A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

Nature Communications

Volumn 10, Issue 1, 2019, Pages

  Liang, Mindong ^a,b   Li, Zilong ^c   Wang, Weishan ^c   Liu, Jiakun ^a,d   Liu, Leshi ^a   Zhu, Guoliang ^a   Karthik, Loganathan ^a   Wang, Man ^e   Wang, Ke Feng ^a   Wang, Zhong ^f   Yu, Jing ^f   Shuai, Yuting ^a   Yu, Jiaming ^a   Zhang, Lu ^a   Yang, Zhiheng ^a   Li, Chuan ^a   Zhang, Qian ^a   Shi, Tong ^a   Zhou, Liming ^a   Xie, Feng ^c   Dai, Huanqin ^c   Liu, Xueting ^a   Zhang, Jingyu ^a   Liu, Guang ^a   Zhuo, Ying ^a   Zhang, Buchang ^b   Liu, Chenli ^d   Li, Shanshan ^g   Xia, Xuekui ^h   Tong, Yaojun ⁱ   Liu, Yanwen ^j   Alterovitz, Gil ^k   Tan, Gao Yi ^a   Zhang, Li Xin ^a   more..

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b ANHUI UNIVERSITY   (China)

^c INSTITUTE OF MICROBIOLOGY   (China)

^d SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

^e SHANGHAI JIAO TONG UNIVERSITY   (China)

^f SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^g INSTITUTE OF PLANT PROTECTION   (China)

^h QILU UNIVERSITY OF TECHNOLOGY   (China)

ⁱ Chalmers University of Technology   (Denmark)

^j inBiome Sciences   (United States)

^k HARVARD MEDICAL SCHOOL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBENZOIC ACID; DOUBLE STRANDED DNA; SINGLE STRANDED DNA; TRANSCRIPTION FACTOR; URIC ACID; 4 HYDROXYBENZOIC ACID ESTER; 4-HYDROXYBENZOIC ACID; CRISPR ASSOCIATED PROTEIN; DEOXYRIBONUCLEASE;

BLOOD; CHEMICAL COMPOUND; CONCENTRATION (COMPOSITION); DNA; GENOME; MOLECULAR ANALYSIS; PROTEIN;

ARTICLE; BINDING AFFINITY; BLOOD SAMPLING; CRISPR CAS SYSTEM; LACHNOSPIRACEAE; NONHUMAN; ALLOSTERISM; BIOASSAY; BLOOD; CLOSTRIDIALES; HUMAN; LIMIT OF DETECTION; NUCLEOTIDE MOTIF; SYNTHETIC BIOLOGY;

BACTERIA (MICROORGANISMS);

ALLOSTERIC REGULATION; BIOLOGICAL ASSAY; CLOSTRIDIALES; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; ENDODEOXYRIBONUCLEASES; HUMANS; LIMIT OF DETECTION; NUCLEOTIDE MOTIFS; PARABENS; SYNTHETIC BIOLOGY; TRANSCRIPTION FACTORS; URIC ACID;

EID: 85070762443     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-019-11648-1     Document Type: Article

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