Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia

eLife

Volumn 7, Issue , 2018, Pages

  Opi, D Herbert ^a,b,j   Swann, Olivia ^b   Macharia, Alexander ^a   Uyoga, Sophie ^a   Band, Gavin ^c   Ndila, Carolyne M ^a   Harrison, Ewen M ^d   Thera, Mahamadou A ^e   Kone, Abdoulaye K ^e   Diallo, Dapa A ^e   Doumbo, Ogobara K ^e   Lyke, Kirsten E ^f   Plowe, Christopher V ^f   Moulds, Joann M ^g   Shebbe, Mohammed ^a   Mturi, Neema ^a   Peshu, Norbert ^a   Maitland, Kathryn ^a,h   Raza, Ahmed ^b   Kwiatkowski, Dominic P ^c,i   Rockett, Kirk A ^c   Williams, Thomas N ^a,h   Rowe, J Alexandra ^b   more..

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF BAMAKO   (Mali)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^g LifeShare Blood Centers   (United States)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

ⁱ WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^j Burnet Insititue for Medical Research and Public Health   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT RECEPTOR 1 MCC; COMPLEMENT RECEPTOR 1 SL2; HEMOGLOBIN ALPHA CHAIN; UNCLASSIFIED DRUG; CR1 PROTEIN, HUMAN;

ADULT; ALLELE; ALPHA THALASSEMIA; ARTICLE; CASE CONTROL STUDY; CEREBRAL MALARIA; COHORT ANALYSIS; CONTROLLED STUDY; DEATH; ERYTHROCYTE; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; KENYAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALIAN; NONHUMAN; PHENOTYPE; ADOLESCENT; CHILD; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDY; GENETIC POLYMORPHISM; GENETICS; INFANT; KENYA; MALE; MALI; NEWBORN; PATHOLOGY; PRESCHOOL CHILD; STATISTICAL MODEL;

ADOLESCENT; ALPHA-THALASSEMIA; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HUMANS; INFANT; INFANT, NEWBORN; KENYA; MALARIA, CEREBRAL; MALE; MALI; MODELS, STATISTICAL; POLYMORPHISM, GENETIC; RECEPTORS, COMPLEMENT 3B;

EID: 85051842826     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.31579     Document Type: Article

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