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Volumn 30, Issue 4, 2009, Pages 655-661

Decursin and decursinol angelate inhibit VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

ANGELICA GIGAS EXTRACT; DECURSIN; DECURSINOL ANGELATE; MITOGEN ACTIVATED PROTEIN KINASE; PYRANOCOUMARIN DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 64349105855     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp039     Document Type: Article
Times cited : (82)

References (43)
  • 1
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman,J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl Cancer Inst., 82, 4-6.
    • (1990) J. Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 2
    • 0028114985 scopus 로고
    • The implications of angiogenesis for the biology and therapy of cancer metastasis
    • Fidler,I.J. et al. (1994) The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell, 79, 185-188.
    • (1994) Cell , vol.79 , pp. 185-188
    • Fidler, I.J.1
  • 3
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan,D. et al. (2000) The hallmarks of cancer. Cell, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1
  • 4
    • 0017171175 scopus 로고
    • Prolonged tumor dormancy by prevention of neovascularization in the vitreous
    • Brem,S. et al. (1976) Prolonged tumor dormancy by prevention of neovascularization in the vitreous. Cancer Res., 36, 2807-2812.
    • (1976) Cancer Res , vol.36 , pp. 2807-2812
    • Brem, S.1
  • 5
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren,L. et al. (1995) Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat. Med., 1, 117-118.
    • (1995) Nat. Med , vol.1 , pp. 117-118
    • Holmgren, L.1
  • 6
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman,J. (1971) Tumor angiogenesis: Therapeutic implications. N. Engl. J. Med., 285, 1182-1186.
    • (1971) N. Engl. J. Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 7
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • Shaheen,R.M. et al. (1999) Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res., 59, 5412-5416.
    • (1999) Cancer Res , vol.59 , pp. 5412-5416
    • Shaheen, R.M.1
  • 8
    • 0032758072 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) family members in breast cancer
    • Kurebayashi,J. et al. (1999) Expression of vascular endothelial growth factor (VEGF) family members in breast cancer. Jpn. J. Cancer Res., 90, 977-981.
    • (1999) Jpn. J. Cancer Res , vol.90 , pp. 977-981
    • Kurebayashi, J.1
  • 9
    • 0032714311 scopus 로고    scopus 로고
    • KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in murine hepatocellular carcinoma cells
    • Yoshiji,H. et al. (1999) KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in murine hepatocellular carcinoma cells. Hepatology, 30, 1179-1186.
    • (1999) Hepatology , vol.30 , pp. 1179-1186
    • Yoshiji, H.1
  • 10
    • 18744419749 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer
    • Droller,M.J. (1998) Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer. J. Urol. 160, 1932.
    • (1998) J. Urol , vol.160 , pp. 1932
    • Droller, M.J.1
  • 11
    • 0031695228 scopus 로고    scopus 로고
    • Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients
    • Kitamura,M. et al. (1998) Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients. Oncol. Rep., 5, 1419-1424.
    • (1998) Oncol. Rep , vol.5 , pp. 1419-1424
    • Kitamura, M.1
  • 12
    • 0032903649 scopus 로고    scopus 로고
    • Highly metastatic human prostate cancer growing within the prostate of athymic mice overexpresses vascular endothelial growth factor
    • Balbay,M.D. et al. (1999) Highly metastatic human prostate cancer growing within the prostate of athymic mice overexpresses vascular endothelial growth factor. Clin. Cancer Res., 5, 783-789.
    • (1999) Clin. Cancer Res , vol.5 , pp. 783-789
    • Balbay, M.D.1
  • 13
    • 0034000699 scopus 로고    scopus 로고
    • VEGF receptor signaling in tumor angiogenesis
    • McMahon,G. (2000) VEGF receptor signaling in tumor angiogenesis. Oncologist, 5, 3-10.
    • (2000) Oncologist , vol.5 , pp. 3-10
    • McMahon, G.1
  • 14
    • 0037826769 scopus 로고
    • Studies on the components of Umbelliferae plants in Korea: Pharmacological study of decursin, decursinol and nodakenin
    • Chi,H.J. et al. (1970) Studies on the components of Umbelliferae plants in Korea: Pharmacological study of decursin, decursinol and nodakenin. Korean J. Pharmacol., 1, 25-32.
    • (1970) Korean J. Pharmacol , vol.1 , pp. 25-32
    • Chi, H.J.1
  • 15
    • 12944306438 scopus 로고    scopus 로고
    • Antitumor activity of decursinol angelate and decursin from Angelica gigas
    • Lee,S. et al. (2003) Antitumor activity of decursinol angelate and decursin from Angelica gigas. Arch. Pharm. Res., 26, 727-730.
    • (2003) Arch. Pharm. Res , vol.26 , pp. 727-730
    • Lee, S.1
  • 16
    • 0036342882 scopus 로고    scopus 로고
    • Coumarins and pyrimidine from Angelica gigas roots
    • Lee,S. et al. (2002) Coumarins and pyrimidine from Angelica gigas roots. Nat. Prod. Sci., 8, 58-61.
    • (2002) Nat. Prod. Sci , vol.8 , pp. 58-61
    • Lee, S.1
  • 17
    • 0014293960 scopus 로고
    • Coumarins from the root of Angelica gigas Nakai
    • Konoshima,M. et al. (1968) Coumarins from the root of Angelica gigas Nakai. Chem. Pharm. Bull., 16, 1139-1140.
    • (1968) Chem. Pharm. Bull , vol.16 , pp. 1139-1140
    • Konoshima, M.1
  • 18
    • 0037226826 scopus 로고    scopus 로고
    • Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice
    • Kang,S.Y. et al. (2003) Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice. Neurobiol. Learn. Mem., 79, 11-18.
    • (2003) Neurobiol. Learn. Mem , vol.79 , pp. 11-18
    • Kang, S.Y.1
  • 19
    • 34247349616 scopus 로고    scopus 로고
    • Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice
    • Kim,D.H. et al. (2007) Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice. Life Sci., 80 1944-1950.
    • (2007) Life Sci , vol.80 , pp. 1944-1950
    • Kim, D.H.1
  • 20
    • 19344368158 scopus 로고    scopus 로고
    • Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells
    • Kim,H.H. et al. (2005) Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells. Cancer Lett., 223, 191-201.
    • (2005) Cancer Lett , vol.223 , pp. 191-201
    • Kim, H.H.1
  • 21
    • 40449133797 scopus 로고    scopus 로고
    • Low energy proton beam induces tumor cell apoptosis through reactive oxygen species and activation of caspases
    • Lee,K.B. et al. (2008) Low energy proton beam induces tumor cell apoptosis through reactive oxygen species and activation of caspases. Exp. Mol. Med., 29, 118-129.
    • (2008) Exp. Mol. Med , vol.29 , pp. 118-129
    • Lee, K.B.1
  • 23
    • 13444283311 scopus 로고    scopus 로고
    • A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells
    • Yim,D.S. et al. (2005) A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. Cancer Res., 65, 1035-1043.
    • (2005) Cancer Res , vol.65 , pp. 1035-1043
    • Yim, D.S.1
  • 24
    • 33845666847 scopus 로고    scopus 로고
    • The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia
    • Kilic,E. et al. (2006) The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J., 20, 1185-1187.
    • (2006) FASEB J , vol.20 , pp. 1185-1187
    • Kilic, E.1
  • 25
    • 4143127785 scopus 로고    scopus 로고
    • Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: The role of ERK1/2, PI3K, and matrix metalloproteinases
    • Yao,J.S. et al. (2004) Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: The role of ERK1/2, PI3K, and matrix metalloproteinases. Circ. Res., 95, 364-371.
    • (2004) Circ. Res , vol.95 , pp. 364-371
    • Yao, J.S.1
  • 26
    • 16644395747 scopus 로고    scopus 로고
    • The role of VEGF in the regulation of physiological and pathological angiogenesis
    • Ferrara,N. (2005) The role of VEGF in the regulation of physiological and pathological angiogenesis. EXS, 94, 209-231.
    • (2005) EXS , vol.94 , pp. 209-231
    • Ferrara, N.1
  • 27
    • 0035003384 scopus 로고    scopus 로고
    • Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
    • Shibuya,M. (2001) Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct. Funct., 26, 25-35.
    • (2001) Cell Struct. Funct , vol.26 , pp. 25-35
    • Shibuya, M.1
  • 28
    • 0033047875 scopus 로고    scopus 로고
    • VEGFs, receptors and angiogenesis
    • Veikkola,T. et al. (1999) VEGFs, receptors and angiogenesis. Semin. Cancer Biol., 9, 211-220.
    • (1999) Semin. Cancer Biol , vol.9 , pp. 211-220
    • Veikkola, T.1
  • 29
    • 31744449858 scopus 로고    scopus 로고
    • Development of angiogenesis inhibitors to vascular endothelial growth factor receptor 2. Current status and future perspective
    • Paz,K. et al. (2005) Development of angiogenesis inhibitors to vascular endothelial growth factor receptor 2. Current status and future perspective. Front. Biosci., 10, 1415-1439.
    • (2005) Front. Biosci , vol.10 , pp. 1415-1439
    • Paz, K.1
  • 30
    • 0036279804 scopus 로고    scopus 로고
    • Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics
    • Zhu,Z. et al. (2002) Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics. Curr. Cancer Drug Targets, 2, 135-156.
    • (2002) Curr. Cancer Drug Targets , vol.2 , pp. 135-156
    • Zhu, Z.1
  • 31
    • 0035336732 scopus 로고    scopus 로고
    • Monoclonal antibody strategies to block angiogenesis
    • Hicklin,D.J. et al. (2001) Monoclonal antibody strategies to block angiogenesis. Drug Discov. Today, 6, 517-528.
    • (2001) Drug Discov. Today , vol.6 , pp. 517-528
    • Hicklin, D.J.1
  • 32
    • 0035966004 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induction of the angiogenic phenotype require Ras activation
    • Meadows,K.N. et al. (2001) Vascular endothelial growth factor induction of the angiogenic phenotype require Ras activation. J. Biol. Chem., 276, 49289-49298.
    • (2001) J. Biol. Chem , vol.276 , pp. 49289-49298
    • Meadows, K.N.1
  • 33
    • 0035870129 scopus 로고    scopus 로고
    • c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells
    • Minet,E. et al. (2001) c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells. Exp. Cell Res., 265, 114-124.
    • (2001) Exp. Cell Res , vol.265 , pp. 114-124
    • Minet, E.1
  • 34
    • 0034027920 scopus 로고    scopus 로고
    • Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors
    • Hanemaaijer,R. et al. (2000) Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors. Int. J. Cancer, 86, 204-207.
    • (2000) Int. J. Cancer , vol.86 , pp. 204-207
    • Hanemaaijer, R.1
  • 35
    • 33645532055 scopus 로고    scopus 로고
    • Activation of stat3 in human melanoma promotes brain metastasis
    • Xie,T.X. et al. (2006) Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res., 66, 3188-3195.
    • (2006) Cancer Res , vol.66 , pp. 3188-3195
    • Xie, T.X.1
  • 36
    • 0037449202 scopus 로고    scopus 로고
    • Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells: Down-regulation of matrix metalloproteinase-3/-9/-14 and CD44
    • Tanimura,S. et al. (2003) Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells: Down-regulation of matrix metalloproteinase-3/-9/-14 and CD44. Biochem. Biophys. Res. Commun. 304, 801-806.
    • (2003) Biochem. Biophys. Res. Commun , vol.304 , pp. 801-806
    • Tanimura, S.1
  • 37
    • 0037103912 scopus 로고    scopus 로고
    • Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro
    • Lakka,S.S. et al. (2002) Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro. Oncogene, 21, 5601-5608.
    • (2002) Oncogene , vol.21 , pp. 5601-5608
    • Lakka, S.S.1
  • 38
    • 33646357488 scopus 로고    scopus 로고
    • Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway
    • Kuo,L. et al. (2006) Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway. J. Cell. Physiol., 207, 729-734.
    • (2006) J. Cell. Physiol , vol.207 , pp. 729-734
    • Kuo, L.1
  • 39
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara,N. et al. (2004) Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat. Rev. Drug Discov., 3, 391-400.
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1
  • 40
    • 0034853191 scopus 로고    scopus 로고
    • Comparative studies on concentration of decursinol in plasma after oral administration of Angelicae gigantis radix extract and combined use of decursin and Cnidii rhizoma extract or Bupleuri radix extract in rats
    • Park,R.J. et al. (2001) Comparative studies on concentration of decursinol in plasma after oral administration of Angelicae gigantis radix extract and combined use of decursin and Cnidii rhizoma extract or Bupleuri radix extract in rats. Korean J. Pharmacogn., 32, 72-78.
    • (2001) Korean J. Pharmacogn , vol.32 , pp. 72-78
    • Park, R.J.1
  • 41
    • 40349114562 scopus 로고    scopus 로고
    • Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells
    • Jiang,C. et al. (2007) Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells. Breast Cancer Res., 9, R77.
    • (2007) Breast Cancer Res , vol.9
    • Jiang, C.1
  • 42
    • 34147131853 scopus 로고    scopus 로고
    • A novel class of pyranocoumarin anti-androgen receptor signaling compounds
    • Guo,J. et al. (2007) A novel class of pyranocoumarin anti-androgen receptor signaling compounds. Mol. Cancer Ther., 6, 907-917.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 907-917
    • Guo, J.1
  • 43
    • 31544472904 scopus 로고    scopus 로고
    • Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: Identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer
    • Jiang,C. et al. (2006) Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. Cancer Res., 66, 453-463.
    • (2006) Cancer Res , vol.66 , pp. 453-463
    • Jiang, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.