Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury

Brain

Volumn 133, Issue 9, 2010, Pages 2578-2591

  Marignier, Romain ^a,b,c   Nicolle, Adeline ^b,c   Watrin, Chantal ^b,c   Touret, Monique ^b,c   Cavagna, Sylvie ^b,c   Varrin Doyer, Michel ^b,c   Cavillon, Gaëlle ^b,c   Rogemond, Véronique ^b,c   Confavreux, Christian ^a,b,c   Honnorat, Jérôme ^b,c   Giraudon, Pascale ^b,c  

^a HÔPITAL NEUROLOGIQUE   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

aquaporin 4; astrocyte; autoimmunity; demyelination; Devic's disease

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; AQUAPORIN 4; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; IMMUNOGLOBULIN G; MYELIN BASIC PROTEIN; VESICULAR GLUTAMATE TRANSPORTER 1; 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; AQP4 PROTEIN, HUMAN; CASPASE 3; DPYSL5 PROTEIN, HUMAN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE PROTEIN; NR2B NMDA RECEPTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; ASTROCYTE; BYSTANDER EFFECT; CELL CONTACT; CELL FUNCTION; CONTROLLED STUDY; DEMYELINATION; ENZYME ACTIVITY; EXCITOTOXICITY; FLOW CYTOMETRY; GLIA CELL; MYELITIS; MYELOOPTIC NEUROPATHY; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OLIGODENDROGLIA; OPTIC NERVE; OPTIC NEURITIS; PRIORITY JOURNAL; PURIFICATION; RAT; SPINAL CORD; ADOLESCENT; ADULT; ANIMAL; BLOOD; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; FEMALE; GENETIC TRANSFECTION; HUMAN; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; NEWBORN; NONPARAMETRIC TEST; PATHOLOGY; PHYSIOLOGY; PROCEDURES; TIME; YOUNG ADULT;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ADOLESCENT; ADULT; ANIMALS; ANIMALS, NEWBORN; AQUAPORIN 4; ASTROCYTES; CASPASE 3; CELLS, CULTURED; CEREBRAL CORTEX; FEMALE; FLOW CYTOMETRY; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE-AMMONIA LIGASE; GLUTAMIC ACID; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; MYELIN BASIC PROTEIN; NERVE TISSUE PROTEINS; NEUROMYELITIS OPTICA; OLIGODENDROGLIA; OPTIC NERVE; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; STATISTICS, NONPARAMETRIC; TIME FACTORS; TRANSFECTION; YOUNG ADULT;

EID: 77956383249     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq177     Document Type: Article

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