Test of the ’glymphatic’ hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

eLife

Volumn 6, Issue , 2017, Pages

  Smith, Alex J ^a,b   Yao, Xiaoming ^a,b   Dix, James A ^a,b   Jin, Byung Ju ^a,b   Verkman, Alan S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 4; DEXTRAN; ALEXA FLUOR 647; AQP4 PROTEIN, MOUSE; CARBOCYANINE; FLUORESCEIN DERIVATIVE; FLUORESCEIN-DEXTRAN; FLUORESCENT DYE;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; AQP4 GENE; ARTICLE; ASTROCYTE; BLEACHING; BRAIN CORTEX; BRAIN TISSUE; CARDIOPULMONARY INSUFFICIENCY; CELL TRANSPORT; CEREBROSPINAL FLUID; CONFOCAL MICROSCOPY; DRUG PENETRATION; FLUORESCENCE; GENE; GENE DELETION; IMAGE ANALYSIS; MATHEMATICAL MODEL; MOUSE; NONHUMAN; OLIGOMERIZATION; SWELLING; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DEFICIENCY; DIFFUSION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION; GENETICS; HEART ARREST; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; PARENCHYMA; RAT; SUBARACHNOID SPACE; TRANSPORT AT THE CELLULAR LEVEL; ULTRASTRUCTURE;

ANIMALS; AQUAPORIN 4; BIOLOGICAL TRANSPORT; CARBOCYANINES; DEXTRANS; DIFFUSION; FLUORESCEINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENT DYES; GENE EXPRESSION; HEART ARREST; INJECTIONS, INTRAVENTRICULAR; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PARENCHYMAL TISSUE; RATS; SUBARACHNOID SPACE;

EID: 85029231897     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.27679     Document Type: Article

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