Migratory DCs activate TGF-b to precondition naïve CD8+T cells for tissue-resident memory fate

Science

Volumn 366, Issue 6462, 2019, Pages

  Mani, Vinidhra ^a,b   Bromley, Shannon K ^a,b   Äijö, Tarmo ^c   Mora Buch, Rut ^a,b   Carrizosa, Esteban ^a,b,d   Warner, Ross D ^a   Hamze, Moustafa ^a,b   Sen, Debattama R ^b,e   Chasse, Alexandra Y ^a   Lorant, Alina ^f   Griffith, Jason W ^a,b   Rahimi, Rod A ^a,b   McEntee, Craig P ^g   Jeffrey, Kate L ^a,b   Marangoni, Francesco ^a,b,h   Travis, Mark A ^g   Lacy Hulbert, Adam ^f   Luster, Andrew D ^a,b   Mempel, Thorsten R ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c FLATIRON INSTITUTE   (United States)

^d BLUEBIRD BIO   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f BENAROYA RESEARCH INSTITUTE   (United States)

^g UNIVERSITY OF MANCHESTER   (United Kingdom)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; CD51 ANTIGEN; DNA VACCINE; FINGOLIMOD; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN; TRANSFORMING GROWTH FACTOR BETA;

CELL COMPONENT; DIFFERENTIATION; IMMUNE RESPONSE; IMMUNE SYSTEM; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY; PATHOGEN; PROTEIN; SKIN; VACCINATION;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; DENDRITIC CELL; DNA IMMUNIZATION; IMMUNE SYSTEM; IMMUNOGLOBULIN BLOOD LEVEL; LYMPH NODE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PSORIASIS; SKIN IRRITATION; ANIMAL; C57BL MOUSE; CELL MOTION; EPIDERMIS; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; SKIN; TRANSGENIC MOUSE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; DENDRITIC CELLS; EPIDERMIS; IMMUNOLOGIC MEMORY; INTEGRIN ALPHAV; LYMPH NODES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SKIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 85073111444     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aav5728     Document Type: Article

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