Energy considerations show that low-barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 24, 1996, Pages 13665-13670

  Warshel, Arieh ^a   Papazyan, Arno ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

electrostatics; enzymes; evolution; subtilisin; transition state

Indexed keywords

CHEMICAL REACTION KINETICS; CONFERENCE PAPER; ENERGY METABOLISM; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STABILITY; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL;

EID: 0030462453     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.24.13665     Document Type: Article

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