Highly encephalitogenic aquaporin 4-specific T cells and NMO-IgG jointly orchestrate lesion location and tissue damage in the CNS

Acta Neuropathologica

Volumn 130, Issue 6, 2015, Pages 783-798

  Zeka, Bleranda ^a   Hastermann, Maria ^a   Hochmeister, Sonja ^b   Kögl, Nikolaus ^a   Kaufmann, Nathalie ^a   Schanda, Kathrin ^c   Mader, Simone ^c   Misu, Tatsuro ^d   Rommer, Paulus ^a   Fujihara, Kazuo ^d   Illes, Zsolt ^e   Leutmezer, Fritz ^a   Sato, Douglas Kazutoshi ^d,f   Nakashima, Ichiro ^d   Reindl, Markus ^c   Lassmann, Hans ^a   Bradl, Monika ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^f UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aquaporin 4; CNS inflammation; ENMO; Neuromyelitis optica; T cells

Indexed keywords

AQUAPORIN 4; EPITOPE; IMMUNOGLOBULIN G; AQP4 PROTEIN, HUMAN; GAMMA INTERFERON; IL17 PROTEIN, RAT; INTERLEUKIN 17;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN; BRAIN REGION; CELL INFILTRATION; CELL SPECIFICITY; GRAY MATTER; HYPOTHALAMUS; MENINX; MYELOOPTIC NEUROPATHY; NERVE FIBER; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OPTIC NERVE; PANENCEPHALITIS; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL CORD DORSAL HORN; T LYMPHOCYTE; ANIMAL; CELL LINE; CENTRAL NERVOUS SYSTEM; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENETICS; HUMAN; IMMUNOLOGY; LEWIS RAT; METABOLISM; PATHOLOGY;

ANIMALS; AQUAPORIN 4; ASTROCYTES; CELL LINE; CENTRAL NERVOUS SYSTEM; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-17; NEUROMYELITIS OPTICA; OPTIC NERVE; RATS, INBRED LEW; T-LYMPHOCYTES;

EID: 84947616010     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1501-5     Document Type: Article

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