Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system

Nature Structural Biology

Volumn 7, Issue 3, 2000, Pages 215-219

  Orth, Peter ^a   Schnappinger, Dirk ^b   Hillen, Wolfgang ^b   Saenger, Wolfram ^a   Hinrichs, Winfried ^a,c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MAGNESIUM DERIVATIVE; REPRESSOR PROTEIN; TETRACYCLINE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; DNA STRUCTURE; GENE CONTROL; GRAM NEGATIVE BACTERIUM; HYDROGEN BOND; OPERATOR GENE; PRIORITY JOURNAL; REPRESSOR GENE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA-BINDING PROTEINS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; OPERATOR REGIONS (GENETICS); PROTEIN CONFORMATION; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TETRACYCLINE;

BACTERIA (MICROORGANISMS); EUKARYOTA; NEGIBACTERIA;

EID: 0034087676     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/73324     Document Type: Article

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