An engineered Aro1 protein degradation approach for increased cis,cis-muconic acid biosynthesis in Saccharomyces cerevisiae

Applied and Environmental Microbiology

Volumn 84, Issue 17, 2018, Pages

  Pyne, Michael E ^a,b   Narcross, Lauren ^a,b   Melgar, Mindy ^a,b   Kevvai, Kaspar ^a,b   Mookerjee, Shoham ^a,b,c   Leite, Gustavo B ^a,b,d   Martin, Vincent J J ^a,b  

^a Dept of Electrical and Computer Engineering   (Canada)

^b and Centre for Structural and Functional Genomics   (Canada)

^c Hyasynth Bio   (Canada)

^d Universite Sainte Anne   (Canada)

Author keywords

Adipic acid; Aro1; Degron tagging; Metabolic engineering; Muconic acid; Saccharomyces cerevisiae; Shikimate

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; DEHALOGENATION; ENZYME ACTIVITY; METABOLIC ENGINEERING; PLASTIC BOTTLES;

ADIPIC ACIDS; ARO1; DEGRON TAGGING; MUCONIC ACID; SHIKIMATES;

YEAST;

AMINO ACID; BIOENGINEERING; BIOREACTOR; DEGRADATION; ORGANIC ACID; PROTEIN; YEAST;

SACCHAROMYCES CEREVISIAE;

ADIPIC ACID; ADIPIC ACID DERIVATIVE; CARBOXYLYASE; MUCONIC ACID; PHENYLACRYLIC ACID DECARBOXYLASE; PHTHALIC ACID DERIVATIVE; SHIKIMIC ACID; SORBIC ACID; TEREPHTHALIC ACID;

BIOREACTOR; GENETICS; METABOLIC ENGINEERING; METABOLISM; MICROBIOLOGY; PROCEDURES; PROTEIN DEGRADATION; SACCHAROMYCES CEREVISIAE;

ADIPATES; BIOREACTORS; CARBOXY-LYASES; METABOLIC ENGINEERING; PHTHALIC ACIDS; PROTEOLYSIS; SACCHAROMYCES CEREVISIAE; SHIKIMIC ACID; SORBIC ACID;

EID: 85052555327     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01095-18     Document Type: Article

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