A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System

Cell

Volumn 174, Issue 1, 2018, Pages 156-171.e16

  Qin, Yan ^a,b   Garrison, Brian S ^a,c   Ma, Wenjiang ^a,b   Wang, Rui ^a,b   Jiang, Aiping ^a,b   Li, Jing ^a,b   Mistry, Meeta ^d   Bronson, Roderick T ^b   Santoro, Daria ^a,b   Franco, Charlotte ^a,b   Robinton, Daisy A ^a,b   Stevens, Beth ^a,b   Rossi, Derrick J ^a,c   Lu, Chafen ^a,b   Springer, Timothy A ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Harvard University   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

integrins; LRRC33; microglia; milieu molecules; TGF

Indexed keywords

ALPHAVBETA8 INTEGRIN; LEUCINE RICH REPEAT CONTAINING PROTEIN 33; RECEPTOR; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CARRIER PROTEIN; INTEGRIN; INTEGRIN ALPHAVBETA8; PROTEIN BINDING; PROTEIN PRECURSOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; BRAIN; CELL FUNCTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; DISEASE EXACERBATION; MACROPHAGE; MICROGLIA; MOTOR CORTEX; MOUSE; NERVOUS SYSTEM; NONHUMAN; PARAPLEGIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SPINAL CORD; ANIMAL; AXON; C57BL MOUSE; CELL CULTURE; CLASSIFICATION; CYTOLOGY; DEGENERATIVE DISEASE; GENETICS; IMMUNOLOGY; KAPLAN MEIER METHOD; KNOCKOUT MOUSE; METABOLISM; MORTALITY; PATHOLOGY; PHYLOGENY; SITE DIRECTED MUTAGENESIS;

ANIMALS; AXONS; BONE MARROW TRANSPLANTATION; BRAIN; CARRIER PROTEINS; CELLS, CULTURED; INTEGRINS; KAPLAN-MEIER ESTIMATE; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MUTAGENESIS, SITE-DIRECTED; NERVOUS SYSTEM; NEURODEGENERATIVE DISEASES; PHYLOGENY; PROTEIN BINDING; PROTEIN PRECURSORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 85048310919     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.05.027     Document Type: Article

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