A single glycan on IgE is indispensable for initiation of anaphylaxis

Journal of Experimental Medicine

Volumn 212, Issue 4, 2015, Pages 457-467

  Shade, Kai Ting C ^a   Platzer, Barbara ^a   Washburn, Nathaniel ^b   Mani, Vinidhra ^a   Bartsch, Yannic C ^a   Conroy, Michelle ^a   Pagan, Jose D ^a   Bosques, Carlos ^b   Mempel, Thorsten R ^a   Fiebiger, Edda ^a   Anthony, Robert M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Momenta Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; FC EPSILON RECEPTOR I; FC RECEPTOR; GLYCAN; IMMUNOGLOBULIN E; MANNOSE OLIGOSACCHARIDE; UNCLASSIFIED DRUG; AUTACOID; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOGLOBULIN E RECEPTOR; POLYSACCHARIDE;

ALLERGIC DISEASE; ALLERGIC REACTION; ANAPHYLAXIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ARTICLE; CELLULAR DISTRIBUTION; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONSENSUS SEQUENCE; CONTROLLED STUDY; DEGLYCOSYLATION; DIMERIZATION; FEMALE; FLOW CYTOMETRY; GLYCOSYLATION; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; ANIMAL; BAGG ALBINO MOUSE; DEGRANULATION; GENETICS; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANAPHYLAXIS; ANIMALS; CELL DEGRANULATION; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN E; INFLAMMATION MEDIATORS; MAST CELLS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; POLYSACCHARIDES; RECEPTORS, IGE;

EID: 84928253650     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20142182     Document Type: Article

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