Role of reactive oxygen species-mediated MAPK and NF-κB activation in polygonatum cyrtonema lectin-induced apoptosis and autophagy in human lung adenocarcinoma A549 cells

Journal of Biochemistry

Volumn 160, Issue 6, 2016, Pages 315-324

  Liu, Tao ^a   Wu, Lei ^a   Wang, Di ^a   Wang, Haiyang ^a   Chen, Jinwu ^a,b   Yang, Chunlan ^a   Bao, Jinku ^a,c   Wu, Chuanfang ^a,c  

^a SICHUAN UNIVERSITY   (China)

^b HEFEI NORMAL UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; MAPK; NF B; Polygonatum cyrtonema lectin

Indexed keywords

ACETYLCYSTEINE; BECLIN 1; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT LECTIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; SEQUESTOSOME 1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR;

A-549 CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL SURFACE; CELL SURVIVAL; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INTERNALIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; POLYGONATUM; POLYGONATUM CYRTONEMA; PROTEIN FUNCTION; PROTEIN INDUCTION; RHIZOME; SIGNAL TRANSDUCTION; ADENOCARCINOMA; CHEMISTRY; DRUG EFFECTS; LUNG TUMOR; METABOLISM; TUMOR CELL LINE;

ADENOCARCINOMA; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; PLANT LECTINS; POLYGONATUM; REACTIVE OXYGEN SPECIES;

EID: 85014574355     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvw040     Document Type: Article

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