-
1
-
-
84976539958
-
Emt: 2016
-
Nieto MA, Huang RY, Jackson RA, Thiery JP (2016) Emt: 2016. Cell 166(1):21-45.
-
(2016)
Cell
, vol.166
, Issue.1
, pp. 21-45
-
-
Nieto, M.A.1
Huang, R.Y.2
Jackson, R.A.3
Thiery, J.P.4
-
2
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
Peinado H, Olmeda D, Cano A (2007) Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat Rev Cancer 7(6):415-428.
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.6
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
3
-
-
33646384428
-
Fibroblasts in cancer
-
Kalluri R, Zeisberg M (2006) Fibroblasts in cancer. Nat Rev Cancer 6(5):392-401.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.5
, pp. 392-401
-
-
Kalluri, R.1
Zeisberg, M.2
-
4
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100(7): 3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
5
-
-
84903768676
-
Tackling the cancer stem cells: What challenges do they pose?
-
Pattabiraman DR, Weinberg RA (2014) Tackling the cancer stem cells: What challenges do they pose? Nat Rev Drug Discov 13(7):497-512.
-
(2014)
Nat Rev Drug Discov
, vol.13
, Issue.7
, pp. 497-512
-
-
Pattabiraman, D.R.1
Weinberg, R.A.2
-
6
-
-
84894593599
-
Molecular mechanisms of epithelial-mesenchymal transition
-
Lamouille S, Xu J, Derynck R (2014) Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15(3):178-196.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, Issue.3
, pp. 178-196
-
-
Lamouille, S.1
Xu, J.2
Derynck, R.3
-
7
-
-
84906987240
-
Surprisal analysis characterizes the free energy time course of cancer cells undergoing epithelial-tomesenchymal transition
-
Zadran S, Arumugam R, Herschman H, Phelps ME, Levine RD (2014) Surprisal analysis characterizes the free energy time course of cancer cells undergoing epithelial-tomesenchymal transition. Proc Natl Acad Sci USA 111(36):13235-13240.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.36
, pp. 13235-13240
-
-
Zadran, S.1
Arumugam, R.2
Herschman, H.3
Phelps, M.E.4
Levine, R.D.5
-
8
-
-
33645302628
-
The epithelial-mesenchymal transition: New insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R, Thompson EW (2006) The epithelial-mesenchymal transition: New insights in signaling, development, and disease. J Cell Biol 172(7):973-981.
-
(2006)
J Cell Biol
, vol.172
, Issue.7
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
9
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133(4):704-715.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
-
10
-
-
84876489727
-
Cancer stem cells: The challenges ahead
-
Medema JP (2013) Cancer stem cells: The challenges ahead. Nat Cell Biol 15(4): 338-344.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.4
, pp. 338-344
-
-
Medema, J.P.1
-
12
-
-
34247569300
-
Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2- negative invasive breast cancer, the so-called triple-negative phenotype: A population- based study from the California cancer Registry
-
Bauer KR, Brown M, Cress RD, Parise CA, Caggiano V (2007) Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2- negative invasive breast cancer, the so-called triple-negative phenotype: A population- based study from the California cancer Registry. Cancer 109(9):1721-1728.
-
(2007)
Cancer
, vol.109
, Issue.9
, pp. 1721-1728
-
-
Bauer, K.R.1
Brown, M.2
Cress, R.D.3
Parise, C.A.4
Caggiano, V.5
-
13
-
-
84940399348
-
Clinical significance of the integrin α6β4 in human malignancies
-
Stewart RL, O'Connor KL (2015) Clinical significance of the integrin α6β4 in human malignancies. Lab Invest 95(9):976-986.
-
(2015)
Lab Invest
, vol.95
, Issue.9
, pp. 976-986
-
-
Stewart, R.L.1
O'Connor, K.L.2
-
14
-
-
84962396691
-
An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAKAKT pathway
-
Leng C, et al. (2016) An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAKAKT pathway. Cancer Lett 376(1):188-196.
-
(2016)
Cancer Lett
, vol.376
, Issue.1
, pp. 188-196
-
-
Leng, C.1
-
15
-
-
33845697707
-
Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth
-
Bertotti A, Comoglio PM, Trusolino L (2006) Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth. J Cell Biol 175(6):993-1003.
-
(2006)
J Cell Biol
, vol.175
, Issue.6
, pp. 993-1003
-
-
Bertotti, A.1
Comoglio, P.M.2
Trusolino, L.3
-
16
-
-
39749084606
-
Analysis of integrin beta4 expression in human breast cancer: Association with basal-like tumors and prognostic significance
-
Lu S, Simin K, Khan A, Mercurio AM (2008) Analysis of integrin beta4 expression in human breast cancer: Association with basal-like tumors and prognostic significance. Clin Cancer Res 14(4):1050-1058.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.4
, pp. 1050-1058
-
-
Lu, S.1
Simin, K.2
Khan, A.3
Mercurio, A.M.4
-
17
-
-
84928619768
-
Upregulation of integrin β4 promotes epithelial-mesenchymal transition and is a novel prognostic marker in pancreatic ductal adenocarcinoma
-
Masugi Y, et al. (2015) Upregulation of integrin β4 promotes epithelial-mesenchymal transition and is a novel prognostic marker in pancreatic ductal adenocarcinoma. Lab Invest 95(3):308-319.
-
(2015)
Lab Invest
, vol.95
, Issue.3
, pp. 308-319
-
-
Masugi, Y.1
-
18
-
-
84971572365
-
Elevated integrin α6β4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer
-
Stewart RL, et al. (2016) Elevated integrin α6β4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer. Hum Pathol 54: 174-183.
-
(2016)
Hum Pathol
, vol.54
, pp. 174-183
-
-
Stewart, R.L.1
-
19
-
-
85006368393
-
Refinement of triple-negative breast cancer molecular subtypes: Implications for neoadjuvant chemotherapy selection
-
Lehmann BD, et al. (2016) Refinement of triple-negative breast cancer molecular subtypes: Implications for neoadjuvant chemotherapy selection. PLoS One 11(6): e0157368.
-
(2016)
PLoS One
, vol.11
, Issue.6
, pp. e0157368
-
-
Lehmann, B.D.1
-
20
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, et al. (2011) Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 121(7):2750-2767.
-
(2011)
J Clin Invest
, vol.121
, Issue.7
, pp. 2750-2767
-
-
Lehmann, B.D.1
-
21
-
-
0035177216
-
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
-
Elenbaas B, et al. (2001) Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev 15(1):50-65.
-
(2001)
Genes Dev
, vol.15
, Issue.1
, pp. 50-65
-
-
Elenbaas, B.1
-
22
-
-
84883621632
-
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells
-
Tam WL, et al. (2013) Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell 24(3):347-364.
-
(2013)
Cancer Cell
, vol.24
, Issue.3
, pp. 347-364
-
-
Tam, W.L.1
-
23
-
-
51449085561
-
Generation of breast cancer stem cells through epithelialmesenchymal transition
-
Morel AP, et al. (2008) Generation of breast cancer stem cells through epithelialmesenchymal transition. PLoS One 3(8):e2888.
-
(2008)
PLoS One
, vol.3
, Issue.8
, pp. e2888
-
-
Morel, A.P.1
-
24
-
-
84934297821
-
Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
-
Jolly MK, et al. (2015) Implications of the hybrid epithelial/mesenchymal phenotype in metastasis. Front Oncol 5:155.
-
(2015)
Front Oncol
, vol.5
, pp. 155
-
-
Jolly, M.K.1
-
25
-
-
84857817163
-
Slug and Sox9 cooperatively determine the mammary stem cell state
-
Guo W, et al. (2012) Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 148(5):1015-1028.
-
(2012)
Cell
, vol.148
, Issue.5
, pp. 1015-1028
-
-
Guo, W.1
-
26
-
-
84941243013
-
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
-
Ye X, et al. (2015) Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature 525(7568):256-260.
-
(2015)
Nature
, vol.525
, Issue.7568
, pp. 256-260
-
-
Ye, X.1
-
27
-
-
78049453780
-
A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptorpositive breast cancer
-
Nielsen TO, et al. (2010) A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptorpositive breast cancer. Clin Cancer Res 16(21):5222-5232.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.21
, pp. 5222-5232
-
-
Nielsen, T.O.1
-
28
-
-
62449131093
-
Supervised risk predictor of breast cancer based on intrinsic subtypes
-
Parker JS, et al. (2009) Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 27(8):1160-1167.
-
(2009)
J Clin Oncol
, vol.27
, Issue.8
, pp. 1160-1167
-
-
Parker, J.S.1
-
29
-
-
84861527388
-
The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups
-
Curtis C, et al.; METABRIC Group (2012) The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups. Nature 486(7403):346-352.
-
(2012)
Nature
, vol.486
, Issue.7403
, pp. 346-352
-
-
Curtis, C.1
-
30
-
-
79151483638
-
An online survival analysis tool to rapidly assess the effect of 22, 277 genes on breast cancer prognosis using microarray data of 1, 809 patients
-
Györffy B, et al. (2010) An online survival analysis tool to rapidly assess the effect of 22, 277 genes on breast cancer prognosis using microarray data of 1, 809 patients. Breast Cancer Res Treat 123(3):725-731.
-
(2010)
Breast Cancer Res Treat
, vol.123
, Issue.3
, pp. 725-731
-
-
Györffy, B.1
-
31
-
-
33744796255
-
P63 regulates an adhesion programme and cell survival in epithelial cells
-
Carroll DK, et al. (2006) p63 regulates an adhesion programme and cell survival in epithelial cells. Nat Cell Biol 8(6):551-561.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.6
, pp. 551-561
-
-
Carroll, D.K.1
-
32
-
-
77958517604
-
ZEB1 coordinately regulates laminin-332 and beta4 integrin expression altering the invasive phenotype of prostate cancer cells
-
Drake JM, et al. (2010) ZEB1 coordinately regulates laminin-332 and beta4 integrin expression altering the invasive phenotype of prostate cancer cells. J Biol Chem 285(44):33940-33948.
-
(2010)
J Biol Chem
, vol.285
, Issue.44
, pp. 33940-33948
-
-
Drake, J.M.1
-
33
-
-
85114272939
-
Tumor budding: The name is EMT. Partial EMT
-
Grigore AD, Jolly MK, Jia D, Farach-Carson MC, Levine H (2016) Tumor budding: The name is EMT. Partial EMT. J Clin Med 5(5):E51.
-
(2016)
J Clin Med
, vol.5
, Issue.5
, pp. E51
-
-
Grigore, A.D.1
Jolly, M.K.2
Jia, D.3
Farach-Carson, M.C.4
Levine, H.5
-
34
-
-
84968756795
-
Stability of the hybrid epithelial/mesenchymal phenotype
-
Jolly MK, et al. (2016) Stability of the hybrid epithelial/mesenchymal phenotype. Oncotarget 7(19):27067-27084.
-
(2016)
Oncotarget
, vol.7
, Issue.19
, pp. 27067-27084
-
-
Jolly, M.K.1
-
35
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome geneexpression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
Taube JH, et al. (2010) Core epithelial-to-mesenchymal transition interactome geneexpression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci USA 107(35):15449-15454.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.35
, pp. 15449-15454
-
-
Taube, J.H.1
-
36
-
-
84960441572
-
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
-
Pattabiraman DR, et al. (2016) Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science 351(6277):aad3680.
-
(2016)
Science
, vol.351
, Issue.6277
, pp. aad3680
-
-
Pattabiraman, D.R.1
-
37
-
-
84886799733
-
Id2 complexes with the SNAG domain of Snai1 inhibiting Snai1-mediated repression of integrin β4
-
Chang C, Yang X, Pursell B, Mercurio AM (2013) Id2 complexes with the SNAG domain of Snai1 inhibiting Snai1-mediated repression of integrin β4. Mol Cell Biol 33(19): 3795-3804.
-
(2013)
Mol Cell Biol
, vol.33
, Issue.19
, pp. 3795-3804
-
-
Chang, C.1
Yang, X.2
Pursell, B.3
Mercurio, A.M.4
-
38
-
-
33746365139
-
Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes
-
Turner FE, et al. (2006) Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes. J Biol Chem 281(30):21321-21331.
-
(2006)
J Biol Chem
, vol.281
, Issue.30
, pp. 21321-21331
-
-
Turner, F.E.1
-
39
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1(5):555-567.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.5
, pp. 555-567
-
-
Ginestier, C.1
-
40
-
-
84905262730
-
Improved vectors and genome-wide libraries for CRISPR screening
-
Sanjana NE, Shalem O, Zhang F (2014) Improved vectors and genome-wide libraries for CRISPR screening. Nat Methods 11(8):783-784.
-
(2014)
Nat Methods
, vol.11
, Issue.8
, pp. 783-784
-
-
Sanjana, N.E.1
Shalem, O.2
Zhang, F.3
-
41
-
-
67650444760
-
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
-
Hu Y, Smyth GK (2009) ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. J Immunol Methods 347(1-2):70-78.
-
(2009)
J Immunol Methods
, vol.347
, Issue.1-2
, pp. 70-78
-
-
Hu, Y.1
Smyth, G.K.2
-
42
-
-
84876996918
-
TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
-
Kim D, et al. (2013) TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 14(4):R36.
-
(2013)
Genome Biol
, vol.14
, Issue.4
, pp. R36
-
-
Kim, D.1
-
43
-
-
84928987900
-
HTSeq: A Python framework to work with highthroughput sequencing data
-
Anders S, Pyl PT, Huber W (2015) HTSeq: A Python framework to work with highthroughput sequencing data. Bioinformatics 31(2):166-169.
-
(2015)
Bioinformatics
, vol.31
, Issue.2
, pp. 166-169
-
-
Anders, S.1
Pyl, P.T.2
Huber, W.3
-
44
-
-
84924629414
-
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
-
Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15(12):550.
-
(2014)
Genome Biol
, vol.15
, Issue.12
, pp. 550
-
-
Love, M.I.1
Huber, W.2
Anders, S.3
-
45
-
-
3142756502
-
Open source clustering software
-
de Hoon MJ, Imoto S, Nolan J, Miyano S (2004) Open source clustering software. Bioinformatics 20(9):1453-1454.
-
(2004)
Bioinformatics
, vol.20
, Issue.9
, pp. 1453-1454
-
-
De Hoon, M.J.1
Imoto, S.2
Nolan, J.3
Miyano, S.4
-
46
-
-
9444225935
-
Java Treeview: Extensible visualization of microarray data
-
Saldanha AJ (2004) Java Treeview: Extensible visualization of microarray data. Bioinformatics 20(17):3246-3248.
-
(2004)
Bioinformatics
, vol.20
, Issue.17
, pp. 3246-3248
-
-
Saldanha, A.J.1
-
47
-
-
84933036123
-
The European Genome-Phenome Archive of human data consented for biomedical research
-
Lappalainen I, et al. (2015) The European Genome-Phenome Archive of human data consented for biomedical research. Nat Genet 47(7):692-695.
-
(2015)
Nat Genet
, vol.47
, Issue.7
, pp. 692-695
-
-
Lappalainen, I.1
-
48
-
-
84883319024
-
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules
-
Basu A, et al. (2013) An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell 154(5):1151-1161.
-
(2013)
Cell
, vol.154
, Issue.5
, pp. 1151-1161
-
-
Basu, A.1
|