Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis

Cell

Volumn 174, Issue 6, 2018, Pages 1549-1558.e14

  Yu, Tao ^a   Zhou, Yongjin J ^a,c   Huang, Mingtao ^a   Liu, Quanli ^a   Pereira, Rui ^a   David, Florian ^a   Nielsen, Jens ^a,b  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b Chalmers University of Technology   (Denmark)

^c DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

adaptive laboratory evolution; Crabtree effect; fatty acids; lipid; metabolic engineering; metabolism; synthetic biology

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALCOHOL; CARBON; FATTY ACID; PYRUVATE DECARBOXYLASE; PYRUVATE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ACETYL COENZYME A; GLUCOSE; ISOCITRATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; BIOMASS; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; FATTY ACID SYNTHESIS; GENE DELETION; GENE SEQUENCE; LIPOGENESIS; METABOLIC ENGINEERING; MUTATION; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PRIORITY JOURNAL; PROCESS DESIGN; SACCHAROMYCES CEREVISIAE; YEAST; BIOSYNTHESIS; GENETICS; GLYCOLYSIS; METABOLISM; PENTOSE PHOSPHATE CYCLE;

ACETYL COENZYME A; FATTY ACIDS, NONESTERIFIED; GLUCOSE; GLYCOLYSIS; ISOCITRATE DEHYDROGENASE; LIPOGENESIS; METABOLIC ENGINEERING; NADP; PENTOSE PHOSPHATE PATHWAY; PYRUVATE KINASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 85052830675     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.07.013     Document Type: Article

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