pIgR and PEC AM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

Journal of Experimental Medicine

Volumn 214, Issue 6, 2017, Pages 1619-1630

  Iovino, Federico ^a,b   Engelen Lee, Joo Yeon ^c   Brouwer, Matthijs ^c   van de Beek, Diederik ^c   van der Ende, Arie ^c   Seron, Merche Valls ^c   Mellroth, Peter ^a,b   Muschiol, Sandra ^a,b   Bergstrand, Jan ^e   Widengren, Jerker ^e   Henriques Normark, Birgitta ^a,b,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^e ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL PROTEIN; CD31 ANTIGEN; CEFTRIAXONE; IMMUNOGLOBULIN RECEPTOR; PSPC PROTEIN; RRGA PROTEIN; UNCLASSIFIED DRUG; BACTERIUM ANTIBODY; FIMBRIA PROTEIN; PROTEIN BINDING; RRGA PROTEIN, STREPTOCOCCUS PNEUMONIAE; SECRETORY COMPONENT; SPSA PROTEIN, STREPTOCOCCUS PNEUMONIAE; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL LOAD; BACTERIUM PILUS; BLOOD BRAIN BARRIER; BRAIN BIOPSY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PNEUMOCOCCAL MENINGITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; STREPTOCOCCUS PNEUMONIAE; ANIMAL; BIOPSY; BRAIN; C57BL MOUSE; DRUG EFFECTS; ENDOTHELIUM CELL; ISOLATION AND PURIFICATION; MENINGITIS, BACTERIAL; METABOLISM; MICROBIOLOGY; MICROSCOPY; PATHOGENICITY; PATHOLOGY;

ADHESINS, BACTERIAL; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, CD31; BACTERIAL PROTEINS; BIOPSY; BLOOD-BRAIN BARRIER; BRAIN; ENDOTHELIAL CELLS; FIMBRIAE PROTEINS; HUMANS; MENINGITIS, BACTERIAL; MICE, INBRED C57BL; MICROSCOPY; PROTEIN BINDING; RECEPTORS, POLYMERIC IMMUNOGLOBULIN; STREPTOCOCCUS PNEUMONIAE; VIRULENCE FACTORS;

EID: 85021856297     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20161668     Document Type: Article

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