IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization

Nature Cell Biology

Volumn 20, Issue 9, 2018, Pages 1084-1097

  Castaño, Zafira ^a,b   San Juan, Beatriz P ^c   Spiegel, Asaf ^d   Pant, Ayush ^d   DeCristo, Molly J ^a,b   Laszewski, Tyler ^a   Ubellacker, Jessalyn M ^a,b   Janssen, Susanne R ^d   Dongre, Anushka ^d   Reinhardt, Ferenc ^d   Henderson, Ayana ^a,b   del Rio, Ana Garcia ^a   Gifford, Ann M ^d   Herbert, Zachary T ^e   Hutchinson, John N ^f   Weinberg, Robert A ^d,g   Chaffer, Christine L ^c,d   McAllister, Sandra S ^a,b,h,i  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^h BROAD INSTITUTE OF MIT AND HARVARD   (United States)

ⁱ HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; UVOMORULIN; ANTIINFLAMMATORY AGENT; CADHERIN; CDH1 PROTEIN, HUMAN; IL1B PROTEIN, HUMAN; IL1B PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; TRANSCRIPTION FACTOR ZEB1; ZEB1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER SURVIVAL; CELL CULTURE; CELL DIFFERENTIATION; CELL PLASTICITY; CONTROLLED STUDY; DISTANT METASTASIS FREE SURVIVAL; FEMALE; GENE; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INFLAMMATION; INNATE IMMUNITY; METASTASIS; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT; ZEB1 GENE; ANIMAL; BONE MARROW CELL; BREAST TUMOR; CELL COMMUNICATION; CELL PROLIFERATION; DRUG EFFECT; DRUG SCREENING; GENETICS; IMMUNOLOGY; LUNG TUMOR; LYMPH NODE METASTASIS; METABOLISM; NUDE MOUSE; PATHOLOGY; SECONDARY; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR CELL LINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD; BREAST NEOPLASMS; CADHERINS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PLASTICITY; CELL PROLIFERATION; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MICE, NUDE; MYELOID CELLS; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS; ZINC FINGER E-BOX-BINDING HOMEOBOX 1;

EID: 85052376277     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/s41556-018-0173-5     Document Type: Article

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