Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1

Cell Host and Microbe

Volumn 25, Issue 5, 2019, Pages 706-718.e7

  Liang, Shaonan ^a,b   Guo, Xue Kun ^a,b   Ou, Jiayao ^a,b   Huang, Rongyao ^b   Xue, Qing ^b   Zhang, Bin ^a,b   Chung, Yeonseok ^c   Wu, Wei ^b   Dong, Chen ^a,b   Yang, Xuerui ^b   Hu, Xiaoyu ^a,b  

^a Tsinghua University   (China)

^b TSINGHUA UNIVERSITY   (China)

^c Seoul National University   (South Korea)

Author keywords

antimicrobial proteins; enteric infection; Hes1; intestinal epithelial cell; nutrient sensing; defensins

Indexed keywords

ALPHA DEFENSIN; MAMMALIAN TARGET OF RAPAMYCIN; MATRILYSIN; TRANSCRIPTION FACTOR HES 1; HES1 PROTEIN, MOUSE; MMP7 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; FEMALE; INTESTINE EPITHELIUM CELL; INTESTINE FLORA; INTESTINE INFECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STARVATION; TRANSCRIPTION INITIATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; DRUG EFFECT; EPITHELIUM CELL; GENE EXPRESSION REGULATION; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; MUCOSAL IMMUNITY;

ALPHA-DEFENSINS; ANIMALS; CELL LINE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; MATRIX METALLOPROTEINASE 7; MICE, INBRED C57BL; NUTRIENTS; TRANSCRIPTION FACTOR HES-1;

EID: 85064891576     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2019.03.012     Document Type: Article

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