) cell mediated killing of non-hodgkin's lymphoma
-
Srivastava, S.; Feng, H.L.; Zhang, S.H.; Liang, J.; Squiban, P.; Farag, S. Enhancing natural killer (NK) cell mediated killing of non-hodgkin's lymphoma. Blood 2009, 114, 1059-1060.
-
(2009)
Blood
, vol.114
, pp. 1059-1060
-
-
Srivastava, S.1
Feng, H.L.2
Zhang, S.H.3
Liang, J.4
Squiban, P.5
Farag, S.6
-
131
-
-
69249108787
-
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells
-
[CrossRef] [PubMed]
-
Romagne, F.; Andre, P.; Spee, P.; Zahn, S.; Anfossi, N.; Gauthier, L.; Capanni, M.; Ruggeri, L.; Benson, D.M.; Blaser, B.W.; et al. Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood 2009, 114, 2667-2677. [CrossRef] [PubMed]
-
(2009)
Blood
, vol.114
, pp. 2667-2677
-
-
Romagne, F.1
Andre, P.2
Spee, P.3
Zahn, S.4
Anfossi, N.5
Gauthier, L.6
Capanni, M.7
Ruggeri, L.8
Benson, D.M.9
Blaser, B.W.10
-
132
-
-
84934287610
-
Therapeutic potential and challenges of natural killer cells in treatment of solid tumors
-
[CrossRef] [PubMed]
-
Gras Navarro, A.; Bjorklund, A.T.; Chekenya, M. Therapeutic potential and challenges of natural killer cells in treatment of solid tumors. Front. Immunol. 2015, 6, 202. [CrossRef] [PubMed]
-
(2015)
Front. Immunol
, vol.6
, pp. 202
-
-
Gras Navarro, A.1
Bjorklund, A.T.2
Chekenya, M.3
-
133
-
-
84943543488
-
NK cells preferentially target tumor cells with a cancer stem cell phenotype
-
[CrossRef] [PubMed]
-
Ames, E.; Canter, R.J.; Grossenbacher, S.K.; Mac, S.; Chen, M.; Smith, R.C.; Hagino, T.; Perez-Cunningham, J.; Sckisel, G.D.; Urayama, S.; et al. NK cells preferentially target tumor cells with a cancer stem cell phenotype. J. Immunol. 2015, 195, 4010-4019. [CrossRef] [PubMed]
-
(2015)
J. Immunol
, vol.195
, pp. 4010-4019
-
-
Ames, E.1
Canter, R.J.2
Grossenbacher, S.K.3
Mac, S.4
Chen, M.5
Smith, R.C.6
Hagino, T.7
Perez-Cunningham, J.8
Sckisel, G.D.9
Urayama, S.10
-
134
-
-
0032535119
-
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
-
[CrossRef] [PubMed]
-
Melero, I.; Johnston, J.V.; Shufford, W.W.; Mittler, R.S.; Chen, L.P. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell. Immunol. 1998, 190, 167-172. [CrossRef] [PubMed]
-
(1998)
Cell. Immunol
, vol.190
, pp. 167-172
-
-
Melero, I.1
Johnston, J.V.2
Shufford, W.W.3
Mittler, R.S.4
Chen, L.P.5
-
135
-
-
84905970560
-
Therapeutic applications: Natural killer cells in the clinic
-
[CrossRef] [PubMed]
-
Miller, J.S. Therapeutic applications: Natural killer cells in the clinic. Hematol. Am. Soc. Hematol. Educ. Program. 2013, 2013, 247-253. [CrossRef] [PubMed]
-
(2013)
Hematol. Am. Soc. Hematol. Educ. Program
, vol.2013
, pp. 247-253
-
-
Miller, J.S.1
-
136
-
-
77958040684
-
Allogeneic natural killer cells for refractory lymphoma
-
[CrossRef] [PubMed]
-
Bachanova, V.; Burns, L.J.; McKenna, D.H.; Curtsinger, J.; Panoskaltsis-Mortari, A.; Lindgren, B.R.; Cooley, S.; Weisdorf, D.; Miller, J.S. Allogeneic natural killer cells for refractory lymphoma. Cancer Immunol. Immunother. 2010, 59, 1739-1744. [CrossRef] [PubMed]
-
(2010)
Cancer Immunol. Immunother
, vol.59
, pp. 1739-1744
-
-
Bachanova, V.1
Burns, L.J.2
McKenna, D.H.3
Curtsinger, J.4
Panoskaltsis-Mortari, A.5
Lindgren, B.R.6
Cooley, S.7
Weisdorf, D.8
Miller, J.S.9
-
137
-
-
84919431238
-
Natural killer cells for cancer immunotherapy: Pluripotent stem cells-derived NK cells as an immunotherapeutic perspective
-
[CrossRef] [PubMed]
-
Eguizabal, C.; Zenarruzabeitia, O.; Monge, J.; Santos, S.; Vesga, M.A.; Maruri, N.; Arrieta, A.; Rinon, M.; Tamayo-Orbegozo, E.; Amo, L.; et al. Natural killer cells for cancer immunotherapy: Pluripotent stem cells-derived NK cells as an immunotherapeutic perspective. Front. Immunol. 2014, 5, 439. [CrossRef] [PubMed]
-
(2014)
Front. Immunol
, vol.5
, pp. 439
-
-
Eguizabal, C.1
Zenarruzabeitia, O.2
Monge, J.3
Santos, S.4
Vesga, M.A.5
Maruri, N.6
Arrieta, A.7
Rinon, M.8
Tamayo-Orbegozo, E.9
Amo, L.10
-
138
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
[CrossRef] [PubMed]
-
Hodi, F.S.; O'Day, S.J.; McDermott, D.F.;Weber, R.W.; Sosman, J.A.; Haanen, J.B.; Gonzalez, R.; Robert, C.; Schadendorf, D.; Hassel, J.C.; et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 2010, 363, 711-723. [CrossRef] [PubMed]
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
139
-
-
84933505755
-
A phase 1 study of the bispecific anti-CD30/CD16A antibody construct AFM13 in patients with relapsed or refractory hodgkin lymphoma
-
[CrossRef] [PubMed]
-
Rothe, A.; Sasse, S.; Topp, M.S.; Eichenauer, D.A.; Hummel, H.; Reiners, K.S.; Dietlein, M.; Kuhnert, G.; Kessler, J.; Buerkle, C.; et al. A phase 1 study of the bispecific anti-CD30/CD16A antibody construct AFM13 in patients with relapsed or refractory hodgkin lymphoma. Blood 2015, 125, 4024-4031. [CrossRef] [PubMed]
-
(2015)
Blood
, vol.125
, pp. 4024-4031
-
-
Rothe, A.1
Sasse, S.2
Topp, M.S.3
Eichenauer, D.A.4
Hummel, H.5
Reiners, K.S.6
Dietlein, M.7
Kuhnert, G.8
Kessler, J.9
Buerkle, C.10
-
140
-
-
84871389574
-
Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production
-
[CrossRef] [PubMed]
-
Gleason, M.K.; Verneris, M.R.; Todhunter, D.A.; Zhang, B.; McCullar, V.; Zhou, S.X.; Panoskaltsis-Mortari, A.; Weiner, L.M.; Vallera, D.A.; Miller, J.S. Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production. Mol. Cancer Ther. 2012, 11, 2674-2684. [CrossRef] [PubMed]
-
(2012)
Mol. Cancer Ther
, vol.11
, pp. 2674-2684
-
-
Gleason, M.K.1
Verneris, M.R.2
Todhunter, D.A.3
Zhang, B.4
McCullar, V.5
Zhou, S.X.6
Panoskaltsis-Mortari, A.7
Weiner, L.M.8
Vallera, D.A.9
Miller, J.S.10
-
141
-
-
84903215048
-
CD16 × CD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets
-
[CrossRef] [PubMed]
-
Gleason, M.K.; Ross, J.A.; Warlick, E.D.; Lund, T.C.; Verneris, M.R.; Wiernik, A.; Spellman, S.; Haagenson, M.D.; Lenvik, A.J.; Litzow, M.R.; et al. CD16 × CD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets. Blood 2014, 123, 3016-3026. [CrossRef] [PubMed]
-
(2014)
Blood
, vol.123
, pp. 3016-3026
-
-
Gleason, M.K.1
Ross, J.A.2
Warlick, E.D.3
Lund, T.C.4
Verneris, M.R.5
Wiernik, A.6
Spellman, S.7
Haagenson, M.D.8
Lenvik, A.J.9
Litzow, M.R.10
-
142
-
-
84877872803
-
Heterodimeric bispecific single-chain variable-fragment antibodies against epcam and CD16 induce effective antibody-dependent cellular cytotoxicity against human carcinoma cells
-
[CrossRef] [PubMed]
-
Vallera, D.A.; Zhang, B.; Gleason, M.K.; Oh, S.; Weiner, L.M.; Kaufman, D.S.; McCullar, V.; Miller, J.S.; Verneris, M.R. Heterodimeric bispecific single-chain variable-fragment antibodies against epcam and CD16 induce effective antibody-dependent cellular cytotoxicity against human carcinoma cells. Cancer Biother. Radiopharm. 2013, 28, 274-282. [CrossRef] [PubMed]
-
(2013)
Cancer Biother. Radiopharm
, vol.28
, pp. 274-282
-
-
Vallera, D.A.1
Zhang, B.2
Gleason, M.K.3
Oh, S.4
Weiner, L.M.5
Kaufman, D.S.6
McCullar, V.7
Miller, J.S.8
Verneris, M.R.9
-
143
-
-
78651404837
-
A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting
-
[CrossRef] [PubMed]
-
Schubert, I.; Kellner, C.; Stein, C.; Kugler, M.; Schwenkert, M.; Saul, D.; Mentz, K.; Singer, H.; Stockmeyer, B.; Hillen, W.; et al. A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting. mAbs 2011, 3, 21-30. [CrossRef] [PubMed]
-
(2011)
mAbs
, vol.3
, pp. 21-30
-
-
Schubert, I.1
Kellner, C.2
Stein, C.3
Kugler, M.4
Schwenkert, M.5
Saul, D.6
Mentz, K.7
Singer, H.8
Stockmeyer, B.9
Hillen, W.10
-
144
-
-
0242362829
-
A trivalent anti-erbB2/anti-CD16 bispecific antibody retargeting NK cells against human breast cancer cells
-
[CrossRef] [PubMed]
-
Xie, Z.; Shi, M.; Feng, J.; Yu, M.; Sun, Y.; Shen, B.; Guo, N. A trivalent anti-erbB2/anti-CD16 bispecific antibody retargeting NK cells against human breast cancer cells. Biochem. Biophys. Res. Commun. 2003, 311, 307-312. [CrossRef] [PubMed]
-
(2003)
Biochem. Biophys. Res. Commun
, vol.311
, pp. 307-312
-
-
Xie, Z.1
Shi, M.2
Feng, J.3
Yu, M.4
Sun, Y.5
Shen, B.6
Guo, N.7
-
145
-
-
0034671764
-
Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives
-
[CrossRef] [PubMed]
-
Schoonjans, R.;Willems, A.; Schoonooghe, S.; Fiers, W.; Grooten, J.; Mertens, N. Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives. J. Immunol. 2000, 165, 7050-7057. [CrossRef] [PubMed]
-
(2000)
J. Immunol
, vol.165
, pp. 7050-7057
-
-
Schoonjans, R.1
Willems, A.2
Schoonooghe, S.3
Fiers, W.4
Grooten, J.5
Mertens, N.6
-
146
-
-
56449124449
-
In vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ERBB2 and CD16
-
[CrossRef] [PubMed]
-
Lu, H.; Shi, M.; Wang, M.; Xie, Z.; Hu, M.; Yu, M.; Shen, B.; Ma, Y.; Guo, N. In vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ERBB2 and CD16. Cancer Biol. Ther. 2008, 7, 1744-1750. [CrossRef] [PubMed]
-
(2008)
Cancer Biol. Ther
, vol.7
, pp. 1744-1750
-
-
Lu, H.1
Shi, M.2
Wang, M.3
Xie, Z.4
Hu, M.5
Yu, M.6
Shen, B.7
Ma, Y.8
Guo, N.9
-
147
-
-
84906241263
-
A Fc RIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy
-
[CrossRef] [PubMed]
-
Turini, M.; Chames, P.; Bruhns, P.; Baty, D.; Kerfelec, B. A Fc RIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy. Oncotarget 2014, 5, 5304-5319. [CrossRef] [PubMed]
-
(2014)
Oncotarget
, vol.5
, pp. 5304-5319
-
-
Turini, M.1
Chames, P.2
Bruhns, P.3
Baty, D.4
Kerfelec, B.5
-
148
-
-
84882241230
-
Single-domain antibody-based and linker-free bispecific antibodies targeting Fc RIII induce potent antitumor activity without recruiting regulatory T cells
-
[CrossRef] [PubMed]
-
Rozan, C.; Cornillon, A.; Petiard, C.; Chartier, M.; Behar, G.; Boix, C.; Kerfelec, B.; Robert, B.; Pelegrin, A.; Chames, P.; et al. Single-domain antibody-based and linker-free bispecific antibodies targeting Fc RIII induce potent antitumor activity without recruiting regulatory T cells. Mol. Cancer Ther. 2013, 12, 1481-1491. [CrossRef] [PubMed]
-
(2013)
Mol. Cancer Ther
, vol.12
, pp. 1481-1491
-
-
Rozan, C.1
Cornillon, A.2
Petiard, C.3
Chartier, M.4
Behar, G.5
Boix, C.6
Kerfelec, B.7
Robert, B.8
Pelegrin, A.9
Chames, P.10
-
149
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
[CrossRef] [PubMed]
-
Hamers-Casterman, C.; Atarhouch, T.; Muyldermans, S.; Robinson, G.; Hamers, C.; Songa, E.B.; Bendahman, N.; Hamers, R. Naturally occurring antibodies devoid of light chains. Nature 1993, 363, 446-448. [CrossRef] [PubMed]
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
Hamers-Casterman, C.1
Atarhouch, T.2
Muyldermans, S.3
Robinson, G.4
Hamers, C.5
Songa, E.B.6
Bendahman, N.7
Hamers, R.8
-
150
-
-
0036190672
-
Adaptive evolution of variable region genes encoding an unusual type of immunoglobulin in camelids
-
[CrossRef] [PubMed]
-
Su, C.; Nguyen, V.K.; Nei, M. Adaptive evolution of variable region genes encoding an unusual type of immunoglobulin in camelids. Mol. Biol. Evol. 2002, 19, 205-215. [CrossRef] [PubMed]
-
(2002)
Mol. Biol. Evol
, vol.19
, pp. 205-215
-
-
Su, C.1
Nguyen, V.K.2
Nei, M.3
-
151
-
-
0036182644
-
Single-domain antibody fragments with high conformational stability
-
[CrossRef] [PubMed]
-
Dumoulin, M.; Conrath, K.; Van Meirhaeghe, A.; Meersman, F.; Heremans, K.; Frenken, L.G.; Muyldermans, S.; Wyns, L.; Matagne, A. Single-domain antibody fragments with high conformational stability. Protein Sci. 2002, 11, 500-515. [CrossRef] [PubMed]
-
(2002)
Protein Sci
, vol.11
, pp. 500-515
-
-
Dumoulin, M.1
Conrath, K.2
Van Meirhaeghe, A.3
Meersman, F.4
Heremans, K.5
Frenken, L.G.6
Muyldermans, S.7
Wyns, L.8
Matagne, A.9
-
152
-
-
59149104037
-
General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold
-
[CrossRef] [PubMed]
-
Vincke, C.; Loris, R.; Saerens, D.; Martinez-Rodriguez, S.; Muyldermans, S.; Conrath, K. General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J. Biol. Chem. 2009, 284, 3273-3284. [CrossRef] [PubMed]
-
(2009)
J. Biol. Chem
, vol.284
, pp. 3273-3284
-
-
Vincke, C.1
Loris, R.2
Saerens, D.3
Martinez-Rodriguez, S.4
Muyldermans, S.5
Conrath, K.6
-
153
-
-
0035831483
-
Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs
-
[CrossRef] [PubMed]
-
Els Conrath, K.; Lauwereys, M.; Wyns, L.; Muyldermans, S. Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs. J. Biol. Chem. 2001, 276, 7346-7350. [CrossRef] [PubMed]
-
(2001)
J. Biol. Chem
, vol.276
, pp. 7346-7350
-
-
Els Conrath, K.1
Lauwereys, M.2
Wyns, L.3
Muyldermans, S.4
-
154
-
-
35148814410
-
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
-
[CrossRef] [PubMed]
-
Clark, C.E.; Hingorani, S.R.; Mick, R.; Combs, C.; Tuveson, D.A.; Vonderheide, R.H. Dynamics of the immune reaction to pancreatic cancer from inception to invasion. Cancer Res. 2007, 67, 9518-9527. [CrossRef] [PubMed]
-
(2007)
Cancer Res
, vol.67
, pp. 9518-9527
-
-
Clark, C.E.1
Hingorani, S.R.2
Mick, R.3
Combs, C.4
Tuveson, D.A.5
Vonderheide, R.H.6
-
155
-
-
39649120597
-
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells
-
[CrossRef] [PubMed]
-
Duluc, D.; Delneste, Y.; Tan, F.; Moles, M.P.; Grimaud, L.; Lenoir, J.; Preisser, L.; Anegon, I.; Catala, L.; Ifrah, N.; et al. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood 2007, 110, 4319-4330. [CrossRef] [PubMed]
-
(2007)
Blood
, vol.110
, pp. 4319-4330
-
-
Duluc, D.1
Delneste, Y.2
Tan, F.3
Moles, M.P.4
Grimaud, L.5
Lenoir, J.6
Preisser, L.7
Anegon, I.8
Catala, L.9
Ifrah, N.10
-
156
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
[CrossRef] [PubMed]
-
Lewis, C.E.; Pollard, J.W. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006, 66, 605-612. [CrossRef] [PubMed]
-
(2006)
Cancer Res
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
157
-
-
33344460032
-
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)
-
[CrossRef] [PubMed]
-
Biswas, S.K.; Gangi, L.; Paul, S.; Schioppa, T.; Saccani, A.; Sironi, M.; Bottazzi, B.; Doni, A.; Vincenzo, B.; Pasqualini, F.; et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation). Blood 2006, 107, 2112-2122. [CrossRef] [PubMed]
-
(2006)
Blood
, vol.107
, pp. 2112-2122
-
-
Biswas, S.K.1
Gangi, L.2
Paul, S.3
Schioppa, T.4
Saccani, A.5
Sironi, M.6
Bottazzi, B.7
Doni, A.8
Vincenzo, B.9
Pasqualini, F.10
-
159
-
-
47949096781
-
Cancer-related inflammation
-
[CrossRef] [PubMed]
-
Mantovani, A.; Allavena, P.; Sica, A.; Balkwill, F. Cancer-related inflammation. Nature 2008, 454, 436-444. [CrossRef] [PubMed]
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
160
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
[CrossRef] [PubMed]
-
Finak, G.; Bertos, N.; Pepin, F.; Sadekova, S.; Souleimanova, M.; Zhao, H.; Chen, H.; Omeroglu, G.; Meterissian, S.; Omeroglu, A.; et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat. Med. 2008, 14, 518-527. [CrossRef] [PubMed]
-
(2008)
Nat. Med
, vol.14
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
Sadekova, S.4
Souleimanova, M.5
Zhao, H.6
Chen, H.7
Omeroglu, G.8
Meterissian, S.9
Omeroglu, A.10
-
161
-
-
77949345555
-
Tumor-associated macrophages and survival in classic hodgkin's lymphoma
-
[CrossRef] [PubMed]
-
Steidl, C.; Lee, T.; Shah, S.P.; Farinha, P.; Han, G.; Nayar, T.; Delaney, A.; Jones, S.J.; Iqbal, J.; Weisenburger, D.D.; et al. Tumor-associated macrophages and survival in classic hodgkin's lymphoma. N. Engl. J. Med. 2010, 362, 875-885. [CrossRef] [PubMed]
-
(2010)
N. Engl. J. Med
, vol.362
, pp. 875-885
-
-
Steidl, C.1
Lee, T.2
Shah, S.P.3
Farinha, P.4
Han, G.5
Nayar, T.6
Delaney, A.7
Jones, S.J.8
Iqbal, J.9
Weisenburger, D.D.10
-
162
-
-
77956425861
-
The role of macrophages and mast cells in lymphangiogenesis and angiogenesis in cervical carcinogenesis
-
[CrossRef] [PubMed]
-
Utrera-Barillas, D.; Castro-Manrreza, M.; Castellanos, E.; Gutierrez-Rodriguez, M.; Arciniega-Ruiz de Esparza, O.; Garcia-Cebada, J.; Velazquez, J.R.; Flores-Resendiz, D.; Hernandez-Hernandez, D.; Benitez-Bribiesca, L. The role of macrophages and mast cells in lymphangiogenesis and angiogenesis in cervical carcinogenesis. Exp. Mol. Pathol. 2010, 89, 190-196. [CrossRef] [PubMed]
-
(2010)
Exp. Mol. Pathol
, vol.89
, pp. 190-196
-
-
Utrera-Barillas, D.1
Castro-Manrreza, M.2
Castellanos, E.3
Gutierrez-Rodriguez, M.4
Arciniega-Ruiz de Esparza, O.5
Garcia-Cebada, J.6
Velazquez, J.R.7
Flores-Resendiz, D.8
Hernandez-Hernandez, D.9
Benitez-Bribiesca, L.10
-
163
-
-
77949695294
-
Ratio of M2 macrophage expression is closely associated with poor prognosis for angioimmunoblastic T-cell lymphoma (AITL)
-
[CrossRef] [PubMed]
-
Niino, D.; Komohara, Y.; Murayama, T.; Aoki, R.; Kimura, Y.; Hashikawa, K.; Kiyasu, J.; Takeuchi, M.; Suefuji, N.; Sugita, Y.; et al. Ratio of M2 macrophage expression is closely associated with poor prognosis for angioimmunoblastic T-cell lymphoma (AITL). Pathol. Int. 2010, 60, 278-283. [CrossRef] [PubMed]
-
(2010)
Pathol. Int
, vol.60
, pp. 278-283
-
-
Niino, D.1
Komohara, Y.2
Murayama, T.3
Aoki, R.4
Kimura, Y.5
Hashikawa, K.6
Kiyasu, J.7
Takeuchi, M.8
Suefuji, N.9
Sugita, Y.10
-
164
-
-
0020169871
-
IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells
-
[CrossRef] [PubMed]
-
Herlyn, D.; Koprowski, H. IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells. Proc. Natl. Acad. Sci. USA 1982, 79, 4761-4765. [CrossRef] [PubMed]
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 4761-4765
-
-
Herlyn, D.1
Koprowski, H.2
-
165
-
-
0020608528
-
Human macrophages armed with murine immunoglobulin G2a antibodies to tumors destroy human cancer cells
-
[CrossRef] [PubMed]
-
Steplewski, Z.; Lubeck, M.D.; Koprowski, H. Human macrophages armed with murine immunoglobulin G2a antibodies to tumors destroy human cancer cells. Science 1983, 221, 865-867. [CrossRef] [PubMed]
-
(1983)
Science
, vol.221
, pp. 865-867
-
-
Steplewski, Z.1
Lubeck, M.D.2
Koprowski, H.3
-
166
-
-
0021235584
-
Tumors undergoing rejection induced by monoclonal antibodies of the IgG2a isotype contain increased numbers of macrophages activated for a distinctive form of antibody-dependent cytolysis
-
[CrossRef] [PubMed]
-
Adams, D.O.; Hall, T.; Steplewski, Z.; Koprowski, H. Tumors undergoing rejection induced by monoclonal antibodies of the IgG2a isotype contain increased numbers of macrophages activated for a distinctive form of antibody-dependent cytolysis. Proc. Natl. Acad. Sci. USA 1984, 81, 3506-3510. [CrossRef] [PubMed]
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 3506-3510
-
-
Adams, D.O.1
Hall, T.2
Steplewski, Z.3
Koprowski, H.4
-
167
-
-
33645218704
-
Engineered antibody Fc variants with enhanced effector function
-
[CrossRef] [PubMed]
-
Lazar, G.A.; Dang, W.; Karki, S.; Vafa, O.; Peng, J.S.; Hyun, L.; Chan, C.; Chung, H.S.; Eivazi, A.; Yoder, S.C.; et al. Engineered antibody Fc variants with enhanced effector function. Proc. Natl. Acad. Sci. USA 2006, 103, 4005-4010. [CrossRef] [PubMed]
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 4005-4010
-
-
Lazar, G.A.1
Dang, W.2
Karki, S.3
Vafa, O.4
Peng, J.S.5
Hyun, L.6
Chan, C.7
Chung, H.S.8
Eivazi, A.9
Yoder, S.C.10
-
168
-
-
0029095589
-
Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu
-
[PubMed]
-
Valone, F.H.; Kaufman, P.A.; Guyre, P.M.; Lewis, L.D.; Memoli, V.; Deo, Y.; Graziano, R.; Fisher, J.L.; Meyer, L.; Mrozek-Orlowski, M.; et al. Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu. J. Clin. Oncol. 1995, 13, 2281-2292. [PubMed]
-
(1995)
J. Clin. Oncol
, vol.13
, pp. 2281-2292
-
-
Valone, F.H.1
Kaufman, P.A.2
Guyre, P.M.3
Lewis, L.D.4
Memoli, V.5
Deo, Y.6
Graziano, R.7
Fisher, J.L.8
Meyer, L.9
Mrozek-Orlowski, M.10
-
169
-
-
0032944540
-
Antibody dependent cellular phagocytosis (ADCP) and antibody dependent cellular cytotoxicity (ADCC) of breast cancer cells mediated by bispecific antibody, MDX-210
-
[CrossRef] [PubMed]
-
Watanabe, M.;Wallace, P.K.; Keler, T.; Deo, Y.M.; Akewanlop, C.; Hayes, D.F. Antibody dependent cellular phagocytosis (ADCP) and antibody dependent cellular cytotoxicity (ADCC) of breast cancer cells mediated by bispecific antibody, MDX-210. Breast Cancer Res. Treat. 1999, 53, 199-207. [CrossRef] [PubMed]
-
(1999)
Breast Cancer Res. Treat
, vol.53
, pp. 199-207
-
-
Watanabe, M.1
Wallace, P.K.2
Keler, T.3
Deo, Y.M.4
Akewanlop, C.5
Hayes, D.F.6
-
170
-
-
0034940408
-
A phase II study of the bispecific antibody MDX-h210 (anti-HER2 × CD64) with GM-CSF in Her2+ advanced prostate cancer
-
[CrossRef] [PubMed]
-
James, N.D.; Atherton, P.J.; Jones, J.; Howie, A.J.; Tchekmedyian, S.; Curnow, R.T. A phase II study of the bispecific antibody MDX-h210 (anti-HER2 × CD64) with GM-CSF in Her2+ advanced prostate cancer. Br. J. Cancer 2001, 85, 152-156. [CrossRef] [PubMed]
-
(2001)
Br. J. Cancer
, vol.85
, pp. 152-156
-
-
James, N.D.1
Atherton, P.J.2
Jones, J.3
Howie, A.J.4
Tchekmedyian, S.5
Curnow, R.T.6
-
171
-
-
36348965935
-
A phase-I trial of the epidermal growth factor receptor directed bispecific antibody MDX-447 without and with recombinant human granulocyte-colony stimulating factor in patients with advanced solid tumors
-
[CrossRef] [PubMed]
-
Fury, M.G.; Lipton, A.; Smith, K.M.;Winston, C.B.; Pfister, D.G. A phase-I trial of the epidermal growth factor receptor directed bispecific antibody MDX-447 without and with recombinant human granulocyte-colony stimulating factor in patients with advanced solid tumors. Cancer Immunol. Immunother. 2008, 57, 155-163. [CrossRef] [PubMed]
-
(2008)
Cancer Immunol. Immunother
, vol.57
, pp. 155-163
-
-
Fury, M.G.1
Lipton, A.2
Smith, K.M.3
Winston, C.B.4
Pfister, D.G.5
-
172
-
-
84879733796
-
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
-
[CrossRef] [PubMed]
-
Tseng, D.; Volkmer, J.P.; Willingham, S.B.; Contreras-Trujillo, H.; Fathman, J.W.; Fernhoff, N.B.; Seita, J.; Inlay, M.A.; Weiskopf, K.; Miyanishi, M.; et al. Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response. Proc. Natl. Acad. Sci. USA 2013, 110, 11103-11108. [CrossRef] [PubMed]
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 11103-11108
-
-
Tseng, D.1
Volkmer, J.P.2
Willingham, S.B.3
Contreras-Trujillo, H.4
Fathman, J.W.5
Fernhoff, N.B.6
Seita, J.7
Inlay, M.A.8
Weiskopf, K.9
Miyanishi, M.10
-
173
-
-
84954316938
-
A bispecific antibody targeting CD47 and CD20 selectively binds and eliminates dual antigen expressing lymphoma cells
-
[CrossRef] [PubMed]
-
Piccione, E.C.; Juarez, S.; Liu, J.; Tseng, S.; Ryan, C.E.; Narayanan, C.; Wang, L.; Weiskopf, K.; Majeti, R. A bispecific antibody targeting CD47 and CD20 selectively binds and eliminates dual antigen expressing lymphoma cells. mAbs 2015, 7, 946-956. [CrossRef] [PubMed]
-
(2015)
mAbs
, vol.7
, pp. 946-956
-
-
Piccione, E.C.1
Juarez, S.2
Liu, J.3
Tseng, S.4
Ryan, C.E.5
Narayanan, C.6
Wang, L.7
Weiskopf, K.8
Majeti, R.9
-
174
-
-
35948977323
-
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
-
[CrossRef] [PubMed]
-
Wu, C.; Ying, H.; Grinnell, C.; Bryant, S.; Miller, R.; Clabbers, A.; Bose, S.; McCarthy, D.; Zhu, R.R.; Santora, L.; et al. Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin. Nat. Biotechnol. 2007, 25, 1290-1297. [CrossRef] [PubMed]
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 1290-1297
-
-
Wu, C.1
Ying, H.2
Grinnell, C.3
Bryant, S.4
Miller, R.5
Clabbers, A.6
Bose, S.7
McCarthy, D.8
Zhu, R.R.9
Santora, L.10
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