메뉴 건너뛰기




Volumn 33, Issue 10, 2012, Pages 2237-2246

Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex

Author keywords

Alzheimer's disease; C5b 9; Complement C9 protein; Macular degeneration; Paroxysmal nocturnal hemoglobinuria

Indexed keywords

AURIN HEXACARBOXYLIC ACID; AURIN QUADRACARBOXYLIC ACID; AURINTRICARBOXYLIC ACID; CARBOXYLIC ACID; COMPLEMENT C5B 8; COMPLEMENT COMPONENT C5B; COMPLEMENT COMPONENT C9; COMPLEMENT MEMBRANE ATTACK COMPLEX; UNCLASSIFIED DRUG;

EID: 84861739864     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.12.005     Document Type: Article
Times cited : (27)

References (49)
  • 1
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson D.H., Mullins R.F., Hageman G.S., Johnson L.V. A role for local inflammation in the formation of drusen in the aging eye. Am. J. Ophthalmol 2002, 134:411-431.
    • (2002) Am. J. Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 3
    • 33748780095 scopus 로고    scopus 로고
    • Role of complement in neurodegeneration and neuroinflammation
    • Bonifati D.M., Kishore U. Role of complement in neurodegeneration and neuroinflammation. Mol. Immunol 2007, 44:999-1010.
    • (2007) Mol. Immunol , vol.44 , pp. 999-1010
    • Bonifati, D.M.1    Kishore, U.2
  • 4
    • 0025322247 scopus 로고
    • Synthesis of the covalent hydrate of the incorrectly assumed structure of Aurintricarboxylic acid (ATA)
    • Cushman M., Kanamathareddy S. Synthesis of the covalent hydrate of the incorrectly assumed structure of Aurintricarboxylic acid (ATA). Tetrahedron 1990, 46:1491-1498.
    • (1990) Tetrahedron , vol.46 , pp. 1491-1498
    • Cushman, M.1    Kanamathareddy, S.2
  • 5
    • 0027102113 scopus 로고
    • Structural investigation and anti-HIV activities of high molecular weight ATA polymers
    • Cushman M., Wang P., Stowell J.G., Schols D., De Clercq E. Structural investigation and anti-HIV activities of high molecular weight ATA polymers. J. Org. Chem 1992, 57:7241-7248.
    • (1992) J. Org. Chem , vol.57 , pp. 7241-7248
    • Cushman, M.1    Wang, P.2    Stowell, J.G.3    Schols, D.4    De Clercq, E.5
  • 6
    • 0025969493 scopus 로고
    • Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds
    • Cushman M., Kanamathareddy S., De Clercq E., Schols D., Goldman M.E., Bowen J.A. Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds. J. Med. Chem 1991, 34:337-342.
    • (1991) J. Med. Chem , vol.34 , pp. 337-342
    • Cushman, M.1    Kanamathareddy, S.2    De Clercq, E.3    Schols, D.4    Goldman, M.E.5    Bowen, J.A.6
  • 7
    • 0019993831 scopus 로고
    • Immunoglobulins and complement factors in senile plaques: an immunoperoxidase study
    • Eikelenboom P., Stam F.C. Immunoglobulins and complement factors in senile plaques: an immunoperoxidase study. Acta Neuropathol 1982, 57:239-242.
    • (1982) Acta Neuropathol , vol.57 , pp. 239-242
    • Eikelenboom, P.1    Stam, F.C.2
  • 8
    • 0018348757 scopus 로고
    • Fractionation and structural elucidation of the active components of aurintricarboxylic acid, a potent inhibitor of protein nucleic acid interactions
    • González R.G., Blackburn B.J., Schleich T. Fractionation and structural elucidation of the active components of aurintricarboxylic acid, a potent inhibitor of protein nucleic acid interactions. Biochim. Biophys. Acta 1979, 562:534-545.
    • (1979) Biochim. Biophys. Acta , vol.562 , pp. 534-545
    • González, R.G.1    Blackburn, B.J.2    Schleich, T.3
  • 9
    • 84864388858 scopus 로고
    • Ammonium salt of aurin tricarboxylic acid
    • Heisig G.B., Lauer M. Ammonium salt of aurin tricarboxylic acid. Org. Synth 1941, 1:54.
    • (1941) Org. Synth , vol.1 , pp. 54
    • Heisig, G.B.1    Lauer, M.2
  • 12
    • 0028924871 scopus 로고
    • Chimeras of human complement C9 reveal the site recognized by complement regulatory protein CD59
    • Hüsler T., Lockert D.H., Kaufman K.M., Sodetz J.M., Sims P.J. Chimeras of human complement C9 reveal the site recognized by complement regulatory protein CD59. J. Biol. Chem 1995, 270:3483-3486.
    • (1995) J. Biol. Chem , vol.270 , pp. 3483-3486
    • Hüsler, T.1    Lockert, D.H.2    Kaufman, K.M.3    Sodetz, J.M.4    Sims, P.J.5
  • 13
    • 0027432431 scopus 로고
    • Neuronal beta-amyloid precursor protein gene expression: regulation by aurintricarboxylic acid
    • Joseph R., Tsang W., Han E., Saed G.M. Neuronal beta-amyloid precursor protein gene expression: regulation by aurintricarboxylic acid. Brain Res 1993, 625:244-255.
    • (1993) Brain Res , vol.625 , pp. 244-255
    • Joseph, R.1    Tsang, W.2    Han, E.3    Saed, G.M.4
  • 14
    • 0026605961 scopus 로고
    • Immunologic reactions in amyotrophic lateral sclerosis
    • Kawamata T., Akiyama H., Yamada T., McGeer P.L. Immunologic reactions in amyotrophic lateral sclerosis. Am. J. Pathol 1992, 140:697-707.
    • (1992) Am. J. Pathol , vol.140 , pp. 697-707
    • Kawamata, T.1    Akiyama, H.2    Yamada, T.3    McGeer, P.L.4
  • 15
    • 0031927160 scopus 로고    scopus 로고
    • Nonsense mutation in exon 4 of human complement C9 gene is the major cause of Japanese complement C9 deficiency
    • Kira R., Ihara K., Takada H., Gondo K., Hara T. Nonsense mutation in exon 4 of human complement C9 gene is the major cause of Japanese complement C9 deficiency. Hum. Genet 1998, 102:605-610.
    • (1998) Hum. Genet , vol.102 , pp. 605-610
    • Kira, R.1    Ihara, K.2    Takada, H.3    Gondo, K.4    Hara, T.5
  • 17
    • 78349279184 scopus 로고    scopus 로고
    • Astrocytes are GABAergic cells that modulate microglial activity
    • Lee M., Schwab C., McGeer P.L. Astrocytes are GABAergic cells that modulate microglial activity. Glia 2011, 59:152-165.
    • (2011) Glia , vol.59 , pp. 152-165
    • Lee, M.1    Schwab, C.2    McGeer, P.L.3
  • 18
    • 0031967214 scopus 로고    scopus 로고
    • Multiple inhibition of platelet activation by aurintricarboxylic acid prevents vascular stenosis after endothelial injury in hamster carotid artery
    • Matsuno H., Kozawa O., Niwa M., Tanabe K., Ichimaru K., Takiguchi Y., Yokota M., Hayashi H., Uematsu T. Multiple inhibition of platelet activation by aurintricarboxylic acid prevents vascular stenosis after endothelial injury in hamster carotid artery. Thromb. Haemost 1998, 79:865-871.
    • (1998) Thromb. Haemost , vol.79 , pp. 865-871
    • Matsuno, H.1    Kozawa, O.2    Niwa, M.3    Tanabe, K.4    Ichimaru, K.5    Takiguchi, Y.6    Yokota, M.7    Hayashi, H.8    Uematsu, T.9
  • 19
    • 0024317005 scopus 로고
    • Activation of the classical complement pathway in brain tissue of Alzheimer patients
    • McGeer P.L., Akiyama H., Itagaki S., McGeer E.G. Activation of the classical complement pathway in brain tissue of Alzheimer patients. Neurosci. Lett 1989, 107:341-346.
    • (1989) Neurosci. Lett , vol.107 , pp. 341-346
    • McGeer, P.L.1    Akiyama, H.2    Itagaki, S.3    McGeer, E.G.4
  • 20
    • 0037405981 scopus 로고    scopus 로고
    • Is there a future for vaccination as a treatment for Alzheimer's disease?
    • McGeer P.L., McGeer E. Is there a future for vaccination as a treatment for Alzheimer's disease?. Neurobiol. Aging 2003, 24:391-395.
    • (2003) Neurobiol. Aging , vol.24 , pp. 391-395
    • McGeer, P.L.1    McGeer, E.2
  • 21
    • 14944352071 scopus 로고    scopus 로고
    • Inflammation and the degenerative diseases of aging
    • McGeer P.L., McGeer E.G. Inflammation and the degenerative diseases of aging. Ann. N. Y. Acad. Sci 2004, 1035:104-116.
    • (2004) Ann. N. Y. Acad. Sci , vol.1035 , pp. 104-116
    • McGeer, P.L.1    McGeer, E.G.2
  • 22
    • 75149130667 scopus 로고    scopus 로고
    • Type 2 diabetes: local inflammation and direct effect of bacterial toxic components
    • Miklossy J., Martins L., Darbinian N., Khalili K., McGeer P.L. Type 2 diabetes: local inflammation and direct effect of bacterial toxic components. The Open Path. J 2008, 2:86-95.
    • (2008) The Open Path. J , vol.2 , pp. 86-95
    • Miklossy, J.1    Martins, L.2    Darbinian, N.3    Khalili, K.4    McGeer, P.L.5
  • 23
    • 0029055738 scopus 로고
    • Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein
    • Moran P.M., Higgins L.S., Cordell B., Moser P.C. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:5341-5345.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 5341-5345
    • Moran, P.M.1    Higgins, L.S.2    Cordell, B.3    Moser, P.C.4
  • 24
    • 0037108593 scopus 로고    scopus 로고
    • Membrane attack complex contributes to destruction of vascular integrity in acute lung allograft rejection
    • Nakashima S., Qian Z., Rahimi S., Wasowska B.A., Baldwin W.M. Membrane attack complex contributes to destruction of vascular integrity in acute lung allograft rejection. J. Immunol 2002, 169:4620-4627.
    • (2002) J. Immunol , vol.169 , pp. 4620-4627
    • Nakashima, S.1    Qian, Z.2    Rahimi, S.3    Wasowska, B.A.4    Baldwin, W.M.5
  • 25
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report
    • Nicoll J.A., Wilkinson D., Holmes C., Steart P., Markham H., Weller R.O. Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat. Med 2003, 9:448-452.
    • (2003) Nat. Med , vol.9 , pp. 448-452
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 26
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal beta amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
    • Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., Guillozet-Bongaarts A., Ohno M., Disterhoft J., Van Eldik L., Berry R., Vassar R. Intraneuronal beta amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci 2006, 26:10129-10140.
    • (2006) J. Neurosci , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van Eldik, L.10    Berry, R.11    Vassar, R.12
  • 28
    • 0029917899 scopus 로고    scopus 로고
    • Aurin tricarboxylic acid inhibits adhesion of platelets to subendothelium
    • Owens M.R., Holme S. Aurin tricarboxylic acid inhibits adhesion of platelets to subendothelium. Thromb. Res 1996, 81:177-185.
    • (1996) Thromb. Res , vol.81 , pp. 177-185
    • Owens, M.R.1    Holme, S.2
  • 29
    • 33846913468 scopus 로고    scopus 로고
    • Prevalence of mutations leading to complete C6 deficiency (C6Q0) in the Western Cape, South Africa and detection of novel mutations leading to C6Q0 in an Irish family
    • Parham K.L., Roberts A., Thomas A., Würzner R., Henderson H.E., Potter P.C., Morgan B.P., Orren A. Prevalence of mutations leading to complete C6 deficiency (C6Q0) in the Western Cape, South Africa and detection of novel mutations leading to C6Q0 in an Irish family. Mol. Immunol 2007, 44:2756-2760.
    • (2007) Mol. Immunol , vol.44 , pp. 2756-2760
    • Parham, K.L.1    Roberts, A.2    Thomas, A.3    Würzner, R.4    Henderson, H.E.5    Potter, P.C.6    Morgan, B.P.7    Orren, A.8
  • 31
    • 0029589516 scopus 로고
    • Ultrastructure of excitotoxic neuronal death in murine cortical culture
    • Regan R.F., Panter S.S., Witz A., Tilly J.L., Giffard R.G. Ultrastructure of excitotoxic neuronal death in murine cortical culture. Brain Res 1995, 705:188-198.
    • (1995) Brain Res , vol.705 , pp. 188-198
    • Regan, R.F.1    Panter, S.S.2    Witz, A.3    Tilly, J.L.4    Giffard, R.G.5
  • 32
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • Ricklin D., Hajishengallis G., Yang K., Lambris J.D. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol 2010, 11:785-797.
    • (2010) Nat. Immunol , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 36
    • 2942611429 scopus 로고    scopus 로고
    • Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease
    • Schwab C., Hosokawa M., McGeer P.L. Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease. Exp. Neurol 2004, 182:52-64.
    • (2004) Exp. Neurol , vol.182 , pp. 52-64
    • Schwab, C.1    Hosokawa, M.2    McGeer, P.L.3
  • 37
    • 0030020028 scopus 로고    scopus 로고
    • Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins
    • Schwab C., Steele J.C., McGeer P.L. Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins. Brain Res 1996, 707:196-205.
    • (1996) Brain Res , vol.707 , pp. 196-205
    • Schwab, C.1    Steele, J.C.2    McGeer, P.L.3
  • 39
    • 0027310539 scopus 로고
    • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria
    • Takeda J., Miyata T., Kawagoe K., Iida Y., Endo Y., Fujita T., Takahashi M., Kitani T., Kinoshita T. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 1993, 73:703-711.
    • (1993) Cell , vol.73 , pp. 703-711
    • Takeda, J.1    Miyata, T.2    Kawagoe, K.3    Iida, Y.4    Endo, Y.5    Fujita, T.6    Takahashi, M.7    Kitani, T.8    Kinoshita, T.9
  • 41
    • 0026725485 scopus 로고
    • Isolation and structural elucidation of low molecular weight components of aurintricarboxylic acid (ATA)
    • Wang P., Kozlowski J., Cushman M. Isolation and structural elucidation of low molecular weight components of aurintricarboxylic acid (ATA). J. Org. Chem 1992, 57:3861-3866.
    • (1992) J. Org. Chem , vol.57 , pp. 3861-3866
    • Wang, P.1    Kozlowski, J.2    Cushman, M.3
  • 43
    • 0041845119 scopus 로고    scopus 로고
    • Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats
    • Wu G., Korsgren O., Sun S., Van Rooijen N., Tibell A. Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats. Xenotransplantation 2003, 10:214-222.
    • (2003) Xenotransplantation , vol.10 , pp. 214-222
    • Wu, G.1    Korsgren, O.2    Sun, S.3    Van Rooijen, N.4    Tibell, A.5
  • 45
    • 0026680616 scopus 로고
    • Lewy bodies in Parkinson's disease are recognized by antibodies to complement proteins
    • Yamada T., McGeer P.L., McGeer E.G. Lewy bodies in Parkinson's disease are recognized by antibodies to complement proteins. Acta Neuropathol 1992, 84:101-104.
    • (1992) Acta Neuropathol , vol.84 , pp. 101-104
    • Yamada, T.1    McGeer, P.L.2    McGeer, E.G.3
  • 47
    • 0035099170 scopus 로고    scopus 로고
    • Generation of C-reactive protein and complement components in atherosclerotic plaques
    • Yasojima K., Schwab C., McGeer E.G., McGeer P.L. Generation of C-reactive protein and complement components in atherosclerotic plaques. Am. J. Pathol 2001, 158:1039-1051.
    • (2001) Am. J. Pathol , vol.158 , pp. 1039-1051
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 48
    • 84864389085 scopus 로고
    • Expression of the membrane attack complex in Pick disease brain
    • Yasuhara O., Aimy Y., McGeer E.G., McGeer P.L. Expression of the membrane attack complex in Pick disease brain. Brain Res 1994, 654:346-349.
    • (1994) Brain Res , vol.654 , pp. 346-349
    • Yasuhara, O.1    Aimy, Y.2    McGeer, E.G.3    McGeer, P.L.4
  • 49
    • 0031881824 scopus 로고    scopus 로고
    • Molecular defects leading to human complement component C6 deficiency in an African-American family
    • Zhu Z.B., Totemchokchyakarn K., Atkinson T.P., Volanakis J.E. Molecular defects leading to human complement component C6 deficiency in an African-American family. Clin. Exp. Immunol 1998, 111:91-96.
    • (1998) Clin. Exp. Immunol , vol.111 , pp. 91-96
    • Zhu, Z.B.1    Totemchokchyakarn, K.2    Atkinson, T.P.3    Volanakis, J.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.