Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

Immunity

Volumn 51, Issue 2, 2019, Pages 285-297.e5

  Bachem, Annabell ^a   Makhlouf, Christina ^a   Binger, Katrina J ^a   de Souza, David P ^a   Tull, Deidra ^a   Hochheiser, Katharina ^a   Whitney, Paul G ^a   Fernandez Ruiz, Daniel ^a   Dähling, Sabrina ^a   Kastenmüller, Wolfgang ^b   Jönsson, Johanna ^a   Gressier, Elise ^a   Lew, Andrew M ^c   Perdomo, Carolina ^d   Kupz, Andreas ^d,e   Figgett, William ^a   Mackay, Fabienne ^a   Oleshansky, Moshe ^f   Russ, Brendan E ^f   Parish, Ian A ^g   Kallies, Axel ^a   McConville, Malcolm J ^a   Turner, Stephen J ^f   Gebhardt, Thomas ^a   Bedoui, Sammy ^a   more..

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^e JAMES COOK UNIVERSITY   (Australia)

^f MONASH UNIVERSITY   (Australia)

^g PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

butyrate; CD8+ T cells; fatty acid oxidation; memory differentiation; microbiota; short chain fatty acids; T cell metabolism

Indexed keywords

BUTYRIC ACID; FATTY ACID; GLUTAMINE; SHORT CHAIN FATTY ACID; ANTIGEN; BUTYRIC ACID DERIVATIVE; VOLATILE FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATABOLISM; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL METABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; DIET; GLYCOLYSIS; LONG TERM SURVIVAL; MEMORY CELL; MICROFLORA; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; ADOPTIVE TRANSFER; ANIMAL; C57BL MOUSE; CELL CULTURE; HUMAN; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; OXIDATION REDUCTION REACTION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS; BUTYRATES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; FATTY ACIDS, VOLATILE; GLYCOLYSIS; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROBIOTA; OXIDATION-REDUCTION;

EID: 85070719138     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2019.06.002     Document Type: Article

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