Structural mechanism of ligand activation in human calcium-sensing receptor

eLife

Volumn 5, Issue JULY, 2016, Pages

  Geng, Yong ^a,b   Mosyak, Lidia ^a   Kurinov, Igor ^c   Zuo, Hao ^a   Sturchler, Emmanuel ^d   Cheng, Tat Cheung ^a   Subramanyam, Prakash ^a   Brown, Alice P ^e   Brennan, Sarah C ^e   Mun, Hee Chang ^e   Bush, Martin ^a   Chen, Yan ^a   Nguyen, Trang X ^a   Cao, Baohua ^a   Chang, Donald D ^a   Quick, Matthias ^a   Conigrave, Arthur D ^e   Colecraft, Henry M ^a   McDonald, Patricia ^d   Fan, Qing R ^a,f  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c Department of Obstetrics Gynecology   (United States)

^d SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE   (United States)

^e UNIVERSITY OF SYDNEY   (Australia)

^f NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SENSING RECEPTOR; G PROTEIN COUPLED RECEPTOR; HOMODIMER; INOSITOL PHOSPHATE; LIGAND; CALCIUM; PHOSPHATE; PROTEIN BINDING; TRYPTOPHAN;

ARTICLE; CALCIUM BINDING; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CRYSTALLIZATION; ENZYME GLYCOSYLATION; GEL FILTRATION CHROMATOGRAPHY; GENE EXPRESSION REGULATION; HUMAN; ION EXCHANGE CHROMATOGRAPHY; MICROFLUOROMETRY; PARATHYROID HORMONE RELEASE; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SCINTILLATION; SIGNAL TRANSDUCTION; AGONISTS; BINDING SITE; CHEMISTRY; METABOLISM; MOLECULAR MODEL; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CALCIUM; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; PHOSPHATES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RECEPTORS, CALCIUM-SENSING; TRYPTOPHAN;

EID: 84983057081     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.13662     Document Type: Article

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