Modeling and Structural Characterization of the Sweet Taste Receptor Heterodimer

ACS Chemical Neuroscience

Volumn 10, Issue 11, 2019, Pages 4579-4592

  Perez Aguilar, Jose Manuel ^a,b   Kang, Seung Gu ^a   Zhang, Leili ^a   Zhou, Ruhong ^a  

^a IBM T J WATSON RESEARCH CENTER   (United States)

^b BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

Author keywords

allosteric binding sites; GPCR; heterodimer; molecular dynamics; Sweet taste receptor; T1R2 T1R3 full length model

Indexed keywords

CHOLESTEROL; G PROTEIN COUPLED RECEPTOR; HETERODIMER; RECEPTOR; SODIUM ION; SWEET TASTE RECEPTOR; T1R2 RECEPTOR; T1R3 RECEPTOR; UNCLASSIFIED DRUG; ION; PROTEIN BINDING; SODIUM; TASTE RECEPTORS, TYPE 1; WATER;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STATIC ELECTRICITY; CHEMISTRY; COMPUTER SIMULATION; DIMERIZATION; EXTRACELLULAR SPACE; INTRACELLULAR SPACE; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; CHOLESTEROL; COMPUTER SIMULATION; DIMERIZATION; EXTRACELLULAR SPACE; HUMANS; INTRACELLULAR SPACE; IONS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAINS; RECEPTORS, G-PROTEIN-COUPLED; SODIUM; WATER;

EID: 85072997569     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.9b00438     Document Type: Article

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