Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica

Journal of Neuroinflammation

Volumn 15, Issue 1, 2018, Pages

  Duan, Tianjiao ^a,b   Smith, Alex J ^a   Verkman, Alan S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Aquaporin 4; Astrocyte; Complement; Neuron; NMO

Indexed keywords

AQUAPORIN 4; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C6; COMPLEMENT INHIBITOR; COMPLEMENT MEMBRANE ATTACK COMPLEX; FLUORESCENT DYE; IMMUNOGLOBULIN G; CD59 ANTIGEN; NERVE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE CULTURE; BRAIN CELL; BYSTANDER EFFECT; CELL DEATH; COCULTURE; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; COMPLEMENT DEPOSITION; CONTROLLED STUDY; IMMUNOFLUORESCENCE; KNOCKOUT RAT; MYELOOPTIC NEUROPATHY; NERVE CELL; NERVE CELL CULTURE; NERVE CELL LESION; NERVE CELL NECROSIS; NONHUMAN; RAT; ANIMAL; ASTROCYTE; BLOOD; BRAIN CORTEX; CELL CULTURE; CHEMICALLY INDUCED; CONDITIONED MEDIUM; CYTOLOGY; DEFICIENCY; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; IMMUNOLOGY; MAMMALIAN EMBRYO; METABOLISM; PHARMACOLOGY; TIME FACTOR; TRANSGENIC RAT;

ANIMALS; AQUAPORIN 4; ASTROCYTES; CD59 ANTIGENS; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; COMPLEMENT C1Q; COMPLEMENT MEMBRANE ATTACK COMPLEX; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN G; NERVE TISSUE PROTEINS; NEUROMYELITIS OPTICA; NEURONS; RATS; RATS, TRANSGENIC; TIME FACTORS;

EID: 85055170357     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-018-1333-z     Document Type: Article

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