-
1
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. (2010) 363:711-23. doi:10.1056/NEJMoa1003466.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
2
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C, Long GV, Brady B, Dutriaux C, Maio M, Mortier L, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. (2015) 372:320-30. doi:10.1056/NEJMoa1412082.
-
(2015)
N Engl J Med
, vol.372
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
Dutriaux, C.4
Maio, M.5
Mortier, L.6
-
3
-
-
85040860527
-
Development of PD-1 AND PD-L1 inhibitors as a form of cancer immunotherapy: A comprehensive review of registration trials and future considerations
-
Gong J, Chehrazi-Raffle A, Reddi S, Salgia R. Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: A comprehensive review of registration trials and future considerations. J Immunother Cancer (2018) 6:8. doi:10.1186/s40425-018-0316-z.
-
(2018)
J Immunother Cancer
, vol.6
, pp. 8
-
-
Gong, J.1
Chehrazi-Raffle, A.2
Reddi, S.3
Salgia, R.4
-
4
-
-
84941280057
-
Beyond CTLA-4 AND PD-1, the generation z of negative checkpoint regulators
-
Le Mercier I, Lines JL, Noelle RJ. Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators. Front Immunol. (2015) 6:418. doi:10.3389/fimmu.2015.00418.
-
(2015)
Front Immunol
, vol.6
, pp. 418
-
-
Le, M.I.1
Lines, J.L.2
Noelle, R.J.3
-
5
-
-
84953309212
-
Immune-related adverse events with immune checkpoint blockade: A comprehensive review
-
Michot JM, Bigenwald C, Champiat S, Collins M, Carbonnel F, Postel-Vinay S, et al. Immune-related adverse events with immune checkpoint blockade: A comprehensive review. Eur J Cancer (2016) 54:139-48. doi:10.1016/j.ejca.2015.11.016.
-
(2016)
Eur J Cancer
, vol.54
, pp. 139-148
-
-
Michot, J.M.1
Bigenwald, C.2
Champiat, S.3
Collins, M.4
Carbonnel, F.5
Postel-Vinay, S.6
-
6
-
-
0028867420
-
Loss of ctla-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of ctla-4=
-
Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH.Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity (1995) 3:541-7. doi:10.1016/1074-7613(95)90125-6.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
7
-
-
84907909000
-
Immune dysregulation in human subjects with heterozygous germline mutations in ctla4
-
Kuehn HS, Ouyang W, Lo B, Deenick EK, Niemela JE, Avery DT, et al. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. Science (2014) 345:1623-7. doi:10.1126/science.1255904.
-
(2014)
Science
, vol.345
, pp. 1623-1627
-
-
Kuehn, H.S.1
Ouyang, W.2
Lo, B.3
Deenick, E.K.4
Niemela, J.E.5
Avery, D.T.6
-
8
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in Pd-1 receptor-deficient mice
-
Nishimura H, Okazaki T, Tanaka Y, Nakatani K, Hara M, Matsumori A, et al. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science (2001) 291:319-22. doi:10.1126/science.291.5502.319.
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
Nakatani, K.4
Hara, M.5
Matsumori, A.6
-
9
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the pd-1 gene encoding an itim motif-carrying immunoreceptor
-
Nishimura H, Nose M, Hiai H, Minato N, and Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity (1999) 11:141-51. doi:10.1016/S1074-7613(00)80089-8.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
10
-
-
13244277850
-
A regulatory polymorphism in pdcd1 is associated with susceptibility to systemic lupus erythematosus in humans
-
Prokunina L, Castillejo-López C, Oberg F, Gunnarsson I, Berg L, Magnusson V, et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet. (2002) 32:666-9. doi:10.1038/ng1020.
-
(2002)
Nat Genet
, vol.32
, pp. 666-669
-
-
Prokunina, L.1
Castillejo-López, C.2
Oberg, F.3
Gunnarsson, I.4
Berg, L.5
Magnusson, V.6
-
11
-
-
30744431930
-
Pdcd1: A tissue-specific susceptibility locus for inherited inflammatory disorders
-
James ES, Harney S, Wordsworth BP, Cookson WO, Davis SJ, Moffatt MF. PDCD1: A tissue-specific susceptibility locus for inherited inflammatory disorders. Genes Immun. (2005) 6:430-7. doi:10.1038/sj.gene.6364223.
-
(2005)
Genes Immun
, vol.6
, pp. 430-437
-
-
James, E.S.1
Harney, S.2
Wordsworth, B.P.3
Cookson, W.O.4
Davis, S.J.5
Moffatt, M.F.6
-
12
-
-
84939892080
-
Meta-Analysis of genetic polymorphisms in programmed cell death 1. Associations with rheumatoid arthritis, ankylosing spondylitis, and type 1 diabetes susceptibility
-
Lee YH, Bae SC, Kim JH, Song GG. Meta-Analysis of genetic polymorphisms in programmed cell death 1. Associations with rheumatoid arthritis, ankylosing spondylitis, and type 1 diabetes susceptibility. Z Rheumatol. (2015) 74:230-9. doi:10.1007/s00393-014-1415-y.
-
(2015)
Z Rheumatol
, vol.74
, pp. 230-239
-
-
Lee, Y.H.1
Bae, S.C.2
Kim, J.H.3
Song, G.G.4
-
13
-
-
21844451620
-
A pd-1 polymorphism is associated with disease progression in multiple sclerosis
-
Kroner A, Mehling M, Hemmer B, Rieckmann P, Toyka KV, Mäurer M, et al. A PD-1 polymorphism is associated with disease progression in multiple sclerosis. Ann Neurol. (2005) 58:50-7. doi:10.1002/ana.20514.
-
(2005)
Ann Neurol
, vol.58
, pp. 50-57
-
-
Kroner, A.1
Mehling, M.2
Hemmer, B.3
Rieckmann, P.4
Toyka, K.V.5
Mäurer, M.6
-
14
-
-
4444355857
-
Interferon-beta enhances monocyte and dendritic cell expression of b7-h1 (pd-l1), a strong inhibitor of autologous T-cell activation: Relevance for the immune modulatory effect in multiple sclerosis
-
Schreiner B, Mitsdoerffer M, Kieseier BC, Chen L, Hartung HP, Weller M, et al. Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: Relevance for the immune modulatory effect in multiple sclerosis. J Neuroimmunol. (2004) 155:172-82. doi:10.1016/j.jneuroim.2004.06.013.
-
(2004)
J Neuroimmunol.
, vol.155
, pp. 172-182
-
-
Schreiner, B.1
Mitsdoerffer, M.2
Kieseier, B.C.3
Chen, L.4
Hartung, H.P.5
Weller, M.6
-
15
-
-
0037312070
-
Costimulating aberrant t cell responses by b7-h1 autoantibodies in rheumatoid arthritis
-
Dong H, Strome SE, Matteson EL, Moder KG, Flies DB, Zhu G, et al. Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis. J Clin Invest. (2003) 111:363-70. doi:10.1172/JCI16015.
-
(2003)
J Clin Invest
, vol.111
, pp. 363-370
-
-
Dong, H.1
Strome, S.E.2
Matteson, E.L.3
Moder, K.G.4
Flies, D.B.5
Zhu, G.6
-
16
-
-
49449113696
-
Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking b and t lymphocyte attenuator
-
Oya Y, Watanabe N, Owada T, Oki M, Hirose K, Suto A, et al. Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator. Arthritis Rheum. (2008) 58:2498-510. doi:10.1002/art.23674.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2498-2510
-
-
Oya, Y.1
Watanabe, N.2
Owada, T.3
Oki, M.4
Hirose, K.5
Suto, A.6
-
17
-
-
79955123802
-
A functional polymorphism in b and t lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis
-
Oki M, Watanabe N, Owada T, Oya Y, Ikeda K, Saito Y, et al. A functional polymorphism in B and T lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis. Clin Dev Immunol. (2011) 2011:305656. doi:10.1155/2011/305656.
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 305656
-
-
Oki, M.1
Watanabe, N.2
Owada, T.3
Oya, Y.4
Ikeda, K.5
Saito, Y.6
-
18
-
-
79251572651
-
Cutting edge: TIGIT has t cell-intrinsic inhibitory functions
-
Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, et al. Cutting edge: TIGIT has T cell-intrinsic inhibitory functions. J Immunol. (2011) 186:1338-42. doi:10.4049/jimmunol.1003081.
-
(2011)
J Immunol
, vol.186
, pp. 1338-1342
-
-
Joller, N.1
Hafler, J.P.2
Brynedal, B.3
Kassam, N.4
Spoerl, S.5
Levin, S.D.6
-
19
-
-
84969900682
-
Tim-3 rs10515746 (a/c) and rs10053538 (C/A) gene polymorphisms and risk of multiple sclerosis
-
Yaghoobi E, Abedian S, Babani O, Izad M. TIM-3 Rs10515746 (A/C) and Rs10053538 (C/A) Gene polymorphisms and risk of multiple sclerosis. Iran J Public Health (2016) 45:644-49.
-
(2016)
Iran J Public Health
, vol.45
, pp. 644-649
-
-
Yaghoobi, E.1
Abedian, S.2
Babani, O.3
Izad, M.4
-
20
-
-
4344626175
-
The polymorphisms of TH1 cell surface gene TIM-3 are associated in a Korean population with rheumatoid arthritis
-
Chae SC, Park YR, Shim SC, Yoon KS, Chung HT. The polymorphisms of Th1 cell surface gene Tim-3 are associated in a Korean population with rheumatoid arthritis. Immunol Lett. (2004) 95:91-5. doi:10.1016/j.imlet.2004.06.008.
-
(2004)
Immunol Lett
, vol.95
, pp. 91-95
-
-
Chae, S.C.1
Park, Y.R.2
Shim, S.C.3
Yoon, K.S.4
Chung, H.T.5
-
21
-
-
84907567539
-
Tim-3 polymorphism down regulates gene expression and is involved in the susceptibility to ankylosing spondylitis
-
Wang M, Ji B, Wang J, Cheng X, Zhou Q, Zhou J, et al. Tim-3 polymorphism downregulates gene expression and is involved in the susceptibility to ankylosing spondylitis. DNA Cell Biol. (2014) 33:723-8. doi:10.1089/dna.2014.2456.
-
(2014)
DNA Cell Biol
, vol.33
, pp. 723-728
-
-
Wang, M.1
Ji, B.2
Wang, J.3
Cheng, X.4
Zhou, Q.5
Zhou, J.6
-
22
-
-
77954220941
-
The programmed death 1/programmed death ligand 1 inhibitory pathway is up-regulated in rheumatoid synovium and regulates peripheral t cell responses in human and murine arthritis
-
Raptopoulou AP, Bertsias G, Makrygiannakis D, Verginis P, Kritikos I, Tzardi M, et al. The programmed death 1/programmed death ligand 1 inhibitory pathway is up-regulated in rheumatoid synovium and regulates peripheral T cell responses in human and murine arthritis. Arthritis Rheum. (2010). 62:1870-80. doi:10.1002/art.27500.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1870-1880
-
-
Raptopoulou, A.P.1
Bertsias, G.2
Makrygiannakis, D.3
Verginis, P.4
Kritikos, I.5
Tzardi, M.6
-
23
-
-
79954451635
-
The effects of PDL-IG on collagen-induced arthritis
-
Wang G, Hu P, Yang J, Shen G, Wu X. The effects of PDL-Ig on collagen-induced arthritis. Rheumatol Int. (2011) 31:513-9. doi:10.1007/s00296-009-1249-0.
-
(2011)
Rheumatol, Int
, vol.31
, pp. 513-519
-
-
Wang, G.1
Hu, P.2
Yang, J.3
Shen, G.4
Wu, X.5
-
24
-
-
84920873268
-
Protective effects of FC-fused pd-l1 on two different animal models of colitis
-
Song MY, Hong CP, Park SJ, Kim JH, Yang BG, Park Y, et al. Protective effects of Fc-fused PD-L1 on two different animal models of colitis. Gut (2015) 64:260-71. doi:10.1136/gutjnl-2014-307311.
-
(2015)
Gut
, vol.64
, pp. 260-271
-
-
Song, M.Y.1
Hong, C.P.2
Park, S.J.3
Kim, J.H.4
Yang, B.G.5
Park, Y.6
-
25
-
-
0141433189
-
Stimulating pd-1-negative signals concurrent with blocking cd154 co-stimulation induces long-Term islet allograft survival
-
Gao W, Demirci G, Strom TB, Li XC. Stimulating PD-1-negative signals concurrent with blocking CD154 co-stimulation induces long-Term islet allograft survival. Transplantation (2003) 76:994-9. doi:10.1097/01.TP.0000085010.39567.FB.
-
(2003)
Transplantation
, vol.76
, pp. 994-999
-
-
Gao, W.1
Demirci, G.2
Strom, T.B.3
Li, X.C.4
-
26
-
-
13544259967
-
Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with trail or programmed death-1 ligand
-
Hirata S, Senju S, Matsuyoshi H, Fukuma D, Uemura Y, and Nishimura Y. Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand. J Immunol. (2005) 174:1888-97. doi:10.4049/jimmunol.174.4.1888.
-
(2005)
J Immunol
, vol.174
, pp. 1888-1897
-
-
Hirata, S.1
Senju, S.2
Matsuyoshi, H.3
Fukuma, D.4
Uemura, Y.5
Nishimura, Y.6
-
27
-
-
17044411357
-
Il-12-independent light signaling enhances MHC class II disparate cd4+ t cell alloproliferation, IFN-responses, and intestinal graft-versus-host disease
-
Brown GR, Lee EL, El-Hayek J, Kintner K, Luck C. IL-12-independent LIGHT signaling enhances MHC class II disparate CD4+ T cell alloproliferation, IFN-responses, and intestinal graft-versus-host disease. J Immunol. (2005) 174:4688-95. doi:10.4049/jimmunol.174.8.4688.
-
(2005)
J Immunol
, vol.174
, pp. 4688-4695
-
-
Brown, G.R.1
Lee, E.L.2
El-Hayek, J.3
Kintner, K.4
Luck, C.5
-
28
-
-
0037128641
-
Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival
-
Ye Q, Fraser CC, Gao W, Wang L, Busfield SJ, Wang C, et al. Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival. J Exp Med. (2002) 195:795-800. doi:10.1084/jem.20012088.
-
(2002)
J Exp Med.
, vol.195
, pp. 795-800
-
-
Ye, Q.1
Fraser, C.C.2
Gao, W.3
Wang, L.4
Busfield, S.J.5
Wang, C.6
-
29
-
-
78649394507
-
Targeting of b and t lymphocyte associated (btla) prevents graft-versus-host disease without global immunosuppression
-
Albring JC, Sandau MM, Rapaport AS, Edelson BT, Satpathy A, Mashayekhi M, et al. Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression. J Exp Med. (2010) 207:2551-59. doi:10.1084/jem.20102017.
-
(2010)
J Exp Med
, vol.207
, pp. 2551-2559
-
-
Albring, J.C.1
Sandau, M.M.2
Rapaport, A.S.3
Edelson, B.T.4
Satpathy, A.5
Mashayekhi, M.6
-
30
-
-
79952178750
-
Dichotomous regulation of GVHD through bidirectional functions of the BTLA-hvem pathway
-
Sakoda Y, Park JJ, Zhao Y, Kuramasu A, Geng D, Liu Y, et al. Dichotomous regulation of GVHD through bidirectional functions of the BTLA-HVEM pathway. Blood (2011) 117:2506-14. doi:10.1182/blood-2010-08-301325.
-
(2011)
Blood
, vol.117
, pp. 2506-2514
-
-
Sakoda, Y.1
Park, J.J.2
Zhao, Y.3
Kuramasu, A.4
Geng, D.5
Liu, Y.6
-
31
-
-
85046807921
-
Functional anti-Tigit antibodies regulate development of autoimmunity and antitumor immunity
-
Dixon KO, Schorer M, Nevin J, Etminan Y, Amoozgar Z, Kondo T, et al. Functional Anti-TIGIT antibodies regulate development of autoimmunity and antitumor immunity. J Immunol. (2018) 200:3000-7 doi:10.4049/jimmunol.1700407.
-
(2018)
J Immunol
, vol.200
, pp. 3000-3007
-
-
Dixon, K.O.1
Schorer, M.2
Nevin, J.3
Etminan, Y.4
Amoozgar, Z.5
Kondo, T.6
-
32
-
-
30044434075
-
The TIM-3 ligand galectin-9 negatively regulates t helper type 1 immunity
-
Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khourys SJ, et al. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol. (2005) 6:1245-52. doi:10.1038/ni1271.
-
(2005)
Nat Immunol
, vol.6
, pp. 1245-1252
-
-
Zhu, C.1
Anderson, A.C.2
Schubart, A.3
Xiong, H.4
Imitola, J.5
Khourys, S.J.6
-
33
-
-
70350552096
-
Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice
-
He W, Fang Z, Wang F, Wu K, Xu Y, Zhou H, et al. Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation (2009) 88:782-90. doi:10.1097/TP.0b013e3181b47f25.
-
(2009)
Transplantation
, vol.88
, pp. 782-790
-
-
He, W.1
Fang, Z.2
Wang, F.3
Wu, K.4
Xu, Y.5
Zhou, H.6
-
34
-
-
41249096396
-
The tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft
-
Wang F, He W, Zhou H, Yuan J, Wu K, Xu L, et al. The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft. Cell Immunol. (2007) 250:68-74. doi:10.1016/j.cellimm.2008.01.006.
-
(2007)
Cell Immunol
, vol.250
, pp. 68-74
-
-
Wang, F.1
He, W.2
Zhou, H.3
Yuan, J.4
Wu, K.5
Xu, L.6
-
35
-
-
40849120400
-
Galectin-9 suppresses the generation of th17, promotes the induction of regulatory t cells, and regulates experimental autoimmune arthritis
-
Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, Watanabe K, et al. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol. (2008) 127:78-88. doi:10.1016/j.clim.2008.01.006.
-
(2008)
Clin Immunol
, vol.127
, pp. 78-88
-
-
Seki, M.1
Oomizu, S.2
Sakata, K.M.3
Sakata, A.4
Arikawa, T.5
Watanabe, K.6
-
36
-
-
0035206952
-
Cd200 immunoadhesin suppresses collagen-induced arthritis in mice
-
Gorczynski RM, Chen Z, Yu K, Hu J. CD200 immunoadhesin suppresses collagen-induced arthritis in mice. Clin Immunol. (2001) 101:328-34. doi:10.1006/clim.2001.5117.
-
(2001)
Clin Immunol
, vol.101
, pp. 328-334
-
-
Gorczynski, R.M.1
Chen, Z.2
Yu, K.3
Hu, J.4
-
37
-
-
42449121727
-
Cd200-fc, a novel antiarthritic biologic agent that targets proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis
-
Simelyte E, Criado G, Essex D, Uger RA, Feldmann M, Williams RO. CD200-Fc, a novel antiarthritic biologic agent that targets proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis. Arthritis Rheum. (2008) 58:1038-43. doi:10.1002/art.23378.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1038-1043
-
-
Simelyte, E.1
Criado, G.2
Essex, D.3
Uger, R.A.4
Feldmann, M.5
Williams, R.O.6
-
38
-
-
0037182893
-
A cd200fc immunoadhesin prolongs rat islet xenograft survival in mice
-
Gorczynski RM, Hu J, Chen Z, Kai Y, Lei J. A CD200FC immunoadhesin prolongs rat islet xenograft survival in mice. Transplantation (2002) 73:1948-53. doi:10.1097/00007890-200206270-00018.
-
(2002)
Transplantation
, vol.73
, pp. 1948-1953
-
-
Gorczynski, R.M.1
Hu, J.2
Chen, Z.3
Kai, Y.4
Lei, J.5
-
39
-
-
76649123575
-
Cd200r1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis
-
Liu Y, Bando Y, Vargas-Lowy D, Elyaman W, Khoury SJ, Huang T, et al. CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. J Neurosci. (2010) 30:2025-38. doi:10.1523/JNEUROSCI.4272-09.2010.
-
(2010)
J Neurosci
, vol.30
, pp. 2025-2038
-
-
Liu, Y.1
Bando, Y.2
Vargas-Lowy, D.3
Elyaman, W.4
Khoury, S.J.5
Huang, T.6
-
40
-
-
0036750535
-
Anti-cd200r ameliorates collagen-induced arthritis in mice
-
Gorczynski RM, Chen Z, Lee L, Yu K, Hu J. Anti-CD200R ameliorates collagen-induced arthritis in mice. Clin Immunol. (2002) 104:256-64. doi:10.1006/clim.2002.5232.
-
(2002)
Clin Immunol
, vol.104
, pp. 256-264
-
-
Gorczynski, R.M.1
Chen, Z.2
Lee, L.3
Yu, K.4
Hu, J.5
-
41
-
-
50049100345
-
A critical function for cd200 in lung immune homeostasis and the severity of influenza infection
-
Snelgrove RJ, Goulding J, Didierlaurent AM, Lyonga D, Vekaria S, Edwards L, et al. A critical function for CD200 in lung immune homeostasis and the severity of influenza infection. Nat Immunol. (2008) 9:1074-83. doi:10.1038/ni.1637.
-
(2008)
Nat Immunol
, vol.9
, pp. 1074-1083
-
-
Snelgrove, R.J.1
Goulding, J.2
Didierlaurent, A.M.3
Lyonga, D.4
Vekaria, S.5
Edwards, L.6
-
42
-
-
34548306817
-
Monoclonal antibody-mediated cd200 receptor signaling suppresses macrophage\ activation and tissue damage in experimental autoimmune uveoretinitis
-
Copland DA, Calder CJ, Raveney BJ, Nicholson LB, Phillips J, Cherwinski H, et al. Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage\ activation and tissue damage in experimental autoimmune uveoretinitis. Am J Pathol. (2007) 171:580-88. doi:10.2353/ajpath.2007.070272.
-
(2007)
Am J Pathol
, vol.171
, pp. 580-588
-
-
Copland, D.A.1
Calder, C.J.2
Raveney, B.J.3
Nicholson, L.B.4
Phillips, J.5
Cherwinski, H.6
-
43
-
-
84907353581
-
Agonistic cd200r1 DNA aptamers are potent immunosuppressants that prolong allogeneic skin graft survival
-
Prodeus A, Cydzik M, Abdul-Wahid A, Huang E, Khatri I, Gorczynski R, et al. Agonistic CD200R1 DNA aptamers are potent immunosuppressants that prolong allogeneic skin graft survival. Mol Ther Nucleic Acids (2014) 3:e190. doi:10.1038/mtna.2014.41.
-
(2014)
Mol Ther Nucleic Acids
, vol.3
, pp. e190
-
-
Prodeus, A.1
Cydzik, M.2
Abdul-Wahid, A.3
Huang, E.4
Khatri, I.5
Gorczynski, R.6
-
44
-
-
77954951434
-
Potent immunosuppression by a bivalent molecule binding to cd200r and tgf-betar
-
Gorczynski RM, Chen Z, Shivagnahnam S, Taseva A, Wong K, Yu K, et al. Potent immunosuppression by a bivalent molecule binding to CD200R and TGF-betaR. Transplantation (2010) 90:150-9. doi:10.1097/TP.0b013e3181e2d6a1.
-
(2010)
Transplantation
, vol.90
, pp. 150-159
-
-
Gorczynski, R.M.1
Chen, Z.2
Shivagnahnam, S.3
Taseva, A.4
Wong, K.5
Yu, K.6
-
45
-
-
80051930238
-
Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models
-
Flies DB, Wang S, Xu H, Chen L. Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models. J Immunol. (2011) 187:1537-41doi:10.4049/jimmunol.1100660.
-
(2011)
J Immunol
, vol.187
, pp. 1537-1541
-
-
Flies, D.B.1
Wang, S.2
Xu, H.3
Chen, L.4
-
46
-
-
84899722578
-
Coinhibitory receptor pd-1h preferentially suppresses cd4+ t cell-mediated immunity
-
Flies DB, Han X, Higuchi T, Zheng L, Sun J, Ye J, et al. Coinhibitory receptor PD-1H preferentially suppresses CD4+ T cell-mediated immunity. J Clin Invest. (2014) 124:1966-75. doi:10.1172/JCI74589.
-
(2014)
J Clin Invest
, vol.124
, pp. 1966-1975
-
-
Flies, D.B.1
Han, X.2
Higuchi, T.3
Zheng, L.4
Sun, J.5
Ye, J.6
-
47
-
-
85044347872
-
Vista.comp -An engineered checkpoint receptor agonist that potently suppresses t cell-mediated immune responses
-
Prodeus A, Abdul-Wahid A, Sparkes A, Fischer NW, Cydzik M, Chiang N, et al. VISTA.COMP -An engineered checkpoint receptor agonist that potently suppresses T cell-mediated immune responses. JCI Insight (2017) 2:e94308. doi:10.1172/jci.insight.94308.
-
(2017)
JCI Insight
, vol.2
, pp. e94308
-
-
Prodeus, A.1
Abdul-Wahid, A.2
Sparkes, A.3
Fischer, N.W.4
Cydzik, M.5
Chiang, N.6
-
48
-
-
0032875554
-
God must love galectins; he made so many of them
-
Cooper DN, Barondes SH. God must love galectins; he made so many of them. Glycobiology (1999) 9:979-84. doi:10.1093/glycob/9.10.979.
-
(1999)
Glycobiology
, vol.9
, pp. 979-984
-
-
Cooper, D.N.1
Barondes, S.H.2
-
49
-
-
12844268068
-
A coreceptor interaction between the cd28 and TNF receptor family members b and T\ lymphocyte attenuator and herpesvirus entry mediator
-
Gonzalez LC, Loyet KM, Calemine-Fenaux J, Chauhan V, Wranik B, Ouyang W, et al. A coreceptor interaction between the CD28 and TNF receptor family members B and T\ lymphocyte attenuator and herpesvirus entry mediator. Proc Natl Acad Sci USA. (2005) 102:1116-21. doi:10.1073/pnas.0409071102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1116-1121
-
-
Gonzalez, L.C.1
Loyet, K.M.2
Calemine-Fenaux, J.3
Chauhan, V.4
Wranik, B.5
Ouyang, W.6
-
50
-
-
64849105620
-
Herpesvirus entry mediator-ig treatment during immunization aggravates rheumatoid arthritis in the collagen-induced arthritis model
-
Pierer M, Schulz A, Rossol M, Kendzia E, Kyburz D, Haentzschel H, et al. Herpesvirus entry mediator-Ig treatment during immunization aggravates rheumatoid arthritis in the collagen-induced arthritis model. J Immunol. (2009) 182:3139-45. doi:10.4049/jimmunol.0713715.
-
(2009)
J Immunol
, vol.182
, pp. 3139-3145
-
-
Pierer, M.1
Schulz, A.2
Rossol, M.3
Kendzia, E.4
Kyburz, D.5
Haentzschel, H.6
-
51
-
-
0344500704
-
Potent activity of soluble b7-igg fusion proteins in therapy of established tumors and as vaccine adjuvant
-
Sturmhoefel K, Lee K, Gray GS, Thomas J, Zollner R, O'Toole M, et al. Potent activity of soluble B7-IgG fusion proteins in therapy of established tumors and as vaccine adjuvant. Cancer Res. (1999) 59:4964-72.
-
(1999)
Cancer Res
, vol.59
, pp. 4964-4972
-
-
Sturmhoefel, K.1
Lee, K.2
Gray, G.S.3
Thomas, J.4
Zollner, R.5
O'Toole, M.6
-
52
-
-
0031034123
-
Cd28-mediated induction of proliferation in resting t cells in vitro and in vivo without engagement of the t cell receptor: Evidence for functionally distinct forms of cd28
-
Tacke M, Hanke G, Hanke T, Hünig T. CD28-mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: Evidence for functionally distinct forms of CD28. Eur J Immunol. (1997) 27:239-47. doi:10.1002/eji.1830270136.
-
(1997)
Eur J Immunol
, vol.27
, pp. 239-247
-
-
Tacke, M.1
Hanke, G.2
Hanke, T.3
Hünig, T.4
-
53
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the ANTI-cd28 monoclonal antibody TGN1412
-
Suntharalingam G, Perry MR, Ward S, Brett SJ, Castello-Cortes A, Brunner MD, et al. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med. (2006). 355:1018-28. doi:10.1056/NEJMoa063842.
-
(2006)
N Engl J Med
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
-
54
-
-
27744512543
-
Functional analysis of b and t lymphocyte attenuator engagement on CD4+ AND CD8+ T cells
-
Krieg C, Han P, Stone R, Goularte OD, Kaye J. Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells. J Immunol. (2005) 175:6420-7. doi: 10.4049/jimmunol.175.10.6420.
-
(2005)
J Immunol
, vol.175
, pp. 6420-6427
-
-
Krieg, C.1
Han, P.2
Stone, R.3
Goularte, O.D.4
Kaye, J.5
-
55
-
-
14844357247
-
B and t lymphocyte attenuator exhibits structural and expression polymorphisms and is highly induced in anergic cd4+ t cells
-
Hurchla MA, Sedy JR, Gavrieli M, Gavrielli M, Drake CG, Murphy TL, et al. B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells. J Immunol. (2005) 174:3377-85. doi:10.4049/jimmunol.174.6.3377.
-
(2005)
J Immunol
, vol.174
, pp. 3377-3385
-
-
Hurchla, M.A.1
Sedy, J.R.2
Gavrieli, M.3
Gavrielli, M.4
Drake, C.G.5
Murphy, T.L.6
Et, A.7
-
56
-
-
19944431055
-
The cd200 receptor is a novel and potent regulator of murine and human mast cell \ function
-
Cherwinski HM, Murphy CA, Joyce BL, Bigler ME, Song YS, Zurawski SM, et al. The CD200 receptor is a novel and potent regulator of murine and human mast cell \ function. J Immunol. (2005) 174:1348-56. doi:10.4049/jimmunol.174.3.1348.
-
(2005)
J Immunol
, vol.174
, pp. 1348-1356
-
-
Cherwinski, H.M.1
Murphy, C.A.2
Joyce, B.L.3
Bigler, M.E.4
Song, Y.S.5
Zurawski, S.M.6
-
57
-
-
84929650544
-
Mechanistic assessment of pd-1h coinhibitory receptor-induced t cell tolerance to allogeneic antigens
-
Flies DB, Higuchi T, Chen L. Mechanistic assessment of PD-1H coinhibitory receptor-induced T cell tolerance to allogeneic antigens. J Immunol. (2015) 194:5294-304. doi:10.4049/jimmunol.1402648.
-
(2015)
J Immunol
, vol.194
, pp. 5294-5304
-
-
Flies, D.B.1
Higuchi, T.2
Chen, L.3
-
58
-
-
84961289524
-
Confusing signals: Recent progress in ctla-4 biology
-
Walker LS, Sansom DM. Confusing signals: Recent progress in CTLA-4 biology. Trends Immunol. (2015) 36:63-70. doi:10.1016/j.it.2014.12.001.
-
(2015)
Trends Immunol.
, vol.36
, pp. 63-70
-
-
Walker, L.S.1
Sansom, D.M.2
-
60
-
-
84953636175
-
Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in ctla-4
-
Lee S, Moon JS, Lee CR, Kim HE, Baek SM, Hwang S, et al. Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4. J Allergy Clin Immunol. (2016) 137:327-30. doi:10.1016/j.jaci.2015.08.036.
-
(2016)
J Allergy Clin Immunol.
, vol.137
, pp. 327-330
-
-
Lee, S.1
Moon, J.S.2
Lee, C.R.3
Kim, H.E.4
Baek, S.M.5
Hwang, S.6
-
61
-
-
10744233636
-
Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152)
-
Griffin MD, Hong DK, Holman PO, Lee KM, Whitters MJ, O'Herrin SM, et al. Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). J Immunol. (2000) 164:4433-42. doi:10.4049/jimmunol.164.9.4433.
-
(2000)
J Immunol
, vol.164
, pp. 4433-4442
-
-
Griffin, M.D.1
Hong, D.K.2
Holman, P.O.3
Lee, K.M.4
Whitters, M.J.5
O'Herrin, S.M.6
-
62
-
-
33746748176
-
Inhibition of T cell activation and autoimmune diabetes using a b cell surface-linked ctla-4 agonist
-
Fife BT, Griffin MD, Abbas AK, Locksley RM, Bluestone JA. Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. J Clin Invest. (2006) 116:2252-61. doi:10.1172/JCI27856.
-
(2006)
J Clin Invest
, vol.116
, pp. 2252-2261
-
-
Fife, B.T.1
Griffin, M.D.2
Abbas, A.K.3
Locksley, R.M.4
Bluestone, J.A.5
-
63
-
-
77951887482
-
Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of nzb/w f1 mice
-
Kasagi S, Kawano S, Okazaki T, Honjo T, Morinobu A, Hatachi S, et al. Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. J Immunol. (2010) 184:2337-47. doi:10.4049/jimmunol.0901652.
-
(2010)
J Immunol
, vol.184
, pp. 2337-2347
-
-
Kasagi, S.1
Kawano, S.2
Okazaki, T.3
Honjo, T.4
Morinobu, A.5
Hatachi, S.6
-
64
-
-
78650656619
-
Blockade of programmed death-1 in young (New Zealand black x New Zealand white)f1 mice promotes the activity of suppressive CD8+ t cells that protect from lupus-like disease
-
Wong M, La Cava A, Singh RP, Hahn BH. Blockade of programmed death-1 in young (New Zealand black x New Zealand white)F1 mice promotes the activity of suppressive CD8+ T cells that protect from lupus-like disease. J Immunol. (2010) 185:6563-71. doi:10.4049/jimmunol.0903401.
-
(2010)
J Immunol
, vol.185
, pp. 6563-6571
-
-
Wong, M.1
La, C.A.2
Singh, R.P.3
Hahn, B.H.4
-
65
-
-
84878069410
-
Blockade of programmed death-1 in young (New Zealand black x New Zealand white)f1 mice promotes the suppressive capacity of CD4+ regulatory t cells protecting from lupus-like disease
-
Wong M, La Cava A, Hahn BH. Blockade of programmed death-1 in young (New Zealand Black x New Zealand White)F1 mice promotes the suppressive capacity of CD4+ regulatory T cells protecting from lupus-like disease. J Immunol. (2013) 190:5402-10. doi:10.4049/jimmunol.1202382.
-
(2013)
J Immunol
, vol.190
, pp. 5402-5410
-
-
Wong, M.1
La, C.A.2
Hahn, B.H.3
-
66
-
-
85039444490
-
A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor b and t lymphocyte attenuator
-
Šedý JR, Balmert MO, Ware BC, Smith W, Nemcovicova I, Norris PS, et al. A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator. J Biol Chem. (2017) 292:21060-70. doi:10.1074/jbc.M117.813295.
-
(2017)
J Biol Chem
, vol.292
, pp. 21060-21070
-
-
Šedy, J.R.1
Balmert, M.O.2
Ware, B.C.3
Smith, W.4
Nemcovicova, I.5
Norris, P.S.6
-
67
-
-
36849017514
-
Programmed death-1 ligands-Transfected dendritic cells loaded with glutamic acid decarboxylase 65 (GAD65) inhibit both the alloresponse and the gad65-reactive lymphocyte response
-
He FR, Zhu HF, Huang H, Dai YD, Shen X, Wang M, et al. Programmed death-1 ligands-Transfected dendritic cells loaded with glutamic acid decarboxylase 65 (GAD65) inhibit both the alloresponse and the GAD65-reactive lymphocyte response. Clin Exp Immunol. (2008) 151:86-93. doi:10.1111/j.1365-2249.2007.03546.x.
-
(2008)
Clin Exp Immunol
, vol.151
, pp. 86-93
-
-
He, F.R.1
Zhu, H.F.2
Huang, H.3
Dai, Y.D.4
Shen, X.5
Wang, M.6
-
68
-
-
84866767643
-
A general requirement for fcriib co-engagement of agonistic anti-Tnfr antibodies
-
Li F, Ravetch JV. A general requirement for FcRIIB co-engagement of agonistic anti-TNFR antibodies. Cell Cycle (2012) 11:3343-44. doi:10.4161/cc.21842.
-
(2012)
Cell Cycle
, vol.11
, pp. 3343-3344
-
-
Li, F.1
Ravetch, J.V.2
-
69
-
-
84976493966
-
Therapeutic activity of agonistic, human anti-cd40 monoclonal antibodies requires selective fc?r engagement
-
Dahan R, Barnhart BC, Li F, Yamniuk AP, Korman AJ, Ravetch JV. Therapeutic activity of agonistic, human anti-CD40 monoclonal antibodies requires selective Fc?R engagement. Cancer Cell (2016) 29:820-31. doi:10.1016/j.ccell.2016.05.001.
-
(2016)
Cancer Cell
, vol.29
, pp. 820-831
-
-
Dahan, R.1
Barnhart, B.C.2
Li, F.3
Yamniuk, A.P.4
Korman, A.J.5
Ravetch, J.V.6
-
70
-
-
84922189761
-
Conformation of the human immunoglobulin g2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies
-
White AL, Chan HT, French RR, Willoughby J, Mockridge CI, Roghanian A, et al. Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies. Cancer Cell (2015) 27:138-48. doi:10.1016/j.ccell.2014.11.001.
-
(2015)
Cancer Cell
, vol.27
, pp. 138-148
-
-
White, A.L.1
Chan, H.T.2
French, R.R.3
Willoughby, J.4
Mockridge, C.I.5
Roghanian, A.6
-
71
-
-
84867423677
-
Non-catalytic tyrosine-phosphorylated receptors
-
Dushek O, Goyette J, van der Merwe PA. Non-catalytic tyrosine-phosphorylated receptors. Immunol Rev. (2012) 250:258-76. doi:10.1111/imr.12008.
-
(2012)
Immunol Rev.
, vol.250
, pp. 258-276
-
-
Dushek, O.1
Goyette, J.2
Van Der Merwe, A.3
-
72
-
-
33746114879
-
The kinetic-segregation model: Tcr triggering and beyond
-
Davis SJ, van der Merwe PA. The kinetic-segregation model: TCR triggering and beyond. Nat Immunol. (2006) 7:803-809. doi:10.1038/ni1369.
-
(2006)
Nat Immunol
, vol.7
, pp. 803-809
-
-
Davis, S.J.1
Van Der Merwe, A.2
-
73
-
-
84862180060
-
Investigating cell surface galectin-mediated cross-linking on glycoengineered cells
-
Belardi B, O'Donoghue GP, Smith AW, Groves JT, Bertozzi CR. Investigating cell surface galectin-mediated cross-linking on glycoengineered cells. J Am Chem Soc. (2012) 134:9549-52. doi:10.1021/ja301694s.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 9549-9552
-
-
Belardi, B.1
O'Donoghue, G.P.2
Smith, A.W.3
Groves, J.T.4
Bertozzi, C.R.5
-
74
-
-
85016395043
-
Impact of antibody subclass and disulfide isoform differences on the biological activity of cd200r and ßklotho agonist antibodies
-
Grujic O, Stevens J, Chou RY, Weiszmann JV, Sekirov L, Thomson C, et al. Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and ßklotho agonist antibodies. Biochem Biophys Res Commun. (2017) 486:985-91. doi:10.1016/j.bbrc.2017.03.145.
-
(2017)
Biochem Biophys Res Commun
, vol.486
, pp. 985-991
-
-
Grujic, O.1
Stevens, J.2
Chou, R.Y.3
Weiszmann, J.V.4
Sekirov, L.5
Thomson, C.6
-
75
-
-
84896514032
-
Cell contact-dependent priming and FC interaction with CD32+ immune cells contribute to the TGN1412-Triggered cytokine response
-
Bartholomaeus P, Semmler LY, Bukur T, Boisguerin V, Römer PS, Tabares P, et al. Cell contact-dependent priming and Fc interaction with CD32+ immune cells contribute to the TGN1412-Triggered cytokine response. J Immunol. (2014) 192:2091-2098. doi:10.4049/jimmunol.1302461.
-
(2014)
J Immunol
, vol.192
, pp. 2091-2098
-
-
Bartholomaeus, P.1
Semmler, L.Y.2
Bukur, T.3
Boisguerin, V.4
Römer, P.S.5
Tabares, P.6
-
76
-
-
84864751569
-
Development and characterisation of monoclonal antibodies specific for the murine inhibitory fc?riib (CD32B)
-
Williams EL, Tutt AL, French RR, Chan HT, Lau B, Penfold CA, et al. Development and characterisation of monoclonal antibodies specific for the murine inhibitory Fc?RIIB (CD32B). Eur J Immunol. (2012) 42:2109-2120. doi:10.1002/eji.201142302.
-
(2012)
Eur J Immunol.
, vol.42
, pp. 2109-2120
-
-
Williams, E.L.1
Tutt, A.L.2
French, R.R.3
Chan, H.T.4
Lau, B.5
Penfold, C.A.6
-
77
-
-
85042373437
-
A reappraisal of ctla-4 checkpoint blockade in cancer immunotherapy
-
Du X, Tang F, Liu M, Su J, Zhang Y, Wu W, et al. A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy. Cell Res. (2018) 28:416-32. doi:10.1038/s41422-018-0011-0.
-
(2018)
Cell Res
, vol.28
, pp. 416-432
-
-
Du, X.1
Tang, F.2
Liu, M.3
Su, J.4
Zhang, Y.5
Wu, W.6
-
78
-
-
78649734504
-
Monoclonal antibodies to b and t lymphocyte attenuator (BTLA) have no effect on in vitro b cell proliferation and act to inhibit in vitro t cell proliferation when presented in a CIS, but not trans, format relative to the activating stimulus
-
Zhang M, Howard K, Winters A, Steavenson S, Anderson S, Smelt S, et al. Monoclonal antibodies to B and T lymphocyte attenuator (BTLA) have no effect on in vitro B cell proliferation and act to inhibit in vitro T cell proliferation when presented in a cis, but not trans, format relative to the activating stimulus. Clin Exp Immunol. (2011) 163:77-87. doi:10.1111/j.1365-2249.2010.04259.
-
(2011)
Clin Exp Immunol
, vol.163
, pp. 77-87
-
-
Zhang, M.1
Howard, K.2
Winters, A.3
Steavenson, S.4
Anderson, S.5
Smelt, S.6
-
79
-
-
0042505740
-
Topological requirements and signaling properties of t cell-Activating, ANTI-CD28 antibody superagonists
-
Lühder F, Huang Y, Dennehy KM, Guntermann C, Müller I, Winkler E, et al. Topological requirements and signaling properties of T cell-Activating, anti-CD28 antibody superagonists. J Exp Med. (2003) 197:955-66. doi:10.1084/jem.20021024.
-
(2003)
J Exp Med
, vol.197
, pp. 955-966
-
-
Lühder, F.1
Huang, Y.2
Dennehy, K.M.3
Guntermann, C.4
Müller, I.5
Winkler, E.6
-
80
-
-
20144376352
-
Crystal structure of a soluble CD28-fab complex
-
Evans EJ, Esnouf RM, Manso-Sancho R, Gilbert RJ, James JR, Yu C, et al. Crystal structure of a soluble CD28-Fab complex. Nat Immunol. (2005) 6:271-9. doi:10.1038/ni1170.
-
(2005)
Nat Immunol
, vol.6
, pp. 271-279
-
-
Evans, E.J.1
Esnouf, R.M.2
Manso-Sancho, R.3
Gilbert, R.J.4
James, J.R.5
Yu, C.6
-
81
-
-
45549093089
-
Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane
-
James SE, Greenberg PD, Jensen MC, Lin Y, Wang J, Till BG, et al. Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane. J Immunol. (2008) 180:7028-38. doi:10.4049/jimmunol.180.10.7028.
-
(2008)
J Immunol
, vol.180
, pp. 7028-7038
-
-
James, S.E.1
Greenberg, P.D.2
Jensen, M.C.3
Lin, Y.4
Wang, J.5
Till, B.G.6
-
82
-
-
85014064309
-
Membrane-proximal epitope facilitates efficient T cell synapse formation by ANTI-FCRH5/CD3 and is a requirement for myeloma cell killing
-
Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, et al. Membrane-proximal epitope facilitates efficient T cell synapse formation by anti-FcRH5/CD3 and is a requirement for myeloma cell killing. Cancer Cell (2017) 31:383-95. doi:10.1016/j.ccell.2017.02.001.
-
(2017)
Cancer Cell
, vol.31
, pp. 383-395
-
-
Li, J.1
Stagg, N.J.2
Johnston, J.3
Harris, M.J.4
Menzies, S.A.5
DiCara, D.6
-
83
-
-
0032532284
-
CD3/TCR complex-Associated lymphocyte activation gene-3 molecules inhibit cd3/tcr signaling
-
Hannier S, Tournier M, Bismuth G, Triebel F. CD3/TCR complex-Associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling. J Immunol. (1998) 161:4058-65.
-
(1998)
J Immunol
, vol.161
, pp. 4058-4065
-
-
Hannier, S.1
Tournier, M.2
Bismuth, G.3
Triebel, F.4
-
84
-
-
84954389695
-
Immunotherapy and hypophysitis: Clinical presentation, treatment, and biologic insights
-
Faje A. Immunotherapy and hypophysitis: clinical presentation, treatment, and biologic insights. Pituitary (2016) 19:82-92. doi:10.1007/s11102-015-0671-4.
-
(2016)
Pituitary
, vol.19
, pp. 82-92
-
-
Faje, A.1
-
85
-
-
77956302693
-
Primate testing of tgn1412: Right target, wrong cell
-
Pallardy M, Hünig T. Primate testing of TGN1412: Right target, wrong cell. Br J Pharmacol. (2010) 161:509-11. doi:10.1111/j.1476-5381.2010.00925.x.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 509-511
-
-
Pallardy, M.1
Hünig, T.2
-
86
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, Postow MA, Rizvi NA, Lesokhin AM, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. (2013) 369:122-33. doi:10.1056/NEJMoa1302369.
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
-
87
-
-
79951684125
-
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
-
Okazaki T, Okazaki IM, Wang J, Sugiura D, Nakaki F, Yoshida T, et al. PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice. J Exp Med. (2011) 208:395-407. doi:10.1084/jem.20100466.
-
(2011)
J Exp Med
, vol.208
, pp. 395-407
-
-
Okazaki, T.1
Okazaki, I.M.2
Wang, J.3
Sugiura, D.4
Nakaki, F.5
Yoshida, T.6
-
88
-
-
84930208138
-
Immune-checkpoint proteins vista and PD-1 nonredundantly regulate murine T-cell responses
-
Liu J, Yuan Y, Chen W, Putra J, Suriawinata AA, Schenk AD, et al. Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses. Proc Natl Acad Sci USA. (2015) 112:6682-7. doi:10.1073/pnas.1420370112.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 6682-6687
-
-
Liu, J.1
Yuan, Y.2
Chen, W.3
Putra, J.4
Suriawinata, A.A.5
Schenk, A.D.6
-
89
-
-
84884561907
-
Molecular pathways: Coexpression of immune checkpoint molecules: Signaling pathways and implications for cancer immunotherapy
-
Nirschl CJ, Drake CG. Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin Cancer Res. (2013) 19:4917-24. doi:10.1158/1078-0432.CCR-12-1972.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4917-4924
-
-
Nirschl, C.J.1
Drake, C.G.2
-
90
-
-
84890802572
-
Targeting co-stimulatory pathways: Transplantation and autoimmunity
-
Ford ML, Adams AB, Pearson TC. Targeting co-stimulatory pathways: Transplantation and autoimmunity. Nat Rev Nephrol. (2014) 10:14-24. doi:10.1038/nrneph.2013.183.
-
(2014)
Nat Rev Nephrol
, vol.10
, pp. 14-24
-
-
Ford, M.L.1
Adams, A.B.2
Pearson, T.C.3
-
91
-
-
84903700330
-
Co-inhibitory pathways and their importance in immune regulation
-
Murakami N, Riella LV. Co-inhibitory pathways and their importance in immune regulation. Transplantation (2014) 98:3-14. doi:10.1097/TP.0000000000000169.
-
(2014)
Transplantation
, vol.98
, pp. 3-14
-
-
Murakami, N.1
Riella, L.V.2
-
92
-
-
84966928985
-
Co-stimulatory and co-inhibitory pathways in autoimmunity
-
Zhang Q, Vignali DA. Co-stimulatory and co-inhibitory pathways in autoimmunity. Immunity (2016) 44:1034-51. doi:10.1016/j.immuni.2016.04.017.
-
(2016)
Immunity
, vol.44
, pp. 1034-1051
-
-
Zhang, Q.1
Vignali, D.A.2
|