-
1
-
-
0030300154
-
The complexities of T-cell co-stimulation: CD28 and beyond
-
Sperling, A. I., and J. A. Bluestone. 1996. The complexities of T-cell co-stimulation: CD28 and beyond. Immunol. Rev. 153:155-182.
-
(1996)
Immunol. Rev.
, vol.153
, pp. 155-182
-
-
Sperling, A.I.1
Bluestone, J.A.2
-
2
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir, M. E., S. C. Liang, I. Guleria, Y. E. Latchman, A. Qipo, L. A. Albacker, M. Koulmanda, G. J. Freeman, M. H. Sayegh, and A. H. Sharpe. 2006. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J. Exp. Med. 203:883-895.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
Latchman, Y.E.4
Qipo, A.5
Albacker, L.A.6
Koulmanda, M.7
Freeman, G.J.8
Sayegh, M.H.9
Sharpe, A.H.10
-
3
-
-
33751552197
-
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway
-
Fife, B. T., I. Guleria, M. Gubbels Bupp, T. N. Eagar, Q. Tang, H. Bour-Jordan, H. Yagita, M. Azuma, M. H. Sayegh, and J. A. Bluestone. 2006. Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. J. Exp. Med. 203:2737-2747.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2737-2747
-
-
Fife, B.T.1
Guleria, I.2
Bupp, M.G.3
Eagar, T.N.4
Tang, Q.5
Bour-Jordan, H.6
Yagita, H.7
Azuma, M.8
Sayegh, M.H.9
Bluestone, J.A.10
-
4
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe, A. H., E. J. Wherry, R. Ahmed, and G. J. Freeman. 2007. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat. Immunol. 8:239-245.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
5
-
-
33645863160
-
The PD-1-PD-L pathway in immunological tolerance
-
Okazaki, T., and T. Honjo. 2006. The PD-1-PD-L pathway in immunological tolerance. Trends Immunol. 27:195-201.
-
(2006)
Trends Immunol.
, vol.27
, pp. 195-201
-
-
Okazaki, T.1
Honjo, T.2
-
6
-
-
0037307930
-
Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
-
Brown, J. A., D. M. Dorfman, F. R. Ma, E. L. Sullivan, O. Munoz, C. R. Wood, E. A. Greenfield, and G. J. Freeman. 2003. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J. Immunol. 170:1257-1266.
-
(2003)
J. Immunol.
, vol.170
, pp. 1257-1266
-
-
Brown, J.A.1
Dorfman, D.M.2
Ma, F.R.3
Sullivan, E.L.4
Munoz, O.5
Wood, C.R.6
Greenfield, E.A.7
Freeman, G.J.8
-
7
-
-
0036785604
-
B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis
-
Mazanet, M. M., and C. C. Hughes. 2002. B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis. J. Immunol. 169:3581-3588.
-
(2002)
J. Immunol.
, vol.169
, pp. 3581-3588
-
-
Mazanet, M.M.1
Hughes, C.C.2
-
8
-
-
0041845131
-
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism
-
Blazar, B. R., B. M. Carreno, A. Panoskaltsis-Mortari, L. Carter, Y. Iwai, H. Yagita, H. Nishimura, and P. A. Taylor. 2003. Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism. J. Immunol. 171:1272-1277.
-
(2003)
J. Immunol.
, vol.171
, pp. 1272-1277
-
-
Blazar, B.R.1
Carreno, B.M.2
Panoskaltsis-Mortari, A.3
Carter, L.4
Iwai, Y.5
Yagita, H.6
Nishimura, H.7
Taylor, P.A.8
-
9
-
-
0037477604
-
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis
-
Salama, A. D., T. Chitnis, J. Imitola, M. J. Ansari, H. Akiba, F. Tushima, M. Azuma, H. Yagita, M. H. Sayegh, and S. J. Khoury. 2003. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J. Exp. Med. 198:71-78.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 71-78
-
-
Salama, A.D.1
Chitnis, T.2
Imitola, J.3
Ansari, M.J.4
Akiba, H.5
Tushima, F.6
Azuma, M.7
Yagita, H.8
Sayegh, M.H.9
Khoury, S.J.10
-
10
-
-
0041419629
-
-
Published erratum appears in
-
[Published erratum appears in 2003 J. Exp. Med. 198:677.]
-
(2003)
J. Exp. Med.
, vol.198
, pp. 677
-
-
-
11
-
-
13244277850
-
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
-
Prokunina, L., C. Castillejo-López, F. Oberg, I. Gunnarsson, L. Berg, V. Magnusson, A. J. Brookes, D. Tentler, H. Kristjansdóttir, G. Gröndal, et al. 2002. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat. Genet. 32:666-669.
-
(2002)
Nat. Genet.
, vol.32
, pp. 666-669
-
-
Prokunina, L.1
Castillejo-López, C.2
Oberg, F.3
Gunnarsson, I.4
Berg, L.5
Magnusson, V.6
Brookes, A.J.7
Tentler, D.8
Kristjansdóttir, H.9
Gröndal, G.10
-
12
-
-
33751094550
-
Programmed death-1 gene polymorphisms in patients with systemic lupus erythematosus in Taiwan
-
Wang, S. C., Y. J. Chen, T. T. Ou, C. C. Wu, W. C. Tsai, H. W. Liu, and J. H. Yen. 2006. Programmed death-1 gene polymorphisms in patients with systemic lupus erythematosus in Taiwan. J. Clin. Immunol. 26:506-511.
-
(2006)
J. Clin. Immunol.
, vol.26
, pp. 506-511
-
-
Wang, S.C.1
Chen, Y.J.2
Ou, T.T.3
Wu, C.C.4
Tsai, W.C.5
Liu, H.W.6
Yen, J.H.7
-
13
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura, H., M. Nose, H. Hiai, N. Minato, and T. Honjo. 1999. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11:141-151.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
14
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
Nishimura, H., T. Okazaki, Y. Tanaka, K. Nakatani, M. Hara, A. Matsumori, S. Sasayama, A. Mizoguchi, H. Hiai, N. Minato, and T. Honjo. 2001. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 291:319-322.
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
Nakatani, K.4
Hara, M.5
Matsumori, A.6
Sasayama, S.7
Mizoguchi, A.8
Hiai, H.9
Minato, N.10
Honjo, T.11
-
15
-
-
42149151044
-
PConsensus peptide induces tolerogenic CD8+ T cells in lupus-prone (NZB x NZW) F1 mice by differentially regulating Foxp3 and PD1 molecules
-
Singh, R. P., A. la Cava, and B. H. Hahn. 2008. pConsensus peptide induces tolerogenic CD8+ T cells in lupus-prone (NZB x NZW) F1 mice by differentially regulating Foxp3 and PD1 molecules. J. Immunol. 180:2069-2080.
-
(2008)
J. Immunol.
, vol.180
, pp. 2069-2080
-
-
Singh, R.P.1
La Cava, A.2
Hahn, B.H.3
-
16
-
-
28244494166
-
Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors
-
Hahn, B. H., R. P. Singh, A. la Cava, and F. M. Ebling. 2005. Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors. J. Immunol. 175:7728-7737.
-
(2005)
J. Immunol.
, vol.175
, pp. 7728-7737
-
-
Hahn, B.H.1
Singh, R.P.2
La Cava, A.3
Ebling, F.M.4
-
17
-
-
4344634278
-
Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White) F1 mice suppress in vitro production of antibodies to DNA
-
La Cava, A., F. M. Ebling, and B. H. Hahn. 2004. Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White) F1 mice suppress in vitro production of antibodies to DNA. J. Immunol. 173:3542-3548.
-
(2004)
J. Immunol.
, vol.173
, pp. 3542-3548
-
-
Cava, A.1
Ebling, F.M.2
Hahn, B.H.3
-
18
-
-
0035092481
-
Treatment with a consensus peptide based on amino acid sequences in autoantibodies prevents T cell activation by autoantigens and delays disease onset in murine lupus
-
Hahn, B. H., R. R. Singh, W. K. Wong, B. P. Tsao, K. Bulpitt, and F. M. Ebling. 2001. Treatment with a consensus peptide based on amino acid sequences in autoantibodies prevents T cell activation by autoantigens and delays disease onset in murine lupus. Arthritis Rheum. 44:432-441.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 432-441
-
-
Hahn, B.H.1
Singh, R.R.2
Wong, W.K.3
Tsao, B.P.4
Bulpitt, K.5
Ebling, F.M.6
-
19
-
-
0028232565
-
Comparison of pathogenic and non-pathogenic murine antibodies to DNA: Antigen binding and structural characteristics
-
Ohnishi, K., F. M. Ebling, B. Mitchell, R. R. Singh, B. H. Hahn, and B. P. Tsao. 1994. Comparison of pathogenic and non-pathogenic murine antibodies to DNA: antigen binding and structural characteristics. Int. Immunol. 6:817-830.
-
(1994)
Int. Immunol.
, vol.6
, pp. 817-830
-
-
Ohnishi, K.1
Ebling, F.M.2
Mitchell, B.3
Singh, R.R.4
Hahn, B.H.5
Tsao, B.P.6
-
20
-
-
0025159214
-
Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus
-
Tsao, B. P., F. M. Ebling, C. Roman, N. Panosian-Sahakian, K. Calame, and B. H. Hahn. 1990. Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus. J. Clin. Invest. 85:530-540.
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 530-540
-
-
Tsao, B.P.1
Ebling, F.M.2
Roman, C.3
Panosian-Sahakian, N.4
Calame, K.5
Hahn, B.H.6
-
21
-
-
34250222393
-
CD8+ T cell-mediated suppression of autoimmunity in a murine lupus model of peptide-induced immune tolerance depends on Foxp3 expression
-
Singh, R. P., A. la Cava, M. Wong, F. M. Ebling, and B. H. Hahn. 2007. CD8+ T cell-mediated suppression of autoimmunity in a murine lupus model of peptide-induced immune tolerance depends on Foxp3 expression. J. Immunol. 178:7649-7657.
-
(2007)
J. Immunol.
, vol.178
, pp. 7649-7657
-
-
Singh, R.P.1
La Cava, A.2
Wong, M.3
Ebling, F.M.4
Hahn, B.H.5
-
22
-
-
0028849856
-
Immune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus
-
Singh, R. R., F. M. Ebling, E. E. Sercarz, and B. H. Hahn. 1995. Immune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus. J. Clin. Invest. 96:2990-2996.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2990-2996
-
-
Singh, R.R.1
Ebling, F.M.2
Sercarz, E.E.3
Hahn, B.H.4
-
23
-
-
34547164535
-
Overview of pathogenesis of systemic lupus erythematosus
-
D. Wallace, and B. H. Hahn, eds. Lippincott Williams & Wilkins, Philadelphia
-
Hahn, B. H. 2006. Overview of pathogenesis of systemic lupus erythematosus. In Dubois' Lupus Erythematosus. D. Wallace, and B. H. Hahn, eds. Lippincott Williams & Wilkins, Philadelphia, p. 46-53.
-
(2006)
Dubois' Lupus Erythematosus
, pp. 46-53
-
-
Hahn, B.H.1
-
24
-
-
77951887482
-
Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice
-
Kasagi, S., S. Kawano, T. Okazaki, T. Honjo, A. Morinobu, S. Hatachi, K. Shimatani, Y. Tanaka, N. Minato, and S. Kumagai. 2010. Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. J. Immunol. 184:2337-2347.
-
(2010)
J. Immunol.
, vol.184
, pp. 2337-2347
-
-
Kasagi, S.1
Kawano, S.2
Okazaki, T.3
Honjo, T.4
Morinobu, A.5
Hatachi, S.6
Shimatani, K.7
Tanaka, Y.8
Minato, N.9
Kumagai, S.10
-
26
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber, D. L., E. J. Wherry, D. Masopust, B. Zhu, J. P. Allison, A. H. Sharpe, G. J. Freeman, and R. Ahmed. 2006. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439:682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
27
-
-
33749009709
-
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
-
Trautmann, L., L. Janbazian, N. Chomont, E. A. Said, S. Gimmig, B. Bessette, M. R. Boulassel, E. Delwart, H. Sepulveda, R. S. Balderas, et al. 2006. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat. Med. 12:1198-1202.
-
(2006)
Nat. Med.
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
-
28
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day, C. L., D. E. Kaufmann, P. Kiepiela, J. A. Brown, E. S. Moodley, S. Reddy, E. W. Mackey, J. D. Miller, A. J. Leslie, C. DePierres, et al. 2006. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443:350-354.
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
-
29
-
-
0034600786
-
HIV-specific CD8 (+) T cells produce antiviral cytokines but are impaired in cytolytic function
-
Appay, V., D. F. Nixon, S. M. Donahoe, G. M. Gillespie, T. Dong, A. King, G. S. Ogg, H. M. Spiegel, C. Conlon, C. A. Spina, et al. 2000. HIV-specific CD8 (+) T cells produce antiviral cytokines but are impaired in cytolytic function. J. Exp. Med. 192:63-75.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 63-75
-
-
Appay, V.1
Nixon, D.F.2
Donahoe, S.M.3
Gillespie, G.M.4
Dong, T.5
King, A.6
Ogg, G.S.7
Spiegel, H.M.8
Conlon, C.9
Spina, C.A.10
-
30
-
-
0032416085
-
Viral immune evasion due to persistence of activated T cells without effector function
-
Zajac, A. J., J. N. Blattman, K. Murali-Krishna, D. J. Sourdive, M. Suresh, J. D. Altman, and R. Ahmed. 1998. Viral immune evasion due to persistence of activated T cells without effector function. J. Exp. Med. 188:2205-2213.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2205-2213
-
-
Zajac, A.J.1
Blattman, J.N.2
Murali-Krishna, K.3
Sourdive, D.J.4
Suresh, M.5
Altman, J.D.6
Ahmed, R.7
|