Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells

Journal of Agricultural and Food Chemistry

Volumn 66, Issue 38, 2018, Pages 9960-9967

  Choi, Jhin Baek ^a   Kim, Ju Ha ^a   Lee, Hyemin ^a   Pak, Ji Na ^b   Shim, Bum Sang ^a   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

^b Graduate School of East West Medical Science   (South Korea)

Author keywords

apoptosis; Kaempferol; p38 MAPK; p53; ROS

Indexed keywords

CELL DEATH; CHEMICAL ACTIVATION; CYTOTOXICITY; DISEASES; OXYGEN; PHOSPHORYLATION;

ANTI-PROLIFERATIVE; CASPASE ACTIVATION; COLORECTAL CANCER CELL; INDUCED APOPTOSIS; KAEMPFEROL; MOLECULAR MECHANISM; P38 MAPK; REACTIVE OXYGEN SPECIES;

FLAVONOIDS;

CASPASE; KAEMPFEROL; KAEMPFEROL DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; CELL CYCLE; COLORECTAL TUMOR; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

APOPTOSIS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; HUMANS; KAEMPFEROLS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 85053535745     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.8b02656     Document Type: Article

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