Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking

PLoS Pathogens

Volumn 14, Issue 7, 2018, Pages

  Surve, Manalee Vishnu ^a   Bhutda, Smita ^a   Datey, Akshay ^b   Anil, Anjali ^a   Rawat, Shalini ^a   Pushpakaran, Athira ^a   Singh, Dipty ^c   Kim, Kwang Sik ^d   Chakravortty, Dipshikha ^b   Banerjee, Anirban ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c NATIONAL INSTITUTE FOR RESEARCH IN REPRODUCTIVE HEALTH   (India)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALECTIN 8; PNEUMOLYSIN; UBIQUITIN; BACTERIAL PROTEIN; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; STREPTOLYSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACTERIAL CLEARANCE; BLOOD BRAIN BARRIER; BLOOD SAMPLING; BRAIN CAPILLARY ENDOTHELIAL CELL; CELL MIGRATION; CELL POPULATION; CELL VIABILITY; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HEMOLYSIS ASSAY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MOUSE; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; RNA ISOLATION; STREPTOCOCCUS PNEUMONIAE; TONOPLAST; TRANSCYTOSIS; TRANSMISSION ELECTRON MICROSCOPY; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; PNEUMOCOCCAL INFECTION; VIRULENCE;

ANIMALS; BACTERIAL PROTEINS; BLOOD-BRAIN BARRIER; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS; VIRULENCE;

EID: 85051084549     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1007168     Document Type: Article

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