Activation of GPR55 induces neuroprotection of hippocampal neurogenesis and immune responses of neural stem cells following chronic, systemic inflammation

Brain, Behavior, and Immunity

Volumn 76, Issue , 2019, Pages 165-181

  Hill, Jeremy D ^a   Zuluaga Ramirez, Viviana ^a   Gajghate, Sachin ^a   Winfield, Malika ^a   Sriram, Uma ^a   Rom, Slava ^a   Persidsky, Yuri ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cannabinoid; GPR55; Hippocampus; Inflammation; Neural stem cell; Neurogenesis; Neuroprotection

Indexed keywords

4 (6 ISOPROPENYL 3 METHYL 2 CYCLOHEXENYL) 5 METHYLRESORCINOL; BETA TUBULIN; G PROTEIN COUPLED RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GPR55 PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NESTIN; PROTEIN S100B; TRANSCRIPTION FACTOR SOX2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CANNABIDIOL; CANNABINOID RECEPTOR; GPR55 PROTEIN, MOUSE; O-1602 COMPOUND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROBLAST; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; ACTIVE IMMUNIZATION; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; DRUG EFFECT; GENETICS; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CANNABIDIOL; CELL DIFFERENTIATION; FEMALE; HIPPOCAMPUS; IMMUNITY, ACTIVE; INFLAMMATION; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; NEUROPROTECTION; RECEPTORS, CANNABINOID;

EID: 85057015929     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2018.11.017     Document Type: Article

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