-
2
-
-
0003518480
-
-
Wiley Interscience, New York
-
Segel, I. H., Enzyme Kinetics, Wiley Interscience, New York, 1975.
-
(1975)
Enzyme Kinetics
-
-
Segel, I.H.1
-
3
-
-
0002030194
-
Catalytic power and transition-state stabilization
-
Gandour, R. D. and Schowen, R. L., Eds., Plenum, New York
-
Schowen, R. L., Catalytic power and transition-state stabilization, In Transition States of Biochemical Processes, Gandour, R. D. and Schowen, R. L., Eds., Plenum, New York, pp. 77-114, 1978.
-
(1978)
Transition States of Biochemical Processes
, pp. 77-114
-
-
Schowen, R.L.1
-
4
-
-
0028918401
-
A proficient enzyme
-
Radzicka, A. and Wolfenden, R., A proficient enzyme, Science, 267, 90-93, 1995.
-
(1995)
Science
, vol.267
, pp. 90-93
-
-
Radzicka, A.1
Wolfenden, R.2
-
5
-
-
0035543093
-
The depth of chemical time and the power of enzymes as catalysts
-
Wolfenden, R. and Snider, M. J., The depth of chemical time and the power of enzymes as catalysts, Acc. Chem. Res., 34, 938-945, 2001.
-
(2001)
Acc. Chem. Res.
, vol.34
, pp. 938-945
-
-
Wolfenden, R.1
Snider, M.J.2
-
6
-
-
0035997393
-
Catalytic proficiency: The unusual case of OMP decarboxylase
-
Miller, B. G. and Wolfenden, R., Catalytic proficiency: the unusual case of OMP decarboxylase, Annu. Rev. Biochem., 71, 847-885, 2002.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 847-885
-
-
Miller, B.G.1
Wolfenden, R.2
-
8
-
-
85056382893
-
-
Lewis, G. N. and Randall, M., Eds., McGraw-Hill, New York, Revision of, chap. 20
-
Pitzer, K. S. and Brewer, L., Thermodynamics, Lewis, G. N. and Randall, M., Eds., McGraw-Hill, New York, Revision of, chap. 20, p. 242, 1961.
-
(1961)
Thermodynamics
, pp. 242
-
-
Pitzer, K.S.1
Brewer, L.2
-
9
-
-
0016624901
-
Binding energy, specificity, and enzymic catalysis: The Circe effect
-
Jencks, W. P., Binding energy, specificity, and enzymic catalysis: the Circe effect, Adv. Enzymol. Relat. Areas Mol. Biol., 43, 219-410, 1975.
-
(1975)
Adv. Enzymol. Relat. Areas Mol. Biol.
, vol.43
, pp. 219-410
-
-
Jencks, W.P.1
-
10
-
-
0003447443
-
-
McGraw-Hill, New York, 1953, Reprinted by New York:Dover Publications
-
Gurney, R. W., Ionic Processes in Solution, McGraw-Hill, New York, 1953, Reprinted by New York:Dover Publications, 1963.
-
(1963)
Ionic Processes in Solution
-
-
Gurney, R.W.1
-
12
-
-
0030462453
-
Energy considerations show that low barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds
-
Warshel, A. and Papazyan, A., Energy considerations show that low barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds, Proc. Natl Acad. Sci. U.S.A., 93, 13665-13670, 1996.
-
(1996)
Proc. Natl Acad. Sci. U.S.A.
, vol.93
, pp. 13665-13670
-
-
Warshel, A.1
Papazyan, A.2
-
14
-
-
0030817281
-
Large kinetic isotope effects in enzymatic proton transfer and the role of substrate oscillations
-
Antoniou, D. and Schwartz, S. D., Large kinetic isotope effects in enzymatic proton transfer and the role of substrate oscillations, Proc. Natl Acad. Sci. U.S.A., 94, 12360-12365, 1997.
-
(1997)
Proc. Natl Acad. Sci. U.S.A.
, vol.94
, pp. 12360-12365
-
-
Antoniou, D.1
Schwartz, S.D.2
-
15
-
-
0041821836
-
A perspective on enzyme catalysis
-
Benkovic, S. J. and Hammes-Schiffer, S., A perspective on enzyme catalysis, Science, 301, 1196-1202, 2003.
-
(2003)
Science
, vol.301
, pp. 1196-1202
-
-
Benkovic, S.J.1
Hammes-Schiffer, S.2
-
16
-
-
0036009145
-
A view at the millennium: The efficiency of enzymatic catalysis
-
Bruice, T. C., A view at the millennium: the efficiency of enzymatic catalysis, Acc. Chem. Res., 35, 139-148, 2002.
-
(2002)
Acc. Chem. Res.
, vol.35
, pp. 139-148
-
-
Bruice, T.C.1
-
17
-
-
0346726109
-
How enzymes work: Analysis by modern rate theory and computer simulations
-
Garcia-Viloca, M., Gao, J., Karplus, M., and Truhlar, D. G., How enzymes work: analysis by modern rate theory and computer simulations, Science, 303, 186-195, 2004.
-
(2004)
Science
, vol.303
, pp. 186-195
-
-
Garcia-Viloca, M.1
Gao, J.2
Karplus, M.3
Truhlar, D.G.4
-
18
-
-
0037947804
-
Gas-phase bifluoride ion. An ion cyclotron resonance determination of the hydrogen bond energy in FHF- from gas-phase fluoride transfer equilibrium measurements
-
Larson, J. W. and McMahon, T. B., Gas-phase bifluoride ion. An ion cyclotron resonance determination of the hydrogen bond energy in FHF- from gas-phase fluoride transfer equilibrium measurements, J. Am. Chem. Soc., 104, 5848-5849, 1982.
-
(1982)
J. Am. Chem. Soc.
, vol.104
, pp. 5848-5849
-
-
Larson, J.W.1
McMahon, T.B.2
-
19
-
-
77956715871
-
Hydrogen bonding and chemical reactivity
-
Hibbert, F. and Emsley, J., Hydrogen bonding and chemical reactivity, Adv. Phys. Org. Chem., 26, 255-379, 1990.
-
(1990)
Adv. Phys. Org. Chem.
, vol.26
, pp. 255-379
-
-
Hibbert, F.1
Emsley, J.2
-
21
-
-
0003059838
-
Solvent isotope effects
-
Caldin, E. and Gold, V., Eds., Chapman & Hall, London
-
Albery, W. J., Solvent isotope effects, In Proton-Transfer Reactions, Caldin, E. and Gold, V., Eds., Chapman & Hall, London, pp. 263-315, 1975.
-
(1975)
Proton-Transfer Reactions
, pp. 263-315
-
-
Albery, W.J.1
-
22
-
-
0141645550
-
Low-temperature NMR studies of the structure and dynamics of a novel series of acid-base complexes of HF with collidine exhibiting scalar couplings across hydrogen bonds
-
Shenderovich, I. G., Tolstoy, P. M., Golubev, N. S., Smirnov, S. N., Denisov, G. S., and Limbach, H. H., Low-temperature NMR studies of the structure and dynamics of a novel series of acid-base complexes of HF with collidine exhibiting scalar couplings across hydrogen bonds, J. Am. Chem. Soc., 125, 11710-11720, 2003.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 11710-11720
-
-
Shenderovich, I.G.1
Tolstoy, P.M.2
Golubev, N.S.3
Smirnov, S.N.4
Denisov, G.S.5
Limbach, H.H.6
-
23
-
-
0030723218
-
A low-barrier hydrogen bond in the catalytic triad of serine proteases? Theory versus experiment
-
Ash, E. L., Sudmeier, J. L., De Fabo, E. C., and Bachovchin, W. W., A low-barrier hydrogen bond in the catalytic triad of serine proteases? Theory versus experiment, Science, 278, 1128-1132, 1997.
-
(1997)
Science
, vol.278
, pp. 1128-1132
-
-
Ash, E.L.1
Sudmeier, J.L.2
De Fabo, E.C.3
Bachovchin, W.W.4
-
24
-
-
0028769661
-
Symmetries of hydrogen bonds in solution
-
Perrin, C. L., Symmetries of hydrogen bonds in solution, Science, 266, 1665-1668, 1994.
-
(1994)
Science
, vol.266
, pp. 1665-1668
-
-
Perrin, C.L.1
-
25
-
-
0030632978
-
“Strong” hydrogen bonds in chemistry and biology
-
Perrin, C. L. and Nielson, J. B., “Strong” hydrogen bonds in chemistry and biology, Annu. Rev. Phys. Chem., 48, 511-544, 1997.
-
(1997)
Annu. Rev. Phys. Chem.
, vol.48
, pp. 511-544
-
-
Perrin, C.L.1
Nielson, J.B.2
-
26
-
-
0032501454
-
Symmetry of the hydrogen bond in malonaldehyde enol in solution
-
Perrin, C. L. and Kim, Y. J., Symmetry of the hydrogen bond in malonaldehyde enol in solution, J. Am. Chem. Soc., 120, 12641-12645, 1998.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 12641-12645
-
-
Perrin, C.L.1
Kim, Y.J.2
-
28
-
-
0037233624
-
Symmetry of NHN hydrogen bonds in solution
-
Perrin, C. L. and Ohta, B. K., Symmetry of NHN hydrogen bonds in solution, J. Mol. Struct., 644, 1-12, 2003.
-
(2003)
J. Mol. Struct.
, vol.644
, pp. 1-12
-
-
Perrin, C.L.1
Ohta, B.K.2
-
29
-
-
0028693333
-
Ab initio studies of hydrogen bonds: The water dimer paradigm
-
Scheiner, S., Ab initio studies of hydrogen bonds: the water dimer paradigm, Annu. Rev. Phys. Chem., 45, 23-56, 1994.
-
(1994)
Annu. Rev. Phys. Chem.
, vol.45
, pp. 23-56
-
-
Scheiner, S.1
-
31
-
-
0037032252
-
Comparison of various types of hydrogen bonds involving aromatic amino acids
-
Scheiner, S., Kar, T., and Pattanayak, J., Comparison of various types of hydrogen bonds involving aromatic amino acids, J. Am. Chem. Soc., 124, 13257-13264, 2002.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 13257-13264
-
-
Scheiner, S.1
Kar, T.2
Pattanayak, J.3
-
32
-
-
0035936229
-
Influence of hybridization and substitution on the properties of the C H • • • O hydrogen bond
-
Scheiner, S., Grabowski, S. J., and Kar, T., Influence of hybridization and substitution on the properties of the C H • • • O hydrogen bond, J. Phys. Chem. A, 105, 10607-10612, 2001.
-
(2001)
J. Phys. Chem. A
, vol.105
, pp. 10607-10612
-
-
Scheiner, S.1
Grabowski, S.J.2
Kar, T.3
-
33
-
-
0038758705
-
F-N) across F-H • • • N hydrogen bonds
-
F-N) across F-H • • • N hydrogen bonds, J. Phys. Chem. A, 107, 3121-3125, 2003.
-
(2003)
J. Phys. Chem. A
, vol.107
, pp. 3121-3125
-
-
Del Bene, J.E.1
Perera, S.A.2
Bartlett, R.J.3
Yanez, M.4
Mo, O.5
Elguero, J.6
Alkorta, I.7
-
34
-
-
0038341750
-
+• • • F hydrogen bonds
-
+• • • F hydrogen bonds, J. Phys. Chem. A, 107, 3126-3131, 2003.
-
(2003)
J. Phys. Chem. A
, vol.107
, pp. 3126-3131
-
-
Del Bene, J.E.1
Perera, S.A.2
Bartlett, R.J.3
Yanez, M.4
Mo, O.5
Elguero, J.6
Alkorta, I.7
-
35
-
-
0037996657
-
C-N) across C-H -N hydrogen bonds
-
C-N) across C-H -N hydrogen bonds, J. Phys. Chem. A, 107, 3222-3227, 2003.
-
(2003)
J. Phys. Chem. A
, vol.107
, pp. 3222-3227
-
-
Del Bene, J.E.1
Perera, S.A.2
Bartlett, R.J.3
Yanez, M.4
Mo, O.5
Elguero, J.6
Alkorta, I.7
-
36
-
-
0000010849
-
Theoretical investigation of the relationship between proton NMR chemical shift and hydrogen bond strength
-
Kumar, G. A. and McAllister, M. A., Theoretical investigation of the relationship between proton NMR chemical shift and hydrogen bond strength, J. Org. Chem., 63, 6968-6972, 1998.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 6968-6972
-
-
Kumar, G.A.1
McAllister, M.A.2
-
37
-
-
0000995427
-
Short strong hydrogen bonds in the gas phase and solution: Theoretical exploration of pKa matching and environmental effects on the strengths of hydrogen bonds and their potential roles in enzymatic catalysis
-
Chen, J., McAllister, M. A., Lee, J. K., and Houk, K. N. Short, strong hydrogen bonds in the gas phase and solution: Theoretical exploration of pKa matching and environmental effects on the strengths of hydrogen bonds and their potential roles in enzymatic catalysis, J. Org. Chem., 63, 4611-4619, 1998.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 4611-4619
-
-
Chen, J.1
McAllister, M.A.2
Lee, J.K.3
Houk, K.N.4
-
38
-
-
0032583486
-
Enthalpic studies of complex formation between carboxylic acids and 1-alkylimidazoles
-
Reinhardt, L. A., Sacksteder, K. A., and Cleland, W. W., Enthalpic studies of complex formation between carboxylic acids and 1-alkylimidazoles, J. Am. Chem. Soc., 120, 13366-13369, 1998.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 13366-13369
-
-
Reinhardt, L.A.1
Sacksteder, K.A.2
Cleland, W.W.3
-
39
-
-
0029926948
-
The energetics of hydrogen bonds in model systems:Implications for enzymatic catalysis
-
Shan, S. O., Loh, S., and Herschlag, D., The energetics of hydrogen bonds in model systems:implications for enzymatic catalysis, Science, 272, 97-101, 1996.
-
(1996)
Science
, vol.272
, pp. 97-101
-
-
Shan, S.O.1
Loh, S.2
Herschlag, D.3
-
40
-
-
0029905014
-
The change in hydrogen bond strength accompanying charge rearrangement:Implications for enzymatic catalysis
-
Shan, S.O. and Herschlag, D., The change in hydrogen bond strength accompanying charge rearrangement:implications for enzymatic catalysis, Proc. Natl Acad. Sci. USA, 93, 14474-14479, 1996.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 14474-14479
-
-
Shan, S.O.1
Herschlag, D.2
-
41
-
-
0032963717
-
Proton relay system in the active site of maltodextrinphosphorylase via hydrogen bonds with large proton polarizability: An FT-IR difference spectroscopy study
-
Bartl, F., Palm, D., Schinzel, R., and Zundel, G., Proton relay system in the active site of maltodextrinphosphorylase via hydrogen bonds with large proton polarizability: an FT-IR difference spectroscopy study, Eur. Biophys. J., 28, 200-207, 1999.
-
(1999)
Eur. Biophys. J.
, vol.28
, pp. 200-207
-
-
Bartl, F.1
Palm, D.2
Schinzel, R.3
Zundel, G.4
-
42
-
-
0037146045
-
Molecular structure of the solvated proton in isolated salts. Short, strong, low barrier (SSLB) H-bonds
-
Stasko, D., Hoffmann, S. P., Kim, K. C., Fackler, N. L., Larsen, A. S., Drovetskaya, T., Tham, F. S., Reed, C. A., Rickard, C. E., Boyd, P. D., and Stoyanov, E. S., Molecular structure of the solvated proton in isolated salts. Short, strong, low barrier (SSLB) H-bonds, J. Am. Chem. Soc., 124, 13869-13876, 2002.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 13869-13876
-
-
Stasko, D.1
Hoffmann, S.P.2
Kim, K.C.3
Fackler, N.L.4
Larsen, A.S.5
Drovetskaya, T.6
Tham, F.S.7
Reed, C.A.8
Rickard, C.E.9
Boyd, P.D.10
Stoyanov, E.S.11
-
43
-
-
0036260620
-
Understanding protein hydrogen bond formation with kinetic H/D amide isotope effects
-
Krantz, B. A., Srivastava, A. K., Nauli, S., Baker, D., Sauer, R. T., and Sosnick, T. R., Understanding protein hydrogen bond formation with kinetic H/D amide isotope effects, Nat. Struct. Biol., 9, 458-463, 2002.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 458-463
-
-
Krantz, B.A.1
Srivastava, A.K.2
Nauli, S.3
Baker, D.4
Sauer, R.T.5
Sosnick, T.R.6
-
44
-
-
0027982960
-
Hydrogen bonding in proteins as studied by amide hydrogen H/D fractionation factors: Application to staphylococcal nuclease
-
Loh, S. N. and Markley, J. L., Hydrogen bonding in proteins as studied by amide hydrogen H/D fractionation factors: application to staphylococcal nuclease, Biochemistry, 33, 1029-1036, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 1029-1036
-
-
Loh, S.N.1
Markley, J.L.2
-
45
-
-
0030469181
-
15N labeled human ubiquitin by triple resonance NMR
-
15N labeled human ubiquitin by triple resonance NMR, J. Am. Chem. Soc., 118, 12864-12865, 1996.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 12864-12865
-
-
LiWang, A.C.1
Bax, A.2
-
46
-
-
0029882296
-
Hydrogen bonding and equilibrium isotope enrichment in histidinecontaining proteins
-
Bowers, P. M. and Klevit, R. E., Hydrogen bonding and equilibrium isotope enrichment in histidinecontaining proteins, Nat. Struct. Biol., 3, 522-531, 1996.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 522-531
-
-
Bowers, P.M.1
Klevit, R.E.2
-
47
-
-
0028888735
-
Theoretical studies of protium or deuterium fractionation factors and cooperative hydrogen bonding in peptides
-
Edison, A. S., Weinhold, F., and Markley, J. L., Theoretical studies of protium or deuterium fractionation factors and cooperative hydrogen bonding in peptides, J. Am. Chem. Soc., 117, 9619-9624, 1995.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 9619-9624
-
-
Edison, A.S.1
Weinhold, F.2
Markley, J.L.3
-
48
-
-
0000654579
-
Effect of structural changes in reactants on the position of hydrogen-bonding hydrogens and solvating molecules in transition states. The mechanism of tetrahydrofuran formation from 4-chlorobutanol
-
Swain, C. G., Kuhn, D. A., and Schowen, R. L., Effect of structural changes in reactants on the position of hydrogen-bonding hydrogens and solvating molecules in transition states. The mechanism of tetrahydrofuran formation from 4-chlorobutanol, J. Am. Chem. Soc., 87, 1553-1561, 1965.
-
(1965)
J. Am. Chem. Soc.
, vol.87
, pp. 1553-1561
-
-
Swain, C.G.1
Kuhn, D.A.2
Schowen, R.L.3
-
49
-
-
84982238151
-
Mechanism and catalysis for the hydrolysis of acetals, ketals, and ortho esters
-
Cordes, E. H., Mechanism and catalysis for the hydrolysis of acetals, ketals, and ortho esters, Prog. Phys. Org. Chem., 4, 1-44, 1967.
-
(1967)
Prog. Phys. Org. Chem.
, vol.4
, pp. 1-44
-
-
Cordes, E.H.1
-
50
-
-
0000713188
-
Kinetic hydrogen isotope effects in the concerted mechanism for the hydrolysis of acetals, ketals, and ortho esters
-
Eliason, R. and Kreevoy, M. M., Kinetic hydrogen isotope effects in the concerted mechanism for the hydrolysis of acetals, ketals, and ortho esters, J. Am. Chem. Soc., 100, 7037-7041, 1978.
-
(1978)
J. Am. Chem. Soc.
, vol.100
, pp. 7037-7041
-
-
Eliason, R.1
Kreevoy, M.M.2
-
51
-
-
0037172784
-
Contributions of active site residues to the partial and overall catalytic activities of human S-adenosylhomocysteine hydrolase
-
Elrod, P., Zhang, J., Yang, X., Yin, D., Hu, Y., Borchardt, R. T., and Schowen, R. L., Contributions of active site residues to the partial and overall catalytic activities of human S-adenosylhomocysteine hydrolase, Biochemistry., 41, 8134-8142, 2002.
-
(2002)
Biochemistry.
, vol.41
, pp. 8134-8142
-
-
Elrod, P.1
Zhang, J.2
Yang, X.3
Yin, D.4
Hu, Y.5
Borchardt, R.T.6
Schowen, R.L.7
-
52
-
-
0036882394
-
Serine protease mechanism and specificity
-
Hedstrom, L., Serine protease mechanism and specificity, Chem. Rev., 102, 4501-4523, 2002.
-
(2002)
Chem. Rev.
, vol.102
, pp. 4501-4523
-
-
Hedstrom, L.1
-
53
-
-
0015506470
-
High resolution nuclear magnetic resonance study of hte histidine-aspartate hydrogen bond in chymotrypsin and chymotrypsinogen
-
Robillard, G. and Shulman, R.G., High resolution nuclear magnetic resonance study of hte histidine-aspartate hydrogen bond in chymotrypsin and chymotrypsinogen, J. Mol. Biol., 71, 507-511, 1972.
-
(1972)
J. Mol. Biol.
, vol.71
, pp. 507-511
-
-
Robillard, G.1
Shulman, R.G.2
-
54
-
-
0023204278
-
The catalytic role of the active site aspartic acid in serine proteases
-
Craik, C. S., Roczniak, S., Largman, C., and Rutter, W. J., The catalytic role of the active site aspartic acid in serine proteases, Science, 237, 909-913, 1987.
-
(1987)
Science
, vol.237
, pp. 909-913
-
-
Craik, C.S.1
Roczniak, S.2
Largman, C.3
Rutter, W.J.4
-
55
-
-
0023161184
-
The three-dimensional structure of Asn102 mutant of trypsin: Role of Asp102 in serine protease catalysis
-
Sprang, S., Standing, T., Fletterick, R. J., Stroud, R. M., Finer-Moore, J., Xuong, N. H., Hamlin, R., Rutter, W. J., and Craik, C. S., The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis, Science, 237, 905-909, 1987.
-
(1987)
Science
, vol.237
, pp. 905-909
-
-
Sprang, S.1
Standing, T.2
Fletterick, R.J.3
Stroud, R.M.4
Finer-Moore, J.5
Xuong, N.H.6
Hamlin, R.7
Rutter, W.J.8
Craik, C.S.9
-
56
-
-
0034640453
-
Hydrogen bonds and proton transfer in general-catalytic transition-state stabilization in enzyme catalysis
-
Schowen, K. B., Limbach, H. H., Denisov, G. S., and Schowen, R. L., Hydrogen bonds and proton transfer in general-catalytic transition-state stabilization in enzyme catalysis, Biochim. Biophys. Acta, 1458, 43-62, 2000.
-
(2000)
Biochim. Biophys. Acta
, vol.1458
, pp. 43-62
-
-
Schowen, K.B.1
Limbach, H.H.2
Denisov, G.S.3
Schowen, R.L.4
-
57
-
-
0021118947
-
The proton inventory technique
-
Venkatasubban, K. S. and Schowen, R. L., The proton inventory technique, CRC Crit. Rev. Biochem., 17, 1-44, 1984.
-
(1984)
CRC Crit. Rev. Biochem.
, vol.17
, pp. 1-44
-
-
Venkatasubban, K.S.1
Schowen, R.L.2
-
58
-
-
0040344445
-
Structural and energetic aspects of protolytic catalysis by enzymes: Charge-relay catalysis in the function of serine proteases
-
Liebman, J. F. and Greenberg, A., Eds., VCH, New York
-
Schowen, R. L., Structural and energetic aspects of protolytic catalysis by enzymes: charge-relay catalysis in the function of serine proteases, In Molecular Structure and Energetics, Liebman, J. F. and Greenberg, A., Eds., VCH, New York, pp. 119-168, 1988.
-
(1988)
Molecular Structure and Energetics
, pp. 119-168
-
-
Schowen, R.L.1
-
59
-
-
0039824830
-
The contribution of secondary proton bridges to the catalytic power of the serine proteases
-
Bibbs, J.A., Garoutte, M. P., Wang, B., Tittel, P. D., Schowen, K. B., and Schowen, R. L., The contribution of secondary proton bridges to the catalytic power of the serine proteases, Ber Bunsenges Phys. Chem., 102, 573-579, 1997.
-
(1997)
Ber Bunsenges Phys. Chem.
, vol.102
, pp. 573-579
-
-
Bibbs, J.A.1
Garoutte, M.P.2
Wang, B.3
Tittel, P.D.4
Schowen, K.B.5
Schowen, R.L.6
-
60
-
-
0008053511
-
P1 residue determines the operation of the catalytic triad of serine proteases during hydrolyses of acyl enzymes
-
Sten, R. L. and Strimpler, A. M., P1 residue determines the operation of the catalytic triad of serine proteases during hydrolyses of acyl enzymes, J. Am. Chem. Soc., 109, 4387-4390, 1987.
-
(1987)
J. Am. Chem. Soc.
, vol.109
, pp. 4387-4390
-
-
Sten, R.L.1
Strimpler, A.M.2
-
61
-
-
85056421000
-
-
Williams, A. and Page, M. I., Eds., R.S.C., London, chap. 10
-
Fink, A. L., Enzyme Mechanisms, Williams, A. and Page, M. I., Eds., R.S.C., London, 1987, chap. 10.
-
(1987)
Enzyme Mechanisms
-
-
Fink, A.L.1
-
62
-
-
0035957102
-
Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin
-
Neidhart, D., Wei, Y., Cassidy, C., Lin, J., Cleland, W. W., and Frey, P. A., Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin, Biochemistry, 40, 2439-2447, 2001.
-
(2001)
Biochemistry
, vol.40
, pp. 2439-2447
-
-
Neidhart, D.1
Wei, Y.2
Cassidy, C.3
Lin, J.4
Cleland, W.W.5
Frey, P.A.6
-
63
-
-
0037165710
-
Evidence for a strong hydrogen bond in the catalytic dyad of transition-state analogue inhibitor complexes of chymotrypsin from proton-triton NMR isotope shifts
-
Westler, W. M., Frey, P. A., Lin, J., Wemmer, D. E., Morimoto, H., Williams, P. G., and Markley, J. L., Evidence for a strong hydrogen bond in the catalytic dyad of transition-state analogue inhibitor complexes of chymotrypsin from proton-triton NMR isotope shifts, J. Am. Chem. Soc., 124, 4196-4197, 2002.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 4196-4197
-
-
Westler, W.M.1
Frey, P.A.2
Lin, J.3
Wemmer, D.E.4
Morimoto, H.5
Williams, P.G.6
Markley, J.L.7
-
64
-
-
0032475836
-
The low barrier hydrogen bond in enzymatic catalysis
-
Cleland, W. W., Frey, P. A., and Gerlt, J. A., The low barrier hydrogen bond in enzymatic catalysis, J. Biol. Chem., 273, 25529-25532, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25529-25532
-
-
Cleland, W.W.1
Frey, P.A.2
Gerlt, J.A.3
-
65
-
-
0029040169
-
On low barrier hydrogen bonds and enzyme catalysis
-
Warshel, A., Papazyan, A., and Kollman, P. A., On low barrier hydrogen bonds and enzyme catalysis, Science, 269, 102-106, 1995.
-
(1995)
Science
, vol.269
, pp. 102-106
-
-
Warshel, A.1
Papazyan, A.2
Kollman, P.A.3
-
66
-
-
0031275493
-
Is an extremely low-field proton signal in the NMR spectrum conclusive evidence for a low-barrier hydrogen bond?
-
Garcia-Viloca, M., Gelabert, R., González-Lafont, A., Moreno, M., and Lluch, J. M., Is an extremely low-field proton signal in the NMR spectrum conclusive evidence for a low-barrier hydrogen bond?, J. Phys. Chem. A, 101, 8727-8733, 1997.
-
(1997)
J. Phys. Chem. A
, vol.101
, pp. 8727-8733
-
-
Garcia-Viloca, M.1
Gelabert, R.2
González-Lafont, A.3
Moreno, M.4
Lluch, J.M.5
-
68
-
-
0036285978
-
Molecular dynamics simulations of biological reactions
-
Warshel, A., Molecular dynamics simulations of biological reactions, Acc. Chem. Res., 35, 385-395, 2002.
-
(2002)
Acc. Chem. Res.
, vol.35
, pp. 385-395
-
-
Warshel, A.1
-
69
-
-
0041876227
-
Computer simulations of enzyme catalysis: Methods, progress, and insights
-
Warshel, A., Computer simulations of enzyme catalysis: methods, progress, and insights, Annu. Rev. Biophys. Biomol. Struct., 32, 425-443, 2003.
-
(2003)
Annu. Rev. Biophys. Biomol. Struct.
, vol.32
, pp. 425-443
-
-
Warshel, A.1
-
70
-
-
0028854341
-
The nonexistence of specially stabilized hydrogen bonds in enzymes
-
Scheiner, S. and Kar, T., The nonexistence of specially stabilized hydrogen bonds in enzymes, J. Am. Chem. Soc., 117, 6970-6975, 1995.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 6970-6975
-
-
Scheiner, S.1
Kar, T.2
-
71
-
-
84962477148
-
Structure or function correlations of proteins using MM, QM/MM, and related approaches: Methods, concepts, pitfalls, and current progress
-
Shurki, A. and Warshel, A., Structure or function correlations of proteins using MM, QM/MM, and related approaches: methods, concepts, pitfalls, and current progress, Adv. Protein Chem., 66, 249-313, 2003.
-
(2003)
Adv. Protein Chem.
, vol.66
, pp. 249-313
-
-
Shurki, A.1
Warshel, A.2
-
72
-
-
0034716340
-
Ab initio QM/MM study of the citrate synthase mechanism. A low-barrier hydrogen bond is not involved
-
Mulholland, A. J., Lyne, P. D., and Karplus, M., Ab initio QM/MM study of the citrate synthase mechanism. A low-barrier hydrogen bond is not involved, J. Am. Chem. Soc., 122, 534-535, 2000.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 534-535
-
-
Mulholland, A.J.1
Lyne, P.D.2
Karplus, M.3
-
73
-
-
0035807053
-
A novel engineered subtilisin BPN’ lacking a low-barrier hydrogen bond in the catalytic triad
-
Stratton, J. R., Pelton, J. G., and Kirsch, J. F., A novel engineered subtilisin BPN’ lacking a low-barrier hydrogen bond in the catalytic triad, Biochemistry, 40, 10411-10416, 2001.
-
(2001)
Biochemistry
, vol.40
, pp. 10411-10416
-
-
Stratton, J.R.1
Pelton, J.G.2
Kirsch, J.F.3
-
74
-
-
0026885447
-
Oxyanion hole interactions in serine and cysteine proteases
-
Menard, R. and Storer, A. C., Oxyanion hole interactions in serine and cysteine proteases, Biol. Chem. Hoppe Seyler, 373, 393-400, 1992.
-
(1992)
Biol. Chem. Hoppe Seyler
, vol.373
, pp. 393-400
-
-
Menard, R.1
Storer, A.C.2
-
75
-
-
2142766704
-
Methyl chymotrypsin catalyzed hydrolysis of specific substrate esters indicate multiple proton catalysis is possible with a modified charge relay triad
-
Scholten, J. D., Hogg, J. L., and Raushel, F. M., Methyl chymotrypsin catalyzed hydrolysis of specific substrate esters indicate multiple proton catalysis is possible with a modified charge relay triad, J. Am. Chem. Soc., 110, 8246-8247, 1988.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 8246-8247
-
-
Scholten, J.D.1
Hogg, J.L.2
Raushel, F.M.3
-
76
-
-
0029789988
-
2O mixtures (proton inventories) on serine-protease-catalyzed hydrolysis reactions. Influence of oxyanion hole interactions and medium effects
-
2O mixtures (proton inventories) on serine-protease-catalyzed hydrolysis reactions. Influence of oxyanion hole interactions and medium effects, J. Am. Chem. Soc., 118, 8802-9907, 1996.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 8802-9907
-
-
Chang, T.K.1
Chiang, Y.2
Guo, H.X.3
Kresge, A.J.4
Mathew, L.5
Powell, M.F.6
Wells, J.A.7
-
77
-
-
0037019547
-
Role of the catalytic triad and oxyanion hole in acetylcholinesterase catalysis: An ab initio QM/MM study
-
Zhang, Y., Kua, J., and McCammon, J. A., Role of the catalytic triad and oxyanion hole in acetylcholinesterase catalysis: an ab initio QM/MM study, J. Am. Chem. Soc., 124, 10572-10577, 2002.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 10572-10577
-
-
Zhang, Y.1
Kua, J.2
McCammon, J.A.3
-
78
-
-
0345316119
-
Catalysis by human leukocyte elastase. 5. Structural features of the virtual transition state for acylation
-
Stein, R. L., Catalysis by human leukocyte elastase. 5. Structural features of the virtual transition state for acylation, J. Am. Chem. Soc., 107, 7768-7769, 1985.
-
(1985)
J. Am. Chem. Soc.
, vol.107
, pp. 7768-7769
-
-
Stein, R.L.1
-
79
-
-
0032845707
-
Energetics of substrate binding, catalysis, and product release
-
Cleland, W. W. and Northrop, D. B., Energetics of substrate binding, catalysis, and product release, Methods Enzymol., 308(part E), 3-27, 1999.
-
(1999)
Methods Enzymol.
, vol.308
, pp. 3-27
-
-
Cleland, W.W.1
Northrop, D.B.2
|