메뉴 건너뛰기




Volumn 43, Issue 6, 2006, Pages 763-771

Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells

Author keywords

Bispecific antibody; Cytolytic synapse; Cytotoxic T cell

Indexed keywords

COMPLEMENTARY DNA; EPITHELIAL CELL ADHESION MOLECULE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

EID: 28944434529     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.03.007     Document Type: Article
Times cited : (283)

References (37)
  • 1
    • 0034005120 scopus 로고    scopus 로고
    • Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition
    • P. Anton van der Merwe, S.J. Davis, A.S. Shaw, and M.L. Dustin Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition Semin. Immunol. 12 2000 5 21
    • (2000) Semin. Immunol. , vol.12 , pp. 5-21
    • Anton Van Der Merwe, P.1    Davis, S.J.2    Shaw, A.S.3    Dustin, M.L.4
  • 2
    • 12344289903 scopus 로고    scopus 로고
    • EpCAM: A new therapeutic target for an old cancer antigen
    • A. Armstrong, and S.L. Eck EpCAM: A new therapeutic target for an old cancer antigen Cancer Biol. Ther. 2 2003 320 326
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 320-326
    • Armstrong, A.1    Eck, S.L.2
  • 5
    • 0033776138 scopus 로고    scopus 로고
    • CD2 (OKT11) augments CD3-mediated intracellular signaling events in human T lymphocytes
    • S.M. Berney, T. Schaan, R.E. Wolf, H. van der Heyde, and T.P. Atkinson CD2 (OKT11) augments CD3-mediated intracellular signaling events in human T lymphocytes J. Investig. Med. 48 2000 102 109
    • (2000) J. Investig. Med. , vol.48 , pp. 102-109
    • Berney, S.M.1    Schaan, T.2    Wolf, R.E.3    Van Der Heyde, H.4    Atkinson, T.P.5
  • 6
    • 0036095702 scopus 로고    scopus 로고
    • Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: A novel protective mechanism for tumor cells to circumvent the immune system?
    • B.A. Bladergroen, C.J. Meijer, R.L. ten Berge, C.E. Hack, J.J. Muris, D.F. Dukers, A. Chott, Y. Ka-zama, J.J. Oudejans, O. van Berkum, and J.A. Kummer Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system? Blood 99 2002 232 237
    • (2002) Blood , vol.99 , pp. 232-237
    • Bladergroen, B.A.1    Meijer, C.J.2    Ten Berge, R.L.3    Hack, C.E.4    Muris, J.J.5    Dukers, D.F.6    Chott, A.7    Ka-Zama, Y.8    Oudejans, J.J.9    Van Berkum, O.10    Kummer, J.A.11
  • 8
    • 0345801302 scopus 로고    scopus 로고
    • Tumour MHC class I downregulation and immunotherapy (Review)
    • J. Bubenik Tumour MHC class I downregulation and immunotherapy (Review) Oncol Rep 10 2003 2005 2008
    • (2003) Oncol Rep , vol.10 , pp. 2005-2008
    • Bubenik, J.1
  • 10
    • 0037446782 scopus 로고    scopus 로고
    • T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3- bispecific single-chain antibody construct
    • T. Dreier, P.A. Baeuerle, I. Fichtner, M. Grun, B. Schlereth, G. Lorenczewski, P. Kufer, R. Lutterbuse, G. Riethmuller, P. Gjorstrup, and R.C. Bargou T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3- bispecific single-chain antibody construct J. Immunol. 170 2003 4397 4402
    • (2003) J. Immunol. , vol.170 , pp. 4397-4402
    • Dreier, T.1    Baeuerle, P.A.2    Fichtner, I.3    Grun, M.4    Schlereth, B.5    Lorenczewski, G.6    Kufer, P.7    Lutterbuse, R.8    Riethmuller, G.9    Gjorstrup, P.10    Bargou, R.C.11
  • 12
    • 0038240981 scopus 로고    scopus 로고
    • Coordination of T cell activation and migration through formation of the immunological synapse
    • M.L. Dustin Coordination of T cell activation and migration through formation of the immunological synapse Ann. NY Acad. Sci. 987 2003 51 59
    • (2003) Ann. NY Acad. Sci. , vol.987 , pp. 51-59
    • Dustin, M.L.1
  • 13
    • 0345257150 scopus 로고    scopus 로고
    • Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: Manifestation of a dual activation threshold
    • M. Faroudi, C. Utzny, M. Salio, V. Cerundolo, M. Guiraud, S. Muller, and S. Valitutti Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold Proc. Natl. Acad. Sci. U.S.A. 100 2003 14145 14150
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 14145-14150
    • Faroudi, M.1    Utzny, C.2    Salio, M.3    Cerundolo, V.4    Guiraud, M.5    Muller, S.6    Valitutti, S.7
  • 14
    • 0034770605 scopus 로고    scopus 로고
    • Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells
    • L. Gorelik, and R.A. Flavell Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells Nat. Med. 7 2001 1118 1122
    • (2001) Nat. Med. , vol.7 , pp. 1118-1122
    • Gorelik, L.1    Flavell, R.A.2
  • 15
    • 0037590956 scopus 로고    scopus 로고
    • Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85
    • N.J. Hutchings, N. Clarkson, R. Chalkley, A.N. Barclay, and M.H. Brown Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85 J. Biol. Chem. 278 2003 22396 22403
    • (2003) J. Biol. Chem. , vol.278 , pp. 22396-22403
    • Hutchings, N.J.1    Clarkson, N.2    Chalkley, R.3    Barclay, A.N.4    Brown, M.H.5
  • 17
    • 0023266351 scopus 로고
    • The specific direct interaction of helper T cells and antigen-presenting B cells II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells
    • A. Kupfer, S.L. Swain, and S.J. Singer The specific direct interaction of helper T cells and antigen-presenting B cells II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells J. Exp. Med. 165 1987 1565 1580
    • (1987) J. Exp. Med. , vol.165 , pp. 1565-1580
    • Kupfer, A.1    Swain, S.L.2    Singer, S.J.3
  • 21
    • 0034624809 scopus 로고    scopus 로고
    • Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes
    • O. Leupin, R. Zaru, T. Laroche, S. Muller, and S. Valitutti Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes Curr. Biol. 10 2000 277 280
    • (2000) Curr. Biol. , vol.10 , pp. 277-280
    • Leupin, O.1    Zaru, R.2    Laroche, T.3    Muller, S.4    Valitutti, S.5
  • 23
    • 0343415665 scopus 로고    scopus 로고
    • A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes
    • A. Loffler, P. Kufer, R. Lutterbuse, F. Zettl, P.T. Daniel, J.M. Schwenkenbecher, G. Riethmuller, B. Dorken, and R.C. Bargou A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes Blood 95 2000 2098 2103
    • (2000) Blood , vol.95 , pp. 2098-2103
    • Loffler, A.1    Kufer, P.2    Lutterbuse, R.3    Zettl, F.4    Daniel, P.T.5    Schwenkenbecher, J.M.6    Riethmuller, G.7    Dorken, B.8    Bargou, R.C.9
  • 24
    • 0031569465 scopus 로고    scopus 로고
    • Biologic properties of a bispecific single-chain antibody directed against 17-1A (EpCAM) and CD3: Tumor cell-dependent T cell stimulation and cytotoxic activity
    • M. Mack, R. Gruber, S. Schmidt, G. Riethmuller, and P. Kufer Biologic properties of a bispecific single-chain antibody directed against 17-1A (EpCAM) and CD3: tumor cell-dependent T cell stimulation and cytotoxic activity J. Immunol. 158 1997 3965 3970
    • (1997) J. Immunol. , vol.158 , pp. 3965-3970
    • MacK, M.1    Gruber, R.2    Schmidt, S.3    Riethmuller, G.4    Kufer, P.5
  • 25
    • 0029148633 scopus 로고
    • A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
    • M. Mack, G. Riethmuller, and P. Kufer A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity Proc Natl. Acad. Sci. USA 92 1995 7021 7025
    • (1995) Proc Natl. Acad. Sci. USA , vol.92 , pp. 7021-7025
    • MacK, M.1    Riethmuller, G.2    Kufer, P.3
  • 26
    • 0025012646 scopus 로고
    • The regulation of exogenous and endogenous class I MHC genes in a human tumor cell line, K562
    • R.T. Maziarz, S.J. Burakoff, and D.V. Faller The regulation of exogenous and endogenous class I MHC genes in a human tumor cell line, K562 Mol. Immunol. 27 1990 135 142
    • (1990) Mol. Immunol. , vol.27 , pp. 135-142
    • Maziarz, R.T.1    Burakoff, S.J.2    Faller, D.V.3
  • 29
    • 3042694110 scopus 로고    scopus 로고
    • Formation of a central supramolecu-lar activation cluster is not required for activation of naive CD8+ T cells
    • J.P. O'Keefe, K. Blaine, M.L. Alegre, and T.F. Gajewski Formation of a central supramolecu-lar activation cluster is not required for activation of naive CD8+ T cells Proc. Natl. Acad. Sci. U.S.A. 101 2004 9351 9356
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 9351-9356
    • O'Keefe, J.P.1    Blaine, K.2    Alegre, M.L.3    Gajewski, T.F.4
  • 31
    • 0022541220 scopus 로고
    • Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones
    • S. Shaw, G.E. Luce, R. Quinones, R.E. Gress, T.A. Springer, and M.E. Sanders Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones Nature 323 1986 262 264
    • (1986) Nature , vol.323 , pp. 262-264
    • Shaw, S.1    Luce, G.E.2    Quinones, R.3    Gress, R.E.4    Springer, T.A.5    Sanders, M.E.6
  • 34
    • 0035655587 scopus 로고    scopus 로고
    • The immunological synapse of CTL contains a secretory domain and membrane bridges
    • J.C. Stinchcombe, G. Bossi, S. Booth, and G.M. Griffiths The immunological synapse of CTL contains a secretory domain and membrane bridges Immunity 15 2001 751 761
    • (2001) Immunity , vol.15 , pp. 751-761
    • Stinchcombe, J.C.1    Bossi, G.2    Booth, S.3    Griffiths, G.M.4
  • 35
    • 0033759326 scopus 로고    scopus 로고
    • Loss of B7.2 (CD86) and intracellular adhesion molecule 1 (CD54) expression is associated with decreased tumor-infiltrating T lymphocytes in diffuse B-cell large-cell lym-phoma
    • A.T. Stopeck, A. Gessner, T.P. Miller, E.M. Hersh, C.S. Johnson, H. Cui, Y. Frutiger, and T.M. Grogan Loss of B7.2 (CD86) and intracellular adhesion molecule 1 (CD54) expression is associated with decreased tumor-infiltrating T lymphocytes in diffuse B-cell large-cell lym-phoma Clin. Cancer Res. 6 2000 3904 3909
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3904-3909
    • Stopeck, A.T.1    Gessner, A.2    Miller, T.P.3    Hersh, E.M.4    Johnson, C.S.5    Cui, H.6    Frutiger, Y.7    Grogan, T.M.8
  • 36
    • 0034850150 scopus 로고    scopus 로고
    • Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production
    • M. Urosevic, M.O. Kurrer, J. Kamarashev, B. Mueller, W. Weder, G. Burg, R.A. Stahel, R. Dummer, and A. Trojan Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production Am. J. Pathol. 159 2001 817 824
    • (2001) Am. J. Pathol. , vol.159 , pp. 817-824
    • Urosevic, M.1    Kurrer, M.O.2    Kamarashev, J.3    Mueller, B.4    Weder, W.5    Burg, G.6    Stahel, R.A.7    Dummer, R.8    Trojan, A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.